What is it about?
Data from 170 healthy donors were analyzed. The concentration of CD34+ cells in the peripheral blood (PB) and the processed volume of blood were significantly correlated to CD34+ cells yield (P < .00005 and P < .001, respectively). The G-CSF dose per m2 was significantly correlated to the concentration of CD34+ cells in the PB (P = .0003) and in the product (P = .01). Smaller BSA and less processed volume were found among female donors, who were given lesser G-CSF dose per m2, and showed lower yield compared to men.
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Why is it important?
Dose of G-CSF should probably based on BSA and not weight
Read the Original
This page is a summary of: G-CSF mobilized peripheral blood stem cell collection for allogeneic transplantation in healthy donors: Analysis of factors affecting yield, Journal of Clinical Apheresis, January 2017, Wiley,
DOI: 10.1002/jca.21524.
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