All Stories

  1. Biological therapies at 25 years: from incremental advances to revolutionary transformations
  2. Thyroid eye disease: revolutionizing treatment with IGF-1 receptor targeted therapy
  3. Beyond the injection: delivery systems reshaping retinal disease management
  4. Autoimmune neuro-ophthalmic disorders: pathophysiologic mechanisms and targeted biologic therapies
  5. Suprachoroidal drug delivery: a versatile therapeutic platform
  6. Three-Year Clinical Outcomes in Geographic Atrophy: An Analysis of 18,712 Patient Eyes
  7. Long-acting delivery and therapies for neovascular age-related macular degeneration
  8. Safety and Tolerability of Suprachoroidal Axitinib, CLS-AX, for Neovascular AMD; Phase 1/2a Open-Label, Dose-Escalation Trial
  9. Gene Therapy for Non-Hereditary Retinal Disease: Age-Related Macular Degeneration, Diabetic Retinopathy, and Beyond
  10. Safety and Efficacy of CLS-TA by Anatomic Location of Inflammation: Results from the Phase 3 PEACHTREE Clinical Trial
  11. Effect of Race and Insurance Status on Treatment and Outcomes in Diabetic Retinopathy: Analysis of 43 274 Eyes Using the IRIS Registry
  12. The complement system: a novel therapeutic target for Age-related macular degeneration
  13. The evolving therapeutic landscape of diabetic retinopathy
  14. Optical coherence tomography outcomes as biomarkers for disease status, visual function, and prognosis in diabetic macular edema
  15. Aging Effects on Optic Nerve Neurodegeneration
  16. Triamcinolone Acetonide Suprachoroidal Injectable Suspension for Uveitic Macular Edema: Integrated Analysis of Two Phase 3 Studies
  17. Advancements in ocular gene therapy delivery: vectors and subretinal, intravitreal, and suprachoroidal techniques
  18. Progress in the pharmacotherapy of uveitis: the art of personalized care
  19. Longer-Term Anti-VEGF Therapy Outcomes in Neovascular Age-Related Macular Degeneration, Diabetic Macular Edema, and Vein Occlusion-Related Macular Edema
  20. A randomized, double-masked, multicenter trial of topical acrizanib (LHA510), a tyrosine kinase VEGF-receptor inhibitor, in treatment-experienced subjects with neovascular age-related macular degeneration
  21. Sustained release glaucoma therapies: Novel modalities for overcoming key treatment barriers associated with topical medications
  22. Disease Progression Pathways of Wet AMD: Opportunities for New Target Discovery
  23. Suprachoroidal CLS‐TA versus Rescue Therapies for the Treatment of Uveitic Macular Edema: A Post Hoc Analysis of PEACHTREE
  24. OCT Anatomic and Temporal Biomarkers in Uveitic Macular Edema
  25. Suprachoroidal CLS-TA with and without Systemic Corticosteroid and/or Steroid-Sparing Therapy: A Post-Hoc Analysis of the Phase 3 PEACHTREE Clinical Trial
  26. Genetics of Diabetic Retinopathy, a Leading Cause of Irreversible Blindness in the Industrialized World
  27. Glaucoma Heritability: Molecular Mechanisms of Disease
  28. Physics-based modeling of Age-related Macular Degeneration—A theoretical approach to quantify retinal and choroidal contributions to macular oxygenation
  29. Understanding the genetic pathology of Stargardt disease: a review of current findings and challenges
  30. Suprachoroidal Delivery of Small Molecules, Nanoparticles, Gene and Cell Therapies for Ocular Diseases
  31. Suprachoroidal CLS-TA for non-infectious uveitis: an open-label, safety trial (AZALEA)
  32. Biomechanics of suprachoroidal drug delivery: From benchtop to clinical investigation in ocular therapies
