All Stories

  1. Cytostatic and cytotoxic effects of a hot water and methanol extract of Acokanthera oppositifolia in HepG2 hepatocarcinoma cells
  2. Comparative Evaluation of the Cytotoxicity of Doxorubicin in BT-20 Triple-Negative Breast Carcinoma Monolayer and Spheroid Cultures
  3. Highlights of basic and clinical pharmacology from Africa
  4. Utility of Therapeutic Drug Monitoring in Identifying Clinically Significant Interactions Between St. John's Wort and Prescription Drugs
  5. The VEGF/VEGFR Axis Revisited: Implications for Cancer Therapy
  6. Mechanisms facilitating the uptake of carboxyl–polythene glycol-functionalized gold nanoparticles into multicellular spheroids
  7. Design of Oleanolic Acid-based Hybrid Compounds as Potential Pharmaceutical Scaffolds
  8. Isolation and antioxidant activity of 5-methyldihydroflavasperone from ethanol leaf extract of Guiera senegalensis JF Gmel
  9. Synthesis, Antibacterial, and Cytotoxicity Evaluation of Oleanolic Acid-4-aminoquinoline Based Hybrid Compounds
  10. A Brief Updated Review of Advances to Enhance Resveratrol’s Bioavailability
  11. Zinc oxide nanoparticles induce oxidative stress and histopathological toxicity in the thyroid gland and liver of rats
  12. Novel N-benzylpiperidine carboxamide derivatives as potential cholinesterase inhibitors for the treatment of Alzheimer's disease
  13. Physicochemical and in vitro cytotoxicity evaluation of polymeric drugs for combination cancer therapy
  14. Synthesis and biological evaluation of 2-chloro-3-[(thiazol-2-yl)amino]-1,4-naphthoquinones
  15. Drugged driving in South Africa: An urgent need for review and reform
  16. Drugged driving in South Africa: An urgent need for review and reform
  17. Natural Products and/or Isolated Compounds on Wound Healing
  18. Herbal remedies used in wound healing
  19. Bioavailability of resveratrol: Possibilities for enhancement
  20. Beneficial anti oxidant effects of folic acid in methomyl toxicity
  21. Bulb extracts of Boophone disticha induce hepatotoxicity by perturbing growth, without significantly impacting cellular viability
  22. Attenuation of oxidative stress and artificial wound closure in C2C12 myoblasts induced by sequential extracts of Boerhavia diffusa
  23. Extracts of Terminalia sericea Enhance Cell Migratory Activity of Endothelial Hybrid and Fibroblast Cells In Vitro
  24. Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil
  25. Fatalities involving illicit drug use in Pretoria, South Africa, for the period 2003 - 2012
  26. Application of a LC–MS/MS method developed for the determination of p‐phenylenediamine, N‐acetyl‐p‐phenylenediamine and N,N‐diacetyl‐p‐phenylenediamine in human urine specimens
  27. Standardization of cassava Mahewu fermentation and assessment of the effects of iron sources used for fortification
  28. Development and validation of an LC–MS/MS method for determination of p-phenylenediamine and its metabolites in blood samples
  29. Medicinal plants and their derivatives with amyloid beta inhibitory activity as potential targets for drug discovery
  30. Herbal use for certain medical conditions in South Africa
  31. The effects of the natural enzyme, Pectinex Ultra SP-L, on human cell cultures and bacterial biofilms in vitro
  32. In vitro neuroprotective potential of four medicinal plants against rotenone-induced toxicity in SH-SY5Y neuroblastoma cells
  33. In vitro determination of the anti-aging potential of four southern African medicinal plants
  34. Attenuation of oxidative stress in U937 cells by polyphenolic-rich bark fractions of Burkea africana and Syzygium cordatum
  35. In vitro effect of N-acetylcysteine on hepatocyte injury caused by dichlorodiphenyltrichloroethane and its metabolites
  36. Comparative Toxicity of Pentachlorophenol with its Metabolites tetrachloro-1,2-hydroquinone and Tetrachloro-1,4-benzoquinone in HepG2 Cells
  37. Cytotoxicity and acetylcholinesterase inhibitory activity of an isolated crinine alkaloid from Boophane disticha (Amaryllidaceae)
  38. Effect of an alkaloidal fraction of Tabernaemontana elegans (Stapf.) on selected micro-organisms
  39. Herbal remedies affecting coagulation: A review
  40. In vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from southern Africa
  41. Antioxidant and acetylcholinesterase inhibitory activity of selected southern African medicinal plants
  42. Drug interactions in African herbal remedies
  43. Effects of selected South African plant extracts on haemolysis and coagulation
  44. Use of Yokukansan (TJ‐54) in the treatment of neurological disorders: a review
  45. Toxicity Testing of Two Medicinal Plants, Bridelia micrantha and Antidesma venosum
  46. In-vitro bioactivity of Venda medicinal plants used in the treatment of respiratory conditions
  47. The ability of Warburgia salutaris extracts to protect against crystalline silica-induced cell injury
  48. Antibacterial activity of Venda medicinal plants
  49. Senecio latifolius induces in vitro hepatocytotoxicity in a human cell lineThis article is one of a selection of papers published in this special issue (part 2 of 2) on the Safety and Efficacy of Natural Health Products.
