What is it about?
We show axonal degeneration in the cornea of patients with multiple sclerosis using the rapid non-invasive ophthalmic technique of corneal confocal microscopy. We also show increased numbers of antigen presenting cells in the cornea of patients with MS.
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Why is it important?
It provides a rapid non-invasive imaging method to identify neurodegeneration in multiple sclerosis and may be used to track progression of axonal loss and repair with therapy, particularly in clinical trials.
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This page is a summary of: Use of Corneal Confocal Microscopy to Detect Corneal Nerve Loss and Increased Dendritic Cells in Patients With Multiple Sclerosis, JAMA Ophthalmology, July 2017, American Medical Association (AMA),
DOI: 10.1001/jamaophthalmol.2017.1590.
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