All Stories

  1. Comparative Analysis of Orthosteric and Allosteric GLP-1R Agonists’ Effects on Insulin Secretion from Healthy, Diabetic, and Recovered INS-1E Pancreatic Beta Cells
  2. The Regulation of Metabolic Homeostasis by Incretins and the Metabolic Hormones Produced by Pancreatic Islets
  3. Correction: Jannoo et al. Targeting and Sensitization of Breast Cancer Cells to Killing with a Novel Interleukin-13 Receptor α2-Specific Hybrid Cytolytic Peptide. Cancers 2023, 15, 2772
  4. The Evolution and Complications of Long-Term Mechanical Circulatory Support Devices
  5. Frontline clinical diagnosis—FTIR on pancreatic cancer
  6. Targeting and Sensitization of Breast Cancer Cells to Killing with a Novel Interleukin-13 Receptor α2-Specific Hybrid Cytolytic Peptide
  7. Molecular Analysis of SARS-CoV-2 Spike Protein-Induced Endothelial Cell Permeability and vWF Secretion
  8. Targeting of the Interleukin-13 Receptor (IL-13R)α2 Expressing Prostate Cancer by a Novel Hybrid Lytic Peptide
  9. ADP-ribosylation factor 6 expression increase in oesophageal adenocarcinoma suggests a potential biomarker role for it
  10. A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives
  11. Hemodilution Increases the Susceptibility of Red Blood Cells to Mechanical Shear Stress During In Vitro Hemolysis Testing
  12. Discussing recent advances and perspectives in GLP-1 based therapies for type 2 diabetes treatment
  13. Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability
  14. Mechanism of cardiovascular disease benefit of glucagon-like peptide 1 agonists
  15. ADAP2
  16. EFA6 regulates selective polarised transport and axon regeneration from the axon initial segment
  17. The Bacterial Species Campylobacter jejuni Induce Diverse Innate Immune Responses in Human and Avian Intestinal Epithelial Cells
  18. Shear Stress-Induced Total Blood Trauma in Multiple Species
  19. Signal transducer and activator of transcription-3 licenses Toll-like receptor 4-dependent interleukin (IL)-6 and IL-8 production via IL-6 receptor-positive feedback in endometrial cells
  20. Luteinizing hormone/chorionic gonadotrophin receptor overexpressed in granulosa cells from polycystic ovary syndrome ovaries is functionally active
  21. Molecular Characterisation of Small Molecule Agonists Effect on the Human Glucagon Like Peptide-1 Receptor Internalisation
  22. Distinct regions in the C-Terminus required for GLP-1R cell surface expression, activity and internalisation
  23. Exclusion of Integrins from CNS Axons Is Regulated by Arf6 Activation and the AIS
  24. Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor
  25. Agonist-induced internalisation of the glucagon-like peptide-1 receptor is mediated by the Gαq pathway
  26. The regions within the N-terminus critical for human glucagon like peptide-1 receptor (hGLP-1R) cell Surface expression
  27. Cytohesin 2/ARF6 regulates preadipocyte migration through the activation of ERK1/2
  28. Exchange Factor EFA6R Requires C-terminal Targeting to the Plasma Membrane to Promote Cytoskeletal Rearrangement through the Activation of ADP-ribosylation Factor 6 (ARF6)
  29. The temporal expression of estrogen receptor alpha-36 and runx2 in human bone marrow derived stromal cells during osteogenesis
  30. The Effect of Shear Stress on the Size, Structure, and Function of Human von Willebrand Factor
  31. ADP-ribosylation factor 6 regulates endothelin-1-induced lipolysis in adipocytes
  32. Lactoferrin inhibits dexamethasone-induced chondrocyte impairment from osteoarthritic cartilage through up-regulation of extracellular signal-regulated kinase 1/2 and suppression of FASL, FAS, and Caspase 3
  33. ARF6-Dependent Regulation of P2Y Receptor Traffic and Function in Human Platelets
  34. ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons
  35. ARF6 Activated by the LHCG Receptor through the Cytohesin Family of Guanine Nucleotide Exchange Factors Mediates the Receptor Internalization and Signaling
  36. ADP-Ribosylation Factor 6 Expression and Activation Are Reduced in Myometrium in Complicated Pregnancies
