All Stories

  1. Loss of growth hormone–mediated signal transducer and activator of transcription 5 (STAT5) signaling in mice results in insulin sensitivity with obesity

    Article • The FASEB Journal, February 2019, Wiley

    Sof Andrikopoulos, David Waxman, Yash Chhabra

  2. A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in themdxDystrophic Mouse

    Article • Mediators of Inflammation, January 2017, Hindawi Publishing Corporation

    Sof Andrikopoulos

  3. Identification of ABCC8 as a contributory gene to impaired early-phase insulin secretion in NZO mice

    Article • October 2015, Bioscientifica

    Sof Andrikopoulos

  4. Contribution of the hypothalamus and gut to weight gain susceptibility and resistance in mice

    Article • May 2015, Bioscientifica

    Sof Andrikopoulos

  5. Improving Glucose Tolerance by Reducing Weight Gain in a Polygenic Obese Mouse Model: Use of a High Protein Diet

    Article • Hormone and Metabolic Research, October 2014, Thieme Publishing Group

    Sof Andrikopoulos

  6. Systemic VEGF-A Neutralization Ameliorates Diet-Induced Metabolic Dysfunction

    Article • Diabetes, July 2014, American Diabetes Association

    Sof Andrikopoulos

  7. High-Fat-Fed Obese Glutathione Peroxidase 1-Deficient Mice Exhibit Defective Insulin Secretion but Protection from Hepatic Steatosis and Liver Damage

    Article • Antioxidants & Redox Signaling, May 2014, Mary Ann Liebert Inc

    Sof Andrikopoulos

  8. Hope and fear for new classes of type 2 diabetes drugs: is there preclinical evidence that incretin-based therapies alter pancreatic morphology?

    Article • January 2014, Bioscientifica

    Sof Andrikopoulos

  9. Receptor for advanced glycation end products is a regulator or glucagon production

    Article • Obesity Research & Clinical Practice, December 2013, Elsevier

    Sof Andrikopoulos

  10. Exercise-induced muscle glucose uptake in mice with graded, muscle-specific GLUT-4 deletion

    Article • Physiological Reports, August 2013, Wiley

    Sof Andrikopoulos

  11. Glucose homeostasis can be differentially modulated by varying individual components of a western diet

    Article • The Journal of Nutritional Biochemistry, July 2013, Elsevier

    Sof Andrikopoulos

  12. A novel mechanism regulating insulin secretion involving Herpud1 in mice

    Article • Diabetologia, April 2013, Springer Science + Business Media

    Sof Andrikopoulos

  13. Neprilysin Deficiency Protects Against Fat-Induced Insulin Secretory Dysfunction by Maintaining Calcium Influx

    Article • Diabetes, April 2013, American Diabetes Association

    Sof Andrikopoulos

  14. First Phase Insulin Secretion and Type 2 Diabetes

    Article • Current Molecular Medicine, January 2013, Bentham Science Publishers

    Sof Andrikopoulos

  15. First Phase Insulin Secretion and Type 2 Diabetes

    Article • Current Molecular Medicine, December 2012, Bentham Science Publishers

    Sof Andrikopoulos

  16. First Phase Insulin Secretion and Type 2 Diabetes

    Article • Current Molecular Medicine, December 2012, Bentham Science Publishers

    Sof Andrikopoulos

  17. Response to Comment on: Visinoni et al. The Role of Liver Fructose-1,6-Bisphosphatase in Regulating Appetite and Adiposity. Diabetes 2012;61:1122–1132

