All Stories

  1. Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

    Article • Journal of Virology, October 2017, ASM Journals

    Dr Takamasa Ueno, Dr Mark A Brockman

  2. Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

    Article • mBio, January 2016, ASM Journals

    Dr Takamasa Ueno, Dr Mark A Brockman

  3. A robust and scalable TCR-based reporter cell assay to measure HIV-1 Nef-mediated T cell immune evasion

    Article • Journal of Immunological Methods, November 2015, Elsevier

    Dr Takamasa Ueno, Dr Mark A Brockman

  4. Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

    Article • Journal of Virology, July 2015, ASM Journals

    Dr Takamasa Ueno, Dr Mark A Brockman

  5. Dynamic range of Nef-mediated evasion of HLA class II-restricted immune responses in early HIV-1 infection

    Article • Biochemical and Biophysical Research Communications, July 2015, Elsevier

    Dr Takamasa Ueno, Dr Mark A Brockman

  6. Association between a naturally arising polymorphism within a functional region of HIV-1 Nef and disease progression in chronic HIV-1 infection

    Article • Archives of Virology, June 2015, Springer Science + Business Media

    Dr Takamasa Ueno

  7. Modest Attenuation of HIV-1 Vpu Alleles Derived from Elite Controller Plasma

    Article • PLoS ONE, March 2015, PLOS

    Dr Takamasa Ueno

  8. Revealing the peptide presenting process of human leukocyte antigen through the analysis of fluctuation

    Article • BIOPHYSICS, January 2015, Biophysical Society of Japan

    Dr Takamasa Ueno

  9. Cross-reactivity analysis of T cell receptors specific for overlapping HIV-1 Nef epitopes of different lengths

    Article • Microbes and Infection, April 2014, Elsevier

    Dr Takamasa Ueno

  10. Naturally-arising amino acid polymorphisms of HIV-1 Nef that differentially modulate downregulation of HLA-A and HLA-B molecules

    Article • Retrovirology, September 2013, Springer Science + Business Media

    Dr Mark A Brockman, Dr Takamasa Ueno

  11. CD8+ T Cell Cross-Reactivity Profiles and HIV-1 Immune Escape towards an HLA-B35-Restricted Immunodominant Nef Epitope

    Article • PLoS ONE, June 2013, PLOS

    Dr Takamasa Ueno

  12. Dynamic range of Nef functions in chronic HIV-1 infection

    Article • Virology, May 2013, Elsevier

    Dr Mark A Brockman, Dr Takamasa Ueno

  13. Attenuation of multiple Nef functions in HIV-1 elite controllers

    Article • Retrovirology, January 2013, Springer Science + Business Media

    Dr Mark A Brockman, Dr Takamasa Ueno

  14. Brockman, M.A., et al., Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants? Viruses 2012, 4, 1711-1730

    Article • Viruses, October 2012, MDPI AG

    Dr Mark A Brockman, Dr Takamasa Ueno

  15. Human Leukocyte Antigen (HLA) Class I Down-Regulation by Human Immunodeficiency Virus Type 1 Negative Factor (HIV-1 Nef): What Might We Learn From Natural Sequence Variants?

    Article • Viruses, September 2012, MDPI AG

    Dr Mark A Brockman, Dr Takamasa Ueno

  16. Minor contribution of HLA class I-associated selective pressure to the variability of HIV-1 accessory protein Vpu

    Article • Biochemical and Biophysical Research Communications, May 2012, Elsevier

    Dr Takamasa Ueno

  17. The Identification of a Small Molecule Compound That Reduces HIV-1 Nef-Mediated Viral Infectivity Enhancement

    Article • PLoS ONE, November 2011, PLOS

    Dr Takamasa Ueno

  18. Impairment of viral replication capacity by nef alleles from HIV elite controllers

    Article • Retrovirology, October 2011, Springer Science + Business Media

    Dr Mark A Brockman, Dr Takamasa Ueno

  19. Effects of naturally-arising HIV Nef mutations on cytotoxic T lymphocyte recognition and Nef's functionality in primary macrophages

    Article • Retrovirology, January 2011, Springer Science + Business Media

    Dr Takamasa Ueno

  20. Naturally arising HIV-1 Nef variants conferring escape from cytotoxic T lymphocytes influence viral entry co-receptor expression and susceptibility to superinfection

    Article • Biochemical and Biophysical Research Communications, December 2010, Elsevier

    Dr Takamasa Ueno

  21. Failure of Effector Function of Human CD8+ T Cells in NOD/SCID/JAK3−/− Immunodeficient Mice Transplanted with Human CD34+ Hematopoietic Stem Cells

    Article • PLoS ONE, October 2010, PLOS

    Dr Takamasa Ueno

  22. Dynamic interplay between viral adaptation and immune recognition during HIV-1 infection

    Article • Protein & Cell, June 2010, Springer Science + Business Media

    Dr Takamasa Ueno

  23. Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbsN-glycosylation of a cytokine receptor Fms

