All Stories

  1. m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of Toxoplasma gondii

    Article • PLoS Pathogens, July 2021, PLOS

    Dr William J Sullivan

  2. Host sensing and signal transduction during Toxoplasma stage conversion

    Article • Molecular Microbiology, November 2020, Wiley

    Dr William J Sullivan

  3. Effects of PERK eIF2α Kinase Inhibitor against Toxoplasma gondii

    Article • Antimicrobial Agents and Chemotherapy, September 2018, ASM Journals

    Dr William J Sullivan

  4. Characterization of Plasmodium Atg3-Atg8 Interaction Inhibitors Identifies Novel Alternative Mechanisms of Action in Toxoplasma gondii

    Article • Antimicrobial Agents and Chemotherapy, November 2017, ASM Journals

    Joseph M Varberg, Dr William J Sullivan

  5. Toxoplasma gondii AP2IX-4 Regulates Gene Expression during Bradyzoite Development

    Article • mSphere, March 2017, ASM Journals

    Dr William J Sullivan

  6. TgPRELID, a Mitochondrial Protein Linked to Multidrug Resistance in the Parasite Toxoplasma gondii

    Article • mSphere, February 2017, ASM Journals

    Dr William J Sullivan, Joseph M Varberg

  7. Bromodomains in Protozoan Parasites: Evolution, Function, and Opportunities for Drug Development

    Article • Microbiology and Molecular Biology Reviews, January 2017, ASM Journals

    Dr William J Sullivan

  8. Garcinol Inhibits GCN5-Mediated Lysine Acetyltransferase Activity and Prevents Replication of the Parasite Toxoplasma gondii

    Article • Antimicrobial Agents and Chemotherapy, January 2016, ASM Journals

    Dr William J Sullivan

  9. TgATAT-Mediated α-Tubulin Acetylation Is Required for Division of the Protozoan Parasite Toxoplasma gondii

    Article • mSphere, January 2016, ASM Journals

    Dr William J Sullivan, Joseph M Varberg

  10. An ensemble of specifically targeted proteins stabilizes cortical microtubules in the human parasite Toxoplasma gondii

    Article • Molecular Biology of the Cell, December 2015, American Society for Cell Biology (ASCB)

    Dr William J Sullivan

  11. Guanabenz Repurposed as an Antiparasitic with Activity against Acute and Latent Toxoplasmosis

    Article • Antimicrobial Agents and Chemotherapy, August 2015, ASM Journals

    Dr William J Sullivan

  12. Proteome-Wide Lysine Acetylation in Cortical Astrocytes and Alterations That Occur during Infection with Brain Parasite Toxoplasma gondii

    Article • PLoS ONE, March 2015, PLOS

    Dr William J Sullivan

  13. How Toxoplasma Conquered the Animal Kingdom

    Article • Scientific American Mind, February 2015, Nature

    Dr William J Sullivan

  14. Canonical histone H2Ba and H2A.X dimerize in an opposite genomic localization to H2A.Z/H2B.Z dimers in Toxoplasma gondii

    Article • Molecular and Biochemical Parasitology, October 2014, Elsevier

    Dr William J Sullivan

  15. GCN2-like eIF2α kinase manages the amino acid starvation response in Toxoplasma gondii

    Article • International Journal for Parasitology, February 2014, Elsevier

    Dr William J Sullivan

  16. Lysine Acetyltransferase GCN5b Interacts with AP2 Factors and Is Required for Toxoplasma gondii Proliferation

    Article • PLoS Pathogens, January 2014, PLOS

    Dr William J Sullivan

  17. Epigenetic and Genetic Factors that Regulate Gene Expression in Toxoplasma gondii

    Article • January 2014, Elsevier

    Dr William J Sullivan

  18. Characterization of TgPuf1, a member of the Puf family RNA-binding proteins from Toxoplasma gondii

    Article • Parasites & Vectors, January 2014, Springer Science + Business Media

    Dr William J Sullivan

  19. The Histone Code of Toxoplasma gondii Comprises Conserved and Unique Posttranslational Modifications

    Article • mBio, December 2013, ASM Journals

    Dr William J Sullivan

  20. The Role of Host- and Parasite-Encoded Kinases inToxoplasma-Host Interactions

    Article • October 2013, Wiley

    Dr Ira J Blader, Dr William J Sullivan

  21. Elongator Protein 3 (Elp3) Lysine Acetyltransferase Is a Tail-anchored Mitochondrial Protein in Toxoplasma gondii

    Article • Journal of Biological Chemistry, July 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William J Sullivan