  33. Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations
  34. RNA Therapeutics for Retinal Diseases
  35. Visual acuity outcomes and anti-VEGF therapy intensity in macular oedema due to retinal vein occlusion: a real-world analysis of 15 613 patient eyes
  36. Microbial Spectrum and Antibacterial Susceptibility of Endophthalmitis Cultures in a Tertiary Referral Center in the Midwestern United States: An Analysis From 295 Patients
  37. Anti-Integrin therapy for retinovascular diseases
  38. Evolution of Primary Scleral Buckling Surgery: A Modified Lean Six Sigma Technique to Improve Surgical Efficiency
  39. Visual acuity outcomes and anti-VEGF therapy intensity in diabetic macular oedema: a real-world analysis of 28 658 patient eyes
  40. Suprachoroidal Delivery of Viral and Nonviral Gene Therapy for Retinal Diseases
  41. Retinal oximetry in glaucoma: investigations and findings reviewed
  42. Voretigene neparvovec-rzyl for treatment of RPE65-mediated inherited retinal diseases: a model for ocular gene therapy development
  43. Investigational plasma kallikrein inhibitors for the treatment of diabetic macular edema: an expert assessment
  44. Visual Acuity Outcomes and Anti–Vascular Endothelial Growth Factor Therapy Intensity in Neovascular Age-Related Macular Degeneration Patients
  45. Efficacy and Safety of Suprachoroidal CLS-TA for Macular Edema Secondary to Noninfectious Uveitis
  46. Current and upcoming anti-VEGF therapies and dosing strategies for the treatment of neovascular AMD: a comparative review
  47. Cost-effectiveness of Voretigene Neparvovec-rzyl vs Standard Care for RPE65-Mediated Inherited Retinal Disease
  48. Tie-2/Angiopoietin pathway modulation as a therapeutic strategy for retinal disease
  49. Important Considerations in Modeling the Cost-Effectiveness for the First Food and Drug Administration–Approved Gene Therapy and Implications for Future One-Time Therapies
  50. Efficacy and safety of bromfenac 0.075% formulated in DuraSite for pain and inflammation in cataract surgery
  51. Innovative therapies for neovascular age-related macular degeneration
  52. Vascular dysfunction in retinitis pigmentosa
  53. Complement inhibition as a therapeutic strategy in retinal disorders
  54. Estimation of impact of RPE65-mediated inherited retinal disease on quality of life and the potential benefits of gene therapy
  55. Pathological Consequences of Vascular Alterations in the Eye
  56. Vitreous Pathology
  57. Vitreous Physiology
  58. Real-world Outcomes of Anti–Vascular Endothelial Growth Factor Therapy in Diabetic Macular Edema in the United States
  59. Vital Dyes in Vitreomacular Surgery
  60. Stargardt macular dystrophy and evolving therapies
  61. Real-world Outcomes of Anti–Vascular Endothelial Growth Factor Therapy in Neovascular Age-Related Macular Degeneration in the United States
  62. The acute and chronic effects of intravitreal anti-vascular endothelial growth factor injections on intraocular pressure: A review
  63. Comparison of Monthly vs Treat-and-Extend Regimens for Individuals With Macular Edema Who Respond Well to Anti–Vascular Endothelial Growth Factor Medications
  64. Pharmacotherapy of retinal disease with visual cycle modulators
  65. Gene therapy for inherited retinal and optic nerve degenerations
  66. Treatment Burden in Neovascular AMD:Visual Acuity Outcomes are Associated With Anti-VEGF Injection Frequency
  67. Gene therapy for age-related macular degeneration
  68. Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration
  69. LEAN SIX SIGMA TECHNIQUES TO IMPROVE OPHTHALMOLOGY CLINIC EFFICIENCY
  70. Induced pluripotent stem cell-based therapy for age-related macular degeneration
  71. Dual Antagonism of PDGF and VEGF in Neovascular Age-Related Macular Degeneration
  72. EFFICACY OF DEXAMETHASONE INTRAVITREAL IMPLANT FOR REFRACTORY MACULAR EDEMA CAUSED BY RETINAL VEIN OCCLUSION
  73. RANIBIZUMAB FOR DIABETIC MACULAR EDEMA REFRACTORY TO MULTIPLE PRIOR TREATMENTS
  74. Angiographic Cystoid Macular Edema and Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials
  75. Outcomes in Eyes with Retinal Angiomatous Proliferation in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
  76. Treatment strategies for refractory diabetic macular edema: switching anti-VEGF treatments, adopting corticosteroid-based treatments, and combination therapy
  77. Incidence, Risk Factors, and Timing of Elevated Intraocular Pressure After Intravitreal Triamcinolone Acetonide Injection for Macular Edema Secondary to Retinal Vein Occlusion
  78. Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials
  79. Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials
  80. Outcomes of Eyes with Lesions Composed of >50% Blood in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
  81. Efficacy of Intravitreal Ocriplasmin for Treatment of Vitreomacular Adhesion
  82. Sustained Delivery Fluocinolone Acetonide Vitreous Implants
  83. Comparison of Optical Coherence Tomography Assessments in the Comparison of Age-Related Macular Degeneration Treatments Trials
  84. The Prevalence and Incidence of Epiretinal Membranes in Eyes With Inactive Extramacular CMV Retinitis
  85. Sporadic Visual Acuity Loss in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT)
  86. VEGFAandVEGFR2Gene Polymorphisms and Response to Anti–Vascular Endothelial Growth Factor Therapy
  87. Treatment of diabetic macular edema with sustained-release glucocorticoids: intravitreal triamcinolone acetonide, dexamethasone implant, and fluocinolone acetonide implant
  88. Factors affecting visual outcomes in patients with diabetic macular edema treated with ranibizumab
  89. Pazopanib eye drops: a randomised trial in neovascular age-related macular degeneration
  90. Dexamethasone Intravitreal Implant in Combination with Laser Photocoagulation for the Treatment of Diffuse Diabetic Macular Edema
  91. Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials
  92. Exploratory Analysis of the Effect of Intravitreal Ranibizumab or Triamcinolone on Worsening of Diabetic Retinopathy in a Randomized Clinical Trial
  93. Comparison of Treatment Regimens for Cytomegalovirus Retinitis in Patients with AIDS in the Era of Highly Active Antiretroviral Therapy
  94. Twelve-Month Efficacy and Safety of 0.5 mg or 2.0 mg Ranibizumab in Patients with Subfoveal Neovascular Age-related Macular Degeneration
  95. Aqueous Levels of Fluocinolone Acetonide after Administration of Fluocinolone Acetonide Inserts or Fluocinolone Acetonide Implants
  96. Ranibizumab for Edema of the Macula in Diabetes Study
  97. Non-cytomegalovirus Ocular Opportunistic Infections in Patients With Acquired Immunodeficiency Syndrome
  98. Ranibizumab Versus Photodynamic Therapy for Presumed Ocular Histoplasmosis Syndrome
  99. Baseline Predictors for One-Year Visual Outcomes with Ranibizumab or Bevacizumab for Neovascular Age-related Macular Degeneration
  100. Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes
  101. Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration
  102. Incidence of Cytomegalovirus Retinitis in the Era of Highly Active Antiretroviral Therapy
  103. Impaired ocular blood flow regulation in patients with open-angle glaucoma and diabetes
  104. Evaluation of the United States Public Health Service Guidelines for Discontinuation of Anticytomegalovirus Therapy After Immune Recovery in Patients With Cytomegalovirus Retinitis
  105. Changes in Vision- and Health-Related Quality of Life in Patients with Diabetic Macular Edema Treated with Pegaptanib Sodium or Sham
  106. Primary Endpoint Results of a Phase II Study of Vascular Endothelial Growth Factor Trap-Eye in Wet Age-related Macular Degeneration
  107. A Phase 2/3, Multicenter, Randomized, Double-Masked, 2-Year Trial of Pegaptanib Sodium for the Treatment of Diabetic Macular Edema
  108. Association of Host Genetic Risk Factors With the Course of Cytomegalovirus Retinitis in Patients Infected With Human Immunodeficiency Virus
  109. Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
  110. Patient preferences in the treatment of diabetic retinopathy
  111. Long-term Benefit of Sustained-Delivery Fluocinolone Acetonide Vitreous Inserts for Diabetic Macular Edema
  112. Ranibizumab for Choroidal Neovascularization Secondary to Causes Other Than Age-Related Macular Degeneration: A Phase I Clinical Trial
  113. Two-Year Outcomes of the Ranibizumab for Edema of the mAcula in Diabetes (READ-2) Study
  114. Excess Mortality in Patients with AIDS in the Era of Highly Active Antiretroviral Therapy: Temporal Changes and Risk Factors
  115. Sustained Ocular Delivery of Fluocinolone Acetonide by an Intravitreal Insert
  116. Response to: Combined treatment of intravitreal bevacizumab and intravitreal triamcinolone in patients with retinal vein occlusion by Schroff et al.,
  117. Diabetic macular oedema: physical, physiological and molecular factors contribute to this pathological process
  118. Combined treatment of intravitreal bevacizumab and intravitreal triamcinolone in patients with retinal vein occlusion: 6 months of follow-up
  119. INTRAVITREAL BEVACIZUMAB FOR CHOROIDAL NEOVASCULARIZATION SECONDARY TO PRESUMED OCULAR HISTOPLASMOSIS SYNDROME
  120. Anti-vascular endothelial growth factor therapy for neovascular ocular diseases other than age-related macular degeneration
  121. Antivascular endothelial growth factor therapy for neovascular age-related macular degeneration
  122. Age-related macular degeneration and the aging eye
  123. Therapeutic effects of ranibizumab in neovascular age-related macular degeneration
  124. How the diabetic eye loses vision
  125. The Relationship Between Retrobulbar and Choroidal Hemodynamics in Non-Neovascular Age-Related Macular Degeneration
  126. Squalamine lactate for the treatment of age-related macular degeneration
  127. Ranibizumab
  128. SUSTAINED RESPONSE TO MULTIPLE INTRAVITREAL TRIAMCINOLONE ACETONIDE INJECTIONS IN A PATIENT WITH PREDOMINANTLY OCCULT CHOROIDAL NEOVASCULARIZATION
  129. Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-Related Macular Degeneration
  130. Corticosteroids as Antiangiogenic Agents
  131. Ranibizumab for Treatment of Neovascular Age-Related Macular Degeneration
  132. Retinal and Choroidal Blood Flow in Health and Disease
  133. ORAL ADMINISTRATION OF LUMIRACOXIB REDUCES CHOROIDAL NEOVASCULAR MEMBRANE DEVELOPMENT IN THE RAT LASER-TRAUMA MODEL
  134. HUMAN VITREOUS DISTRIBUTION OF LINEZOLID AFTER A SINGLE ORAL DOSE
  135. Anastomotic Vessels Remain Viable after Photodynamic Therapy in Primate Models of Choroidal Neovascularization
