Thomas Michiels – Kudos: Growing the influence of research

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Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic

Article • PLoS Pathogens, December 2022, PLOS

Thomas Michiels
A case of convergent evolution: Several viral and bacterial pathogens hijack RSK kinases through a common linear motif

Article • Proceedings of the National Academy of Sciences, January 2022, Proceedings of the National Academy of Sciences

Thomas Michiels, Pharmacy Resident Nicolas CAPELLI
Nucleocytoplasmic Trafficking Perturbation Induced by Picornaviruses

Article • Viruses, June 2021, MDPI AG

Thomas Michiels
The Leader Protein of Theiler's Virus Prevents the Activation of PKR

Article • Journal of Virology, October 2019, ASM Journals

Thomas Michiels
IFN-λ Decreases Murid Herpesvirus-4 Infection of the Olfactory Epithelium but Fails to Prevent Virus Reactivation in the Vaginal Mucosa

Article • Viruses, August 2019, MDPI AG

Thomas Michiels
A novel mechanism of RNase L inhibition: Theiler's virus L* protein prevents 2-5A from binding to RNase L

Article • PLoS Pathogens, April 2018, PLOS

Thomas Michiels
Interferon lambda (IFN-λ) efficiently blocks norovirus transmission in a mouse model

Article • Antiviral Research, January 2018, Elsevier

Johan Neyts, Thomas Michiels
Nonstructural Protein L* Species Specificity Supports a Mouse Origin for Vilyuisk Human Encephalitis Virus

Article • Journal of Virology, April 2017, ASM Journals

Professor Fred R. Opperdoes, Thomas Michiels
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes

Article • Journal of Neurochemistry, March 2017, Wiley

Thomas Michiels
Conserved Fever Pathways across Vertebrates: A Herpesvirus Expressed Decoy TNF-α Receptor Delays Behavioral Fever in Fish

Article • Cell Host & Microbe, February 2017, Elsevier

Thomas Michiels
Neurotropism of Saffold virus in a mouse model

Article • Journal of General Virology, June 2016, Society for General Microbiology

Thomas Michiels
Study of hepatitis E virus infection of genotype 1 and 3 in mice with humanised liver

Article • Gut, March 2016, BMJ

Lander Foquet, Johan Neyts, Thomas Michiels
Cellular microRNAs Repress Vesicular Stomatitis Virus but Not Theiler’s Virus Replication

Article • Viruses, March 2016, MDPI AG

Thomas Michiels
Abortively Infected Astrocytes Appear To Represent the Main Source of Interferon Beta in the Virus-Infected Brain

Article • Journal of Virology, February 2016, ASM Journals

Thomas Michiels
Inhibition of the OAS/RNase L pathway by viruses

Article • Current Opinion in Virology, December 2015, Elsevier

Thomas Michiels
The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler’s Virus Replication

Article • PLoS ONE, July 2015, PLOS

Thomas Michiels
Characterization of Ribosomal Frameshifting in Theiler's Murine Encephalomyelitis Virus

Article • Journal of Virology, June 2015, ASM Journals

Thomas Michiels
Lack of effect of Theiler’s murine encephalomyelitis virus infection on system xc−

Article • Neuroscience Letters, April 2015, Elsevier

Thomas Michiels
Human but Not Mouse Hepatocytes Respond to Interferon-Lambda In Vivo

Article • PLoS ONE, January 2014, PLOS

Thomas Michiels
Inefficient Type I Interferon-Mediated Antiviral Protection of Primary Mouse Neurons Is Associated with the Lack of Apolipoprotein L9 Expression

Article • Journal of Virology, January 2014, ASM Journals

Thomas Michiels
Interferon-λ in the Context of Viral Infections: Production, Response and Therapeutic Implications

Article • Journal of Innate Immunity, January 2014, Karger Publishers

Thomas Michiels
IFN-ε Is Constitutively Expressed by Cells of the Reproductive Tract and Is Inefficiently Secreted by Fibroblasts and Cell Lines

Article • PLoS ONE, August 2013, PLOS

Professor Frederic Clotman, Thomas Michiels
Evasion of Antiviral Innate Immunity by Theiler's Virus L* Protein through Direct Inhibition of RNase L

