All Stories

  1. Liquid biopsy: An arsenal for tumour screening and early diagnosis

    Article • Cancer Treatment Reviews, September 2024, Elsevier

    Wen Zhang

  2. PD30-12 A PROSPECTIVE STUDY ON THE IMPACT OF CONTINUOUS SALINE BLADDER IRRIGATION AFTER TRANSURETHRAL RESECTION OF BLADDER TUMOR ON TUMOR CELL DISSEMINATION

    Article • The Journal of Urology, May 2024, Wolters Kluwer Health

    Wen Zhang

  3. Circulating tumor cell clustering modulates RNA splicing and polyadenylation to facilitate metastasis

    Article • Cancer Letters, April 2024, Elsevier

    Wen Zhang

  4. Predictive roles of NETs and IgG in neoadjuvant chemotherapy for muscle-invasive bladder cancer.

    Article • Journal of Clinical Oncology, February 2024, American Society of Clinical Oncology (ASCO)

    Wen Zhang

  5. Miniaturized Laser Probe for Exosome-Based Cancer Liquid Biopsy

    Article • Analytical Chemistry, January 2024, American Chemical Society (ACS)

    Wen Zhang

  6. Multi-Omics Analysis of Tislelizumab Plus Nab-Paclitaxel and Cisplatin as Neoadjuvant Immunochemotherapy for Locally Advanced Hypopharyngeal Squamous Cell Carcinoma: A Prospective Single-Arm Phase 2 Trial

    Article • January 2024, Elsevier

    Wen Zhang

  7. "Organoid Co-culture Models for Personalized Cancer Treatment"

    Article • Cancer Innovation, December 2023, Tsinghua University Press

    Wen Zhang

  8. Harnessing 3D in vitro systems to model immune responses to solid tumours: a step towards improving and creating personalized immunotherapies

    Article • Nature Reviews Immunology, July 2023, Springer Science + Business Media

    Wen Zhang

  9. Construction and validation of a chemokine family-based signature for the prediction of prognosis and therapeutic response in colon cancer

    Article • Heliyon, June 2023, Elsevier

    Wen Zhang

  10. Metastasis risk stratification and response prediction through dynamic viable circulating tumor cell counts for rectal cancer in a neoadjuvant setting

    Article • Cancer Medicine, April 2023, Wiley

    Wen Zhang

  11. Prognostic value of stem-like circulating tumor cells in patients with cancer: a systematic review and meta-analysis

    Article • Clinical and Experimental Medicine, February 2023, Springer Science + Business Media

    Wen Zhang

  12. Circulating tumour cell isolation, analysis and clinical application

    Article • Cellular Oncology, January 2023, Springer Science + Business Media

    Wen Zhang

  13. Microstructured Optical Fiber-Enhanced Light–Matter Interaction Enables Highly Sensitive Exosome-Based Liquid Biopsy of Breast Cancer

    Article • Analytical Chemistry, January 2023, American Chemical Society (ACS)

    Wen Zhang

  14. SIRPα antibody combined with oncolytic virus OH2 protects against tumours by activating innate immunity and reprogramming the tumour immune microenvironment

    Article • BMC Medicine, October 2022, Springer Science + Business Media

    Wen Zhang

  15. MA01.05 Immuno-microenvironment (TIME) Heterogeneity of Small Cell Lung Cancer (SCLC) Stratified by Molecular Subtypes

    Article • Journal of Thoracic Oncology, September 2022, Elsevier

    Wen Zhang

  16. Development and application of an uncapped mRNA platform

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Wen Zhang

  17. Telomerase positive CTCs with PSMA high expression associated with prostate cancer metastasis

    Article • Translational Andrology and Urology, June 2022, AME Publishing Company

    Wen Zhang

  18. Identification of Immune Subtypes of Lung Squamous Cell Carcinoma by Integrative Genome-Scale Analysis

    Article • Frontiers in Oncology, February 2022, Frontiers

    Wen Zhang

  19. Identification of an ACK1/TNK2-based prognostic signature for colon cancer to predict survival and inflammatory landscapes

