All Stories

  1. BMP-2 Induced Expression of PLCβ1 That is a Positive Regulator of Osteoblast Differentiation

    Article • Journal of Cellular Physiology, November 2015, Wiley

    Dr William L Blalock

  2. Prohibitin 2: At a communications crossroads

    Article • IUBMB Life, April 2015, Wiley

    Dr William L Blalock, Dr William L Blalock

  3. PI-PLCβ1b affects Akt activation, cyclin E expression, and caspase cleavage, promoting cell survival in pro-B-lymphoblastic cells exposed to oxidative stress

    Article • The FASEB Journal, April 2015, Federation of American Societies For Experimental Biology (FASEB)

    Dr William L Blalock

  4. PLCβ1a and PLCβ1b Selective Regulation and Cyclin D3 Modulation Reduced by Kinamycin F During K562 Cell Differentiation

    Article • Journal of Cellular Physiology, November 2014, Wiley

    Dr William L Blalock, Dr William L Blalock

  5. Prohibitin 2 represents a novel nuclear AKT substrate during all-trans retinoic acid–induced differentiation of acute promyelocytic leukemia cells

    Article • The FASEB Journal, May 2014, Federation of American Societies For Experimental Biology (FASEB)

    Dr William L Blalock

  6. Identification of the PKR Nuclear Interactome Reveals Roles in Ribosome Biogenesis, mRNA Processing and Cell Division

    Article • Journal of Cellular Physiology, April 2014, Wiley

    Dr William L Blalock, Dr William L Blalock

  7. Nuclear PI-PLCβ1: An appraisal on targets and pathology

    Article • Advances in Biological Regulation, January 2014, Elsevier

    Dr William L Blalock, Dr William L Blalock

  8. EIF2AK2 (eukaryotic translation initiation factor 2-alpha kinase 2)

    Article • Atlas of Genetics and Cytogenetics in Oncology and Haematology, October 2012, INIST-CNRS

    Dr William L Blalock

  9. Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress

    Article • Leukemia, November 2010, Springer Science + Business Media

    Dr William L Blalock

  10. A role for PKR in hematologic malignancies

    Article • Journal of Cellular Physiology, January 2010, Wiley

    Dr William L Blalock, Dr William L Blalock

  11. PKR activity is required for acute leukemic cell maintenance and growth: A role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation

    Article • Journal of Cellular Physiology, October 2009, Wiley

    Dr William L Blalock, Dr William L Blalock

  12. A novel human fibronectin cryptic sequence unmasked by the insertion of the angiogenesis-associated extra type III domain B

    Article • International Journal of Cancer, August 2009, Wiley

    Dr William L Blalock, Dr William L Blalock

  13. RAX is required for fly neuronal development and mouse embryogenesis

    Article • Mechanisms of Development, September 2008, Elsevier

    Dr William L Blalock, Dr William L Blalock

  14. Proapoptotic Activity and Chemosensitizing Effect of the Novel Akt Inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-Cell Acute Lymphoblastic Leukemia

    Article • Molecular Pharmacology, June 2008, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr William L Blalock

  15. PKR is activated in MDS patients and its subcellular localization depends on disease severity

    Article • Leukemia, May 2008, Springer Science + Business Media

    Dr William L Blalock

  16. Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Module for Acute Myelogenous Leukemia Therapy: From Bench to Bedside

    Article • Current Medicinal Chemistry, August 2007, Bentham Science Publishers

    Dr William L Blalock

  17. PI-PLCβ-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes

    Article • Leukemia, July 2007, Springer Science + Business Media

    Dr William L Blalock

  18. Serine 18 Phosphorylation of RAX, the PKR Activator, Is Required for PKR Activation and Consequent Translation Inhibition

    Article • Journal of Biological Chemistry, August 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William L Blalock

  19. Ability of the Activated PI3K/Akt Oncoproteins to Synergize with MEK1 and Induce Cell Cycle Progression and Abrogate the Cytokine-Dependence of Hematopoietic Cells

    Article • Cell Cycle, April 2004, Taylor & Francis

    Dr William L Blalock, Dr William L Blalock

  20. Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention

    Article • Leukemia, June 2003, Springer Science + Business Media

    Dr William L Blalock

  21. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia

    Article • Leukemia, May 2003, Springer Science + Business Media

    Dr William L Blalock

  22. Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells

    Article • Oncogene, April 2003, Springer Science + Business Media

    Dr William L Blalock, Dr William L Blalock

  23. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy

    Article • Leukemia, March 2003, Springer Science + Business Media

    Dr William L Blalock

  24. Enhanced ability of the progenipoietin-1 to suppress apoptosis in human hematopoietic cells

    Article • International Journal of Molecular Medicine, October 2002, Spandidos Publications

    Dr William L Blalock

  25. Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf

    Article • Advances in Enzyme Regulation, May 2001, Elsevier

    Dr William L Blalock, Dr William L Blalock

  26. Ceramide Regulates Protein Synthesis by a Novel Mechanism Involving the Cellular PKR Activator RAX

    Article • Journal of Biological Chemistry, January 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr William L Blalock

  27. The Raf signal transduction cascade as a target for chemotherapeutic intervention in growth factor-responsive tumors

    Article • Pharmacology & Therapeutics, December 2000, Elsevier

    Dr William L Blalock, Dr William L Blalock

  28. Synergistic effects of akt on abrogation of cytokine-dependency induced by raf and mek

    Article • Experimental Hematology, July 2000, Elsevier

    Dr William L Blalock

  29. Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells

    Article • Advances in Enzyme Regulation, June 2000, Elsevier

    Dr William L Blalock, Dr William L Blalock

  30. A conditionally-active form of MEK1 results in autocrine transformation of human and mouse hematopoietic cells

    Article • Oncogene, January 2000, Springer Science + Business Media

    Dr William L Blalock, Dr William L Blalock

  31. Elucidation of Signal Transduction Pathways by Transfection of Cells with Modified Oncogenes

    Article • Springer Science + Business Media

    Dr William L Blalock, Dr William L Blalock

  32. Elucidation of Signal Transduction Pathways by Retroviral Infection of Cells with Modified Oncogenes

    Article • Springer Science + Business Media

    Dr William L Blalock, Dr William L Blalock

  33. Fibroblastic, Hematopoietic, and Hormone Responsive Epithelial Cell Lines and Culture Conditions for Elucidation of Signal Transduction and Drug Resistance Pathways by Gene Transfer

    Article • Springer Science + Business Media

    Dr William L Blalock, Dr William L Blalock