    Article • Journal of Cellular Physiology, November 2009, Wiley

    Dr Takamasa Ueno

  24. Determination of a major histocompatibility complex class I restricting simian immunodeficiency virus Gag241???249 epitope

    Article • AIDS, May 2008, Wolters Kluwer Health

    Dr Takamasa Ueno, Dr Tetsuo Tsukamoto

  25. Reconstitution of anti-HIV effector functions of primary human CD8 T?lymphocytes by transfer of HIV-specific ???TCR genes

    Article • European Journal of Immunology, December 2004, Wiley

    Dr Takamasa Ueno

  26. HLA class I-restricted recognition of an HIV-derived epitope peptide by a human T cell receptorα chain having a Vδ1 variable segment

    Article • European Journal of Immunology, October 2003, Wiley

    Dr Takamasa Ueno

  27. Inhibition of telomerase by linear-chain fatty acids: a structural analysis

    Article • Biochemical Journal, October 2002, Portland Press Ltd.

    Dr Takamasa Ueno

  28. Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target

    Article • FEBS Letters, July 2002, Wiley

    Dr Takamasa Ueno

  29. Structural analysis of chick ephrin-A2 by function-blocking and non-blocking monoclonal antibodies

    Article • Biochemical and Biophysical Research Communications, July 2002, Elsevier

    Dr Takamasa Ueno

  30. The role of hepatitis B virus-specific memory CD8 T cells in the control of viral replication

    Article • Journal of Hepatology, January 2002, Elsevier

    Dr Takamasa Ueno

  31. Inhibition of the Hepatitis C Virus NS3 Protease Activity by Fv Fragment of Antibody 8D4

    Article • Biochemical and Biophysical Research Communications, February 2001, Elsevier

    Dr Takamasa Ueno

  32. A recurrent large Alu-mediated deletion in the hypoxanthine phosphoribosyltransferase (HPRT1) gene associated with Lesch-Nyhan syndrome

    Article • Human Mutation, January 2001, Wiley

    Dr Takamasa Ueno

  33. The biochemical mode of inhibition of DNA polymerase β by α-rubromycin

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, October 2000, Elsevier

    Dr Takamasa Ueno

  34. Inhibition of Human Telomerase by Rubromycins:  Implication of Spiroketal System of the Compounds as an Active Moiety

    Article • Biochemistry, May 2000, American Chemical Society (ACS)

    Dr Takamasa Ueno

  35. Structure-Activity Relationship of Orally Potent Tripeptide-Based HIV Protease Inhibitors Containing Hydroxymethylcarbonyl Isostere.

    Article • Chemical and Pharmaceutical Bulletin, January 2000, Pharmaceutical Society of Japan

    Dr Takamasa Ueno

  36. Suppressive Effect of Topically Applied CX-659S, a Novel Diaminouracil Derivative, on the Contact Hypersensitivity Reaction in Various Animal Models

    Article • International Archives of Allergy and Immunology, January 2000, Karger Publishers

    Dr Takamasa Ueno

  37. Structure−Activity Relationship of Small-Sized HIV Protease Inhibitors Containing Allophenylnorstatine

    Article • Journal of Medicinal Chemistry, May 1999, American Chemical Society (ACS)

    Dr Takamasa Ueno

  38. A phase I trial of the pharmacokinetics, toxicity, and activity of KNI-272, an inhibitor of HIV-1 protease, in patients with AIDS or symptomatic HIV infection

    Article • Antiviral Research, February 1999, Elsevier

    Dr Takamasa Ueno

  39. DEVELOPMENT OF FLUOROQUINOLONE RESISTANCE AND MUTATIONS INVOLVING GyrA AND ParC PROTEINS AMONG NEISSERIA GONORRHOEAE ISOLATES IN JAPAN

    Article • The Journal of Urology, June 1998, Elsevier

    Dr Takamasa Ueno

  40. Flagellar filament elongation can be impaired by mutations in the hook protein FlgE ofSalmonella typhimurium: a possible role of the hook as a passage for the anti-sigma factor FlgM

    Article • Molecular Microbiology, March 1998, Wiley

    Dr Takamasa Ueno

  41. Comparative Enzymatic Study of HIV-1 Reverse Transcriptase Resistant to 2‘,3‘-Dideoxynucleotide Analogs Using the Single-Nucleotide Incorporation Assay

    Article • Biochemistry, February 1997, American Chemical Society (ACS)

    Dr Takamasa Ueno

  42. Current Status of the Development of HIV Protease Inhibitors and Their Clinical Potential

    Article • Clinical Immunotherapeutics, December 1995, Springer Science + Business Media

    Dr Takamasa Ueno

  43. Domain Structures of the MS Ring Component Protein (FliF) of the Flagellar Basal Body of Salmonella typhimurium

    Article • Journal of Molecular Biology, February 1994, Elsevier

    Dr Takamasa Ueno, Kenji Oosawa

  44. M ring, S ring and proximal rod of the flagellar basal body of Salmonella typhimurium are composed of subunits of a single protein, FliF

    Article • Journal of Molecular Biology, October 1992, Elsevier

    Dr Takamasa Ueno, Kenji Oosawa