All Stories

  1. Hepatocyte Intrinsic Innate Antiviral Immunity against Hepatitis Delta Virus Infection: The Voices of Bona Fide Human Hepatocytes

    Article • Viruses, May 2024, MDPI AG

    Takeshi Saito

  2. Guiding Hepatic Differentiation of Pluripotent Stem Cells Using 3D Microfluidic Co-Cultures with Human Hepatocytes

    Article • Cells, August 2023, MDPI AG

    Takeshi Saito

  3. Long‐term cell fate and functional maintenance of human hepatocyte through stepwise culture configuration

    Article • The FASEB Journal, January 2023, Wiley

    Hyungjin Eoh, Takeshi Saito

  4. Development and characterization of secondary standards for nucleic acid amplification technology (NAAT) assays for detection of hepatitis E virus

    Article • Journal of Clinical Virology, December 2022, Elsevier

    Takeshi Saito

  5. Downregulation of SOCS1 increases interferon-induced ISGylation during differentiation of induced-pluripotent stem cells to hepatocytes

    Article • JHEP Reports, December 2022, Elsevier

    Takeshi Saito

  6. Reply to: Comments on: Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis

    Article • Transplant International, August 2022, Frontiers

    Takeshi Saito

  7. Loss of mitochondrial ATPase ATAD3A contributes to nonalcoholic fatty liver disease through accumulation of lipids and damaged mitochondria

    Article • Journal of Biological Chemistry, June 2022, Elsevier

    Takeshi Saito

  8. Differential IgG4-Producing Plasma Cell Infiltration in Non- and Post-Transplant Plasma Cell Hepatitis

    Article • Transplant International, March 2022, Frontiers

    Takeshi Saito

  9. Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3

    Article • Cell Reports, January 2022, Elsevier

    Takeshi Saito

  10. Infection courses, virological features and IFN-α responses of HBV genotypes in cell culture and animal models

    Article • Journal of Hepatology, December 2021, Elsevier

    Takeshi Saito

  11. Cholesterol-binding translocator protein TSPO regulates steatosis and bile acid synthesis in nonalcoholic fatty liver disease

    Article • iScience, May 2021, Elsevier

    Takeshi Saito

  12. A Case of Benign Hepatic Cyst with Supra-elevated Cyst Fluid Tumor Markers

    Article • Digestive Diseases and Sciences, January 2021, Springer Science + Business Media

    Takeshi Saito

  13. Suppression of hepatitis B virus through therapeutic activation of RIG-I and IRF3 signaling in hepatocytes

    Article • iScience, January 2021, Elsevier

    Takeshi Saito

  14. High Prevalence of Chronic Viral Hepatitis and Liver Fibrosis Among Mongols in Southern California

    Article • Digestive Diseases and Sciences, August 2020, Springer Science + Business Media

    Takeshi Saito

  15. Art of Making Artificial Liver: Depicting Human Liver Biology and Diseases in Mice

    Article • Seminars in Liver Disease, February 2020, Thieme Publishing Group

    Takeshi Saito

  16. Special Issue "IFN-Independent ISG Expression and its Role in Antiviral Cell-Intrinsic Innate Immunity"

    Article • Viruses, October 2019, MDPI AG

    Takeshi Saito

  17. Development of Capsular Fibrosis Beneath the Liver Surface in Humans and Mice

    Article • Hepatology, August 2019, Wiley

    Takeshi Saito

  18. Hepatic IFN-Induced Protein with Tetratricopeptide Repeats Regulation of HCV Infection

    Article • Journal of Interferon & Cytokine Research, March 2019, Mary Ann Liebert Inc

    Takeshi Saito

  19. Regulation of Hepatitis C Virus Infection by Cellular Retinoic Acid Binding Proteins through the Modulation of Lipid Droplet Abundance

    Article • Journal of Virology, February 2019, ASM Journals

    Takeshi Saito

  20. Dual modulation of human hepatic zonation via canonical and non-canonical Wnt pathways

    Article • Experimental & Molecular Medicine, December 2017, Springer Science + Business Media

    Takeshi Saito

  21. Reply

    Article • Gastroenterology, July 2017, Elsevier

    Takeshi Saito

  22. Detection of Occult Hepatitis C Virus Infection in Patients Who Achieved a Sustained Virologic Response to Direct-Acting Antiviral Agents for Recurrent Infection After Liver Transplantation

    Article • Gastroenterology, February 2017, Elsevier

    Takeshi Saito

  23. Hepatic angiosarcoma with clinical and histological features of Kasabach-Merritt syndrome

    Article • World Journal of Gastroenterology, January 2017, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Takeshi Saito

  24. Comparison of Demographic and Clinical Characteristics of Hispanic and Asian Chronic Hepatitis B Patients in Southern California

    Article • Journal of Clinical Gastroenterology, August 2016, Wolters Kluwer Health

    Takeshi Saito

  25. Organ system view of the hepatic innate immunity in HCV infection

    Article • Journal of Medical Virology, May 2016, Wiley

    Takeshi Saito

  26. Retinoid regulation of antiviral innate immunity in hepatocytes

    Article • Hepatology, January 2016, Wiley

    Takeshi Saito

  27. An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction

    Article • PLoS Pathogens, July 2015, PLOS

    Takeshi Saito

  28. Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1

    Article • Proceedings of the National Academy of Sciences, January 2014, Proceedings of the National Academy of Sciences

    Takeshi Saito

  29. Innate Immune Tolerance and the Role of Kupffer Cells in Differential Responses to Interferon Therapy Among Patients With HCV Genotype 1 Infection

    Article • Gastroenterology, February 2013, Elsevier

    Takeshi Saito

  30. Isolated arterioportal fistula presenting with variceal hemorrhage

    Article • World Journal of Gastroenterology, January 2013, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Takeshi Saito

  31. RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP

    Article • RNA, September 2010, Cold Spring Harbor Laboratory Press

    Takeshi Saito

  32. Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

    Article • Nature, July 2008, Springer Science + Business Media

    Michael Gale, Jr., Takeshi Saito

  33. Differential recognition of double-stranded RNA by RIG-I–like receptors in antiviral immunity: Figure 1.

    Article • Journal of Experimental Medicine, June 2008, Rockefeller University Press

    Takeshi Saito

  34. Regulation of innate immunity against hepatitis C virus infection

    Article • Hepatology Research, November 2007, Wiley

    Takeshi Saito

  35. Principles of intracellular viral recognition

    Article • Current Opinion in Immunology, February 2007, Elsevier

    Takeshi Saito

  36. Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

    Article • Proceedings of the National Academy of Sciences, January 2007, Proceedings of the National Academy of Sciences

    Takeshi Saito

  37. Viral and therapeutic control of IFN-β promoter stimulator 1 during hepatitis C virus infection

    Article • Proceedings of the National Academy of Sciences, April 2006, Proceedings of the National Academy of Sciences

    Takeshi Saito

  38. Translational enhancement of HCV RNA genotype 1b by 3′-untranslated and envelope 2 protein-coding sequences

    Article • Virology, February 2006, Elsevier

    Dr Kenichi Morikawa, Takeshi Saito

  39. Sequence analysis of PePHD within HCV E2 region and correlation with resistance of interferon therapy in Japanese patients infected with HCV genotypes 2a and 2b

    Article • The American Journal of Gastroenterology, June 2003, Nature

    Dr Kenichi Morikawa, Takeshi Saito

  40. A case of autoimmune pancreatitis responding to steroid therapy

    Article • Pancreatology, January 2002, Elsevier

    Takeshi Saito