All Stories

  1. CopC Protein from Pseudomonas fluorescens SBW25 Features a Conserved Novel High-Affinity Cu(II) Binding Site

    Article • Inorganic Chemistry, March 2015, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  2. The functional roles of the three copper sites associated with the methionine-rich insert in the multicopper oxidase CueO fromE. coli

    Article • Metallomics, January 2015, Oxford University Press (OUP)

    Dr Zhiguang Xiao

  3. A set of robust fluorescent peptide probes for quantification of Cu(ii) binding affinities in the micromolar to femtomolar range

    Article • Metallomics, January 2015, Oxford University Press (OUP)

    Dr Zhiguang Xiao

  4. Glutaredoxin1 protects neuronal cells from copper-induced toxicity

    Article • BioMetals, May 2014, Springer Science + Business Media

    Dr Zhiguang Xiao

  5. An integrated study of the affinities of the Aβ16 peptide for Cu(i) and Cu(ii): implications for the catalytic production of reactive oxygen species

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Dr Zhiguang Xiao

  6. Redox sulfur chemistry of the copper chaperone Atox1 is regulated by the enzyme glutaredoxin 1, the reduction potential of the glutathione couple GSSG/2GSH and the availability of Cu(i)

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Dr Zhiguang Xiao

  7. Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Dr Zhiguang Xiao

  8. Interaction of cisplatin and analogue Pt(en)Cl2 with the copper metallo-chaperone Atox1

    Article • Metallomics, January 2013, Oxford University Press (OUP)

    Dr Zhiguang Xiao, Dr Linda Feketeova

  9. Evaluation of quantitative probes for weaker Cu(i) binding sites completes a set of four capable of detecting Cu(i) affinities from nanomolar to attomolar

    Article • Metallomics, January 2013, Oxford University Press (OUP)

    Dr Zhiguang Xiao

  10. PcoE — A metal sponge expressed to the periplasm of copper resistance Escherichia coli. Implication of its function role in copper resistance

    Article • Journal of Inorganic Biochemistry, October 2012, Elsevier

    Dr Zhiguang Xiao

  11. Copper complexes of a novel non-innocent quadridentate ligand

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Professor Jonathan White, Dr Zhiguang Xiao

  12. The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells

    Article • Chemical Science, January 2012, Royal Society of Chemistry

    Dr Zhiguang Xiao

  13. Molecular Basis of the Cooperative Binding of Cu(I) and Cu(II) to the CopK Protein from Cupriavidus metallidurans CH34

    Article • Biochemistry, November 2011, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  14. ChemInform Abstract: Metallo-Oxidase Enzymes: Design of Their Active Sites

    Article • ChemInform, June 2011, Wiley

    Dr Zhiguang Xiao

  15. Water-soluble Bis(thiosemicarbazonato)copper(II) Complexes

    Article • Australian Journal of Chemistry, January 2011, CSIRO Publishing

    Professor Jonathan White, Dr Zhiguang Xiao

  16. Metallo-oxidase Enzymes: Design of their Active Sites

    Article • Australian Journal of Chemistry, January 2011, CSIRO Publishing

    Dr Zhiguang Xiao

  17. Solvation Effects on S K-Edge XAS Spectra of Fe−S Proteins: Normal and Inverse Effects on WT and Mutant Rubredoxin

    Article • Journal of the American Chemical Society, September 2010, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  18. ChemInform Abstract: The Challenges of Determining Metal-Protein Affinities

    Article • ChemInform, July 2010, Wiley

    Dr Zhiguang Xiao

  19. A Water-Soluble Bis(thiosemicarbazone) Ligand. A Sensitive Probe and Metal Buffer for Zinc

    Article • Inorganic Chemistry, April 2010, American Chemical Society (ACS)

    Professor Jonathan White, Dr Zhiguang Xiao

  20. Reaction Mechanisms of the Multicopper Oxidase CueO from Escherichia coli Support Its Functional Role as a Cuprous Oxidase

    Article • Journal of the American Chemical Society, February 2010, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  21. The challenges of determining metal–protein affinities

