All Stories

  1. HBV‐Induced Carcinogenesis: Mechanisms, Correlation With Viral Suppression, and Implications for Treatment

    Article • Liver International, December 2024, Wiley

    Thomas Tu

  2. Perspectives of People Living With Chronic Hepatitis D: Impact of Disease and Unmet Needs Along the Care Cascade

    Article • Journal of Viral Hepatitis, September 2024, Wiley

    Thomas Tu

  3. Hepatitis B Viral Protein HBx: Roles in Viral Replication and Hepatocarcinogenesis

    Article • Viruses, August 2024, MDPI AG

    Thomas Tu

  4. Major open questions in the hepatitis B and D field – Proceedings of the inaugural International emerging hepatitis B and hepatitis D researchers workshop

    Article • Virology, July 2024, Elsevier

    Thomas Tu

  5. Special Issue “Hepatitis B Virus: New Breakthroughs to Conquer an Ancient Disease”

    Article • Viruses, October 2023, MDPI AG

    Thomas Tu

  6. Targeting Hepatitis B Virus DNA Using Designer Gene Editors

    Article • Clinics in Liver Disease, July 2023, Elsevier

    Thomas Tu

  7. Novel Assays to Solve the Clinical and Scientific Challenges of Chronic Hepatitis B

    Article • Clinics in Liver Disease, July 2023, Elsevier

    Thomas Tu

  8. Pathway to global elimination of hepatitis B: HBV cure is just the first step

    Article • Hepatology, May 2023, Wolters Kluwer Health

    Thomas Tu

  9. Inhibition of cellular factor TM6SF2 suppresses secretion pathways of Hepatitis B, Hepatitis C and Hepatitis D viruses

    Article • April 2023, Research Square

    Thomas Tu

  10. Domestic Cat Hepadnavirus: Molecular Epidemiology and Phylogeny in Cats in Hong Kong

    Article • Viruses, January 2023, MDPI AG

    Thomas Tu

  11. Prevalence and Genomic Sequence Analysis of Domestic Cat Hepadnavirus in the United States

    Article • Viruses, September 2022, MDPI AG

    Thomas Tu

  12. Mitosis of hepatitis B virus-infected cells in vitro results in uninfected daughter cells

    Article • JHEP Reports, September 2022, Elsevier

    Thomas Tu

  13. Stigma: a major barrier to hepatitis B elimination

    Article • Nature Reviews Gastroenterology & Hepatology, August 2022, Springer Science + Business Media

    Thomas Tu

  14. Surrogate Markers for Hepatitis B Virus Covalently Closed Circular DNA

    Article • Seminars in Liver Disease, April 2022, Thieme Publishing Group

    Thomas Tu

  15. Approaches to quantifying hepatitis B virus covalently closed circular DNA

    Article • Clinical and Molecular Hepatology, April 2022, The Korean Association for the Study of the Liver (KAMJE)

    Thomas Tu

  16. Viral integrations in chronic hepatitis B infection: Purposeless passenger or problematic promoter of persistence?

    Article • Hepatology, March 2022, Wolters Kluwer Health

    Thomas Tu

  17. A River From the Liver: Detecting Hepatocyte Genomic DNA in Urine

    Article • Hepatology Communications, October 2021, Wolters Kluwer Health

    Thomas Tu

  18. The Inaugural Australian Centre for Hepatitis Virology Public Panel Discussion on Viral Hepatitis Research—Lessons in Scientific Community Outreach

    Article • Viruses, September 2021, MDPI AG

    Thomas Tu

  19. Viral Biomarkers for Hepatitis B Virus-Related Hepatocellular Carcinoma Occurrence and Recurrence

    Article • Frontiers in Microbiology, June 2021, Frontiers

    Thomas Tu

  20. De novo synthesis of hepatitis B virus nucleocapsids is dispensable for the maintenance and transcriptional regulation of cccDNA

