What is it about?

This article presents a case study on the application of artificial intelligence (AI) in diagnosing a challenging medical condition called necrotizing otitis externa (NOE). NOE is a severe infection of the external ear canal that can spread to the temporal bone and adjacent structures. The diagnosis of NOE is often difficult due to its nonspecific symptoms and potential complications. In this study, the authors explore the use of large language models (LLMs), specifically ChatGPT-3 and ChatGPT-4, to analyze objective clinical and imaging data and assist in the differential diagnosis of NOE.

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Why is it important?

The use of AI, particularly LLMs, in healthcare has gained significant attention in recent years. However, its application in complex differential diagnoses like NOE has been limited. This case study sheds light on the potential of AI in improving diagnostic accuracy and assisting healthcare professionals in challenging cases. By submitting the NOE case to LLMs and comparing their analyses with real-life clinical scenarios, the authors evaluate the capabilities of AI tools in otolaryngology. The findings highlight the challenges in diagnosing NOE and emphasize the need for comprehensive clinical evaluations, radiological imaging, and microbiological testing. The study also underscores the importance of multidisciplinary approaches and aggressive management strategies for NOE, considering its potential for serious morbidity and mortality.

Perspectives

The integration of AI into healthcare has immense potential to enhance diagnostic accuracy, improve patient outcomes, and optimize resource utilization. The case study demonstrates the utility of LLMs in assisting healthcare professionals in complex differential diagnoses. However, it also highlights the need for cautious interpretation and validation of AI-generated results, as they should be used as decision support tools rather than replacing clinical expertise. The successful application of AI in diagnosing NOE encourages further research and development in the field of otolaryngology. As AI technologies continue to evolve, they hold promise in revolutionizing medical practice and providing more efficient and accurate diagnoses. It is crucial for healthcare professionals to stay abreast of these advancements and leverage AI tools responsibly, ensuring their integration into the clinical workflow for improved patient care.

Dr alberto maria saibene
Universita degli Studi di Milano

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This page is a summary of: Are artificial intelligence large language models a reliable tool for difficult differential diagnosis? An a posteriori analysis of a peculiar case of necrotizing otitis externa, Clinical Case Reports, September 2023, Wiley,
DOI: 10.1002/ccr3.7933.
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