What is it about?

It is a review of the current biomaterial based methods to prevent implant related infection as well as developmental biophysical stimulation modalities such as ultrasound, magnetic and electric field exposures to potentiate the existing methods in unison

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Why is it important?

A considerable number of surgical implantations fail due to contamination of prosthesis during or post-surgical wound closure. It is important to design strategies against such biomaterial associated infection to prevent revision surgeries that can be painful and costly for the patients. This review highlights few of the existing methods and some developmental biophysical protocols that can aid in implant sterility.

Perspectives

This review summarizes briefly the different stages of implant infection by pathogenic bacteria. The authors have made earnest efforts to summarize the preventive measures against such infections with apt examples under each method. Also, the physics of few of the methods has been outlined with relevant equations and the mechanisms by schematic illustrations. The review is also written in a layman's language with technical jargon explained as when referred to.

Dr Sunil Kumar Boda
Indian Institute of Technology Indore

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This page is a summary of: Engineered biomaterial and biophysical stimulation as combinatorial strategies to address prosthetic infection by pathogenic bacteria, Journal of Biomedical Materials Research Part B Applied Biomaterials, July 2016, Wiley,
DOI: 10.1002/jbm.b.33740.
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