All Stories

  1. In vitro response of human ovarian cancer cells to dietary bioflavonoid isoquercitrin
  2. Isolated Silymarin Flavonoids Increase Systemic and Hepatic Bilirubin Concentrations and Lower Lipoperoxidation in Mice
  3. In-Cell Biochemistry Using NMR Spectroscopy
  4. Enzymatic oxidative dimerization of silymarin flavonolignans
  5. Access to bifunctionalized biomolecular platforms using oxime ligation
  6. Dehydro-flavonolignans from silymarin are potent inhibitors of lipid peroxidation in isolated respiring rat heart and liver mitochondria
  7. Isoquercitrin: Pharmacology, toxicology, and metabolism
  8. cis – trans Isomerization of silybins A and B
  9. Chemo-Enzymatic Synthesis of Silybin and 2,3-Dehydrosilybin Dimers
  10. Preparation of silybin phase II metabolites: Streptomyces catalyzed glucuronidation
  11. Inhibition of GlcNAc-Processing Glycosidases by C-6-Azido-NAG-Thiazoline and Its Derivatives
  12. Expression, characterization and homology modeling of a novel eukaryotic GH84 β-N-acetylglucosaminidase from Penicillium chrysogenum
  13. Biphasic Catalysis with Disaccharide Phosphorylases: Chemoenzymatic Synthesis of α-d-Glucosides Using Sucrose Phosphorylase
  14. Re-Evaluation of Binding Properties of Recombinant Lymphocyte Receptors NKR-P1A and CD69 to Chemically Synthesized Glycans and Peptides
  15. Chemistry of silybin
  16. Biotransformation of Silybin and its Congeners
  17. LC–MS metabolic study on quercetin and taxifolin galloyl esters using human hepatocytes as toxicity and biotransformation in vitro cell model
  18. Recombinant α-L-rhamnosidase ofAspergillus terreusimmobilization in polyvinylalcohol hydrogel and its application in rutin derhamnosylation
  19. Chemoenzymatic synthesis of α-l-rhamnosides using recombinant α-l-rhamnosidase from Aspergillus terreus
  20. Antioxidant, metal-binding and DNA-damaging properties of flavonolignans: A joint experimental and computational highlight based on 7-O-galloylsilybin
  21. Preparative Purification and Isolation of Pyranoanthocyanins from Red Wine and Evaluation of Their Antioxidant Activity
  22. ChemInform Abstract: Enzymatic Glycosylation of Multivalent Scaffolds
  23. Effect of 3-O-Galloyl Substitution on the Electrochemical Oxidation of Quercetin and Silybin Galloyl Esters at Glassy Carbon Electrode
  24. Preparation of silybin and isosilybin sulfates by sulfotransferase from Desulfitobacterium hafniense
  25. Bioavailability of silymarin flavonolignans: drug formulations and biotransformation
  26. Anti-Cancer Efficacy of Silybin Derivatives - A Structure-Activity Relationship
  27. Enzymatic preparation of silybin phase II metabolites: sulfation using aryl sulfotransferase from rat liver
  28. Enzymatic synthesis of new C-6-acylated derivatives of NAG-thiazoline and evaluation of their inhibitor activities towards fungal β-N-acetylhexosaminidase
  29. A Novel Semisynthetic Flavonoid 7-O-Galloyltaxifolin Upregulates Heme Oxygenase-1 in RAW264.7 Cells via MAPK/Nrf2 Pathway
  30. ChemInform Abstract: Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts
  31. Enzymatic glycosylation of multivalent scaffolds
  32. β‐N‐Acetylhexosaminidases: group‐specific inhibitors wanted
  33. Preparative method for isosilybin isolation based on enzymatic kinetic resolution of silymarin mixture
  34. Ionic liquids as cosolvents for glycosylation by sucrose phosphorylase: balancing acceptor solubility and enzyme stability
  35. Base-catalyzed oxidation of silybin and isosilybin into 2,3-dehydro derivatives
  36. Production of Aspergillus niger β-mannosidase in Pichia pastoris
  37. Enzymatic Glycosylation of Small Molecules: Challenging Substrates Require Tailored Catalysts
  38. Preparatory production of quercetin-3-β-d-glucopyranoside using alkali-tolerant thermostable α-l-rhamnosidase from Aspergillus terreus
