What is it about?
ATGL in adipose tissue releases fatty acids which activates PPAR alpha signaling in the liver and protects from inflammation and controls fatty liver disease
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Why is it important?
a first link showing a cross talk between organs (white adipose tissue and liver) and the molecular mechanisms the activation of PPAR alpha in the liver depends from a fatty acid released by the adipose tissue ATGL activity
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This page is a summary of: Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia, Hepatology, January 2014, Wolters Kluwer Health,
DOI: 10.1002/hep.26732.
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