  136. Erratum
  137. New and classic insights into presumed ocular histoplasmosis syndrome and its treatment
  138. Current and future pharmacological intervention for diabetic retinopathy
  139. Future pharmacological treatment options for nonexudative and exudative age-related macular degeneration
  140. MV-6401, a potent photosensitizer: a review of the current state of photosensitizing agents for the treatment of exudative age-related macular degeneration
  141. Photodynamic therapy with PhotoPoint photosensitiser MV6401, indium chloride methyl pyropheophorbide, achieves selective closure of rat corneal neovascularisation and rabbit choriocapillaris
  142. Pharmacotherapy for diabetic retinopathy
  143. Macular pigment density and aging, assessed in the normal elderly and those with cataracts and age-related macular degeneration
  144. EVALUATION OF PHOTOPOINT PHOTOSENSITIZER MV6401, INDIUM CHLORIDE METHYL PYROPHEOPHORBIDE, AS A PHOTODYNAMIC THERAPY AGENT IN PRIMATE CHORIOCAPILLARIS AND LASER-INDUCED CHOROIDAL NEOVASCULARIZATION
  145. Corticosteroids in posterior segment disease: an update on new delivery systems and new indications
  146. Laser trabecular sclerosis for chronic hypotony after vitreoretinal surgery
  147. The Squirrel Monkey: Characterization of a New-World Primate Model of Experimental Choroidal Neovascularization and Comparison with the Macaque
  148. Diagnostic Imaging of Retinal Disease
  149. Current and Future Treatment Options for Nonexudative and Exudative Age-Related Macular Degeneration
  150. Squalamine Lactate Reduces Choroidal Neovascularization in a Laser-Injury Model in the Rat
  151. Diabetic Retinopathy and Diabetic Macular Edema: Pathophysiology, screening, and novel therapies
  152. Bacterial endophthalmitis prophylaxis
  153. Choroidal neovascular membrane inhibition in a laser treated rat model with intraocular sustained release triamcinolone acetonide microimplants
  154. The effects of dorzolamide on choroidal and retinal perfusion in non-exudative age related macular degeneration
  155. Leber congenital amaurosis associated with optic disk neovascularization and vitreous hemorrhage
  156. Recent advances in the treatment of exudative age-related macular degeneration, including transpupillary thermotherapy
  157. Proton therapy for exudative age-related macular degeneration: a randomized, sham-controlled clinical trial
  158. Ocular perfusion abnormalities in diabetes
  159. Novel approaches for retinal drug delivery
  160. An update on photodynamic therapy in age-related macular degeneration
  161. DIAGNOSTIC AND THERAPEUTIC CHALLENGES
  162. Intravitreal triamcinolone in subfoveal recurrence of choroidal neovascularisation after laser treatment in macular degeneration
  163. Choroidal perfusion perturbations in non-neovascular age related macular degeneration
  164. LOCALIZATION OF ROSE BENGAL, ALUMINUM PHTHALOCYANINE TETRASULFONATE, AND CHLORIN e6 IN THE RABBIT EYE
  165. Bacterial endophthalmitis prophylaxis for cataract surgery
  166. Presumed ocular histoplasmosis syndrome: update on epidemiology, pathogenesis, and photodynamic, antiangiogenic, and surgical therapies
  167. Relation between dietary intake, serum concentrations, and retinal concentrations of lutein and zeaxanthin in adults in a Midwest population
  168. Delayed suprachoroidal hemorrhage after glaucoma filtration procedures1 1The authors have no financial or proprietary interest in any aspect of this study.
