All Stories

  1. RNA-directed activation of cytoplasmic dynein-1 in reconstituted transport RNPs

    Article • eLife, June 2018, eLife

    Simon Bullock

  2. A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons

    Article • Current Biology, March 2018, Elsevier

    Simon Bullock

  3. Lissencephaly-1 is a context-dependent regulator of the human dynein complex

    Article • eLife, April 2017, eLife

    Simon Bullock

  4. SnapShot: Subcellular mRNA Localization

    Article • Cell, March 2017, Elsevier

    Simon Bullock

  5. DYNC1H1 mutations associated with neurological diseases compromise processivity of dynein–dynactin–cargo adaptor complexes

    Article • Proceedings of the National Academy of Sciences, February 2017, Proceedings of the National Academy of Sciences

    Simon Bullock

  6. DYNC1H1mutations associated with neurological diseases compromise processivity of dynein-dynactin-cargo adaptor complexes

    Article • December 2016, Cold Spring Harbor Laboratory Press

    Simon Bullock

  7. Augmenting CRISPR applications in Drosophila with tRNA-flanked sgRNAs

    Article • Nature Methods, September 2016, Nature

    Simon Bullock

  8. A simple method for imaging axonal transport in aging neurons using the adult Drosophila wing

    Article • Nature Protocols, August 2016, Nature

    Simon Bullock

  9. Expansion of the CRISPR toolbox in an animal with tRNA-flanked Cas9 and Cpf1 gRNAs

    Article • March 2016, Cold Spring Harbor Laboratory Press

    Simon Bullock

  10. Creating Heritable Mutations in Drosophila with CRISPR-Cas9

    Article • January 2016, Springer Science + Business Media

    Simon Bullock

  11. Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adultDrosophilaneurons

    Article • Journal of Cell Science, November 2015, The Company of Biologists

    Simon Bullock

  12. Safeguarding gene drive experiments in the laboratory

    Article • Science, July 2015, American Association for the Advancement of Science

    Simon Bullock, Anthony James

  13. Systematic Evaluation of Drosophila CRISPR Tools Reveals Safe and Robust Alternatives to Autonomous Gene Drives in Basic Research

    Article • G3 Genes Genomes Genetics, May 2015, Genetics Society of America

    Simon Bullock

  14. CRISPR with independent transgenes is a safe and robust alternative to autonomous gene drives in basic research

    Article • April 2015, Cold Spring Harbor Laboratory Press

    Simon Bullock

  15. Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in Drosophila

    Article • Proceedings of the National Academy of Sciences, July 2014, Proceedings of the National Academy of Sciences

    Simon Bullock

  16. In vitro reconstitution of a highly processive recombinant human dynein complex

    Article • The EMBO Journal, July 2014, EMBO

    Simon Bullock

  17. The influence of dynein processivity control, MAPs, and microtubule ends on directional movement of a localising mRNA

    Article • eLife, April 2014, eLife

    Simon Bullock

  18. An optimized CRISPR/Cas toolbox for efficient germline and somatic genome engineering in Drosophila

    Article • March 2014, Cold Spring Harbor Laboratory Press

    Simon Bullock

  19. Dynein Associates with oskar mRNPs and Is Required For Their Efficient Net Plus-End Localization in Drosophila Oocytes

    Article • PLoS ONE, November 2013, PLOS

    Simon Bullock

  20. Lissencephaly-1 promotes the recruitment of dynein and dynactin to transported mRNAs

    Article • The Journal of Cell Biology, August 2013, Rockefeller University Press

    Simon Bullock

  21. Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to coordinate recruitment of cargos to dynein

    Article • Genes & Development, May 2013, Cold Spring Harbor Laboratory Press

    Simon Bullock

  22. Single-molecule assays reveal that RNA localization signals regulate dynein–dynactin copy number on individual transcript cargoes

    Article • Nature Cell Biology, February 2012, Springer Science + Business Media

    Simon Bullock

  23. Messengers, motors and mysteries: sorting of eukaryotic mRNAs by cytoskeletal transport: Figure 1

    Article • Biochemical Society Transactions, October 2011, Portland Press Ltd.

    Simon Bullock

  24. Bicaudal-D Regulates Fragile X Mental Retardation Protein Levels, Motility, and Function during Neuronal Morphogenesis

    Article • Current Biology, August 2010, Elsevier

    Simon Bullock

  25. A′-form RNA helices are required for cytoplasmic mRNA transport in Drosophila

    Article • Nature Structural & Molecular Biology, May 2010, Springer Science + Business Media

    Simon Bullock

  26. Bicaudal-D binds clathrin heavy chain to promote its transport and augments synaptic vesicle recycling

    Article • The EMBO Journal, January 2010, Springer Science + Business Media

    Simon Bullock

  27. Subcellular mRNA Localization in Animal Cells and Why It Matters

    Article • Science, November 2009, American Association for the Advancement of Science

    Simon Bullock

  28. Egalitarian is a selective RNA-binding protein linking mRNA localization signals to the dynein motor

    Article • Genes & Development, June 2009, Cold Spring Harbor Laboratory Press

    Simon Bullock

  29. Translocation of mRNAs by molecular motors: Think complex?

    Article • Seminars in Cell and Developmental Biology, April 2007, Elsevier

    Simon Bullock

  30. Guidance of Bidirectional Motor Complexes by mRNA Cargoes through Control of Dynein Number and Activity

    Article • Current Biology, July 2006, Elsevier

    Simon Bullock

  31. inscuteable mRNA Localization Is Dynein-Dependent and Regulates Apicobasal Polarity and Spindle Length in Drosophila Neuroblasts

    Article • Current Biology, November 2004, Elsevier

    Simon Bullock

  32. Specific modification of heparan sulphate is required for normal cerebral cortical development

    Article • Mechanisms of Development, December 2003, Elsevier

    Simon Bullock

  33. Growth and Early Postimplantation Defects in Mice Deficient for the Bromodomain-Containing Protein Brd4

    Article • Molecular and Cellular Biology, June 2002, ASM Journals

    Simon Bullock

  34. Cell polarity: Oskar seeks PARtner for a stable relationship

    Article • Nature, May 2002, Nature

    Simon Bullock

  35. Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis

    Article • Nature, December 2001, Springer Science + Business Media

    Simon Bullock

  36. The Molecular Phenotype of Heparan Sulfate in theHs2st -/- Mutant Mouse

    Article • Journal of Biological Chemistry, July 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Simon Bullock

  37. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase

    Article • Genes & Development, June 1998, Cold Spring Harbor Laboratory Press

    Simon Bullock