    Article • Diabetes, November 2012, American Diabetes Association

    Sof Andrikopoulos

  18. The liver

    Article • Adipocyte, October 2012, Taylor & Francis

    Sof Andrikopoulos

  19. Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes

    Article • Nature, September 2012, Springer Science + Business Media

    Sof Andrikopoulos

  20. Methazolamide Is a New Hepatic Insulin Sensitizer That Lowers Blood Glucose In Vivo

    Article • Diabetes, July 2012, American Diabetes Association

    Sof Andrikopoulos

  21. High Passage MIN6 Cells Have Impaired Insulin Secretion with Impaired Glucose and Lipid Oxidation

    Article • PLoS ONE, July 2012, PLOS

    Sof Andrikopoulos

  22. The Role of Liver Fructose-1,6-Bisphosphatase in Regulating Appetite and Adiposity

    Article • Diabetes, April 2012, American Diabetes Association

    Sof Andrikopoulos

  23. The Nuclear Receptor, Nor-1, Markedly Increases Type II Oxidative Muscle Fibers and Resistance to Fatigue

    Article • Molecular Endocrinology, March 2012, Endocrine Society

    Sof Andrikopoulos

  24. Deficiency in Interferon-γ Results in Reduced Body Weight and Better Glucose Tolerance in Mice

    Article • Endocrinology, October 2011, Endocrine Society

    Sof Andrikopoulos

  25. Advanced Glycation End Products Are Direct Modulators of β-Cell Function

    Article • Diabetes, September 2011, American Diabetes Association

    Sof Andrikopoulos

  26. Targeted reduction of advanced glycation improves renal function in obesity

    Article • Kidney International, July 2011, Elsevier

    Sof Andrikopoulos

  27. A primary defect in glucose production alone cannot induce glucose intolerance without defects in insulin secretion

    Article • Journal of Endocrinology, June 2011, Bioscientifica

    Sof Andrikopoulos

  28. Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes

    Article • Diabetologia, April 2011, Springer Science + Business Media

    Sof Andrikopoulos

  29. The New Zealand obese mouse model of obesity insulin resistance and poor breeding performance: evaluation of ovarian structure and function

    Article • Journal of Endocrinology, March 2011, Bioscientifica

    Sof Andrikopoulos

  30. Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes

    Article • Diabetologia, February 2011, Springer Science + Business Media

    Sof Andrikopoulos

  31. Liver-Specific Suppressor of Cytokine Signaling-3 Deletion in Mice Enhances Hepatic Insulin Sensitivity and Lipogenesis Resulting in Fatty Liver and Obesity

    Article • Hepatology, November 2010, Wolters Kluwer Health

    Sof Andrikopoulos

  32. Methods for Enhancing Ring Closing Metathesis Yield in Peptides: Synthesis of a Dicarba Human Growth Hormone Fragment

    Article • International Journal of Peptide Research and Therapeutics, June 2010, Springer Science + Business Media

    Sof Andrikopoulos

  33. T-Cell Protein Tyrosine Phosphatase Attenuates STAT3 and Insulin Signaling in the Liver to Regulate Gluconeogenesis

    Article • Diabetes, May 2010, American Diabetes Association

    Sof Andrikopoulos

  34. Obesity and Type 2 diabetes: Slow down!—Can metabolic deceleration protect the islet beta cell from excess nutrient-induced damage?

    Article • Molecular and Cellular Endocrinology, March 2010, Elsevier

    Sof Andrikopoulos

  35. The Deletion Variant of Nicotinamide Nucleotide Transhydrogenase (Nnt) Does Not Affect Insulin Secretion or Glucose Tolerance

    Article • Endocrinology, January 2010, Endocrine Society

    Sof Andrikopoulos

  36. Use of a Temporary “Solubilizing” Peptide Tag for the Fmoc Solid-Phase Synthesis of Human Insulin Glargine via Use of Regioselective Disulfide Bond Formation

    Article • Bioconjugate Chemistry, June 2009, American Chemical Society (ACS)

    Sof Andrikopoulos

  37. Fructose-1,6-Bisphosphatase Overexpression in Pancreatic β-Cells Results in Reduced Insulin Secretion

    Article • Diabetes, July 2008, American Diabetes Association

    Sof Andrikopoulos

  38. Insulin may have a role to play in protecting beta cells from deterioration in diabetes. Reply to Del Parigi A [letter]

