All Stories

  1. Mosaic-PICASSO: accurate crosstalk removal for multiplex fluorescence imaging

    Article • Bioinformatics, January 2024, Oxford University Press (OUP)

    Yang Liu

  2. The Amyloid Precursor Protein Modulates the Position and Length of the Axon Initial Segment

    Article • Journal of Neuroscience, January 2023, Society for Neuroscience

    Yang Liu

  3. Changes in nuclear pore numbers control nuclear import and stress response of mouse hearts

    Article • Developmental Cell, October 2022, Elsevier

    Yang Liu

  4. Redox regulation of RAD51 Cys319 and homologous recombination by peroxiredoxin 1

    Article • Redox Biology, October 2022, Elsevier

    Yang Liu

  5. Prediction of neoplastic progression in Barrett’s esophagus using nanoscale nuclear architecture mapping: a pilot study

    Article • Gastrointestinal Endoscopy, June 2022, Elsevier

    Yang Liu

  6. Ultrastructural visualization of chromatin in cancer pathogenesis using a simple small-molecule fluorescent probe

    Article • Science Advances, March 2022, American Association for the Advancement of Science

    Yang Liu

  7. The amyloid precursor protein modulates the position and length of the axon initial segment offering a new perspective on Alzheimer’s disease genetics

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Yang Liu

  8. Robust emitter localization with enhanced harmonic analysis

    Article • Optics Letters, November 2021, Optical Society of America (OSA)

    Yang Liu

  9. Enhanced super-resolution microscopy by extreme value based emitter recovery

    Article • Scientific Reports, October 2021, Springer Science + Business Media

    Yang Liu

  10. Embedded nanometer position tracking based on enhanced phasor analysis: erratum

    Article • Optics Letters, September 2021, Optical Society of America (OSA)

    Yang Liu

  11. Embedded nanometer position tracking based on enhanced phasor analysis

    Article • Optics Letters, August 2021, Optical Society of America (OSA)

    Yang Liu

  12. Application of convolutional neural networks towards nuclei segmentation in localization-based super-resolution fluorescence microscopy images

    Article • BMC Bioinformatics, June 2021, Springer Science + Business Media

    Yang Liu

  13. Integrative proteomics identifies thousands of distinct, multi-epitope, and high-affinity nanobodies

    Article • Cell Systems, March 2021, Elsevier

    Yang Liu

  14. Super-Resolution Imaging through Single-Molecule Localization

    Article • January 2021, American Institute of Physics

    Yang Liu

  15. Optimized Stochastic Optical Reconstruction Microscopy for Imaging Chromatin Structure in Pathological Tissue

    Article • Current Protocols in Cytometry, August 2020, Wiley

    Yang Liu

  16. PathSTORM: a road to early cancer detection

    Article • Molecular & Cellular Oncology, June 2020, Taylor & Francis

    Yang Liu

  17. Super-resolution localization microscopy: Toward high throughput, high quality, and low cost

    Article • APL Photonics, June 2020, American Institute of Physics

    Yang Liu

  18. Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Yang Liu

  19. Three-Dimensional Nanoscale Nuclear Architecture Mapping of Rectal Biopsies Detects Colorectal Neoplasia in Patients with Inflammatory Bowel Disease

    Article • Cancer Prevention Research, August 2019, American Association for Cancer Research (AACR)

    Yang Liu

  20. WindSTORM: Robust online image processing for high-throughput nanoscopy

    Article • Science Advances, April 2019, American Association for the Advancement of Science

    Yang Liu

  21. Concentric organization of A- and B-type lamins predicts their distinct roles in the spatial organization and stability of the nuclear lamina

    Article • Proceedings of the National Academy of Sciences, February 2019, Proceedings of the National Academy of Sciences

    Yang Liu

  22. Imaging Higher-order Chromatin Structures in Single Cells Using Stochastic Optical Reconstruction Microscopy

    Article • BIO-PROTOCOL, January 2019, Bio-Protocol, LLC

    Yang Liu

  23. ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB

    Article • Nature Communications, October 2018, Springer Science + Business Media

    Yang Liu

  24. Super-Resolution Imaging of Higher-Order Chromatin Structures at Different Epigenomic States in Single Mammalian Cells

    Article • Cell Reports, July 2018, Elsevier

    Yang Liu

  25. SIRT6 facilitates directional telomere movement upon oxidative damage

    Article • Scientific Reports, March 2018, Springer Science + Business Media

    Yang Liu

  26. Fourier phase based depth-resolved nanoscale nuclear architecture mapping for cancer detection

    Article • Methods, March 2018, Elsevier

    Yang Liu

  27. Stochastic Optical Reconstruction Microscopy (STORM)

    Article • Current Protocols in Cytometry, July 2017, Wiley

    Yang Liu

  28. SSRP1 Cooperates with PARP and XRCC1 to Facilitate Single-Strand DNA Break Repair by Chromatin Priming

    Article • Cancer Research, May 2017, American Association for Cancer Research (AACR)

