What is it about?

We show axonal degeneration in the cornea of patients with multiple sclerosis using the rapid non-invasive ophthalmic technique of corneal confocal microscopy. We also show increased numbers of antigen presenting cells in the cornea of patients with MS.

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Why is it important?

It provides a rapid non-invasive imaging method to identify neurodegeneration in multiple sclerosis and may be used to track progression of axonal loss and repair with therapy, particularly in clinical trials.

Perspectives

This is an innovative approach to quantifying axonal loss in multiple sclerosis

Professor Rayaz Ahmed Malik
Weill Cornell Medicine-Qatar

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This page is a summary of: Use of Corneal Confocal Microscopy to Detect Corneal Nerve Loss and Increased Dendritic Cells in Patients With Multiple Sclerosis, JAMA Ophthalmology, July 2017, American Medical Association (AMA),
DOI: 10.1001/jamaophthalmol.2017.1590.
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