    Article • BMC Cancer, January 2022, Springer Science + Business Media

    Wen Zhang

  20. Establishment of gastric signet ring cell carcinoma organoid for the therapeutic drug testing

    Article • Cell Death Discovery, January 2022, Springer Science + Business Media

    Wen Zhang

  21. Senescence as a dictator of patient outcomes and therapeutic efficacies in human gastric cancer

    Article • Cell Death Discovery, January 2022, Springer Science + Business Media

    Wen Zhang

  22. Single-cell transcriptomics of peripheral blood reveals anti-tumor systemic immunity induced by oncolytic virotherapy

    Article • Theranostics, January 2022, Ivyspring International Publisher

    Wen Zhang

  23. Improving the diagnosis of prostate cancer by telomerase-positive circulating tumor cells: A prospective pilot study

    Article • EClinicalMedicine, January 2022, Elsevier

    Wen Zhang

  24. Specific alternative splicing and polyadenylation facilitate metastasis mediated by CTC clusters

    Article • December 2021, Research Square

    Wen Zhang

  25. Senescence as a Dictator of Patient Outcomes and Therapeutic Efficacies in Human Gastric Cancer

    Article • December 2021, Research Square

    Wen Zhang

  26. Models based on nucleic acid methylation regulators will contribute to facilitating cancer precision medicine

    Article • BMC Medicine, December 2021, Springer Science + Business Media

    Wen Zhang

  27. Telomerase-positive circulating tumor cells are associated with poor prognosis via a neutrophil-mediated inflammatory immune environment in glioma

    Article • BMC Medicine, November 2021, Springer Science + Business Media

    Wen Zhang

  28. Combination of CT and telomerase-positive circulating tumor cells improves diagnosis of small pulmonary nodules

    Article • JCI Insight, April 2021, American Society for Clinical Investigation

    Wen Zhang

  29. Prospective Exploratory Study of the Clinical Significance of Circulating Tumor Cells in Patients With Small Cell Lung Cancer Exposed to Prophylactic Cranial Irradiation

    Article • Frontiers in Oncology, February 2021, Frontiers

    Wen Zhang

  30. Oncolytic Herpes Simplex Virus Type 2 Can Effectively Inhibit Colorectal Cancer Liver Metastasis by Modulating the Immune Status in the Tumor Microenvironment and Inducing Specific Antitumor Immunity

    Article • Human Gene Therapy, February 2021, Mary Ann Liebert Inc

    Wen Zhang

  31. Correlation between PD-L1 expression ON CTCs and prognosis of patients with cancer: a systematic review and meta-analysis

    Article • OncoImmunology, January 2021, Taylor & Francis

    Wen Zhang

  32. Telomerase Positive Circulating Tumor Cells Associated with Poor Prognosis <i>via</i> Neutrophil-Mediated Inflammatory Immune Environment in Glioma

    Article • SSRN Electronic Journal, January 2021, Elsevier

    Wen Zhang

  33. Characteristics, dynamic changes, and prognostic significance of TCR repertoire profiling in patients with renal cell carcinoma

    Article • The Journal of Pathology, March 2020, Wiley

    Liping Guo, Wen Zhang

  34. oHSV2 Can Target Murine Colon Carcinoma by Altering the Immune Status of the Tumor Microenvironment and Inducing Antitumor Immunity

    Article • Molecular Therapy — Oncolytics, March 2020, Elsevier

    Wen Zhang

  35. A CT-based radiomics nomogram for prediction of human epidermal growth factor receptor 2 status in patients with gastric cancer

    Article • Chinese Journal of Cancer Research, January 2020, Chinese Journal of Cancer Research

    Wen Zhang

  36. Evaluation of human epidermal growth factor receptor 2 status of breast cancer using preoperative multidetector computed tomography with deep learning and handcrafted radiomics features

    Article • Chinese Journal of Cancer Research, January 2020, Chinese Journal of Cancer Research

