All Stories

  1. Norepinephrine improves de novo emergence of hematopoietic cells in human pluripotent stem cell differentiation cultures

    Article • Experimental Hematology, August 2014, Elsevier

    Professor Zaal Kokaia

  2. The age and genomic integrity of neurons after cortical stroke in humans

    Article • Nature Neuroscience, April 2014, Springer Science + Business Media

    Professor Zaal Kokaia

  3. Human Fetal Striatum-Derived Neural Stem (NS) Cells Differentiate to Mature Neurons In Vitro and In Vivo

    Article • Current Stem Cell Research & Therapy, April 2014, Bentham Science Publishers

    Professor Zaal Kokaia

  4. FoxJ1-expressing cells contribute to neurogenesis in forebrain of adult rats: Evidence from in vivo electroporation combined with piggyBac transposon

    Article • Experimental Cell Research, November 2013, Elsevier

    Professor Zaal Kokaia

  5. Norepinephrine improves the generation of hematopoietic cells from human pluripotent stem cells

    Article • Experimental Hematology, August 2013, Elsevier

    Professor Zaal Kokaia

  6. Grafted human neural stem cells enhance several steps of endogenous neurogenesis and improve behavioral recovery after middle cerebral artery occlusion in rats

    Article • Neurobiology of Disease, April 2013, Elsevier

    Professor Zaal Kokaia

  7. Embryonic Stem Cell‐Derived Neural Stem Cells Fuse with Microglia and Mature Neurons

    Article • Stem Cells, November 2012, Oxford University Press (OUP)

    Professor Zaal Kokaia, Henrik Ahlenius

  8. Cross-talk between neural stem cells and immune cells: the key to better brain repair?

    Article • Nature Neuroscience, July 2012, Springer Science + Business Media

    Professor Zaal Kokaia

  9. Ectopic ependymal cells in striatum accompany neurogenesis in a rat model of stroke

    Article • Neuroscience, July 2012, Elsevier

    Professor Zaal Kokaia

  10. Human‐Induced Pluripotent Stem Cells form Functional Neurons and Improve Recovery After Grafting in Stroke‐Damaged Brain

    Article • Stem Cells, May 2012, Oxford University Press (OUP)

    Professor Zaal Kokaia, Henrik Ahlenius

  11. Societal Value of Stem Cell Therapy in Stroke – A Modeling Study

    Article • Cerebrovascular Diseases, January 2012, Karger Publishers

    Professor Zaal Kokaia

  12. Expression analysis of pluripotency-associated genes in human fetal cortical and striatal neural stem cells during differentiation

    Article • Translational Neuroscience, January 2012, De Gruyter

    Professor Zaal Kokaia

  13. Stem cell repair of striatal ischemia

    Article • January 2012, Elsevier

    Professor Zaal Kokaia

  14. Meteorin is a Chemokinetic Factor in Neuroblast Migration and Promotes Stroke-Induced Striatal Neurogenesis

    Article • Journal of Cerebral Blood Flow & Metabolism, November 2011, SAGE Publications

    Professor Zaal Kokaia

  15. Neural Stem Cell-Based Therapy for Ischemic Stroke

    Article • Translational Stroke Research, August 2011, Springer Science + Business Media

    Professor Zaal Kokaia

  16. Stem Cell Research in Stroke

    Article • Stroke, August 2011, Wolters Kluwer Health

    Professor Zaal Kokaia

  17. Spatio-temporal dynamics, differentiation and viability of human neural stem cells after implantation into neonatal rat brain

    Article • European Journal of Neuroscience, June 2011, Wiley

    Professor Zaal Kokaia

  18. Selective depletion of Mac-1-expressing microglia in rat subventricular zone does not alter neurogenic response early after stroke

    Article • Experimental Neurology, June 2011, Elsevier

    Professor Zaal Kokaia

  19. Functional integration of new hippocampal neurons following insults to the adult brain is determined by characteristics of pathological environment

    Article • Experimental Neurology, June 2011, Elsevier

    Professor Zaal Kokaia

  20. Towards Clinical Application of Stem Cells in Neurodegenerative Disorders

    Article • January 2011, Springer Science + Business Media

    Professor Zaal Kokaia

  21. Perturbed cellular response to brain injury during aging

    Article • Ageing Research Reviews, January 2011, Elsevier

    Professor Zaal Kokaia

  22. Neurogenesis from Endogenous Neural Stem Cells After Stroke: A Future Therapeutic Target to Promote Functional Restoration?

