All Stories

  1. Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives

    Article • European Journal of Medicinal Chemistry, June 2015, Elsevier

    Dr Tim J Snape

  2. A Baker–Venkataraman retro-Claisen cascade delivers a novel alkyl migration process for the synthesis of amides

    Article • Tetrahedron Letters, April 2015, Elsevier

    Dr Tim J Snape

  3. Approaches Toward Improving the Prognosis of Pediatric Patients With Glioma: Pursuing Mutant Drug Targets With Emerging Small Molecules

    Article • Seminars in Pediatric Neurology, March 2015, Elsevier

    Dr Tim J Snape

  4. Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr Tim J Snape

  5. Mechanism and Application of Baker–Venkataraman O→C Acyl Migration Reactions

    Article • Synthesis, December 2014, Thieme Publishing Group

    Dr Tim J Snape

  6. Aromatic amides and ureas as novel molecular probes for diagnosing disease

    Article • Medical Hypotheses, December 2014, Elsevier

    Dr Tim J Snape

  7. Cn -AMP2 from green coconut water is an anionic anticancer peptide

    Article • Journal of Peptide Science, September 2014, Wiley

    Dr Tim J Snape

  8. Small-molecule clinical trial candidates for the treatment of glioma

    Article • Drug Discovery Today, September 2014, Elsevier

    Dr Tim J Snape

  9. Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity

    Article • Bioorganic & Medicinal Chemistry Letters, August 2014, Elsevier

    Dr Tim J Snape

  10. Developing the Scope of O→C Aryl Migrations: Exploring Amide Substrates as Potential Precursors for Asymmetric Reactions

    Article • European Journal of Organic Chemistry, January 2014, Wiley

    Dr Tim J Snape

  11. Towards a sustainable synthesis of aniline-derived amides using an indirect chemoenzymatic process: challenges and successes

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr Tim J Snape

  12. Anionic Antimicrobial and Anticancer Peptides from Plants

    Article • Critical Reviews in Plant Sciences, September 2013, Taylor & Francis

    Dr Tim J Snape

  13. Synthetic oligoureas of metaphenylenediamine mimic host defence peptides in their antimicrobial behaviour

    Article • Bioorganic & Medicinal Chemistry Letters, May 2013, Elsevier

    Dr Tim J Snape

  14. Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma

    Article • Bioorganic & Medicinal Chemistry, April 2013, Elsevier

    Dr Tim J Snape

  15. Chiral 1,1-diaryl compounds as important pharmacophores

    Article • MedChemComm, January 2013, Royal Society of Chemistry

    Dr Tim J Snape

  16. Exploitation of a Candida antarctica lipase B-catalysed in situ carboxylic acid activation method for the synthesis of acetanilides

    Article • Journal of Molecular Catalysis B Enzymatic, November 2012, Elsevier

    Dr Tim J Snape

  17. ChemInform Abstract: Synthesis of 1,3-Disubstituted Azetidines via a Tandem Ring-Opening Ring-Closing Procedure.

    Article • ChemInform, September 2012, Wiley

    Dr Tim J Snape

  18. Thermodynamic interactions of a cis and trans benzanilide with Escherichia coli bacterial membranes

    Article • European Biophysics Journal, July 2012, Springer Science + Business Media

    Dr Tim J Snape

  19. Synthesis of 1,3-Disubstituted Azetidines via a Tandem Ring-Opening Ring-Closing Procedure

    Article • Synlett, May 2012, Thieme Publishing Group

    Dr Tim J Snape

  20. Exploiting conformationally restricted N,N′-dimethyl-N,N′-diarylureas as biologically active CC double bond analogues: synthesis and biological evaluation of combretastatin A-4 analogues