  39. Biotransformation of flavonols and taxifolin in hepatocyte in vitro systems as determined by liquid chromatography with various stationary phases and electrospray ionization-quadrupole time-of-flight mass spectrometry
  40. Chemo-enzymatic modification of poly- N -acetyllactosamine (LacNAc) oligomers and N,N -diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment
  41. Recombinant α-l-rhamnosidase from Aspergillus terreus in selective trimming of rutin
  42. Facile synthesis of nitrophenyl 2-acetamido-2-deoxy-α-D-mannopyranosides from ManNAc-oxazoline
  43. Quercetin, Quercetin Glycosides and Taxifolin Differ in their Ability to Induce AhR Activation and CYP1A1 Expression in HepG2 Cells
  44. Heterologous Expression and Characterization of an N-Acetyl-β-d-hexosaminidase from Lactococcus lactis ssp. lactis IL1403
  45. Sequencing, cloning and high-yield expression of a fungal β-N-acetylhexosaminidase in Pichia pastoris
  46. Facile production of Aspergillus niger α-N-acetylgalactosaminidase in yeast
  47. Flavonoid-dependent Attenuation of Mitochondrial ROS Formation is Augmented by Their Modulation of Bioenergetic Status of the Cell
  48. Synthesis and Antiangiogenic Activity of New Silybin Galloyl Esters
  49. Electrochemical investigation of flavonolignans and study of their interactions with DNA in the presence of Cu(II)
  50. Laboratory evolution of an epoxide hydrolase – Towards an enantioconvergent biocatalyst
  51. Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products
  52. ChemInform Abstract: Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short
  53. Purification and characterization of heterologously expressed nitrilases from filamentous fungi
  54. Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir-Glycosyltransferases
  55. Regioselective alcoholysis of silybin A and B acetates with lipases
  56. Charged Hexosaminides as New Substrates for β-N-Acetylhexosaminidase-Catalyzed Synthesis of Immunomodulatory Disaccharides
  57. Study of electrooxidation mechanisms and antioxidant properties of flavonols and flavonolignans
  58. Narrow-bore core-shell particles and monolithic columns in the analysis of silybin diastereoisomers
  59. Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β‐N‐acetylhexosaminidase
  60. Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases
  61. Dimerisation Process of Silybin-Type Flavonolignans: Insights from Theory
  62. Glycosidases in Carbohydrate Synthesis: When Organic Chemistry Falls Short
  63. Dendri-RAFTs: a second generation of cyclopeptide-based glycoclusters
  64. Dehydrosilybin attenuates the production of ROS in rat cardiomyocyte mitochondria with an uncoupler-like mechanism
  65. Analysis of anthocyanin pigments in Lonicera (Caerulea) extracts using chromatographic fractionation followed by microcolumn liquid chromatography-mass spectrometry
  66. β-N-Acetylhexosaminidase: What's in a name…?
  67. Large-scale separation of silybin diastereoisomers using lipases
  68. Genome mining for the discovery of new nitrilases in filamentous fungi
  69. Azido leaving group in enzymatic synthesis-small and efficient
  70. Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles
  71. Cardioprotective activity of dehydrosilybin is linked to its uncoupler-like behavior
  72. Effect of flavonolignans derived from silybin on mitochondrial production of reactive oxygen species
  73. ChemInform Abstract: Enzymatic Glycosylation of Branched Symmetrical Non-Carbohydrate Polyols.
  74. ChemInform Abstract: Enzymatic Synthesis of p-Nitrophenyl β-Chitobioside.
  75. ChemInform Abstract: Enzymatic Glycosylation Using 6-O-Acylated Sugar Donors and Acceptors: β-N-Acetylhexosaminidase-Catalyzed Synthesis of 6-O,N,N′-Triacetylchitobiose (III) and 6′-O,N,N′-Triacetylchitobiose (VI).
