What is it about?
High-content screening in drug discovery and basic cell biology is normally done on cells, that grow as a monolayer on the hard plastic bottom of multiwell plates. This is easy to do because cells are cultured just like in Petri dishes. However, cells behave differently in a living organism and 3D screening model that with keeping the high-throughput as well.
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This page is a summary of: Getting the whole picture: High content screening using three-dimensional cellular model systems and whole animal assays, Cytometry Part A, July 2016, Wiley,
DOI: 10.1002/cyto.a.22907.
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