  37. A balanced chromosomal translocation disruptingARHGEF9is associated with epilepsy, anxiety, aggression, and mental retardation
  38. Single-Channel Characterization of the Rabbit Recombinant RyR2 Reveals a Novel Inactivation Property of Physiological Concentrations of ATP
  39. The calcium-sensing receptor changes cell shape via a β-arrestin-1–ARNO–ARF6–ELMO protein network
  40. PI-3-kinase-dependent membrane recruitment of centaurin-α2 is essential for its effect on ARF6-mediated actin cytoskeleton reorganisation
  41. Alternative splicing generates a smaller assortment of CaV2.1 transcripts in cerebellar Purkinje cells than in the cerebellum
  42. Centaurin-α1 and KIF13B kinesin motor protein interaction in ARF6 signalling
  43. A novel 4.1 ezrin radixin moesin (FERM)‐containing protein, ‘Willin’
  44. Centaurin-α1 interacts directly with kinesin motor protein KIF13B
  45. Centaurin-α1, an ADP-Ribosylation Factor 6 GTPase Activating Protein, Inhibits β2-Adrenoceptor Internalization
  46. Analysis of the Interaction Between Cytohesin 2 and IPCEF1
  47. Centaurin-α1 Is an in Vivo Phosphatidylinositol 3,4,5-Trisphosphate-dependent GTPase-activating Protein for ARF6 That Is Involved in Actin Cytoskeleton Organization
  48. Interaction Protein for Cytohesin Exchange Factors 1 (IPCEF1) Binds Cytohesin 2 and Modifies Its Activity
  49. Functional coupling of rat metabotropic glutamate 1a receptors to phospholipase D in CHO cells: involvement of extracellular Ca2+, protein kinase C, tyrosine kinase and Rho-A
  50. Human Sterol 14α-Demethylase Activity Is Enhanced by the Membrane-Bound State of Cytochrome b5
  51. Activities and Kinetic Mechanisms of Native and Soluble NADPH–Cytochrome P450 Reductase
  52. Casein Kinase I Associates with Members of the Centaurin-α Family of Phosphatidylinositol 3,4,5-Trisphosphate-binding Proteins
  53. Phosphatidylinositol 3-kinase–dependent translocation of phospholipase Cγ2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation
  54. Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase
  55. Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes
  56. Molecular Cloning and Functional Characterization of a Human Homologue of Centaurin-α
  57. Generation of a Complete, Soluble, and Catalytically Active Sterol 14α-Demethylase−Reductase Complex
  58. Identification of centaurin-α1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1
  59. Identification of the Ras GTPase-activating protein GAP1m as a phosphatidylinositol-3,4,5-trisphosphate-binding protein in vivo
  60. Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase
  61. The N-Terminal Membrane Domain of Yeast NADPH-Cytochrome P450 (CYP) Oxidoreductase Is Not Required for Catalytic Activity in Sterol Biosynthesis or in Reconstitution of CYP Activity
  62. Distinct subcellular localisations of the putative inositol 1,3,4,5-tetrakisphosphate receptors GAP1 IP4BP and GAP1 m result from the GAP1 IP4BP PH domain directing plasma membrane targeting
  63. In-vitro activity of D0870, a new triazole antifungal drug, in comparison with fluconazole and itraconazole against Aspergillus fumigatus and Candida krusei
  64. Stereoselective interaction of SCH 39304, a triazole, with sterol 14alpha-demethylase of Aspergillus fumigatus
  65. Biochemical characterisation of ketoconazole inhibitory action onAspergillus fumigatus
  66. Investigation of Cytochrome P450 Mediated Benzo(a)pyrene Hydroxylation in Aspergillus fumigatus
  67. Evidence for cytochrome P-450 and P-450-mediated benzo(a) pyrene hydroxylation in the white rot fungusPhanerochaete chrysosporium
  68. Resistance to fluconazole in Candida albicans from AIDS patients correlated with reduced intracellular accumulation of drug
  69. Microsomal and cytosolic cytochrome P450 mediated benzo(a)pyrene hydroxylation in Pleurotus pulmonarius
  70. Studies on yeast host strains for heterologous P450 expression
  71. Ammonium represses NADPH-nitrate reductase in the moss Funaria hygrometrica