    Yang Liu

  29. A simple and cost-effective setup for super-resolution localization microscopy

    Article • Scientific Reports, May 2017, Springer Science + Business Media

    Yang Liu

  30. A Simple Marker-Assisted 3D Nanometer Drift Correction Method for Superresolution Microscopy

    Article • Biophysical Journal, May 2017, Elsevier

    Yang Liu

  31. Quantitative phase imaging to improve the diagnostic accuracy of urine cytology

    Article • Cancer Cytopathology, May 2016, Wiley

    Yang Liu

  32. Early Prediction of Cancer Progression by Depth-Resolved Nanoscale Mapping of Nuclear Architecture from Unstained Tissue Specimens

    Article • Cancer Research, November 2015, American Association for Cancer Research (AACR)

    Yang Liu

  33. Fast and Precise 3D Fluorophore Localization based on Gradient Fitting

    Article • Scientific Reports, September 2015, Springer Science + Business Media

    Yang Liu

  34. Targeted DNA damage at individual telomeres disrupts their integrity and triggers cell death

    Article • Nucleic Acids Research, June 2015, Oxford University Press (OUP)

    Yang Liu

  35. Assessment of Nuclear Nanomorphology Marker to Improve the Detection of Malignancy From Bile Duct Biopsy Specimens

    Article • American Journal of Clinical Pathology, June 2014, Oxford University Press (OUP)

    Yang Liu

  36. Investigation of nanoscale structural alterations of cell nucleus as an early sign of cancer

    Article • BMC Biophysics, February 2014, Springer Science + Business Media

    Dr Sergey Alexandrov, Yang Liu

  37. Investigation of depth-resolved nanoscale structural changes in regulated cell proliferation and chromatin decondensation

    Article • Biomedical Optics Express, March 2013, Optical Society of America (OSA)

    Dr Sergey Alexandrov, Yang Liu

  38. Tomographic imaging via spectral encoding of spatial frequency

    Article • Optics Express, March 2013, Optical Society of America (OSA)

    Dr Sergey Alexandrov, Yang Liu

  39. Nuclear Nano-architecture Markers of Gastric Cardia and Upper Squamous Esophagus Detect Esophageal Cancer “Field Effect”

    Article • Journal of Cancer, January 2013, Ivyspring International Publisher

    Yang Liu

  40. Real-time quantitative visualization of 3D structural information

    Article • Optics Express, April 2012, Optical Society of America (OSA)

    Dr Sergey Alexandrov, Yang Liu

  41. Review of advanced imaging techniques

    Article • Journal of Pathology Informatics, January 2012, Elsevier

    Yang Liu

  42. Using optical markers of nondysplastic rectal epithelial cells to identify patients with ulcerative colitis-associated neoplasia

    Article • Inflammatory Bowel Diseases, December 2011, Oxford University Press (OUP)

    Yang Liu

  43. Spectral contrast imaging microscopy

    Article • Optics Letters, August 2011, Optical Society of America (OSA)

    Dr Sergey Alexandrov, Yang Liu

  44. Depth-selective fiber-optic probe for characterization of superficial tissue at a constant physical depth

    Article • Biomedical Optics Express, March 2011, Optical Society of America (OSA)

    Yang Liu

  45. Correction of stain variations in nuclear refractive index of clinical histology specimens

    Article • Journal of Biomedical Optics, January 2011, SPIE

    Yang Liu

  46. Quantification of nanoscale nuclear refractive index changes during the cell cycle

    Article • Journal of Biomedical Optics, January 2011, SPIE

    Yang Liu

  47. An insight into statistical refractive index properties of cell internal structure via low-coherence statistical amplitude microscopy

    Article • Optics Express, September 2010, Optical Society of America (OSA)

    Yang Liu

  48. Spatial-domain low-coherence quantitative phase microscopy for cancer diagnosis

    Article • Optics Letters, August 2010, Optical Society of America (OSA)

    Yang Liu

  49. Impact of Long-Wavelength UVA and Visible Light on Melanocompetent Skin

    Article • Journal of Investigative Dermatology, August 2010, Elsevier

    Yang Liu

  50. Nanoscale nuclear architecture for cancer diagnosis beyond pathology via spatial-domain low-coherence quantitative phase microscopy

    Article • Journal of Biomedical Optics, January 2010, SPIE

    Yang Liu

  51. Optical methodology for detecting histologically unapparent nanoscale consequences of genetic alterations in biological cells

    Article • Proceedings of the National Academy of Sciences, December 2008, Proceedings of the National Academy of Sciences

    Yang Liu

  52. Measuring mucosal blood supply in vivo with a polarization-gating probe

    Article • Applied Optics, November 2008, Optical Society of America (OSA)