    Article • January 2011, Springer Science + Business Media

    Professor Zaal Kokaia

  23. Cell Number and Timing of Transplantation Determine Survival of Human Neural Stem Cell Grafts in Stroke-Damaged Rat Brain

    Article • Journal of Cerebral Blood Flow & Metabolism, June 2010, SAGE Publications

    Professor Zaal Kokaia

  24. Stem cells in human neurodegenerative disorders — time for clinical translation?

    Article • Journal of Clinical Investigation, January 2010, American Society for Clinical Investigation

    Professor Zaal Kokaia

  25. Isolation and Generation of Neurosphere Cultures from Embryonic and Adult Mouse Brain

    Article • January 2010, Springer Science + Business Media

    Professor Zaal Kokaia, Henrik Ahlenius

  26. Emerging concepts in neural stem cell research: autologous repair and cell-based disease modelling

    Article • The Lancet Neurology, September 2009, Elsevier

    Professor Zaal Kokaia

  27. Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease

    Article • Trends in Pharmacological Sciences, May 2009, Elsevier

    Professor Zaal Kokaia

  28. Neural Stem and Progenitor Cells Retain Their Potential for Proliferation and Differentiation into Functional Neurons Despite Lower Number in Aged Brain

    Article • Journal of Neuroscience, April 2009, Society for Neuroscience

    Professor Zaal Kokaia, Henrik Ahlenius

  29. Neurobiology of Postischemic Recuperation in the Aged Mammalian Brain

    Article • March 2009, Oxford University Press (OUP)

    Professor Zaal Kokaia

  30. Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke

    Article • Nature Neuroscience, February 2009, Springer Science + Business Media

    Professor Zaal Kokaia

  31. Brain inflammation and adult neurogenesis: The dual role of microglia

    Article • Neuroscience, February 2009, Elsevier

    Professor Zaal Kokaia

  32. Long‐term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke

    Article • Glia, December 2008, Wiley

    Professor Zaal Kokaia, Jalal Taneera

  33. Inflammation Regulates Functional Integration of Neurons Born in Adult Brain

    Article • Journal of Neuroscience, November 2008, Society for Neuroscience

    Professor Zaal Kokaia

  34. MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain

    Article • Molecular and Cellular Neuroscience, October 2008, Elsevier

    Professor Zaal Kokaia

  35. Ultrastructural and antigenic properties of neural stem cells and their progeny in adult rat subventricular zone

    Article • Glia, August 2008, Wiley

    Professor Zaal Kokaia, Henrik Ahlenius

  36. Pax6 promotes neurogenesis in human neural stem cells

    Article • Molecular and Cellular Neuroscience, August 2008, Elsevier

    Professor Zaal Kokaia

  37. Suppression of Stroke-Induced Progenitor Proliferation in Adult Subventricular Zone by Tumor Necrosis Factor Receptor 1

    Article • Journal of Cerebral Blood Flow & Metabolism, May 2008, SAGE Publications

    Professor Zaal Kokaia, Henrik Ahlenius

  38. Long-Term Neuroblast Migration Along Blood Vessels in an Area With Transient Angiogenesis and Increased Vascularization After Stroke

    Article • Stroke, November 2007, Wolters Kluwer Health

    Professor Zaal Kokaia

  39. The Response of the Aged Brain to Stroke: Too Much, Too Soon?

    Article • Current Neurovascular Research, August 2007, Bentham Science Publishers