    Article • Diabetologia, April 2008, Springer Science + Business Media

    Sof Andrikopoulos

  39. Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth

    Article • The Journal of Pathology, April 2008, Wiley

    Sof Andrikopoulos

  40. Too much of a good thing: why it is bad to stimulate the beta cell to secrete insulin

    Article • Diabetologia, February 2008, Springer Science + Business Media

    Sof Andrikopoulos

  41. Increased nicotinamide nucleotide transhydrogenase levels predispose to insulin hypersecretion in a mouse strain susceptible to diabetes

    Article • Diabetologia, October 2007, Springer Science + Business Media

    Sof Andrikopoulos

  42. The New Zealand Obese Mouse

    Article • April 2007, Taylor & Francis

    Sof Andrikopoulos

  43. In vivo quantification of fat content in mice using the Hologic QDR 4500A densitometer

    Article • Obesity Research & Clinical Practice, January 2007, Elsevier

    Sof Andrikopoulos

  44. Tumor necrosis factor α-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling

    Article • Cell Metabolism, December 2006, Elsevier

    Sof Andrikopoulos

  45. Modulation of central leptin sensitivity and energy balance in a rat model of diet‐induced obesity

    Article • Diabetes Obesity and Metabolism, August 2006, Wiley

    Sof Andrikopoulos

  46. Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice

    Article • Endocrinology, August 2006, Endocrine Society

    Sof Andrikopoulos

  47. Expression of Human Fructose-1,6-Bisphosphatase in the Liver of Transgenic Mice Results in Increased Glycerol Gluconeogenesis

    Article • Endocrinology, June 2006, Endocrine Society

    Sof Andrikopoulos

  48. The influence of genetic background on the induction of oxidative stress and impaired insulin secretion in mouse islets

    Article • Diabetologia, March 2006, Springer Science + Business Media

    Sof Andrikopoulos

  49. Amylin in the Periphery II: An Updated Mini-Review

    Article • The Scientific World JOURNAL, January 2006, Hindawi Publishing Corporation

    Sof Andrikopoulos

  50. Differential effect of inbred mouse strain (C57BL/6, DBA/2, 129T2) on insulin secretory function in response to a high fat diet

    Article • Journal of Endocrinology, October 2005, Bioscientifica

    Sof Andrikopoulos

  51. Investigational agents that protect pancreatic islet β-cells from failure

    Article • Expert Opinion on Investigational Drugs, September 2005, Informa Healthcare

    Sof Andrikopoulos

  52. Post-Exercise Insulin Sensitivity and Glucose Disposal are Unaffected by Intramuscular Triglyceride (IMTG) Levels

    Article • Medicine & Science in Sports & Exercise, May 2005, Wolters Kluwer Health

    Sof Andrikopoulos

  53. Post-Exercise Insulin Sensitivity and Glucose Disposal are Unaffected by Intramuscular Triglyceride (IMTG) Levels

    Article • Medicine & Science in Sports & Exercise, May 2005, Wolters Kluwer Health

    Sof Andrikopoulos

  54. Elevated SNAP-25 is associated with fatty acid-induced impairment of mouse islet function

    Article • Biochemical and Biophysical Research Communications, April 2004, Elsevier

    Sof Andrikopoulos

  55. Improved Islet Morphology after Blockade of the Renin- Angiotensin System in the ZDF Rat

    Article • Diabetes, April 2004, American Diabetes Association

    Sof Andrikopoulos

  56. Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide

    Article • AJP Endocrinology and Metabolism, October 2003, American Physiological Society

    Sof Andrikopoulos

  57. Peripheral insulin resistance develops in transgenic rats overexpressing phosphoenolpyruvate carboxykinase in the kidney

