What is it about?

What happens to the brain when it takes a beating

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Why is it important?

This is the first study to follow lab mice with mild head injuries over the course of their lifetimes — 27 months — We found that even one mild concussive hit to an adolescent mouse’s brain touches off “a lifelong degenerative process.” If this single mouse study proves relevant to human experience, it would suggest that just one concussion — the kind of head injury a young person generally recovers from quickly, with no outward signs of trouble — can continue to produce signals at a cellular level in the brain that later interact with the normal aging process in dramatic ways.

Perspectives

TBI or repetitive concussion: “should be studied and treated, not only as an acute event, but as a chronic health condition.”

Benoit Mouzon
Roskamp Institute

Read the Original

This page is a summary of: Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury, Annals of Clinical and Translational Neurology, December 2017, Wiley,
DOI: 10.1002/acn3.510.
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