Contact

All Stories

  1. Optimal Design of Neuroprotective Focal Brain Cooling Device Using Surrogate Model Approach

    Article • IEEE Transactions on Medical Robotics and Bionics, November 2020, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  2. A Palm-Sized Cryoprobe System With a Built-In Thermocouple and Its Application in an Animal Model of Epilepsy

    Article • IEEE Transactions on Biomedical Engineering, November 2019, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  3. Epileptic Seizure Suppression by Focal Brain Cooling With Recirculating Coolant Cooling System: Modeling and Simulation

    Article • IEEE Transactions on Neural Systems and Rehabilitation Engineering, February 2019, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  4. Cilostazol decreases duration of spreading depolarization and spreading ischemia after aneurysmal subarachnoid hemorrhage

    Article • Annals of Neurology, November 2018, Wiley

    D. Takao Inoue

  5. Thrombolysis with rt-PA under Rivaroxaban Anticoagulation in a Hypertensive Rat Model of Intraluminal Middle Cerebral Artery Occlusion

    Article • Journal of Stroke and Cerebrovascular Diseases, October 2018, Elsevier

    D. Takao Inoue

  6. Reduction of spike generation frequency by cooling in brain slices from rats and from patients with epilepsy

    Article • Journal of Cerebral Blood Flow & Metabolism, August 2018, SAGE Publications

    Dr. Sadahiro Nomura, D. Takao Inoue

  7. Detailed spectral profile analysis of electrocorticograms during freezing against penicillin-induced epileptiform discharges in the anesthetized rat

    Article • Epilepsy Research, July 2018, Elsevier

    D. Takao Inoue

  8. CFD-Based Design of Focal Brain Cooling System for Suppressing Epileptic Seizures

    Article • January 2018, Elsevier

    D. Takao Inoue

  9. Differential temperature sensitivity of synaptic and firing processes in a neural mass model of epileptic discharges explains heterogeneous response of experimental epilepsy to focal brain cooling

    Article • PLoS Computational Biology, October 2017, PLOS

    D. Takao Inoue

  10. Epidural focal brain cooling abolishes neocortical seizures in cats and non-human primates

    Article • Neuroscience Research, September 2017, Elsevier

    D. Takao Inoue

  11. Design of focal brain cooling system for suppressing epileptic seizures

    Article • July 2017, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  12. Effects of focal brain cooling on extracellular concentrations of neurotransmitters in patients with epilepsy

    Article • Epilepsia, February 2017, Wiley

    Dr. Sadahiro Nomura, D. Takao Inoue

  13. laser speckle subarachnoid hemorrhage cortical spreading depression

    Article • Journal of Neurosurgery, January 2017, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr. Sadahiro Nomura, D. Takao Inoue, Michiyasu Suzuki

  14. Continuous Monitoring of Spreading Depolarization and Cerebrovascular Autoregulation after Aneurysmal Subarachnoid Hemorrhage

    Article • Journal of Stroke and Cerebrovascular Diseases, October 2016, Elsevier

    D. Takao Inoue

  15. Neurocritical Care for Traumatic Brain Injury

    Article • Japanese Journal of Neurosurgery, January 2016, The Japanese Congress of Neurological Surgeons

    D. Takao Inoue

  16. The Palm-Sized Cryoprobe System Based on Refrigerant Expansion and Boiling and Its Application to an Animal Model of Epilepsy

    Article • IEEE Transactions on Biomedical Engineering, August 2015, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  17. Adverse Events after Unruptured Cerebral Aneurysm Treatment: A Single-center Experience with Clipping/Coil Embolization Combined Units

    Article • Journal of Stroke and Cerebrovascular Diseases, January 2015, Elsevier

    D. Takao Inoue

  18. Reliability of Laser Speckle Flow Imaging for Intraoperative Monitoring of Cerebral Blood Flow During Cerebrovascular Surgery: Comparison with Cerebral Blood Flow Measurement by Single Photon Emission Computed Tomography

    Article • World Neurosurgery, December 2014, Elsevier

    D. Takao Inoue

  19. Changes in glutamate concentration, glucose metabolism, and cerebral blood flow during focal brain cooling of the epileptogenic cortex in humans

    Article • Epilepsia, April 2014, Wiley

    Dr. Sadahiro Nomura, D. Takao Inoue

  20. Update on Intensive Neuromonitoring for Patients with Traumatic Brain Injury: A Review of the Literature and the Current Situation

    Article • Neurologia medico-chirurgica, January 2014, Japan Neurosurgical Society

    D. Takao Inoue

  21. Penicillin-induced epileptiform activity elevates focal brain temperature in anesthetized rats

    Article • Neuroscience Research, August 2013, Elsevier

    D. Takao Inoue

  22. Cooling Treatment Transiently Increases the Permeability of Brain Capillary Endothelial Cells Through Translocation of Claudin-5

    Article • Neurochemical Research, May 2013, Springer Science + Business Media

    D. Takao Inoue

  23. Neuroprotective effects of focal brain cooling on photochemically-induced cerebral infarction in rats: Analysis from a neurophysiological perspective

    Article • Brain Research, February 2013, Elsevier

    D. Takao Inoue

  24. Focal brain cooling terminates the faster frequency components of epileptic discharges induced by penicillin G in anesthetized rats

    Article • Clinical Neurophysiology, September 2012, Elsevier

    D. Takao Inoue

  25. Cooling of the epileptic focus suppresses seizures with minimal influence on neurologic functions

    Article • Epilepsia, January 2012, Wiley

    D. Takao Inoue

  26. Alterative treatment of intractable epilepsy with focal brain cooling - A review of our past studies -

    Article • October 2011, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  27. Development of a focal cerebral cooling system for the treatment of intractable epilepsy: An experimental study in cats and non-human primates

    Article • October 2011, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  28. Minimally-invasive epileptogenic focus detection using the subdural electrodes manipulated by the shape-memory-alloy thin wire

    Article • October 2011, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  29. The effect of focal brain cooling on epileptic discharges in rats: Frequency analysis of electroencephalography

    Article • October 2011, Institute of Electrical & Electronics Engineers (IEEE)

    D. Takao Inoue

  30. Discrimination between mothers’ infant- and adult-directed speech using hidden Markov models

    Article • Neuroscience Research, May 2011, Elsevier

    D. Takao Inoue

  31. Categorization of biologically significant objects, food and gender, in rhesus monkeys

    Article • Neuroscience Research, May 2008, Elsevier

    D. Takao Inoue

  32. Behavioral analysis of visual discrimination of sex in female macaque monkeys

    Article • International Congress Series, July 2007, Elsevier

    D. Takao Inoue

  33. Electrophysiological and behavioral evidences of the feeding-related neuronal processes in the orbitofrontal cortex

    Article • International Congress Series, July 2007, Elsevier

    D. Takao Inoue

  34. Brain strategy for energy saving and environmental preservation

    Article • International Congress Series, June 2006, Elsevier

    D. Takao Inoue

  35. Chemical impacts on higher brain functions

    Article • International Congress Series, August 2004, Elsevier

    D. Takao Inoue