Article • PLoS Pathogens, June 2013, PLOS

Thomas Michiels
Antiviral Type I and Type III Interferon Responses in the Central Nervous System

Article • Viruses, March 2013, MDPI AG

Thomas Michiels
The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly

Article • Journal of Virology, July 2011, ASM Journals

Thomas Michiels
IFN-λ determines the intestinal epithelial antiviral host defense

Article • Proceedings of the National Academy of Sciences, April 2011, Proceedings of the National Academy of Sciences

Thomas Michiels
Theiler's Virus L* Protein Is Targeted to the Mitochondrial Outer Membrane

Article • Journal of Virology, January 2011, ASM Journals

Thomas Michiels
What Have We Learned from the IL28 Receptor Knockout Mouse?

Article • Journal of Interferon & Cytokine Research, August 2010, Mary Ann Liebert Inc

Thomas Michiels
Type I Interferon Signaling Contributes to Chronic Inflammation in a Murine Model of Silicosis

Article • Toxicological Sciences, May 2010, Oxford University Press (OUP)

Thomas Michiels
Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

Article • Journal of Virology, March 2010, ASM Journals

Thomas Michiels
Differential IFN-α/β production suppressing capacities of the leader proteins of mengovirus and foot-and-mouth disease virus

Article • Cellular Microbiology, March 2010, Hindawi Publishing Corporation

Thomas Michiels
Random Mutagenesis Defines a Domain of Theiler's Virus Leader Protein That Is Essential for Antagonism of Nucleocytoplasmic Trafficking and Cytokine Gene Expression

Article • Journal of Virology, August 2009, ASM Journals

Thomas Michiels
Inhibition of mRNA export and dimerization of interferon regulatory factor 3 by Theiler's virus leader protein

Article • Journal of General Virology, January 2009, Society for General Microbiology

Thomas Michiels
PCR-Based Simultaneous Analysis of the Interferon-Alpha Family Reveals Distinct Kinetics for Early Interferons

Article • Journal of Interferon & Cytokine Research, November 2008, Mary Ann Liebert Inc

Thomas Michiels
TLR Ligand-Induced Type I IFNs Affect Thymopoiesis

Article • The Journal of Immunology, May 2008, The American Association of Immunologists

Thomas Michiels
IFN-Lambda (IFN-λ) Is Expressed in a Tissue-Dependent Fashion and Primarily Acts on Epithelial Cells In Vivo

Article • PLoS Pathogens, March 2008, PLOS

Thomas Michiels
Anti-IL-17A Autovaccination Prevents Clinical and Histological Manifestations of Experimental Autoimmune Encephalomyelitis

Article • Annals of the New York Academy of Sciences, September 2007, Wiley

Thomas Michiels
The mengovirus leader protein blocks interferon-α/β gene transcription and inhibits activation of interferon regulatory factor 3

Article • Cellular Microbiology, July 2007, Hindawi Publishing Corporation

Thomas Michiels
Type I interferon response in the central nervous system

Article • Biochimie, June 2007, Elsevier

Thomas Michiels
La Crosse Bunyavirus Nonstructural Protein NSs Serves To Suppress the Type I Interferon System of Mammalian Hosts

Article • Journal of Virology, March 2007, ASM Journals

Friedemann Weber, Thomas Michiels
N-Glycosylation of Murine IFN-βin a Putative Receptor-Binding Region

Article • Journal of Interferon & Cytokine Research, June 2006, Mary Ann Liebert Inc

Thomas Michiels
Neurons produce type I interferon during viral encephalitis

Article • Proceedings of the National Academy of Sciences, May 2006, Proceedings of the National Academy of Sciences

Friedemann Weber, Thomas Michiels
Cardiovirus leader proteins are functionally interchangeable and have evolved to adapt to virus replication fitness

Article • Journal of General Virology, May 2006, Society for General Microbiology

Thomas Michiels
THE GENETICS OF THE PERSISTENT INFECTION AND DEMYELINATING DISEASE CAUSED BY THEILER'S VIRUS

Article • Annual Review of Microbiology, October 2005, Annual Reviews

Thomas Michiels
Characterization of the Murine Alpha Interferon Gene Family

Article • Journal of Virology, August 2004, ASM Journals

Thomas Michiels
Role of the Interleukin (IL)-28 Receptor Tyrosine Residues for Antiviral and Antiproliferative Activity of IL-29/Interferon-λ1

