Contact

All Stories

  1. Non-pungent capsiate enhances longevity and healthspan in Caenorhabditis elegans via transient receptor potential (TRP) channels

    Article • Food & Function, January 2025, Royal Society of Chemistry

    PhD Shinkichi Tawata

  2. p21-Activated kinase 1 (PAK1) in aging and longevity: An overview

    Article • Ageing Research Reviews, November 2021, Elsevier

    PhD Shinkichi Tawata

  3. Chemical composition and pharmacological properties of Macaranga‐type Pacific propolis: A review

    Article • Phytotherapy Research, August 2020, Wiley

    PhD Shinkichi Tawata

  4. Cytotoxic and anti-inflammatory resorcinol and alkylbenzoquinone derivatives from the leaves of Ardisia sieboldii

    Article • Zeitschrift für Naturforschung C, November 2019, De Gruyter

    PhD Shinkichi Tawata

  5. A computational approach to explore and identify potential herbal inhibitors for the p21-activated kinase 1 (PAK1)

    Article • Journal of Biomolecular Structure and Dynamics, September 2019, Taylor & Francis

    Mohammad Halim, PhD Shinkichi Tawata

  6. Anti-Inflammatory, Anti-Diabetic, and Anti-Alzheimer’s Effects of Prenylated Flavonoids from Okinawa Propolis: An Investigation by Experimental and Computational Studies

    Article • Molecules, September 2018, MDPI AG

    PhD Shinkichi Tawata

  7. Cytotoxic Desulfated Saponin from Holothuria atra Predicted to Have High Binding Affinity to the Oncogenic Kinase PAK1: A Combined In Vitro and In Silico Study

    Article • Scientia Pharmaceutica, August 2018, MDPI AG

    PhD Shinkichi Tawata

  8. Hair Growth Promoting and Anticancer Effects of p21-activated kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia zerumbet

    Article • Molecules, January 2017, MDPI AG

    PhD Shinkichi Tawata

  9. 1,2,3-Triazolyl ester of Ketorolac: A “Click Chemistry”-based highly potent PAK1-blocking cancer-killer

    Article • European Journal of Medicinal Chemistry, January 2017, Elsevier

    PhD Shinkichi Tawata

  10. 1,2,3-Triazolyl esterization of PAK1-blocking propolis ingredients, artepillin C (ARC) and caffeic acid (CA), for boosting their anti-cancer/anti-PAK1 activities along with cell-permeability

    Article • Drug Discoveries & Therapeutics, January 2017, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    PhD Shinkichi Tawata

  11. Frondoside A from sea cucumber and nymphaeols from Okinawa propolis: Natural anti-cancer agents that selectively inhibit PAK1 in vitro

    Article • Drug Discoveries & Therapeutics, January 2017, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    PhD Shinkichi Tawata

  12. Effect of Okinawa Propolis on PAK1 Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells

    Article • Journal of Agricultural and Food Chemistry, July 2016, American Chemical Society (ACS)

    PhD Shinkichi Tawata

  13. The Chemistry and Biological Activities of Mimosine: A Review

    Article • Phytotherapy Research, May 2016, Wiley

    PhD Shinkichi Tawata

  14. 5,6-Dehydrokawain fromAlpinia zerumbetpromotes osteoblastic MC3T3-E1 cell differentiation

    Article • Bioscience Biotechnology and Biochemistry, March 2016, Taylor & Francis

    PhD Shinkichi Tawata

  15. Artepillin C and Other Herbal PAK1-blockers: Effects on Hair Cell Proliferation and Related PAK1-dependent Biological Function in Cell Culture

    Article • Phytotherapy Research, November 2015, Wiley

    PhD Shinkichi Tawata

  16. Anti-Oxidant, Anti-Aging, and Anti-Melanogenic Properties of the Essential Oils from Two Varieties of Alpinia zerumbet

    Article • Molecules, September 2015, MDPI AG

    PhD Shinkichi Tawata

  17. Insecticidal and Nematicidal Activities of Novel Mimosine Derivatives

    Article • Molecules, September 2015, MDPI AG

    PhD Shinkichi Tawata

  18. Mimosine Dipeptide Enantiomsers: Improved Inhibitors against Melanogenesis and Cyclooxygenase

    Article • Molecules, August 2015, MDPI AG

    PhD Shinkichi Tawata

  19. Combination of immunoprecipitation (IP)-ATP_Glo kinase assay and melanogenesis for the assessment of potent and safe PAK1-blockers in cell culture

    Article • Drug Discoveries & Therapeutics, January 2015, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    PhD Shinkichi Tawata