  76. ChemInform Abstract: Selective Biotransformation of Substituted Alicyclic Nitriles by Rhodococcus equi A4.
  77. Biotransformations with nitrilases
  78. Antioxidant and antiviral activities of silybin fatty acid conjugates
  79. ChemInform Abstract: Glycosidases in Synthesis
  80. Enzymatic Processing of Bioactive Glycosides from Natural Sources
  81. Condensation reactions catalyzed by α-N-acetylgalactosaminidase fromAspergillus nigeryielding α-N-acetylgalactosaminides
  82. Silybin Derivatives Modulate Thyroid Hormone-Mediated UcP2 Expression in Neonatal Rat Cardiomyocytes
  83. Chemoenzymatic preparative separation of silybins A and B
  84. Silybin (Silibinin) Structure and Chirality
  85. Fungal nitrilases as biocatalysts: Recent developments
  86. Glycosidases: a key to tailored carbohydrates
  87. Silibinin chirality
  88. Molecular mechanisms of silybin and 2,3-dehydrosilybin antiradical activity—role of individual hydroxyl groups
  89. α-Galactosidases and their applications in biotransformations
  90. Enzymatic preparation of acylated derivatives of silybin in organic and ionic liquid media and evaluation of their antitumor proliferative activity
  91. Biodegradation potential of the genus Rhodococcus
  92. Chemo-enzymatic synthesis of poly-N-acetyllactosamine (poly-LacNAc) structures and their characterization for CGL2-galectin-mediated binding of ECM glycoproteins to biomaterial surfaces
  93. Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: In vivo safety assessment
  94. Selection and screening for enzymes of nitrile metabolism
  95. Laccase-mediated dimerization of the flavonolignan silybin
  96. Biotransformation of nitriles to amides using soluble and immobilized nitrile hydratase from Rhodococcus erythropolis A4
  97. Mechanism of the Antioxidant Action of Silybin and 2,3-Dehydrosilybin Flavonolignans: A Joint Experimental and Theoretical Study
  98. Glycoside vs. Aglycon: The Role of Glycosidic Residue in Biological Activity
  99. Studies on oxidation of ergot alkaloids: oxidation and desaturation of dihydrolysergol—stereochemical requirements
  100. Structure, Function and Dynamics of fungal β-N-Hexosaminidase
  101. Structural modeling of alpha-galactosidase and alpha-galactosaminidase from Aspergillus Niger
  102. New aldoxime-dehydrating enzymes from filamentous fungi
  103. Glycosyl Azides – An Alternative Way to Disaccharides
  104. Structure of the dimeric N-glycosylated form of fungal β-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies
  105. Biotransformation of heterocyclic dinitriles by Rhodococcus erythropolis and fungal nitrilases
  106. Large Propeptides of Fungal β-N-Acetylhexosaminidases Are Novel Enzyme Regulators That Must Be Intracellularly Processed to Control Activity, Dimerization, and Secretion into the Extracellular Environment
  107. Silybin and Silymarin - New and Emerging Applications in Medicine
  108. Induction and characterization of an unusual α-d-galactosidase from Talaromyces flavus
  109. Extension of the Nef reaction to C-glycosylnitromethanes
  110. Cyanodeoxy-Glycosyl Derivatives as Substrates for Enzymatic Reactions
  111. Preparative production and separation of 2-acetamido-2-deoxymannopyranoside-containing saccharides using borate-saturated polyolic exclusion gels
  112. New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity
  113. Unique transglycosylation potential of extracellular α-d-galactosidase from Talaromyces flavus
  114. β-1,4-Galactosyltransferase-catalyzed glycosylation of sugar derivatives: Modulation of the enzyme activity by α-lactalbumin, immobilization and solvent tolerance
  115. Cyanodeoxy‐Glycosyl Derivatives as Substrates for Enzymatic Reactions
  116. Immobilization of fungal nitrilase and bacterial amidase – two enzymes working in accord
  117. Glycosyl azide—a novel substrate for enzymatic transglycosylations
  118. Effects of silymarin flavonolignans and synthetic silybin derivatives on estrogen and aryl hydrocarbon receptor activation
  119. Silybin and silymarin - new effects and applications
  120. The efficacy of glucosamine and chondroitin sulfate in the treatment of osteoarthritis: are these saccharides drugs or nutraceuticals?
  121. Biocatalyzed Generation of Molecular Diversity: Selective Modification of the Saponin Asiaticoside
  122. Combined Application of Galactose Oxidase and β-N-Acetylhexosaminidase in the Synthesis of Complex ImmunoactiveN-Acetyl-D-galactosaminides
  123. A chemoenzymatic route to mannosamine derivatives bearing different N-acyl groups
  124. Screening and characterization of β-N-acetylhexosaminidases for the synthesis of nucleotide-activated disaccharides
  125. Synthesis of 4-Nitrophenyl 2-Acetamido-2-deoxy-β-D-mannopyranoside and 4-Nitrophenyl 2-Acetamido-2-deoxy-α-D-mannopyranoside.
  126. Enzymatic Discrimination of 2-Acetamido-2-deoxy-D-mannopyranose-Containing Disaccharides Using β-N-Acetylhexosaminidases
  127. Chemical Biology and Biomedicine of Glycosylated Natural Compounds
  128. Synthesis of 4-Nitrophenyl 2-Acetamido-2-deoxy-β-D-mannopyranoside and 4-Nitrophenyl 2-Acetamido-2-deoxy-α-D-mannopyranoside
