All Stories

  1. The crystal structure of the N-terminal domain of the backbone pilin LrpA reveals a new closure-and-twist motion for assembling dynamic pili in Ligilactobacillus ruminis

    Article • Acta Crystallographica Section D Structural Biology, June 2024, International Union of Crystallography

    Dr Vengadesan krishnan

  2. Multi-omics approach for identifying CNV-associated lncRNA signatures with prognostic value in prostate cancer

    Article • Non-coding RNA Research, March 2024, Elsevier

    Dr. Dinesh Gupta, Dr Vengadesan krishnan

  3. Editorial: Functional insights into the probiotic mechanisms of surface protein action

    Article • Frontiers in Microbiology, January 2024, Frontiers

    Dr Vengadesan krishnan

  4. Determination of the Crystal Structure of the Cell Wall-Anchored Proteins and Pilins

    Article • October 2023, Springer Science + Business Media

    Dr Vengadesan krishnan

  5. Crystal structure of the pilus-specific sortase from early colonizing oral Streptococcus sanguinis captures an active open-lid conformation

    Article • International Journal of Biological Macromolecules, July 2023, Elsevier

    Dr Vengadesan krishnan

  6. Deciphering the substrate specificity of housekeeping sortase A and pilus-specific sortase C of probiotic bacterium Lactococcus lactis

    Article • Biochimie, September 2022, Elsevier

    Dr Vengadesan krishnan

  7. New structural insights into the PI‐2 pilus from Streptococcus oralis, an early dental plaque colonizer

    Article • FEBS Journal, May 2022, Wiley

    Dr Vengadesan krishnan

  8. Exploiting pilus-mediated bacteria-host interactions for health benefits

    Article • Molecular Aspects of Medicine, October 2021, Elsevier

    Dr Vengadesan krishnan

  9. LrpCBA pilus proteins of gut-dwelling Ligilactobacillus ruminis: crystallization and X-ray diffraction analysis

    Article • Acta Crystallographica Section F Structural Biology Communications, July 2021, International Union of Crystallography

    Dr Vengadesan krishnan

  10. Black pepper prevents anemia of inflammation by inhibiting hepcidin over-expression through BMP6-SMAD1/ IL6-STAT3 signaling pathway

    Article • Free Radical Biology and Medicine, May 2021, Elsevier

    Dr Vengadesan krishnan

  11. Black pepper and piperine induce anticancer effects on leukemia cell line

    Article • Toxicology Research, February 2021, Oxford University Press (OUP)

    Dr Vengadesan krishnan

  12. Wheatgrass inhibits the lipopolysaccharide-stimulated inflammatory effect in RAW 264.7 macrophages

    Article • Current Research in Toxicology, January 2021, Elsevier

    Dr Vengadesan krishnan

  13. Crystal structure of lactobacillar SpaC reveals an atypical five-domain pilus tip adhesin: Exposing its substrate-binding and assembly in SpaCBA pili

    Article • Journal of Structural Biology, September 2020, Elsevier

    Dr Vengadesan krishnan

  14. The adhesive PitA pilus protein from the early dental plaque colonizerStreptococcus oralis: expression, purification, crystallization and X-ray diffraction analysis

    Article • Acta Crystallographica Section F Structural Biology Communications, January 2020, International Union of Crystallography

    Dr Vengadesan krishnan

  15. SpaB, an atypically adhesive basal pilin from the lactobacillar SpaCBA pilus: crystallization and X-ray diffraction analysis

    Article • Acta Crystallographica Section F Structural Biology Communications, November 2019, International Union of Crystallography

    Dr Vengadesan krishnan

  16. Crystal structure of basal pilin SpaE reveals the molecular basis of its incorporation in the lactobacillar SpaFED pilus

    Article • Journal of Structural Biology, July 2019, Elsevier

    Dr Vengadesan krishnan

  17. A SUMOylation-dependent switch of RAB7 governs intracellular life and pathogenesis of Salmonella Typhimurium

    Article • Journal of Cell Science, December 2018, The Company of Biologists

    Dr Vengadesan krishnan

  18. Bent conformation of a backbone pilin N-terminal domain supports a three-stage pilus assembly mechanism

    Article • Communications Biology, July 2018, Springer Science + Business Media

    Dr Vengadesan krishnan

  19. Crystallization and X-ray diffraction analysis of SpaE, a basal pilus protein from the gut-adaptedLactobacillus rhamnosusGG

    Article • Acta Crystallographica Section F Structural Biology Communications, May 2017, International Union of Crystallography

    Dr Vengadesan krishnan

  20. Pili in Probiotic Bacteria

    Article • July 2016, IntechOpen

    Dr Vengadesan krishnan

  21. New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit

    Article • Scientific Reports, June 2016, Nature

    Dr Vengadesan krishnan

  22. Crystallization and X-ray Crystallographic Analysis of the Adhesive SpaC Pilin Subunit in the SpaCBA Pilus of Gut-adapted Lactobacillus rhamnosus GG