    Article • Natural Product Reports, January 2010, Royal Society of Chemistry

    Dr Zhiguang Xiao

  22. Metal Binding Affinities of Arabidopsis Zinc and Copper Transporters: Selectivities Match the Relative, but Not the Absolute, Affinities of their Amino-Terminal Domains,

    Article • Biochemistry, December 2009, American Chemical Society (ACS)

    Dr Zhiguang Xiao, Dr David W Keizer

  23. Unprecedented Binding Cooperativity between Cu I and Cu II in the Copper Resistance Protein CopK from Cupriavidus metallidurans CH34: Implications from Structural Studies by NMR Spectroscopy and X-Ray Crystallography

    Article • Journal of the American Chemical Society, March 2009, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  24. Metal specificities of Arabidopsis zinc and copper transport proteins match the relative, but not the absolute, affinities of their N-terminal domains

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Dr Zhiguang Xiao

  25. Interaction of cisplatin and analogues with a Met-rich protein site

    Article • JBIC Journal of Biological Inorganic Chemistry, November 2008, Springer Science + Business Media

    Dr Zhiguang Xiao

  26. Copper Resistance inE. coli: The Multicopper Oxidase PcoA Catalyzes Oxidation of Copper(I) in CuICuII‐PcoC

    Article • ChemBioChem, July 2008, Wiley

    Dr Zhiguang Xiao

  27. Transfer of Copper between Bis(thiosemicarbazone) Ligands and Intracellular Copper-Binding Proteins. Insights into Mechanisms of Copper Uptake and Hypoxia Selectivity

    Article • Inorganic Chemistry, May 2008, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  28. Electron paramagnetic resonance characterization of the copper-resistance protein PcoC from Escherichia coli

    Article • JBIC Journal of Biological Inorganic Chemistry, April 2008, Springer Science + Business Media

    Dr Zhiguang Xiao

  29. Protonless 13 C direct detection NMR: Characterization of the 37 kDa trimeric protein CutA1

    Article • Proteins Structure Function and Bioinformatics, September 2007, Wiley

    Dr Zhiguang Xiao

  30. Conserved Mechanism of Copper Binding and Transfer. A Comparison of the Copper-Resistance Proteins PcoC from Escherichia coli and CopC from Pseudomonas syringae

    Article • Inorganic Chemistry, May 2007, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  31. Copper and Alzheimer's disease

    Article • Current Opinion in Chemical Biology, April 2007, Elsevier

    Dr Zhiguang Xiao

  32. Determinants of the reduction potential in rubredoxins, the simplest iron-sulfur electrontransfer proteins

    Article • January 2007, Royal Society of Chemistry

    Dr Zhiguang Xiao

  33. Intermolecular Transfer of Copper Ions from the CopC Protein of Pseudomonas syringae . Crystal Structures of Fully Loaded Cu I Cu II Forms

    Article • Journal of the American Chemical Society, May 2006, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  34. CopC Protein from Pseudomonas s yringae :  Intermolecular Transfer of Copper from Both the Copper(I) and Copper(II) Sites

    Article • Inorganic Chemistry, July 2005, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  35. C-Terminal Domain of the Membrane Copper Transporter Ctr1 from Saccharomyces cerevisiae Binds Four Cu(I) Ions as a Cuprous-Thiolate Polynuclear Cluster:  Sub-femtomolar Cu(I) Affinity of Three Proteins Involved in Copper Trafficking

    Article • Journal of the American Chemical Society, March 2004, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  36. Metal binding in CopC from P. syringae pathovar tomato

    Article • Journal of Inorganic Biochemistry, July 2003, Elsevier

    Dr Zhiguang Xiao

  37. The C-terminal domain of the membrane copper pump Ctrl in yeast binds Cu as a cuprous-thiolate polynuclear cluster

    Article • Journal of Inorganic Biochemistry, July 2003, Elsevier

    Dr Zhiguang Xiao

  38. Application of NMRD to Hydration of Rubredoxin and a Variant Containing a (Cys-S)3FeIII(OH) Site

    Article • Biophysical Journal, January 2003, Elsevier

    Professor Claudio Luchinat, Dr Zhiguang Xiao

  39. Removal of a cysteine ligand from rubredoxin: assembly of Fe2S2 and Fe(S-Cys)3(OH) centres

    Article • JBIC Journal of Biological Inorganic Chemistry, September 2002, Springer Science + Business Media

