What is it about?
Simple practice guide for predicting human equivalent dose from animal species for researchers
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Why is it important?
Dose translation always necessitates careful consideration of body surface area, pharmacological, physiological and anatomical factors, pharmacokinetic parameters, metabolic function, receptor, and life span
Perspectives
The pros and cons of various approaches to determine first‐in‐human dose were explained.
Dr. Anroop B Nair
King Faisal University
Read the Original
This page is a summary of: Dose translation between laboratory animals and human in preclinical and clinical phases of drug development, Drug Development Research, October 2018, Wiley,
DOI: 10.1002/ddr.21461.
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