All Stories

  1. Pifithrin-µ Induces Stress Granule Formation, Regulates Cell Survival, and Rewires Cellular Signaling
  2. Oxidative stress and signaling through EGFR and PKA pathways converge on the nuclear transport factor RanBP1
  3. Silica-coated LiYF4:Yb3+, Tm3+ upconverting nanoparticles are non-toxic and activate minor stress responses in mammalian cells
  4. Yeast profilin mutants inhibit classical nuclear import and alter the balance between actin and tubulin levels
  5. Curcumin and butyrate induce fibroblast senescence without the emergence of fibrosis biomarkers
  6. Valosin containing protein (VCP): initiator, modifier, and potential drug target for neurodegenerative diseases
  7. Combining Pr3+-Doped Nanoradiosensitizers and Endogenous Protoporphyrin IX for X-ray-Mediated Photodynamic Therapy of Glioblastoma Cells
  8. Multiple pathways promote microtubule stabilization in senescent intestinal epithelial cells
  9. CD26 is a senescence marker associated with reduced immunopotency of human adipose tissue-derived multipotent mesenchymal stromal cells
  10. Targeting nanoparticles to malignant tumors
  11. Curcumin nanoformulations to combat aging-related diseases
  12. Evaluation of Lanthanide-Doped Upconverting Nanoparticles for in Vitro and in Vivo Applications
  13. The Co-Chaperone HspBP1 Is a Novel Component of Stress Granules that Regulates Their Formation
  14. Nucleolar Organization and Functions in Health and Disease
  15. The Cytoskeleton as Regulator of Cell Signaling Pathways
  16. Exploring near-infrared absorbing nanocarriers to overcome cancer drug resistance
  17. Cellular senescence is associated with reorganization of the microtubule cytoskeleton
  18. MSC - targets for atherosclerosis therapy
  19. Inhibition of glioblastoma cell proliferation, invasion, and mechanism of action of a novel hydroxamic acid hybrid molecule
  20. Cytoplasmic RNA Granules in Somatic Maintenance
  21. Gold nanourchins and celastrol reorganize the nucleo- and cytoskeleton of glioblastoma cells
  22. The effects of lanthanide-doped upconverting nanoparticles on cancer cell biomarkers
  23. Cytoplasmic stress granules: Dynamic modulators of cell signaling and disease
  24. Dissecting the molecular mechanisms that impair stress granule formation in aging cells
  25. AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization
  26. Super-resolution microscopy reveals a golden kiss of death to mitochondria
  27. Immunofluorescence staining of kidney sections to monitor ischemia-induced damage
  28. Gold Nanoparticles Impinge on Nucleoli and the Stress Response in MCF7 Breast Cancer Cells
  29. Quantitative analysis of the interplay between hsc70 and its co-chaperone HspBP1
  30. Data in support of 5′AMP-activated protein kinase alpha regulates stress granule biogenesis
  31. Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1
  32. Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
  33. Impact of Leishmania Infection on Host Macrophage Nuclear Physiology and Nucleopore Complex Integrity
  34. Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis
  35. Detecting changes in the mitochondrial membrane potential by quantitative fluorescence microscopy
  36. Off to the Organelles - Killing Cancer Cells with Targeted Gold Nanoparticles
  37. Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization
  38. Nucleoli and Stress Granules: Connecting Distant Relatives
  39. Gold nanoparticles induce nuclear damage in breast cancer cells, which is further amplified by hyperthermia
  40. Pharmacological AMP Kinase Activators Target the Nucleolar Organization and Control Cell Proliferation
  41. Identification of Novel Markers That Demarcate the Nucleolus during Severe Stress and Chemotherapeutic Treatment
  42. Contributions of AMP kinase to the Pathogenesis of Type 2 Diabetes and Neurodegenerative Diseases
  43. Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport
  44. Automated Detection and Quantification of Granular Cell Compartments
  45. Implications of multipotent mesenchymal stromal cell aging
  46. Chaperones and Multitasking Proteins in the Nucleolus
  47. Spatial Proteomics Sheds Light on the Biology of Nucleolar Chaperones
  48. Nuclear Transport: A Switch for the Oxidative Stress—Signaling Circuit?
  49. AMP kinase: the missing link between type 2 diabetes and neurodegenerative diseases?
  50. Targeting AMPK for Therapeutic Intervention in Type 2 Diabetes
  51. Exploring the Nucleolar Proteome: Novel Concepts for Chaperone Trafficking and Function
  52. Computer-based fluorescence quantification: a novel approach to study nucleolar biology
  53. Nuclear envelopes show cell-type specific sensitivity for the permeabilization with digitonin.
  54. Chaperones and multitasking proteins in the nucleolus: networking together for survival?
  55. Traffic control at the nuclear pore
  56. Traffic control at the nuclear pore
  57. Dissecting the Signaling Events That Impact Classical Nuclear Import and Target Nuclear Transport Factors
  58. Interplay between MEK and PI3 kinase signaling regulates the subcellular localization of protein kinases ERK1/2 and Akt upon oxidative stress
  59. Optimized immunofluorescence staining protocol to detect the nucleoporin Nup98 in different subcellular compartments
  60. Oxidative stress mislocalizes and retains transport factor importin-α and nucleoporins Nup153 and Nup88 in nuclei where they generate high molecular mass complexes
  61. The localization of nuclear exporters of the importin-β family is regulated by Snf1 kinase, nutrient supply and stress
  62. The carrier Msn5p/Kap142p promotes nuclear export of the hsp70 Ssa4p and relocates in response to stress
  63. The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase
  64. Rapid purification of the outer mitochondrial membrane protein Por1p from Saccharomyces cerevisiae
  65. Starvation Promotes Nuclear Accumulation of the hsp70 Ssa4p in Yeast Cells
  66. Nonlamin components of the lamina: a paucity of proteins
  67. Targeting of the mammalian nucleoporin p62 to the nuclear envelope in the yeast Saccharomyces cerevisiae and HeLa cells
  68. Overexpression of the nucleoporin p62 induces nuclear fragmentation in HeLa cells
  69. Nucleocytoplasmic trafficking of proteins: With or without Ran?
  70. Targeting of the mammalian nucleoporin p62 to the nuclear envelope in the yeast Saccharomyces cerevisiae and HeLa cells
  71. Velcro in the nuclear envelope: LBR and LAPs
  72. Diffusion of Proteins Across the Nuclear Envelope of HeLa Cells
  73. The small GTPase Gsp1p binds to the repeat domain of the nucleoporin Nsp1p
  74. In VivoAnalysis of Nuclear Protein Traffic in Mammalian Cells
  75. Monitoring Nuclear Transport in HeLa Cells Using the Green Fluorescent Protein
  76. The yeast nucleoporin Nsp1 binds nuclear localization sequences in vitro
  77. Construction and in vivo analysis of new split lactose permeases
  78. Limited proteolysis of chicken gizzard 5′-nucleotidase
  79. Affinity labelling of 5′-nucleotidases with 5′-p-fluorosulphonylbenzoyladenosine
  80. Evidence for the direct interaction of chicken gizzard 5′-nucleotidase with laminin and fibronectin
  81. Studies on Transposable Element Ac of Zea Mays
  82. The N-terminal region of Escherichia coli lactose permease mediates membrane contact of the nascent polypeptide chain
  83. Limited proteolysis of lactose permease from Escherichia coli