    Dr Zhiguang Xiao

  40. A C-terminal domain of the membrane copper pump Ctr1 exchanges copper(i) with the copper chaperone Atx1

    Article • Chemical Communications, February 2002, Royal Society of Chemistry

    Dr Zhiguang Xiao

  41. Redox thermodynamics of mutant forms of the rubredoxin from Clostridiumpasteurianum: identification of a stable FeIII(S-Cys)3(OH) centre in the C6S mutant

    Article • JBIC Journal of Biological Inorganic Chemistry, May 2001, Springer Science + Business Media

    Dr Zhiguang Xiao

  42. The dependence of reversible potentials on the form of modification of edge plane pyrolytic graphite electrodes in voltammetric studies on rubredoxin and ferredoxin from Clostridium pasteurianum

    Article • Electrochemistry Communications, August 1999, Elsevier

    Dr Zhiguang Xiao

  43. Rubredoxin fromClostridium pasteurianum. Structures of G10A, G43A and G10VG43A mutant proteins. Mutation of conserved glycine 10 to valine causes the 9–10 peptide link to invert

    Article • Acta Crystallographica Section D Biological Crystallography, May 1999, International Union of Crystallography

    Dr Zhiguang Xiao

  44. The Rubredoxin from Clostridium pasteurianum :  Mutation of the Iron Cysteinyl Ligands to Serine. Crystal and Molecular Structures of Oxidized and Dithionite-Treated Forms of the Cys42Ser Mutant

    Article • Journal of the American Chemical Society, May 1998, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  45. Rubredoxin from Clostridium pasteurianum : Mutation of the Conserved Cysteine and Glycine Residues

    Article • November 1996, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  46. Dioxomolybdenum(VI) Complexes of Tripodal Nitrogen-Donor Ligands:  Syntheses and Spectroscopic, Structural, and Electrochemical Studies, Including the Generation of EPR-Active Molybdenum(V) Species in Solution

    Article • Inorganic Chemistry, January 1996, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  47. The Rubredoxin from Clostridium pasteurianum :  Mutation of the Conserved Glycine Residues 10 and 43 to Alanine and Valine

    Article • Inorganic Chemistry, January 1996, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  48. Complexes Containing cis- [Mo V O 2 ] + and cis -[Mo V O(OH)] 2+ Centers

    Article • Journal of the American Chemical Society, January 1996, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  49. A Catalytic Cycle Related to Molybdenum Enzymes Containing [Mo VI O 2 ] 2+ Oxidized Active Sites

    Article • Inorganic Chemistry, January 1996, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  50. Dioxomolybdenum(VI) Complexes of Tripodal Nitrogen-Donor Ligands: Syntheses and Spectroscopic, Structural, and Electrochemical Studies, Including the Generation of EPR-Active Molybdenum(V) Species in Solution

    Article • Inorganic Chemistry, November 1995, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  51. Isovalent and Mixed-Valent Dinuclear .mu.-Oxo and .mu.-Oxo .mu.-Disulfido Complexes of Molybdenum(V) and Molybdenum(VI)

    Article • Inorganic Chemistry, August 1994, American Chemical Society (ACS)

    Dr Zhiguang Xiao

  52. The cis-dioxomolybdenum(V) radical anion, [{HB(Me2C2N3)3}MoO2(SPh)]?

    Article • Journal of the Chemical Society Chemical Communications, January 1994, Royal Society of Chemistry

    Dr Zhiguang Xiao

  53. A single model displaying all the important centers and processes involved in catalysis by molybdoenzymes containing [MoVIO2]2+ active sites

    Article • Journal of the American Chemical Society, November 1992, American Chemical Society (ACS)

    Dr Zhiguang Xiao