    Article • RSC Advances, January 2012, Royal Society of Chemistry

    Dr Tim J Snape

  21. Interactions between suitably functionalised conformationally distinct benzanilides and phospholipid monolayers

    Article • Soft Matter, January 2012, Royal Society of Chemistry

    Dr Tim J Snape

  22. ChemInform Abstract: Towards a Chemo-Enzymatic Method for the Asymmetric Synthesis of β-Amino Tertiary Alcohols.

    Article • ChemInform, April 2010, Wiley

    Dr Tim J Snape

  23. ChemInform Abstract: α-Arylation of Aryl Ketones: Expanding the Scope of the Truce-Smiles Rearrangement.

    Article • ChemInform, March 2009, Wiley

    Dr Tim J Snape

  24. ChemInform Abstract: A Truce on the Smiles Rearrangement: Revisiting an Old Reaction - The Truce-Smiles Rearrangement

    Article • ChemInform, February 2009, Wiley

    Dr Tim J Snape

  25. Towards a chemo-enzymatic method for the asymmetric synthesis of β-amino tertiary alcohols

    Article • Organic & Biomolecular Chemistry, January 2009, Royal Society of Chemistry

    Dr Tim J Snape

  26. Helix Persistence and Breakdown in Oligoureas of Metaphenylenediamine: Apparent Diastereotopicity as a Spectroscopic Marker of Helix Length in Solution

    Article • Journal of the American Chemical Society, November 2008, American Chemical Society (ACS)

    Dr Tim J Snape, Dr Lyn H Jones

  27. α-Arylation of Aryl Ketones: Expanding the Scope of the Truce-Smiles Rearrangement

    Article • Synlett, October 2008, Thieme Publishing Group

    Dr Tim J Snape

  28. Enzymatic desymmetrisation of (2-hydroxymethyl-oxiranyl)-methanol in organic solvents

    Article • Tetrahedron Asymmetry, August 2008, Elsevier

    Dr Tim J Snape

  29. ChemInform Abstract: Recent Advances in the Semi-Pinacol Rearrangement of α-Hydroxy Epoxides and Related Compounds

    Article • ChemInform, February 2008, Wiley

    Dr Tim J Snape

  30. A truce on the Smiles rearrangement: revisiting an old reaction—the Truce–Smiles rearrangement

    Article • Chemical Society Reviews, January 2008, Royal Society of Chemistry

    Dr Tim J Snape

  31. Nitrile reduction using Pd/C

    Article • April 2007, Royal Society of Chemistry

    Dr Tim J Snape

  32. Application of the Semi-Pinacol Rearrangement Towards the Generation of Alkenyl-Substituted Quaternary Carbon Centers.

    Article • ChemInform, March 2007, Wiley

    Dr Tim J Snape

  33. Achieving conformational control over C–C, C–N and C–O bonds in biaryls, N,N′-diarylureas and diaryl ethers: advantages of a relay axis

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Dr Mark S. Betson, Dr Tim J Snape

  34. Recent advances in the semi-pinacol rearrangement of α-hydroxy epoxides and related compounds

    Article • Chemical Society Reviews, January 2007, Royal Society of Chemistry

    Dr Tim J Snape

  35. A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A

    Article • Chemical Communications, January 2007, Royal Society of Chemistry

    Dr Tim J Snape

  36. Application of the semi-pinacol rearrangement towards the generation of alkenyl-substituted quaternary carbon centres

    Article • Organic & Biomolecular Chemistry, January 2006, Royal Society of Chemistry

    Dr Tim J Snape

  37. Synthesis and Revision of the Stereochemistry of a Cyclopentenone Natural Product Isolated from Ascomycete Strain A23-98.

    Article • ChemInform, July 2004, Wiley

    Dr Tim J Snape

  38. Synthesis and revision of the stereochemistry of a cyclopentenone natural product isolated from ascomycete strain A23-98

    Article • Tetrahedron, March 2004, Elsevier

    Dr Tim J Snape

  39. Synthesis of 4-azacyclopent-2-enones and 5,5-dialkyl-4-azacyclopent-2-enones

    Article • Tetrahedron, March 2004, Elsevier

    Dr Tim J Snape

  40. Enzymatic Oxidation Chemistry

    Article • Wiley

    Dr Tim J Snape