What is it about?
(E)-4-((2-hydroxyphenyl)diazenyl)-3-phenyl-1H-pyrazol-5(4H)-one, HL, and its Ni(II), Pd(II) and Pt(II) complexes were synthesized and the biological activity was evaluated for antitumor, antioxidant and antimicrobial activity as well as DNA cleavage.
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Why is it important?
The absolute necessity to fight some class of tumor is perceived as serious health concerns, so the discovery and development of effective anticancer agents are urgently needed.
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This page is a summary of: New Ni(II), Pd(II) and Pt(II) complexes coordinated to azo pyrazolone ligand with a potent anti-tumor activity: Synthesis, characterization, DFT and DNA cleavage studies, Applied Organometallic Chemistry, October 2017, Wiley,
DOI: 10.1002/aoc.4104.
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