All Stories

  1. Strigolactone GR24 upregulates target genes of the cytoprotective transcription factor Nrf2 in skeletal muscle

    Article • F1000Research, November 2018, Faculty of 1000, Ltd.

    Dr Tarja Kokkola

  2. Strigolactone GR24 upregulates Nrf2 target genes and may protect against oxidative stress in skeletal muscle

    Article • F1000Research, September 2018, Faculty of 1000, Ltd.

    Dr Tarja Kokkola

  3. Structural properties for selective and efficient l-type amino acid transporter 1 (LAT1) mediated cellular uptake

    Article • International Journal of Pharmaceutics, June 2018, Elsevier

    Dr Tarja Kokkola

  4. Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes

    Article • Biochemical and Biophysical Research Communications, May 2018, Elsevier

    Dr Tarja Kokkola

  5. Suppressed heat shock protein response in the kidney of exercise-trained diabetic rats

    Article • Scandinavian Journal of Medicine and Science in Sports, March 2018, Wiley

    Dr Tarja Kokkola

  6. Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells

    Article • Scientific Reports, December 2017, Springer Science + Business Media

    Dr Tarja Kokkola

  7. Simvastatin induces insulin resistance in L6 skeletal muscle myotubes by suppressing insulin signaling, GLUT4 expression and GSK-3β phosphorylation

    Article • Biochemical and Biophysical Research Communications, November 2016, Elsevier

    Dr Tarja Kokkola

  8. Potent and selective N-(4-sulfamoylphenyl)thiourea-based GPR55 agonists

    Article • European Journal of Medicinal Chemistry, January 2016, Elsevier

    Dr Tarja Kokkola

  9. N-Acylethanolamines Bind to SIRT6

    Article • ChemBioChem, November 2015, Wiley

    Dr Tarja Kokkola

  10. Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells

    Article • PLoS ONE, November 2015, PLOS

    Dr Tarja Kokkola

  11. Transcriptomic Analysis of Human Primary Bronchial Epithelial Cells after Chloropicrin Treatment

    Article • Chemical Research in Toxicology, September 2015, American Chemical Society (ACS)

    Dr Tarja Kokkola

  12. BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses

    Article • ChemBioChem, August 2015, Wiley

    Dr Tarja Kokkola

  13. Virtual screening approach of sirtuin inhibitors results in two new scaffolds

    Article • European Journal of Pharmaceutical Sciences, August 2015, Elsevier

    Dr Tarja Kokkola

  14. Chroman-4-one- and Chromone-Based Sirtuin 2 Inhibitors with Antiproliferative Properties in Cancer Cells

    Article • Journal of Medicinal Chemistry, December 2014, American Chemical Society (ACS)

    Dr Tarja Kokkola

  15. Studying SIRT6 regulation using H3K56 based substrate and small molecules

    Article • European Journal of Pharmaceutical Sciences, October 2014, Elsevier

    Dr Tarja Kokkola

  16. AROS has a context-dependent effect on SIRT1

    Article • FEBS Letters, March 2014, Wiley

    Dr Tarja Kokkola

  17. Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress

    Article • Redox Biology, January 2014, Elsevier

    Dr Tarja Kokkola

  18. Screen of Pseudopeptidic Inhibitors of Human Sirtuins 1–3: Two Lead Compounds with Antiproliferative Effects in Cancer Cells

    Article • Journal of Medicinal Chemistry, August 2013, American Chemical Society (ACS)

    Dr Tarja Kokkola

  19. Somatostatin receptor 5 is palmitoylated by the interacting ZDHHC5 palmitoyltransferase

    Article • FEBS Letters, July 2011, Wiley

    Dr Tarja Kokkola

  20. Treatments with sodium selenate or doxycycline offset diabetes-induced perturbations of thioredoxin-1 levels and antioxidant capacity

    Article • Molecular and Cellular Biochemistry, January 2011, Springer Science + Business Media

    Dr Tarja Kokkola

  21. An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples

    Article • Free Radical Research, September 2010, Taylor & Francis

    Professor Fiorella Biasi, Dr Tarja Kokkola

  22. Inverse agonist exposure enhances ligand binding and G protein activation of the human MT1 melatonin receptor, but leads to receptor down-regulation

    Article • Journal of Pineal Research, October 2007, Wiley

    Dr Tarja Kokkola

  23. The functional role of cysteines adjacent to the NRY motif of the human MT1 melatonin receptor

    Article • Journal of Pineal Research, August 2005, Wiley

    Dr Tarja Kokkola

  24. Identification of WIN55212-3 as a competitive neutral antagonist of the human cannabinoid CB2receptor

    Article • British Journal of Pharmacology, July 2005, Wiley

    Dr Tarja Kokkola

  25. Article • BMC Cell Biology, January 2005, Springer Science + Business Media

    Dr Tarja Kokkola

  26. Important amino acids for the function of the human MT1 melatonin receptor

    Article • Biochemical Pharmacology, May 2003, Elsevier

    Dr Tarja Kokkola

  27. Mutagenesis of Human Mel1aMelatonin Receptor Expressed in Yeast Reveals Domains Important for Receptor Function

    Article • Biochemical and Biophysical Research Communications, August 1998, Elsevier

    Dr Tarja Kokkola

  28. TCDD alters melatonin metabolism in fish hepatocytes

    Article • Pathophysiology, June 1998, Elsevier

    Dr Tarja Kokkola

  29. Melatonin receptor genes

    Article • Annals of Medicine, January 1998, Taylor & Francis

    Dr Tarja Kokkola

  30. A rhodopsin-based model for melatonin recognition at its G protein-coupled receptor

    Article • European Journal of Pharmacology, May 1996, Elsevier

    Dr Tarja Kokkola

  31. Mechanism by which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) reduces circulating melatonin levels in the rat

    Article • Toxicology, February 1996, Elsevier

    Dr Tarja Kokkola

  32. Cholinergic signaling in the rat pineal gland

    Article • Cellular and Molecular Neurobiology, April 1995, Springer Science + Business Media

    Dr Tarja Kokkola