    Article • JHEP Reports, February 2021, Elsevier

    Thomas Tu

  21. Hepatitis B Virus DNA Integration: In Vitro Models for Investigating Viral Pathogenesis and Persistence

    Article • Viruses, January 2021, MDPI AG

    Thomas Tu

  22. A sensitive and Specific PCR-based Assay to Quantify Hepatitis B Virus Covalently Closed Circular (ccc) DNA While Preserving Cellular DNA

    Article • BIO-PROTOCOL, January 2021, Bio-Protocol, LLC

    Thomas Tu

  23. Special Issue “Hepatitis B Virus Infection: From Diagnostics to Treatments”

    Article • Viruses, November 2020, MDPI AG

    Thomas Tu

  24. A novel method to precisely quantify hepatitis B virus covalently closed circular (ccc)DNA formation and maintenance

    Article • Antiviral Research, September 2020, Elsevier

    Thomas Tu

  25. The evolution and clinical impact of hepatitis B virus genome diversity

    Article • Nature Reviews Gastroenterology & Hepatology, May 2020, Springer Science + Business Media

    Thomas Tu

  26. The Lived Experience of Chronic Hepatitis B: A Broader View of Its Impacts and Why We Need a Cure

    Article • Viruses, May 2020, MDPI AG

    Thomas Tu

  27. Virus Genotype-Dependent Transcriptional Alterations in Lipid Metabolism and Inflammation Pathways in the Hepatitis C Virus-infected Liver

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Thomas Tu

  28. Generation and characterization of a stable cell line persistently replicating and secreting the human hepatitis delta virus

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Thomas Tu

  29. Analyse chromosomal integrierter HBV-DNA durch inverse nested PCR

    Article • BIOspektrum, May 2019, Springer Science + Business Media

    Thomas Tu

  30. Journal Watch: Dr Tu looks back at the most important research articles released in 2018 relating to models and biomarkers of hepatocellular carcinoma

    Article • Hepatic Oncology, March 2019, Future Medicine

    Thomas Tu

  31. Hepatitis B virus (HBV) DNA integration is not driven by viral proteins

    Article • Zeitschrift für Gastroenterologie, January 2019, Thieme Publishing Group

    Thomas Tu

  32. Detection of Low Copy Number Integrated Viral DNA Formed by <em>In Vitro</em> Hepatitis B Infection

    Article • Journal of Visualized Experiments, November 2018, MyJove Corporation

    Thomas Tu

  33. Detection of Low Copy Number Integrated Viral DNA Formed by <em>In Vitro</em> Hepatitis B Infection

    Article • Journal of Visualized Experiments, November 2018, MyJove Corporation

    Thomas Tu

  34. Sequence analysis of integrated hepatitis B virus DNA during HBeAg-seroconversion

    Article • Emerging Microbes & Infections, August 2018, Taylor & Francis

    Thomas Tu

  35. Cellular Genomic Sites of Hepatitis B Virus DNA Integration

    Article • Genes, July 2018, MDPI AG

    Thomas Tu

  36. Virus entry and its inhibition to prevent and treat hepatitis B and hepatitis D virus infections

    Article • Current Opinion in Virology, June 2018, Elsevier

    Thomas Tu

  37. HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon

    Article • Gastroenterology, May 2018, Elsevier

    Ralf Bartenschlager, Thomas Tu

  38. Hepatitis B virus integration into cellular genome

    Article • Journal of Virology, February 2018, ASM Journals

    Thomas Tu

  39. HBV bypasses the innate immune system and does not protect HCV against the antiviral effect of IFN

    Article • Zeitschrift für Gastroenterologie, January 2018, Thieme Publishing Group

