What is it about?
The manuscript describes the design, synthesis and validation of the use of the peptidomimetics, biological activity of which can be efficiently controlled by light.
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Why is it important?
First of all, chemists and biochemists can use the developed approach to incorporate the photoswitchable unit when designing new peptidomimetics with potentially useful biological activity, Confining the biological activity into strict temporal and spatial boundaries by light beams can be a basis of novel biotechnology techniques to be used in biological screening, for example, to miniaturize and automate the assays.
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This page is a summary of: Controlling Biological Activity with Light: Diarylethene-Containing Cyclic Peptidomimetics, Angewandte Chemie, February 2014, Wiley,
DOI: 10.1002/ange.201310019.
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