All Stories

  1. Cytochrome P450 168A1 from Pseudomonas aeruginosa is involved in the hydroxylation of biologically relevant fatty acids

    Article • PLoS ONE, March 2022, PLOS

    Professor Steven L Kelly

  2. The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51

    Article • Antimicrobial Agents and Chemotherapy, May 2017, ASM Journals

    Professor Steven L Kelly

  3. The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme

    Article • Antimicrobial Agents and Chemotherapy, May 2016, ASM Journals

    Professor Steven L Kelly

  4. In VitroBiochemical Study of CYP51-Mediated Azole Resistance in Aspergillus fumigatus

    Article • Antimicrobial Agents and Chemotherapy, October 2015, ASM Journals

    Professor Steven L Kelly, Professor Diane Kelly

  5. Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51)

    Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

    Professor Steven L Kelly

  6. Novel Substrate Specificity and Temperature-Sensitive Activity of Mycosphaerella graminicola CYP51 Supported by the Native NADPH Cytochrome P450 Reductase

    Article • Applied and Environmental Microbiology, March 2015, ASM Journals

    Professor Diane Kelly, Professor Steven L Kelly

  7. The Clinical Candidate VT-1161 Is a Highly Potent Inhibitor of Candida albicans CYP51 but Fails To Bind the Human Enzyme

    Article • Antimicrobial Agents and Chemotherapy, September 2014, ASM Journals

    Professor Diane Kelly, Professor Steven L Kelly

  8. Clotrimazole as a Potent Agent for Treating the Oomycete Fish Pathogen Saprolegnia parasitica through Inhibition of Sterol 14α-Demethylase (CYP51)

    Article • Applied and Environmental Microbiology, August 2014, ASM Journals

    Professor Diane Kelly, Professor Steven L Kelly

  9. Prothioconazole and Prothioconazole-Desthio Activities against Candida albicans Sterol 14-α-Demethylase

    Article • Applied and Environmental Microbiology, December 2012, ASM Journals

    Professor Steven L Kelly

  10. Azole Affinity of Sterol 14α-Demethylase (CYP51) Enzymes from Candida albicans and Homo sapiens

    Article • Antimicrobial Agents and Chemotherapy, December 2012, ASM Journals

    Professor Steven L Kelly