Biological screening, DNA binding and molecular docking of novel Cu(II), Pd(II) and Ag(I) complexes

What is it about?

In this study three new Cu (II), Pd (II) and Ag (I) complexes have been prepared and characterized via physicochemical measurements, density functional theory calculations and spectral analyses. Anti‐pathogenic screening demonstrated that the prepared compounds show good antimicrobial activity against various microorganisms as compared to the control. Moreover, the interaction of CT‐DNA with the studied complexes has been effectively estimated using electronic absorption, viscosity measurements and gel electrophoresis .These biological results from our investigation would be beneficial in investigating DNA interaction when exposed to metal complexes and may lead to an improvement in metal‐based therapeutic drugs

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