What is it about?
Punch biopsy followed by microscopy is an invasive technique still considered to be the gold standard for assessment of burn wound healing. In the present study, we have reported an autofluorescence based non-invasive, pain-free approach to quantify collagen during burn wound healing. This study demonstrated collagen as an optical biomarker for assessing burn wound healing
Featured Image
Why is it important?
This technique quantifies the collagen in healing tissue thereby provides the healing status in real time. The technique is also user-friendly solely dependent on excitation and emission of tissue fluorophores without the addition of any external dye molecule thus maintaining tissue architecture during the measurement.
Perspectives
Testing the clinical potential of laser-induced autofluorescence to quantify collagen in the tissue samples and validating findings of this technique with "gold standard" was challenging.
Dr Vijendra Prabhu
Manipal Academy of Higher Education
Read the Original
This page is a summary of: Probing endogenous collagen by laser-induced autofluorescence in burn wound biopsies: A pilot study, Journal of Biophotonics, May 2018, Wiley,
DOI: 10.1002/jbio.201700394.
You can read the full text:
Resources
Contributors
The following have contributed to this page
