What is it about?
We have developed a highly fluorescent dye that localizes strongly in liver cells and using several techniques shown that it is non-toxic and ideal for imaging of the liver. The compound emits in the red region of the visible spectrum making it perfect for whole-body imaging applications.
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Why is it important?
We have shown that our new super bright BODIPY dye is excellent at visualizing damaged liver cells in vivo, and it is better than a commercial one that is routinely used by researchers in medical diagnostics. We do not need to use albino mice to see a good fluorescence image of the liver and actually use full immune system mice.
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This page is a summary of: Enhanced In‐vivo Optical Imaging of the Inflammatory Response to Acute Liver Injury in C57Bl/6 Mice using a Highly Bright Near‐Infrared BODIPY Dye, ChemMedChem, March 2019, Wiley,
DOI: 10.1002/cmdc.201900181.
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