What is it about?

Here, we propose a simplified procedure to obtain highly purified primary cultures of microglial cells, i.e., the resident immune cells of the brain.

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Why is it important?

This model system allows modeling brain inflammatory processes.

Perspectives

This model system can be used for mechanistic studies or screening assays.

Dr Patrick P MICHEL
Brain and spinal cord institute

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This page is a summary of: A simplified approach for efficient isolation of functional microglial cells: Application for modeling neuroinflammatory responsesin vitro, Glia, July 2016, Wiley,
DOI: 10.1002/glia.23032.
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