    Thomas Tu

  40. HBV DNA Integration: Molecular Mechanisms and Clinical Implications

    Article • Viruses, April 2017, MDPI AG

    Thomas Tu

  41. Chronic viral hepatitis and its association with liver cancer

    Article • Biological Chemistry, January 2017, De Gruyter

    Thomas Tu, Ralf Bartenschlager

  42. Integrated analysis of exosomal microRNA, gene, and pathway regulatory networks in fibrosis and hepatocarcinogenesis

    Article • Journal of Hepatology, January 2017, Elsevier

    Thomas Tu

  43. Viral Hepatitis

    Article • January 2017, Elsevier

    Thomas Tu

  44. Whole genome sequencing analysis of familial primary sclerosing cholangitis

    Article • Journal of Hepatology, January 2017, Elsevier

    Thomas Tu

  45. Detection of Hepatocyte Clones Containing Integrated Hepatitis B Virus DNA Using Inverse Nested PCR

    Article • December 2016, Springer Science + Business Media

    Thomas Tu

  46. Basic Science Liver

    Article • Journal of Gastroenterology and Hepatology, October 2016, Wiley

    Thomas Tu

  47. Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma

    Article • PLOS One, September 2016, PLOS

    Thomas Tu

  48. Abstracts of the 25th Annual Conference of APASL, February 20–24, 2016, Tokyo, Japan

    Article • Hepatology International, February 2016, Springer Science + Business Media

    Thomas Tu

  49. Differential Microrna Expression in Plasma Microvesicles Predict Hepatocellular Carcinoma Regulatory Pathways

    Article • Journal of Hepatology, January 2016, Elsevier

    Thomas Tu

  50. Multi-Omics Landscape of Precancerous Liver Disease

    Article • Journal of Hepatology, January 2016, Elsevier

    Thomas Tu

  51. Hepatocytes in liver injury: Victim, bystander, or accomplice in progressive fibrosis?

    Article • Journal of Gastroenterology and Hepatology, November 2015, Wiley

    Thomas Tu

  52. Analysis of Post-Liver Transplant Hepatitis C Virus Recurrence Using Serial Cluster of Differentiation Antibody Microarrays

    Article • Transplantation, September 2015, Wolters Kluwer Health

    Thomas Tu

  53. Basic Science - Liver

    Article • Journal of Gastroenterology and Hepatology, September 2015, Wiley

    Thomas Tu

  54. P0268 : Accumulation of deleterious passenger mutations during liver injury progression to hepatocellular carcinoma

    Article • Journal of Hepatology, April 2015, Elsevier

    Thomas Tu

  55. Conceptual models for the initiation of hepatitis B virus-associated hepatocellular carcinoma

    Article • Liver International, February 2015, Wiley

    Thomas Tu

  56. Clonal expansion of hepatocytes with a selective advantage occurs during all stages of chronic hepatitis B virus infection

    Article • Journal of Viral Hepatitis, January 2015, Wiley

    Thomas Tu

  57. Our experts highlight the most important research articles across the spectrum of topics relevant to the field of hepatic oncology

    Article • Hepatic Oncology, January 2015, Future Medicine

    Thomas Tu

  58. Poster Presentation Abstracts

    Article • Asia-Pacific Journal of Clinical Oncology, November 2014, Wiley

    Thomas Tu

  59. Hepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver Fibrogenesis

    Article • PLOS One, July 2014, PLOS

    Thomas Tu

  60. Novel Aspects of the Liver Microenvironment in Hepatocellular Carcinoma Pathogenesis and Development

    Article • International Journal of Molecular Sciences, May 2014, MDPI AG

    Thomas Tu

  61. Advances in and the future of treatments for hepatitis C

    Article • Expert Review of Gastroenterology & Hepatology, May 2014, Taylor & Francis

    Thomas Tu

  62. Endoscopy Upper

    Article • Journal of Gastroenterology and Hepatology, September 2013, Wiley

    Thomas Tu

  63. “Testing your methyl”: DNA methylation profiling of serum DNA of HCC patients

    Article • Hepatology International, July 2013, Springer Science + Business Media

    Thomas Tu