  22. The Unfolded Protein Response in the Protozoan Parasite Toxoplasma gondii Features Translational and Transcriptional Control

    Article • Eukaryotic Cell, May 2013, ASM Journals

    Dr William J Sullivan

  23. ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst

    Article • Proceedings of the National Academy of Sciences, April 2013, Proceedings of the National Academy of Sciences

    Dr William J Sullivan

  24. Inhibitors of eIF2α Dephosphorylation Slow Replication and Stabilize Latency in Toxoplasma gondii

    Article • Antimicrobial Agents and Chemotherapy, February 2013, ASM Journals

    Dr William J Sullivan

  25. Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii

    Article • Molecular BioSystems, January 2013, Royal Society of Chemistry

    Dr William J Sullivan

  26. Translational Control in Plasmodium and Toxoplasma Parasites

    Article • Eukaryotic Cell, December 2012, ASM Journals

    Dr William J Sullivan

  27. Toxoplasmahistone acetylation remodelers as novel drug targets

    Article • Expert Review of Anti-infective Therapy, October 2012, Taylor & Francis

    Dr William J Sullivan

  28. Mechanisms of Toxoplasma gondii persistence and latency

    Article • FEMS Microbiology Reviews, May 2012, Oxford University Press (OUP)

    Dr William J Sullivan

  29. Lysine Acetylation Is Widespread on Proteins of Diverse Function and Localization in the Protozoan Parasite Toxoplasma gondii

    Article • Eukaryotic Cell, April 2012, ASM Journals

    Dr William J Sullivan

  30. Toxoplasma gondii Sis1-like J-domain protein is a cytosolic chaperone associated to HSP90/HSP70 complex

    Article • International Journal of Biological Macromolecules, April 2012, Elsevier

    Dr William J Sullivan

  31. A GCN2-Like Eukaryotic Initiation Factor 2 Kinase Increases the Viability of Extracellular Toxoplasma gondii Parasites

    Article • Eukaryotic Cell, September 2011, ASM Journals

    Dr William J Sullivan

  32. Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondii

    Article • DNA Repair, May 2011, Elsevier

    Dr William J Sullivan

  33. Regions of intrinsic disorder help identify a novel nuclear localization signal in Toxoplasma gondii histone acetyltransferase TgGCN5-B

    Article • Molecular and Biochemical Parasitology, February 2011, Elsevier

    Dr William J Sullivan

  34. Toxoplasma gondii Lysine Acetyltransferase GCN5-A Functions in the Cellular Response to Alkaline Stress and Expression of Cyst Genes

    Article • PLoS Pathogens, December 2010, PLOS

    Dr William J Sullivan

  35. Phosphorylation of eukaryotic initiation factor-2α promotes the extracellular survival of obligate intracellular parasite Toxoplasma gondii

    Article • Proceedings of the National Academy of Sciences, September 2010, Proceedings of the National Academy of Sciences

    Dr William J Sullivan

  36. A decade of epigenetic research in Toxoplasma gondii

    Article • Molecular and Biochemical Parasitology, September 2010, Elsevier

    Dr William J Sullivan

  37. MYST Family Lysine Acetyltransferase Facilitates Ataxia Telangiectasia Mutated (ATM) Kinase-mediated DNA Damage Response in Toxoplasma gondii

    Article • Journal of Biological Chemistry, February 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William J Sullivan

  38. Toxoplasma H2A Variants Reveal Novel Insights into Nucleosome Composition and Functions for this Histone Family

    Article • Journal of Molecular Biology, September 2009, Elsevier

    Dr William J Sullivan

  39. Understanding mechanisms and the role of differentiation in pathogenesis of Toxoplasma gondii: a review

    Article • Memórias do Instituto Oswaldo Cruz, March 2009, FapUNIFESP (SciELO)