    Yang Liu

  53. Optical Markers in Duodenal Mucosa Predict the Presence of Pancreatic Cancer

    Article • Clinical Cancer Research, August 2007, American Association for Cancer Research (AACR)

    Yang Liu

  54. Inducible nitric oxide synthase (iNOS) mediates the early increase of blood supply (EIBS) in colon carcinogenesis

    Article • FEBS Letters, July 2007, Wiley

    Yang Liu

  55. Penetration depth of low-coherence enhanced backscattered light in subdiffusion regime

    Article • Physical Review E, April 2007, American Physical Society (APS)

    Yang Liu

  56. Architecture and Performance of a Grid-Enabled Lookup-Based Biomedical Optimization Application: Light Scattering Spectroscopy

    Article • IEEE Transactions on Information Technology in Biomedicine, March 2007, Institute of Electrical & Electronics Engineers (IEEE)

    Yang Liu

  57. Spectroscopic translation of cell–material interactions

    Article • Biomaterials, January 2007, Elsevier

    Yang Liu

  58. FEASIBILITY OF USING BIOPHOTONICS TO ASSIST IN CYTOLOGIC DIAGNOSIS OF PANCREATIC CANCER

    Article • Pancreas, November 2006, Wolters Kluwer Health

    Yang Liu

  59. Engineering sub-100 nm multi-layer nanoshells

    Article • Nanotechnology, October 2006, Institute of Physics Publishing

    Yang Liu

  60. Circular polarization memory effect in low-coherence enhanced backscattering of light

    Article • Optics Letters, August 2006, Optical Society of America (OSA)

    Yang Liu

  61. Chemoprevention of colon carcinogenesis by polyethylene glycol: suppression of epithelial proliferation via modulation of SNAIL/β-catenin signaling

    Article • Molecular Cancer Therapeutics, August 2006, American Association for Cancer Research (AACR)

    Yang Liu

  62. Origin of low-coherence enhanced backscattering

    Article • Optics Letters, May 2006, Optical Society of America (OSA)

    Yang Liu

  63. Risk Stratification of Colon Carcinogenesis through Enhanced Backscattering Spectroscopy Analysis of the Uninvolved Colonic Mucosa

    Article • Clinical Cancer Research, February 2006, American Association for Cancer Research (AACR)

    Yang Liu

  64. Low-coherence enhanced backscattering: review of principles and applications for colon cancer screening

    Article • Journal of Biomedical Optics, January 2006, SPIE

    Yang Liu

  65. Optimal spectral reshaping for resolution improvement in optical coherence tomography

    Article • Optics Express, January 2006, Optical Society of America (OSA)

    Yang Liu

  66. Elastic backscattering spectroscopic microscopy

    Article • Optics Letters, September 2005, Optical Society of America (OSA)

    Yang Liu

  67. Spectral Markers in Preneoplastic Intestinal Mucosa: An Accurate Predictor of Tumor Risk in the MIN Mouse

    Article • Cancer Epidemiology Biomarkers & Prevention, July 2005, American Association for Cancer Research (AACR)

    Yang Liu

  68. Increased microvascular blood content is an early event in colon carcinogenesis

    Article • Gut, May 2005, BMJ

    Yang Liu

  69. Development of a bioengineered tissue model and its application in the investigation of the depth selectivity of polarization gating

    Article • Applied Optics, April 2005, Optical Society of America (OSA)

    Yang Liu

  70. Depth-resolved low-coherence enhanced backscattering

    Article • Optics Letters, April 2005, Optical Society of America (OSA)

    Yang Liu

  71. Low-coherent backscattering spectroscopy for tissue characterization

    Article • Applied Optics, January 2005, Optical Society of America (OSA)

    Yang Liu

  72. Investigation of depth selectivity of polarization gating for tissue characterization

    Article • Optics Express, January 2005, Optical Society of America (OSA)

    Yang Liu

  73. Optimal design of structured nanospheres for ultrasharp light-scattering resonances as molecular imaging multilabels

    Article • Journal of Biomedical Optics, January 2005, SPIE

    Yang Liu

  74. Coherent backscattering spectroscopy

    Article • Optics Letters, August 2004, Optical Society of America (OSA)

    Yang Liu

  75. Four-dimensional elastic light-scattering fingerprints as preneoplastic markers in the rat model of colon carcinogenesis☆

    Article • Gastroenterology, April 2004, Elsevier

    Yang Liu

  76. Simultaneous measurement of angular and spectral properties of light scattering for characterization of tissue microarchitecture and its alteration in early precancer

    Article • IEEE Journal of Selected Topics in Quantum Electronics, March 2003, Institute of Electrical & Electronics Engineers (IEEE)

    Yang Liu

  77. A detailed investigation into the oxidation mechanism of Hantzsch 1,4-dihydropyridines by ethyl α-cyanocinnamates and benzylidenemalononitriles

    Article • Journal of the Chemical Society Perkin Transactions 2, January 2000, Royal Society of Chemistry

    Yang Liu