    Article • Protein and Peptide Letters, March 2016, Bentham Science Publishers

    Dr Vengadesan krishnan

  23. Pilins in gram-positive bacteria: A structural perspective

    Article • IUBMB Life, July 2015, Wiley

    Dr Vengadesan krishnan

  24. Purification, crystallization and preliminary X-ray diffraction analysis of SpaD, a backbone-pilin subunit encoded by the fimbrialspaFEDoperon inLactobacillus rhamnosusGG

    Article • Acta Crystallographica Section F Structural Biology Communications, January 2015, International Union of Crystallography

    Dr Vengadesan krishnan

  25. Purification, crystallization and preliminary crystallographic analysis of the SpaA backbone-pilin subunit from probioticLactobacillus rhamnosusGG

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2013, International Union of Crystallography

    Dr Vengadesan krishnan

  26. Secreted Proteases Control Autolysin-mediated Biofilm Growth ofStaphylococcus aureus

    Article • Journal of Biological Chemistry, August 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Vengadesan krishnan

  27. Purification, crystallization and preliminary X-ray diffraction analysis of theStaphylococcus epidermidisextracellular serine protease Esp

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, December 2012, International Union of Crystallography

    Dr Vengadesan krishnan

  28. Structural Differences between the Streptococcus agalactiae Housekeeping and Pilus-Specific Sortases: SrtA and SrtC1

    Article • PLoS ONE, August 2011, PLOS

    Dr Vengadesan krishnan

  29. Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development

    Article • Molecular Microbiology, July 2011, Wiley

    Dr Vengadesan krishnan

  30. Structural biology of gram-positive bacterial adhesins

    Article • Protein Science, April 2011, Wiley

    Dr Vengadesan krishnan

  31. A Model for Group B Streptococcus Pilus Type 1: The Structure of a 35-kDa C-Terminal Fragment of the Major Pilin GBS80

    Article • Journal of Molecular Biology, April 2011, Elsevier

    Dr Vengadesan krishnan

  32. The Crystal structure of the major pilin GBS80 of Streptococcus agalactiae 35 kDa C-terminal fragment

    Article • March 2011, Protein Data Bank, Rutgers University

    Dr Vengadesan krishnan

  33. The Crystal Structure of the Major Pilin GBS80 of Streptococcus agalactiae 35kDa C-terminal fragment

    Article • March 2011, Protein Data Bank, Rutgers University

    Dr Vengadesan krishnan

  34. Crystallography of Gram-Positive Bacterial Adhesins

    Article • January 2011, Springer Science + Business Media

    Dr Vengadesan krishnan

  35. Purification, crystallization and halide phasing of aStreptococcus agalactiaebackbone pilin GBS80 fragment

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, November 2010, International Union of Crystallography

    Dr Vengadesan krishnan

  36. Preliminary crystallographic study of theStreptococcus agalactiaesortases, sortase A and sortase C1

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, August 2010, International Union of Crystallography

    Dr Vengadesan krishnan

  37. The Crystal Structure of Cobra Venom Factor, a Cofactor for C3- and C5-Convertase CVFBb

    Article • Structure, April 2009, Elsevier

    Dr Vengadesan krishnan

  38. The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation

    Article • Acta Crystallographica Section D Biological Crystallography, February 2009, International Union of Crystallography

    Dr Vengadesan krishnan

  39. The crystal structure of cobra venom factor, a complement-activating protein from Naje Naja Kouthia

    Article • Molecular Immunology, October 2008, Elsevier

    Dr Vengadesan krishnan

  40. An IgG-like Domain in the Minor Pilin GBS52 of Streptococcus agalactiae Mediates Lung Epithelial Cell Adhesion

    Article • Structure, August 2007, Elsevier

    Dr Vengadesan krishnan

  41. The Crystal Structure of C2a, the Catalytic Fragment of Classical Pathway C3 and C5 Convertase of Human Complement

    Article • Journal of Molecular Biology, March 2007, Elsevier

    Dr Vengadesan krishnan

  42. Crystal structure of C2a, the catalytic subunit of classical pathway C3-convertase

    Article • Molecular Immunology, January 2007, Elsevier

    Dr Vengadesan krishnan

  43. A New Conformational Search Technique and Its Applications

    Article • ChemInform, May 2006, Wiley

    Dr Vengadesan krishnan

  44. Conformational studies on enkephalins using the MOLS technique

    Article • Biopolymers, August 2004, Wiley

    Dr Vengadesan krishnan

  45. Energy Landscape of Met-Enkephalin and Leu-Enkephalin Drawn Using Mutually Orthogonal Latin Squares Sampling

    Article • The Journal of Physical Chemistry, July 2004, American Chemical Society (ACS)

    Dr Vengadesan krishnan

  46. An application of experimental design using mutually orthogonal Latin squares in conformational studies of peptides

    Article • Biochemical and Biophysical Research Communications, April 2004, Elsevier

    Dr Vengadesan krishnan

  47. Enhanced Sampling of the Molecular Potential Energy Surface Using Mutually Orthogonal Latin Squares: Application to Peptide Structures

    Article • Biophysical Journal, May 2003, Elsevier

    Dr Vengadesan krishnan

  48. Crystal Structure of N, N'-Bis(3-(o-dimethylaminoimino-ethyl) -2-hydroxy-5-methyl)-benzylpiperazine

    Article • Crystal Research and Technology, August 2000, Wiley

    Dr Vengadesan krishnan