All Stories

  1. Molecular mechanics and quantum chemical calculations unveil the combating effect of baicalein on human islet amyloid polypeptide aggregates

    Article • Molecular Simulation, August 2019, Taylor & Francis

    Srinivasan ekambaram, Mr VENKATARAMANAN SWAMINATHAN

  2. Comparative binding of kaempferol and kaempferide on inhibiting the aggregate formation of mutant (G85R) SOD1 protein in familial amyotrophic lateral sclerosis: A quantum chemical and molecular mechanics study

    Article • BioFactors, September 2018, Wiley

    Srinivasan ekambaram

  3. Brain-Related Disease Study

    Article • International Journal of Biological Macromolecules, February 2018, Elsevier

    Srinivasan ekambaram

  4. Cysteine to Serine Conversion at 111th Position Renders the Disaggregation and Retains the Stabilization of Detrimental SOD1 A4V Mutant Against Amyotrophic Lateral Sclerosis in Human—A Discrete Molecular Dynamics Study

    Article • Cell Biochemistry and Biophysics, September 2017, Springer Science + Business Media

    Srinivasan ekambaram

  5. Probing the inhibitory activity of epigallocatechin-gallate on toxic aggregates of mutant (L84F) SOD1 protein through geometry based sampling and steered molecular dynamics

    Article • Journal of Molecular Graphics and Modelling, June 2017, Elsevier

    Srinivasan ekambaram

  6. Exploring the cause of aggregation and reduced Zn binding affinity by G85R mutation in SOD1 rendering amyotrophic lateral sclerosis

    Article • Proteins Structure Function and Bioinformatics, April 2017, Wiley

    Srinivasan ekambaram

  7. A theoretical study on Zn binding loop mutants instigating destabilization and metal binding loss in human SOD1 protein

    Article • Journal of Molecular Modeling, March 2017, Springer Science + Business Media

    Srinivasan ekambaram

  8. Computational investigation of the human SOD1 mutant, Cys146Arg, that directs familial amyotrophic lateral sclerosis

    Article • Molecular BioSystems, January 2017, Royal Society of Chemistry

    Srinivasan ekambaram

  9. Computational simulation analysis on human SOD1 mutant (H80R) exposes the structural destabilization and the deviation of Zn binding that directs familial amyotrophic lateral sclerosis

    Article • Journal of Biomolecular Structure and Dynamics, September 2016, Taylor & Francis

    Srinivasan ekambaram

  10. Computational investigation of curcumin, a natural polyphenol that inhibits the destabilization and the aggregation of human SOD1 mutant (Ala4Val)

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Srinivasan ekambaram