    Professor Zaal Kokaia

  40. Survival, migration and neuronal differentiation of human fetal striatal and cortical neural stem cells grafted in stroke‐damaged rat striatum

    Article • European Journal of Neuroscience, August 2007, Wiley

    Professor Zaal Kokaia

  41. Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability

    Article • Neuron, December 2006, Elsevier

    Professor Zaal Kokaia

  42. Human fetal cortical and striatal neural stem cells generate region‐specific neurons in vitro and differentiate extensively to neurons after intrastriatal transplantation in neonatal rats

    Article • Journal of Neuroscience Research, October 2006, Wiley

    Professor Zaal Kokaia

  43. Intracerebral Infusion of Glial Cell Line-Derived Neurotrophic Factor Promotes Striatal Neurogenesis After Stroke in Adult Rats

    Article • Stroke, September 2006, Wolters Kluwer Health

    Professor Zaal Kokaia, Henrik Ahlenius

  44. Prostaglandin E2 and BDNF levels in rat hippocampus are negatively correlated with status epilepticus severity: No impact on survival of seizure-generated neurons

    Article • Neurobiology of Disease, July 2006, Elsevier

    Professor Zaal Kokaia

  45. Regulation of Stroke-Induced Neurogenesis in Adult Brain--Recent Scientific Progress

    Article • Cerebral Cortex, July 2006, Oxford University Press (OUP)

    Professor Zaal Kokaia

  46. Stem cells for the treatment of neurological disorders

    Article • Nature, June 2006, Springer Science + Business Media

    Professor Zaal Kokaia

  47. Persistent Production of Neurons from Adult Brain Stem Cells During Recovery after Stroke

    Article • Stem Cells, March 2006, Oxford University Press (OUP)

    Professor Zaal Kokaia, Henrik Ahlenius

  48. Stem cell therapy for human brain disorders

    Article • Kidney International, November 2005, Elsevier

    Professor Zaal Kokaia

  49. Quantitative analysis of the generation of different striatal neuronal subtypes in the adult brain following excitotoxic injury

    Article • Experimental Neurology, September 2005, Elsevier

    Professor Zaal Kokaia

  50. Is there room for regeneration: Spontaneous versus induced neurogenesis

    Article • August 2005

    Professor Zaal Kokaia

  51. Stroke-Induced Neurogenesis in Aged Brain

    Article • Stroke, August 2005, Wolters Kluwer Health

    Professor Zaal Kokaia

  52. Microglia-derived tumor necrosis factor-α exaggerates death of newborn hippocampal progenitor cells in vitro

    Article • Journal of Neuroscience Research, January 2005, Wiley

    Professor Zaal Kokaia

  53. Stem cell therapy for human neurodegenerative disorders–how to make it work

    Article • Nature Reports Stem Cells, July 2004, Springer Science + Business Media

    Professor Zaal Kokaia

  54. Neurogenesis in Stroke and Epilepsy

    Article • January 2004, Springer Science + Business Media

    Professor Zaal Kokaia

  55. Elevated GDNF levels following viral vector-mediated gene transfer can increase neuronal death after stroke in rats

    Article • Neurobiology of Disease, December 2003, Elsevier

    Professor Zaal Kokaia

  56. Phenotypic and molecular identity of cells in the adult subventricular zone

    Article • Molecular and Cellular Neuroscience, November 2003, Elsevier

    Professor Zaal Kokaia

  57. Intraventricular Infusion of TrkB-Fc Fusion Protein Promotes Ischemia-Induced Neurogenesis in Adult Rat Dentate Gyrus

    Article • Stroke, November 2003, Wolters Kluwer Health

    Professor Zaal Kokaia

  58. Inflammation is detrimental for neurogenesis in adult brain

    Article • Proceedings of the National Academy of Sciences, October 2003, Proceedings of the National Academy of Sciences

    Professor Zaal Kokaia

  59. Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABAb autoreceptors in layer III of the entorhinal cortex