  50. Screening of Venda medicinal plants for antifungal activity against Candida albicans
  51. Evaluation of Athrixia bush tea for cytotoxicity, antioxidant activity, caffeine content and presence of pyrrolizidine alkaloids
  52. Medicinal Applications and Toxicological Activities ofAloe. Products
  53. Cytotoxicity of six South African medicinal plant extracts used in the treatment of cancer
  54. Studies on antibacterial, anti-inflammatory and antioxidant activity of herbal remedies used in the treatment of benign prostatic hyperplasia and prostatitis
  55. URANIUM CONCENTRATIONS IN SOUTH AFRICAN HERBAL REMEDIES
  56. Nephrotoxicity Associated With Exposure to Plant Toxins, With Particular Reference to Africa
  57. Antioxidant and genotoxic properties of South African herbal extracts
  58. GC/MS identification of toxic pyrrolizidine alkaloids in traditional remedies given to two sets of twins
  59. Adulteration of South African Traditional Herbal Remedies
  60. Acute Renal Failure Associated with the Use of Traditional Folk Remedies in South Africa
  61. Studies on antibacterial, antioxidant and fibroblast growth stimulation of wound healing remedies from South Africa
  62. Antioxidant scavenging potential of South African export herbal teas
  63. CNS effects after muti ingestion: what is the cause?
  64. Phytomedicines for the prostate
  65. Traditional herbal remedies used by South African women for gynaecological complaints
  66. Death Due to Use of Traditional Medicines in Africa: A Preventable Cause of Neonatal and Infant Mortality
  67. The cytotoxic effects of a traditional Zulu remedy, impila (Callilepis laureola)
  68. Structural characterization of chromone C‐glucosides in a toxic herbal remedy
  69. Hepatic veno-occlusive disease as a result of a traditional remedy: confirmation of toxic pyrrolizidine alkaloids as the cause, using an in vitro technique
  70. A severe case of multiple metal poisoning in a child treated with a traditional medicine
  71. A fatal case of pepper poisoning
  72. Gas chromatographic–mass spectrometric confirmation of atractyloside in a patient poisoned with Callilepis laureola
  73. Pyrrolizidine Poisoning: A Neglected Area in Human Toxicology
  74. The effect of Senecio latifolius a plant used as a South African traditional medicine, on a human hepatoma cell line
  75. Letters to the Editor
  76. The toxicity of Callilepis laureola, a South African traditional herbal medicine
  77. The Biochemistry and Toxicity of Atractyloside: A Review
  78. Metal concentrations in plants and urine from patients treated with traditional remedies
  79. Clinical and Analytical Aspects of Pyrrolizidine Poisoning Caused by South African Traditional Medicines
  80. Detection of poisoning by Impila (Callilepis laureola) in a mother and child
  81. The Toxicology of African Herbal Remedies
  82. Purification and characterization of progesterone-binding globulin in the pregnant Cape porcupine, Hystrix africaeaustralis
  83. Concentrations of plasma total and unbound progesterone and testosterone during pregnancy in Cape porcupines, Hystrix africaeaustralis
  84. Sex-specific androgen binding in spotted hyaena (Crocuta crocuta) plasma
  85. Properties of proteins binding plasma progesterone in pregnant Cape porcupines (Hystrix africaeaustralis)
  86. Reproductive inhibition in the Cape porcupine, Hystrix africaeaustralis