All Stories

  1. Data from Body Weight Correlates with Molecular Variances in Patients with Cancer

    Article • March 2024, American Association for Cancer Research (AACR)

    Dr. Xinyang Zhao

  2. Data from Body Weight Correlates with Molecular Variances in Patients with Cancer

    Article • March 2024, American Association for Cancer Research (AACR)

    Dr. Xinyang Zhao

  3. Supplementary Data from Body Weight Correlates with Molecular Variances in Patients with Cancer

    Article • March 2024, American Association for Cancer Research (AACR)

    Dr. Xinyang Zhao

  4. Supplementary Data from Body Weight Correlates with Molecular Variances in Patients with Cancer

    Article • March 2024, American Association for Cancer Research (AACR)

    Dr. Xinyang Zhao

  5. Body Weight Correlates with Molecular Variances in Cancer Patients

    Article • Cancer Research, January 2024, American Association for Cancer Research (AACR)

    Dr. Xinyang Zhao

  6. Protein Arginine Methyltransferase 1 in the Generation of Immune Megakaryocytes: A Perspective Review

    Article • Journal of Biological Chemistry, September 2022, Elsevier

    Dr. Xinyang Zhao

  7. Metabolic Stress and Cardiovascular Disease in Diabetes Mellitus

    Article • Arteriosclerosis Thrombosis and Vascular Biology, October 2019, Wolters Kluwer Health

    Dr. Xinyang Zhao

  8. PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia

    Article • Blood, August 2019, American Society of Hematology

    Dr. Xinyang Zhao

  9. Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis

    Article • Journal of Neuro-Oncology, November 2018, Springer Science + Business Media

    Dr. Xinyang Zhao

  10. Defining the epigenetic status of blood cells using a cyanine-based fluorescent probe for PRMT1

    Article • Blood Advances, October 2018, American Society of Hematology

    Dr. Xinyang Zhao

  11. The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis inducing ligand

    Article • Journal of Biological Chemistry, May 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Xinyang Zhao

  12. The AS‐RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation

    Article • EMBO Reports, April 2016, EMBO

    Dr. Xinyang Zhao

  13. Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing

    Article • eLife, November 2015, eLife

    Dr. Xinyang Zhao

  14. Loss of RUNX1/AML1 arginine-methylation impairs peripheral T cell homeostasis

    Article • British Journal of Haematology, May 2015, Wiley

    Dr. Xinyang Zhao

  15. Exploration of Cyanine Compounds as Selective Inhibitors of Protein Arginine Methyltransferases: Synthesis and Biological Evaluation

    Article • Journal of Medicinal Chemistry, February 2015, American Chemical Society (ACS)

    Dr. Xinyang Zhao

  16. DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

    Article • Cell Reports, December 2014, Elsevier

    Dr. Xinyang Zhao, Altuna A

  17. Diamidine Compounds for Selective Inhibition of Protein Arginine Methyltransferase 1

    Article • Journal of Medicinal Chemistry, March 2014, American Chemical Society (ACS)

    Dr. Xinyang Zhao

  18. Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro

    Article • Journal of Neuro-Oncology, March 2014, Springer Science + Business Media

    Dr. Xinyang Zhao

  19. PRMT4 Blocks Myeloid Differentiation by Assembling a Methyl-RUNX1-Dependent Repressor Complex

    Article • Cell Reports, December 2013, Elsevier

    Dr. Xinyang Zhao

  20. Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

    Article • The Journal of Experimental Medicine, November 2013, Rockefeller University Press

    Dr. Xinyang Zhao

  21. Akt Phosphorylates the Transcriptional Repressor Bmi1 to Block Its Effects on the Tumor-Suppressing Ink4a-Arf Locus

    Article • Science Signaling, October 2012, American Association for the Advancement of Science

    Dr. Xinyang Zhao

  22. ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

    Article • Cancer Cell, August 2012, Elsevier

    Dr. Xinyang Zhao

  23. PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

    Article • Blood, April 2012, American Society of Hematology

    Dr. Xinyang Zhao

  24. The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

    Article • Blood, October 2011, American Society of Hematology

    Dr. Xinyang Zhao

  25. Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

    Article • Nature Methods, September 2011, Nature

    Dr. Xinyang Zhao

  26. The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

    Article • Science, July 2011, American Association for the Advancement of Science

    Dr. Xinyang Zhao

  27. Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

    Article • Cancer Cell, July 2011, Elsevier

    Dr. Xinyang Zhao

  28. The Mef/Elf4 Transcription Factor Fine Tunes the DNA Damage Response

    Article • Cancer Research, May 2011, American Association for Cancer Research (AACR)

    Dr. Xinyang Zhao

  29. JAK2V617F-Mediated Phosphorylation of PRMT5 Downregulates Its Methyltransferase Activity and Promotes Myeloproliferation

    Article • Cancer Cell, February 2011, Elsevier

    Dr. Xinyang Zhao

  30. Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera

    Article • Blood, June 2010, American Society of Hematology

    Dr. Xinyang Zhao

  31. Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

    Article • Genes & Development, March 2008, Cold Spring Harbor Laboratory Press

    Dr. Xinyang Zhao

  32. The Epidemiology of Hantavirus Infections

    Article • Clinical Microbiology Newsletter, April 1997, Elsevier

    Dr. Xinyang Zhao

  33. Figure 5—figure supplement 1. RBM15 binding to pre-mRNA of genes known important for hematopoiesis.

    Article • eLife

    Dr. Xinyang Zhao

  34. Figure 1—figure supplement 4. RBM15 methylation status is further confirmed by a methyl-RBM15 antibody.

    Article • eLife

    Dr. Xinyang Zhao

  35. Figure 4—figure supplement 2. RBM15 protein levels in MEG-01 cell lines expressing two short hairpin RNA constructs against RBM15 by western blots.

    Article • eLife

    Dr. Xinyang Zhao

  36. Figure 5—source data 1. Identification of RNAs associated with RBM15 by RNA immunoprecipitation assay with anti-RBM15 antibody.

    Article • eLife

    Dr. Xinyang Zhao

  37. Supplementary file 2. shRNA sequences for knocking down CNOT4 and RBM15 genes in human cells.

    Article • eLife

    Dr. Xinyang Zhao

  38. Figure 7—source data 1. Mass spectrometry analysis of RBM15-associated proteins.

    Article • eLife

    Dr. Xinyang Zhao

  39. Figure 6. Methylation of RBM15 controls alternative splicing of genes (RUNX1, GATA1 and c-MPL) important for MK differentiation.

    Article • eLife

    Dr. Xinyang Zhao

  40. Figure 3—figure supplement 1. Purified proteins used in vitro methylation and ubiquitylation assays.

    Article • eLife

    Dr. Xinyang Zhao