    Article • Neurobiology of Disease, August 2003, Elsevier

    Professor Zaal Kokaia

  60. Suppression of limbic motor seizures by electrical stimulation in thalamic reticular nucleus

    Article • Experimental Neurology, June 2003, Elsevier

    Professor Zaal Kokaia

  61. Anterograde delivery of brain‐derived neurotrophic factor to striatum via nigral transduction of recombinant adeno‐associated virus increases neuronal death but promotes neurogenic response following stroke

    Article • European Journal of Neuroscience, June 2003, Wiley

    Professor Zaal Kokaia

  62. Generalization of rapidly recurring seizures is suppressed in mice lacking glial cell line-derived neurotrophic factor family receptor α2

    Article • Neuroscience, May 2003, Elsevier

    Professor Zaal Kokaia

  63. Neurogenesis after ischaemic brain insults

    Article • Current Opinion in Neurobiology, February 2003, Elsevier

    Professor Zaal Kokaia

  64. Neurotrophic factors and brain ischemia

    Article • European Neuropsychopharmacology, October 2002, Elsevier

    Professor Zaal Kokaia

  65. Peptide receptors: Anything different from targeting amine systems?

    Article • European Neuropsychopharmacology, October 2002, Elsevier

    Professor Zaal Kokaia

  66. Neuronal replacement from endogenous precursors in the adult brain after stroke

    Article • Nature Reports Stem Cells, August 2002, Springer Science + Business Media

    Professor Zaal Kokaia

  67. Neuropathological and Behavioral Consequences of Adeno-Associated Viral Vector-Mediated Continuous Intrastriatal Neurotrophin Delivery in a Focal Ischemia Model in Rats

    Article • Neurobiology of Disease, March 2002, Elsevier

    Professor Zaal Kokaia

  68. Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

    Article • Proceedings of the National Academy of Sciences, November 2001, Proceedings of the National Academy of Sciences

    Professor Zaal Kokaia

  69. Changes in GABAB receptor immunoreactivity after recurrent seizures in rats

    Article • Neuroscience Letters, November 2001, Elsevier

    Professor Zaal Kokaia

  70. Stereological assessment of vulnerability of immunocytochemically identified striatal and hippocampal neurons after global cerebral ischemia in rats

    Article • Brain Research, September 2001, Elsevier

    Professor Zaal Kokaia

  71. Stroke induces widespread changes of gene expression for glial cell line-derived neurotrophic factor family receptors in the adult rat brain

    Article • Neuroscience, September 2001, Elsevier

    Professor Zaal Kokaia

  72. N‐methyl‐d‐aspartate receptor‐mediated increase of neurogenesis in adult rat dentate gyrus following stroke

    Article • European Journal of Neuroscience, July 2001, Wiley

    Professor Zaal Kokaia

  73. Upregulation of p75 Neurotrophin Receptor after Stroke in Mice Does Not Contribute to Differential Vulnerability of Striatal Neurons

    Article • Experimental Neurology, June 2001, Elsevier

    Professor Zaal Kokaia

  74. Enriched environment influences brain-derived neurotrophic factor levels in rat forebrain after focal stroke

    Article • Neuroscience Letters, June 2001, Elsevier

    Professor Zaal Kokaia

  75. In Situ Hybridization Histochemistry

    Article • May 2001, Wiley

    Professor Zaal Kokaia

  76. Neurotrophic factors and brain ischemia

    Article • European Neuropsychopharmacology, January 2001, Elsevier

    Professor Zaal Kokaia

  77. Monoamine—neuropeptide interactions

    Article • European Neuropsychopharmacology, January 2001, Elsevier

    Professor Zaal Kokaia

  78. Development and persistence of kindling epilepsy are impaired in mice lacking glial cell line-derived neurotrophic factor family receptor α2

    Article • Proceedings of the National Academy of Sciences, October 2000, Proceedings of the National Academy of Sciences

    Professor Zaal Kokaia

  79. Seizures induce widespread upregulation of cystatin B, the gene mutated in progressive myoclonus epilepsy, in rat forebrain neurons