    Article • Diabetologia, October 2003, Springer Science + Business Media

    Sof Andrikopoulos

  58. Proteoglycans synthesized and secreted by pancreatic islet β-cells bind amylin

    Article • Archives of Biochemistry and Biophysics, May 2003, Elsevier

    Sof Andrikopoulos

  59. Interleukin-6 gene expression is increased in insulin-resistant rat skeletal muscle following insulin stimulation

    Article • Biochemical and Biophysical Research Communications, March 2003, Elsevier

    Sof Andrikopoulos

  60. Increased Dietary Fat Promotes Islet Amyloid Formation and β-Cell Secretory Dysfunction in a Transgenic Mouse Model of Islet Amyloid

    Article • Diabetes, February 2003, American Diabetes Association

    Sof Andrikopoulos

  61. The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets

    Article • Archives of Biochemistry and Biophysics, September 2002, Elsevier

    Sof Andrikopoulos

  62. Comparison of Insulin Secretory Function in Two Mouse Models with Different Susceptibility to β-Cell Failure

    Article • Endocrinology, June 2002, Endocrine Society

    Sof Andrikopoulos

  63. Effects of free fatty acids on insulin secretion in obesity

    Article • Obesity Reviews, April 2002, Wiley

    Sof Andrikopoulos

  64. Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice.

    Article • Diabetes, February 2001, American Diabetes Association

    Sof Andrikopoulos

  65. beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.

    Article • Diabetes, December 2000, American Diabetes Association

    Sof Andrikopoulos

  66. Oophorectomy promotes islet amyloid formation in a transgenic mouse model of Type II diabetes

    Article • Diabetologia, October 2000, Springer Science + Business Media

    Sof Andrikopoulos

  67. Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid.

    Article • Diabetes, October 1999, American Diabetes Association

    Sof Andrikopoulos

  68. Islet amyloid: a long-recognized but underappreciated pathological feature of type 2 diabetes.

    Article • Diabetes, February 1999, American Diabetes Association

    Sof Andrikopoulos

  69. Reduced amylin release is a characteristic of impaired glucose tolerance and type 2 diabetes in Japanese Americans.

    Article • Diabetes, April 1998, American Diabetes Association

    Sof Andrikopoulos

  70. Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand obese mouse: An acquired defect

    Article • Metabolism, May 1996, Elsevier

    Sof Andrikopoulos

  71. Understanding the pathogenesis of type 2 diabetes: can we get off the metabolic merry‐go‐rounds?

    Article • Australian and New Zealand Journal of Medicine, December 1995, Wiley

    Sof Andrikopoulos

  72. The biochemical basis of increased hepatic glucose production in a mouse model of type 2 (non-insulin-dependent) diabetes mellitus

    Article • Diabetologia, December 1995, Springer Science + Business Media

    Sof Andrikopoulos

  73. Defects in liver and muscle glycogen metabolism in neonatal and adult New Zealand Obese mice

    Article • Metabolism, October 1995, Elsevier

    Sof Andrikopoulos

  74. Impaired glucose tolerance and increased weight gain in transgenic rats overexpressing a non-insulin-responsive phosphoenolpyruvate carboxykinase gene.

    Article • Molecular Endocrinology, October 1995, Endocrine Society

    Sof Andrikopoulos

  75. Impaired regulation of hepatic fructose-1,6-bisphosphatase in the New Zealand obese mouse model of NIDDM

    Article • Diabetes, December 1993, American Diabetes Association

    Sof Andrikopoulos

  76. Impaired Regulation of Hepatic Fructose-1,6-Bisphosphatase in the New Zealand Obese Mouse Model of NIDDM

    Article • Diabetes, December 1993, American Diabetes Association

    Sof Andrikopoulos

  77. Impaired suppression of gluconeogenesis induced by overexpression of a noninsulin-responsive phosphoenolpyruvate carboxykinase gene.

    Article • Molecular Endocrinology, November 1993, Endocrine Society

    Sof Andrikopoulos