Article • Journal of Biological Chemistry, July 2004, Elsevier

Thomas Michiels
The Leader Protein of Theiler's Virus Interferes with Nucleocytoplasmic Trafficking of Cellular Proteins

Article • Journal of Virology, April 2004, ASM Journals

Thomas Michiels
Characterization of Interferon-α 13, a Novel Constitutive Murine Interferon-α Subtype

Article • Journal of Biological Chemistry, November 2003, Elsevier

Thomas Michiels
Non-AUG-Initiated Internal Translation of the L* Protein of Theiler's Virus and Importance of This Protein for Viral Persistence

Article • Journal of Virology, November 2002, ASM Journals

Thomas Michiels
Mutations That Affect the Tropism of DA and GDVII Strains of Theiler's Virus In Vitro Influence Sialic Acid Binding and Pathogenicity

Article • Journal of Virology, August 2002, ASM Journals

Thomas Michiels
The Leader Protein of Theiler's Virus Inhibits Immediate-Early Alpha/Beta Interferon Production

Article • Journal of Virology, September 2001, ASM Journals

Thomas Michiels
Influence of the Theiler's Virus L∗ Protein on Macrophage Infection, Viral Persistence, and Neurovirulence

Article • Journal of Virology, October 2000, ASM Journals

Thomas Michiels
A coding RNA sequence acts as a replication signal in cardioviruses

Article • Proceedings of the National Academy of Sciences, September 1999, Proceedings of the National Academy of Sciences

Thomas Michiels
Adaptation of Theiler's Virus to L929 Cells: Mutations in the Putative Receptor Binding Site on the Capsid Map to Neutralization Sites and Modulate Viral Persistence

Article • Virology, May 1998, Elsevier

Thomas Michiels
Analysis of the Leader and Capsid Coding Regions of Persistent and Neurovirulent Strains of Theiler's Virus

Article • Virology, December 1995, Elsevier

Thomas Michiels
Individual chaperones required for Yop secretion by Yersinia.

Article • Proceedings of the National Academy of Sciences, October 1994, Proceedings of the National Academy of Sciences

Dr Pierre Wattiau, Thomas Michiels
ymoA, a Yersinia enterocolitica chromosomal gene modulating the expression of virulence functions

Article • Molecular Microbiology, May 1991, Wiley

Thomas Michiels
Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica.

Article • Journal of Bacteriology, January 1991, ASM Journals

Thomas Michiels
Secretion of hybrid proteins by the Yersinia Yop export system.

Article • Journal of Bacteriology, January 1991, ASM Journals

Thomas Michiels
The pYV plasmid ofYersiniaencodes a lipoprotein, YlpA, related to TraT

Article • Molecular Microbiology, September 1990, Wiley

Thomas Michiels
Secretion of Yop proteins by Yersiniae

Article • Infection and Immunity, September 1990, ASM Journals

Thomas Michiels
Site-specific recombinations between direct and inverted res sites of Tn2501

Article • Plasmid, November 1989, Elsevier

Thomas Michiels
The Yersinia yop regulon

Article • Molecular Microbiology, October 1989, Wiley

Thomas Michiels
Homology between virF, the transcriptional activator of the Yersinia virulence regulon, and AraC, the Escherichia coli arabinose operon regulator.

Article • Journal of Bacteriology, January 1989, ASM Journals

Thomas Michiels
Nucleotide sequence and transcription analysis of yop51 from Yersinia enterocolitica W22703

Article • Microbial Pathogenesis, December 1988, Elsevier

Thomas Michiels
A new method for the physical and genetic mapping of large plasmids: application to the localisation of the virulence determinants on the 90 kb plasmid of Salmonella typhimurium

Article • Microbial Pathogenesis, August 1987, Elsevier

Thomas Michiels
Tn2501, a component of the lactose transposon Tn951, is an example of a new category of class II transposable elements.

Article • Journal of Bacteriology, January 1987, ASM Journals

Thomas Michiels
Tn951 derivatives designed for high-frequency plasmid-specific transposition and deletion mutagenesis

Article • Gene, January 1986, Elsevier

Thomas Michiels