    Article • European Journal of Neuroscience, May 2000, Wiley

    Professor Zaal Kokaia

  80. Evidence for Neuroprotective Effects of Endogenous Brain-Derived Neurotrophic Factor after Global Forebrain Ischemia in Rats

    Article • Journal of Cerebral Blood Flow & Metabolism, November 1999, SAGE Publications

    Professor Zaal Kokaia

  81. Differential regulation of mRNAs for neuropeptide Y and its receptor subtypes in widespread areas of the rat limbic system during kindling epileptogenesis

    Article • Molecular Brain Research, September 1999, Elsevier

    Professor Zaal Kokaia

  82. GDNF family ligands and receptors are differentially regulated after brain insults in the rat

    Article • European Journal of Neuroscience, April 1999, Wiley

    Professor Zaal Kokaia

  83. Rapid Alterations of BDNF Protein Levels in the Rat Brain after Focal Ischemia: Evidence for Increased Synthesis and Anterograde Axonal Transport

    Article • Experimental Neurology, December 1998, Elsevier

    Professor Zaal Kokaia

  84. BDNF Regulates Reelin Expression and Cajal-Retzius Cell Development in the Cerebral Cortex

    Article • Neuron, August 1998, Elsevier

    Professor Zaal Kokaia

  85. Amelioration of ischaemia-induced neuronal death in the rat striatum by NGF-secreting neural stem cells

    Article • European Journal of Neuroscience, June 1998, Wiley

    Professor Zaal Kokaia

  86. Focal cerebral ischemia in rats induces expression of p75 neurotrophin receptor in resistant striatal cholinergic neurons

    Article • Neuroscience, June 1998, Elsevier

    Professor Zaal Kokaia

  87. Epileptogenesis induced by rapidly recurring seizures in genetically fast- but not slow-kindling rats

    Article • Brain Research, April 1998, Elsevier

    Professor Zaal Kokaia

  88. Neurotrophins and Kindling Epileptogenesis

    Article • January 1998, Springer Science + Business Media

    Professor Zaal Kokaia

  89. Suppression of kindling epileptogenesis in rats by intrahippocampal cholinergic grafts

    Article • European Journal of Neuroscience, January 1998, Wiley

    Professor Zaal Kokaia

  90. Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizures

    Article • Neuroscience, January 1998, Elsevier

    Professor Zaal Kokaia

  91. Apoptosis and proliferation of dentate gyrus neurons after single and intermittent limbic seizures

    Article • Proceedings of the National Academy of Sciences, September 1997, Proceedings of the National Academy of Sciences

    Professor Zaal Kokaia

  92. Effects of cholinergic denervation on seizure development and neurotrophin messenger RNA regulation in rapid hippocampal kindling

    Article • Neuroscience, July 1997, Elsevier

    Professor Zaal Kokaia

  93. Mossy fibre sprouting

    Article • Neuroreport, March 1997, Wolters Kluwer Health

    Professor Zaal Kokaia

  94. Seizure-induced differential expression of messenger RNAs for neurotrophins and their receptors in genetically fast and slow kindling rats

    Article • Neuroscience, September 1996, Elsevier

    Professor Zaal Kokaia

  95. 43 Regulation of neurotrophins in cerebral ischemia

    Article • International Journal of Developmental Neuroscience, July 1996, Wiley

    Professor Zaal Kokaia

  96. Regulation of neuronal nitric oxide synthase mRNA levels in rat brain by seizure activity

    Article • Neuroreport, May 1996, Wolters Kluwer Health

    Professor Zaal Kokaia

  97. Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat

    Article • Molecular Brain Research, May 1996, Elsevier

    Professor Zaal Kokaia

  98. Delayed kindling development after rapidly recurring seizures: relation to mossy fiber sprouting and neurotrophin, GAP-43 and dynorphin gene expression

    Article • Brain Research, March 1996, Elsevier

    Professor Zaal Kokaia

  99. Immunolesioning of basal forebrain cholinergic neurons facilitates hippocampal kindling and perturbs neurotrophin messenger RNA regulation