    Wen Zhang

  37. Enhanced Therapeutic Efficacy of a Novel Oncolytic Herpes Simplex Virus Type 2 Encoding an Antibody Against Programmed Cell Death 1

    Article • Molecular Therapy — Oncolytics, December 2019, Elsevier

    Wen Zhang

  38. Improved Stratification for Risk of Early Metastases by Baseline Circulating Tumor Cell Counts for Locally Advanced Rectal Cancer in Neoadjuvant Setting: an Exploratory Analysis from a Phase III trial

    Article • International Journal of Radiation Oncology*Biology*Physics, September 2019, Elsevier

    Wen Zhang

  39. Cooperation Between the Inflammation and Coagulation Systems Promotes the Survival of Circulating Tumor Cells in Renal Cell Carcinoma Patients

    Article • Frontiers in Oncology, June 2019, Frontiers

    Wen Zhang

  40. Preclinical Safety Evaluation of Oncolytic Herpes Simplex Virus Type 2

    Article • Human Gene Therapy, May 2019, Mary Ann Liebert Inc

    Wen Zhang

  41. A high-risk luminal A dominant breast cancer subtype with increased mobility

    Article • Breast Cancer Research and Treatment, February 2019, Springer Science + Business Media

    Wen Zhang

  42. Circulating tumor cells in the pulmonary vein increase significantly after lobectomy: A prospective observational study

    Article • Thoracic Cancer, December 2018, Wiley

    Wen Zhang

  43. Inhibition of colorectal cancer liver metastasis in BALB/c mice following intratumoral injection of oncolytic herpes simplex virus type 2 for the induction of specific antitumor immunity

    Article • Oncology Letters, November 2018, Spandidos Publications

    Wen Zhang

  44. Single nucleotide variant profiles of viable single circulating tumour cells reveal CTC behaviours in breast cancer

    Article • Oncology Reports, March 2018, Spandidos Publications

    Wen Zhang

  45. Detection of circulating tumor cells using oHSV1-hTERT-GFP in lung cancer

    Article • Thoracic Cancer, October 2017, Wiley

    Wen Zhang

  46. Tumor-selective replication herpes simplex virus-based technology significantly improves clinical detection and prognostication of viable circulating tumor cells

    Article • Oncotarget, May 2016, Impact Journals, LLC

    Wen Zhang

  47. Treatment of colon cancer with oncolytic herpes simplex virus in preclinical models

    Article • Gene Therapy, February 2016, Springer Science + Business Media

    Wen Zhang

  48. A novel oHSV-1 targeting telomerase reverse transcriptase-positive cancer cells via tumor-specific promoters regulating the expression of ICP4

    Article • Oncotarget, May 2015, Impact Journals, LLC

    Wen Zhang

  49. A Novel Oncolytic Herpes Simplex Virus Type 2 Has Potent Anti-Tumor Activity

    Article • PLoS ONE, March 2014, PLOS

    Wen Zhang

  50. Doxorubicin-enriched, ALDHbr mouse breast cancer stem cells are treatable to oncolytic herpes simplex virus type 1

    Article • BMC Cancer, November 2012, Springer Science + Business Media

    Wen Zhang

  51. Calcineurin stimulates the expression of inflammatory factors in RAW 264.7 cells by interacting with proteasome subunit alpha type 6

    Article • Biochemical and Biophysical Research Communications, April 2011, Elsevier

    Wen Zhang

  52. Calcineurin B subunit interacts with proteasome subunit alpha type 7 and represses hypoxia-inducible factor-1α activity via the proteasome pathway

    Article • Biochemical and Biophysical Research Communications, February 2011, Elsevier

    Wen Zhang

  53. Infusion of FK506, a specific inhibitor of calcineurin, induces potent tau hyperphosphorylation in mouse brain

    Article • Brain Research Bulletin, July 2008, Elsevier

    Wen Zhang

  54. Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain

    Article • IUBMB Life, July 2006, Wiley

    Wen Zhang