  169. Evolving pathophysiological paradigms for age related macular degeneration
  170. Macular pigment optical density in a midwestern sample
  171. Ocular perfusion and age-related macular degeneration
  172. Intravitreal Triamcinolone Acetonide Inhibits Choroidal Neovascularization in a Laser-Treated Rat Model
  173. Anti-angiogenic therapy of proliferative diabetic retinopathy
  174. Potential therapeutic application of antisense oligonucleotides in the treatment of ocular diseases
  175. Changing therapeutic paradigms in CMV retinitis in AIDS
  176. Aging Affects the Retrobulbar Circulation Differently in Women and Men
  177. Endothelin-1-Mediated Retinal Artery Vasospasm and the Rabbit Electroretinogram
  178. MACULAR BUCKLING FOR RETINAL DETACHMENT DUE TO MACULAR HOLE IN HIGHLY MYOPIC EYES WITH POSTERIOR STAPHYLOMA
  179. Vasoprotection as neuroprotection for the optic nerve
  180. INTRAVITREAL TRIAMCINOLONE ACETONIDE IN EXUDATIVE AGE-RELATED MACULAR DEGENERATION
  181. Olestra Consumption Is Not Associated with Macular Pigment Optical Density in a Cross-Sectional Volunteer Sample in Indianapolis
  182. Update on acute and chronic endophthalmitis
  183. Changing therapeutic paradigms for exudative age-related macular degeneration: antiangiogenic agents and photodynamic therapy
  184. Corticosteroids as an Antiangiogenic Agent for Histoplasmosis-Related Subfoveal Choroidal Neovascularization
  185. Color Doppler imaging discloses reduced ocular blood flow velocities in nonexudative age-related macular degeneration
  186. Mitochondrial maculopathy: geographic atrophy of the macula in the MELAS associated A to G 3243 mitochondrial DNA point mutation
  187. Ginkgo biloba Extract Increases Ocular Blood Flow Velocity
  188. Progress in measurement of ocular blood flow and relevance to our understanding of glaucoma and age-related macular degeneration
  189. Comparison of intraocular to plasma HIV-1 viral burden in patients with cytomegalovirus retinitis
  190. Regulation of Retinal and Optic Nerve Blood Flow
  191. Age-Related Macular Degeneration
  192. THE USE OF DYE DILUTION CURVE ANALYSIS IN THE QUANTIFICATION OF INDOCYANINE GREEN ANGIOGRAMS OF THE HUMAN CHOROID
  193. Correspondence
  194. Repair of retinal detachments due to Herpes varicella-zoster virus retinitis
  195. Evolution of a full-thickness macular hole
  196. Radiation Therapy For Exudative Age-Related Macular Degeneration
  197. Talc Embolism: A Static Retinopathy
  198. Vascular Endothelial Growth Factor-Induced Retinal Permeability Is Mediated by Protein Kinase C In Vivo and Suppressed by an Orally Effective  -Isoform-Selective Inhibitor
  199. EXOGENOUS ASPERGILLUS NIGER ENDOPHTHALMITIS IN A PATIENT WITH A FILTERING BLEB
  200. Surgical Treatment of a Macular Hole Secondary to Accidental Laser Burn
  201. Blebitis, Early EndophthalmitS, and Late Endophthalmitis after Glaucoma-filtering Surgery
  202. Uveal lymphoid neoplasia: A clinical-pathologic correlation and review of the early form
  203. Subretinal Aspiration Biopsy of Ocular Lymphoma
  204. Acute Progressive Multifocal Best's Disease in a 61 -year-old Man
  205. Postvitrectomy Positioning Complicated by Ulnar Nerve Palsy
  206. Ocular Antimicrobial Therapy
  207. Endophthalmitis Following Glaucoma Filtering Surgery
  208. INTRAVITREAL TOXICITY OF DENTAL ADHESIVES IN THE RABBIT
  209. Serpiginous Choroiditis
  210. SEVERE PENETRATING EYE TRAUMA CAUSED BY FISH PICK ACCIDENTS
  211. Herpes Simplex Virus Corneal Dendrite
  212. Vitreous amyloidosis in familial amyloidotic polyneuropathy. Report of a case with the Val30Met transthyretin mutation
  213. Laser photodisruption of visible retinal artery emboli.
  214. Retinal artery occlusion in rabbit eyes using human atheroma
  215. Seronegative myasthenia gravis: A plasma factor inhibiting agonist-induced acetylcholine receptor function copurifies with IgM
  216. A susceptibility locus for multiple sclerosis is linked to the T cell receptor β chain complex
  217. PHOTOSENSITIZATION OF SINGLE-STRAND BREAKS IN pBR322 DNA BY ROSE BENGAL
  218. A simple method for DNA purification from peripheral blood
  219. Molecular Genotypes of the T-Cell Receptor Beta Chain in Families with Multiple Sclerosis
  220. PHOTOADDITION OF CHLORPROMAZINE TO GUANOSINE-5'-MONOPHOSPHATE