    Article • Neuroscience, January 1996, Elsevier

    Professor Zaal Kokaia

  100. Regulation of Brain-Derived Neurotrophic Factor Gene Expression after Transient Middle Cerebral Artery Occlusion with and without Brain Damage

    Article • Experimental Neurology, November 1995, Elsevier

    Professor Zaal Kokaia

  101. Co-expression of TrkB and TrkC receptors in CNS neurones suggests regulation by multiple neurotrophins

    Article • Neuroreport, March 1995, Wolters Kluwer Health

    Professor Zaal Kokaia

  102. Neurotrophins in Kindling Epilepsy: Neuronal Protection or Induction of Sprouting and Epileptogenesis?

    Article • January 1995, Elsevier

    Professor Zaal Kokaia

  103. List of Contributors

    Article • January 1995, Elsevier

    Professor Zaal Kokaia

  104. Seizure suppression in kindling epilepsy by intracerebral implants of GABA-but not by noradrenalinereleasing polymer matrices

    Article • Experimental Brain Research, August 1994, Springer Science + Business Media

    Professor Zaal Kokaia

  105. Seizure suppression in kindling epilepsy by intracerebral implants of GABA- but not by noradrenaline-releasing polymer matrices

    Article • Experimental Brain Research, August 1994, Springer Science + Business Media

    Professor Zaal Kokaia

  106. BDNF makes cultured dentate granule cells more resistant to hypoglycaemic damage

    Article • Neuroreport, June 1994, Wolters Kluwer Health

    Professor Zaal Kokaia

  107. Biphasic differential changes of GABAA receptor subunit mRNA levels in dentate gyrus granule cells following recurrent kindling-induced seizures

    Article • Molecular Brain Research, June 1994, Elsevier

    Professor Zaal Kokaia

  108. Brain Insults in Rats Induce Increased Expression of the BDNF Gene through Differential Use of Multiple Promoters

    Article • European Journal of Neuroscience, April 1994, Wiley

    Professor Zaal Kokaia

  109. Neurotrophins and brain insults

    Article • Trends in Neurosciences, January 1994, Elsevier

    Professor Zaal Kokaia

  110. Expression, Regulation and Receptor Distribution of Neurotrophins in the Mammalian Central Nervous System

    Article • January 1994, Elsevier

    Professor Zaal Kokaia

  111. Differential regulation of N-methyl-d-aspartate receptor subunit messenger RNAs in kindling-induced epileptogenesis

    Article • Neuroscience, November 1993, Elsevier

    Professor Zaal Kokaia

  112. Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression: regulation by glutamatergic mechanisms independent of seizure activity

    Article • Molecular Brain Research, September 1993, Elsevier

    Professor Zaal Kokaia

  113. Coexpression of neurotrophins and their receptors in neurons of the central nervous system.

    Article • Proceedings of the National Academy of Sciences, July 1993, Proceedings of the National Academy of Sciences

    Professor Zaal Kokaia

  114. Specific Functions of Grafted Locus Coeruleus Neurons in the Kindling Model of Epilepsy

    Article • Experimental Neurology, July 1993, Elsevier

    Professor Zaal Kokaia

  115. Regulation of neurotrophin and traka, trkb and trkc tyrosine kinase receptor messenger RNA expression in kindling

    Article • Neuroscience, March 1993, Elsevier

    Professor Zaal Kokaia

  116. Increased production of the TrkB protein tyrosine kinase receptor after brain insults

    Article • Neuron, February 1993, Elsevier

    Professor Zaal Kokaia

  117. Widespread increase of nerve growth factor protein in the rat forebrain after kindling-induced seizures

    Article • Brain Research, August 1992, Elsevier

    Professor Zaal Kokaia

  118. Increased levels of messenger RNAs for neurotrophic factors in the brain during kindling epileptogenesis

    Article • Neuron, July 1991, Elsevier

    Professor Zaal Kokaia