  129. Selective biotransformation of substituted alicyclic nitriles by Rhodococcus equi A4
  130. p-NITROPHENYL 2-AZIDO-2-DEOXY-D-HEXOPYRANOSIDES AS DONORS FOR ENZYMIC GLYCOSYLATION
  131. Nitrile- and Amide-converting Microbial Enzymes: Stereo-, Regio- and Chemoselectivity
  132. Exploitation of a library of ?-galactosidases for the synthesis of building blocks for glycopolymers
  133. Glycosides in Medicine: “The Role of Glycosidic Residue in Biological Activity”
  134. Chemical Biology and Biomedicine of Glycosylated Natural Compounds
  135. Semisynthetic Dimers of Antiparkinsonic Ergot Alkaloids
  136. Enzymatic Glycosylation of Lincomycin
  137. Silymarin: What is in the name…? An appeal for a change of editorial policy
  138. ChemInform Abstract: Enzymatic Preparation of Lysergol β‐D‐Glucuronide.
  139. ChemInform Abstract: One‐pot Enzymatic Synthesis of Sialyl T‐Epitope
  140. Formation ofmyo-inositol phosphates byAspergillus niger 3-phytase
  141. ChemInform Abstract: Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases.
  142. Enzymatic Preparation of Lysergol β-D-Glucuronide
  143. Enzymatic synthesis of iso-globotriose from partially protected lactose
  144. Agroclavine Glycosylation
  145. One-Pot Enzymatic Synthesis of Sialyl T-Epitope
  146. Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases
  147. Enzymatic Synthesis ofP-Nitrophenyl β-Chitobioside
  148. Unusual nonreducing sugar GlcNAcβ(1↔1)Manβ formation by β-N-acetylhexosaminidase from Aspergillus oryzae
  149. Enzymatic Glycosylation of Branched Symmetrical Non-Carbohydrate Polyols
  150. Glycosidase-Catalysed Synthesis of Ergot Alkaloid α-Glycosides
  151. Effect ofp-Substitution of Aryl α-D-Mannosides on Inhibiting Mannose-Sensitive Adhesion ofEscherichia coli – Syntheses and Testing
  152. Glucosylation of silybin by plant cell cultures of Papaver somniferum var. setigerum
  153. Transglycosylation of Thiamin by Fungal β-N-Acetylhexosaminidases
  154. β-Glucosylation of chitooligomers by galactosyltransferase
  155. Biotransformation of Ergot Alkaloids by Haloperoxidase fromStreptomyces aureofaciens: Stereoselective Acetoxylation and Propionoxylation
  156. N -Deoxyribosides of ergot alkaloids: Synthesis and biological activity
  157. Enzymatic and chemical glycosylations of ergot alkaloids and biological aspects of new compounds
  158. Synthesis and Antiviral Evaluation of N-β-D-Ribosides of Ergot Alkaloids
  159. Glycosylation of silybin
  160. Sterols and fatty acids in Peziza muralis
  161. Ergot alkaloid glycosides with immunomodulatory activities
  162. Biotransformations of γ-methyl-β-ketosulfones: stereoselectivity of 3-methyl-1-(phenylsulfonyl)hexan-2-one reductions by various yeasts
  163. N-1-Trimethylsilyl Derivatives of Ergot Alkaloids
  164. Biotransformation of Chanoclavine by Euphorbia calyptrata Cell Culture
  165. Dimerization of Lysergene by Euphorbia calyptrata Cell Cultures
  166. Biotransformations of aromatic diniitriles using Rhodococcus equi cells
  167. A Multienzyme System for a One-Pot Synthesis of Sialyl T-Antigen
  168. Ein Multienzymsystem zur Eintopfsynthese des Sialyl‐T‐Antigens
  169. Assignment of Nitrogen Stereochemistry of Agroclavine and Elymoclavine 6-N-Oxides
  170. Synthesis of α-mannosylated ergot alkaloids employing α-mannosidase
  171. Fast atom bombardment mass spectrometry of elymoclavine glycosides
  172. Claviceps purpurea (Ergot): Culture and Bioproduction of Ergot Alkaloids
  173. Determination of Lovastatin (mevinolin) and mevinolinic acid in fermentation liquids
  174. Fructosylation of ergot alkaloids by yeast invertase
  175. Galactose oxidase production by immobilized cells ofDactylium dendroides
  176. Bioconversions of ergot alkaloids
  177. Glycosylation of ergot alkaloids by free and immobilized cells of Claviceps purpurea
  178. Effect of triadimefon on lipids, sterols, and membrane fluidity in submerged cultures of claviceps purpurea
  179. Physiological control and process kinetics of clavine alkaloid production byClaviceps purpurea
  180. Physiological control and process kinetics of clavine alkaloid production byClaviceps purpurea
  181. Effect of clomiphene on fatty acids, sterols and membrane fluidity in clavine producing claviceps purpurea strains
  182. Physiological activity of immobilized cells of Claviceps fusiformis during long-term semicontinuous cultivation
  183. Effect of cultivation temperature, clomiphene, and nystatin on the oxidation and cyclization of chanoclavine in submerged cultures of the mutant strainclaviceps purpurea 59
  184. High-production mutant Claviceps purpurea 59 accumulating secoclavines
  185. Identification of fatty acids in submerged cultures of Claviceps species
  186. Occurrence of ricinoleic acid in submerged cultures of variousClaviceps sp.
  187. Continuous cultivation ofCandida utilis yeasts growing on calcium bisulphite waste liquors
  188. Glycosidases in synthesis