    Dr William J Sullivan

  40. The transcription of bradyzoite genes inToxoplasma gondiiis controlled by autonomous promoter elements

    Article • Molecular Microbiology, June 2008, Wiley

    Dr William J Sullivan

  41. Translation Regulation by Eukaryotic Initiation Factor-2 Kinases in the Development of Latent Cysts in Toxoplasma gondii

    Article • Journal of Biological Chemistry, April 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William J Sullivan

  42. Azurin-Like Protein Blocks Invasion of Toxoplasma gondii through Potential Interactions with Parasite Surface Antigen SAG1

    Article • Antimicrobial Agents and Chemotherapy, December 2007, ASM Journals

    Dr William J Sullivan

  43. Transport and Trafficking: Toxoplasma as a Model for Plasmodium

    Article • September 2007, Wiley

    Dr William J Sullivan

  44. Gene Regulation

    Article • January 2007, Elsevier

    Dr William J Sullivan

  45. Quinoline Derivative MC1626, a Putative GCN5 Histone Acetyltransferase (HAT) Inhibitor, Exhibits HAT-Independent Activity against Toxoplasma gondii

    Article • Antimicrobial Agents and Chemotherapy, December 2006, ASM Journals

    Dr William J Sullivan

  46. Histone mediated gene activation in Toxoplasma gondii

    Article • Molecular and Biochemical Parasitology, August 2006, Elsevier

    Dr William J Sullivan

  47. Pair of Unusual GCN5 Histone Acetyltransferases and ADA2 Homologues in the Protozoan Parasite Toxoplasma gondii

    Article • Eukaryotic Cell, January 2006, ASM Journals

    Dr William J Sullivan

  48. MYST Family Histone Acetyltransferases in the Protozoan Parasite Toxoplasma gondii

    Article • Eukaryotic Cell, December 2005, ASM Journals

    Professor Alan H Fairlamb, Dr William J Sullivan

  49. Histone-Modifying Complexes Regulate Gene Expression Pertinent to the Differentiation of the Protozoan Parasite Toxoplasma gondii

    Article • Molecular and Cellular Biology, December 2005, ASM Journals

    Dr William J Sullivan

  50. IMP Dehydrogenase from the Protozoan Parasite Toxoplasma gondii

    Article • Antimicrobial Agents and Chemotherapy, June 2005, ASM Journals

    Dr William J Sullivan

  51. Identification of proteins interacting with Toxoplasma SRCAP by yeast two-hybrid screening

    Article • Zeitschrift für Parasitenkunde Parasitology Research, January 2005, Springer Science + Business Media

    Dr William J Sullivan

  52. Histone Acetylase GCN5 Enters the Nucleus via Importin-  in Protozoan Parasite Toxoplasma gondii

    Article • Journal of Biological Chemistry, December 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William J Sullivan

  53. Purine Salvage Pathways in the Apicomplexan Parasite Toxoplasma gondii

    Article • Journal of Biological Chemistry, May 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William J Sullivan

  54. Histone H3 and H3.3 Variants in the Protozoan PathogensPlasmodium falciparumandToxoplasma gondii

    Article • DNA Sequence, June 2003, Taylor & Francis

    Dr William J Sullivan

  55. Cloning and characterization of a novel histone acetyltransferase homologue from the protozoan parasite Toxoplasma gondii reveals a distinct GCN5 family member

    Article • Gene, January 2000, Elsevier

    Dr William J Sullivan

  56. The Adenosine Transporter of Toxoplasma gondii: IDENTIFICATION BY INSERTIONAL MUTAGENESIS, CLONING, AND RECOMBINANT EXPRESSION

    Article • Journal of Biological Chemistry, December 1999, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William J Sullivan

  57. Recombinant expression, purification, and characterization of Toxoplasma gondii adenosine kinase

    Article • Molecular and Biochemical Parasitology, September 1999, Elsevier

    Dr William J Sullivan

  58. Insertional tagging of at least two loci associated with resistance to adenine arabinoside in Toxoplasma gondii, and cloning of the adenosine kinase locus

    Article • Molecular and Biochemical Parasitology, September 1999, Elsevier

    Dr William J Sullivan