  20. Hispidin and related herbal compounds from Alpinia zerumbet inhibit both PAK1-dependent melanogenesis in melanocytes and reactive oxygen species (ROS) production in adipocytes

    Article • Drug Discoveries & Therapeutics, January 2015, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    PhD Shinkichi Tawata

  21. Anti-Obesity Effects of Hispidin and Alpinia zerumbet Bioactives in 3T3-L1 Adipocytes

    Article • Molecules, October 2014, MDPI AG

    PhD Shinkichi Tawata

  22. Several herbal compounds in Okinawa plants directly inhibit the oncogenic/aging kinase PAK1

    Article • Drug Discoveries & Therapeutics, January 2014, International Research and Cooperation Association for Bio & Socio-Sciences Advancement (IRCA-BSSA)

    PhD Shinkichi Tawata

  23. Utilization of Pineapple Waste: A Review

    Article • Journal of Food Science and Technology Nepal, June 2013, Nepal Journals Online (NepJOL)

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  24. Significant Longevity-Extending Effects of Alpinia zerumbet Leaf Extract on the Life Span of Caenorhabditis elegans

    Article • Bioscience Biotechnology and Biochemistry, January 2013, Japan Society for Bioscience, Biotechnology, and Agrochemistry

    PhD Shinkichi Tawata

  25. Allelopathic interference of sweet potato with cogongrass and relevant species

    Article • Plant Ecology, October 2012, Springer Science + Business Media

    PhD Shinkichi Tawata

  26. Effect of Alpinia zerumbet components on antioxidant and skin diseases-related enzymes

    Article • BMC Complementary and Alternative Medicine, July 2012, Springer Science + Business Media

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  27. Synthesis and Antiangiogenic Activity of Novel Gambogic Acid Derivatives

    Article • Molecules, May 2012, MDPI AG

    PhD Shinkichi Tawata

  28. Antioxidant Activity of Phenolic Rich Fraction Obtained from Convolvulus arvensis L. Leaves Grown in Egypt

    Article • Asian Journal of Crop Science, January 2012, Science Alert

    PhD Shinkichi Tawata

  29. Advanced glycation end products inhibitors from Alpinia zerumbet rhizomes

    Article • Food Chemistry, December 2011, Elsevier

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  30. Solid-Phase Synthesis of Mimosine Tetrapeptides and Their Inhibitory Activities on Neuraminidase and Tyrosinase

    Article • Journal of Agricultural and Food Chemistry, November 2011, American Chemical Society (ACS)

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  31. Antioxidant, Antimicrobial, 15-LOX, and AGEs Inhibitions by Pineapple Stem Waste

    Article • Journal of Food Science, November 2011, Wiley

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  32. Antioxidant phenolic compounds from Smilax sebeana Miq.

    Article • LWT, September 2011, Elsevier

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  33. Effect of Extraction and Drying Methods on the Contents of Kava Pyrones and Phenolic Compounds in Alpinia zerumbet Leaves

    Article • Asian Journal of Plant Sciences, August 2011, Science Alert

    PhD Shinkichi Tawata

  34. HIV-1 Integrase and Neuraminidase Inhibitors from Alpinia zerumbet

    Article • Journal of Agricultural and Food Chemistry, February 2011, American Chemical Society (ACS)

    Dr Atul Upadhyay, PhD Shinkichi Tawata

  35. Isolation and identification of antioxidant and hyaluronidase inhibitory compounds fromFicus microcarpaL. fil. bark

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, March 2010, Taylor & Francis

    PhD Shinkichi Tawata

  36. Variation of weed-suppressing potential of Vietnamese rice cultivars against barnyardgrass (Echinochloa crus-galli) in laboratory, greenhouse and field screenings

    Article • Journal of Plant Interactions, September 2009, Taylor & Francis

    PhD Shinkichi Tawata

  37. Biological activity and composition of extract from aerial root ofFicus microcarpaL. fil.

    Article • International Journal of Food Science & Technology, February 2009, Wiley

    PhD Shinkichi Tawata

  38. Allelochemicals of barnyardgrass-infested soil and their activities on crops and weeds

    Article • Weed Biology and Management, December 2008, Wiley

    PhD Shinkichi Tawata

  39. Evaluation of antioxidant and antibacterial activities of Ficus microcarpa L. fil. extract

    Article • Food Control, October 2008, Elsevier

    PhD Shinkichi Tawata

  40. Chemical composition and antioxidant, antibacterial and antifungal activities of the essential oils from Bidens pilosa Linn. var. Radiata

    Article • Food Control, April 2008, Elsevier

    PhD Shinkichi Tawata

  41. MMP-13 Inhibitory Activity of Thirteen Selected Plant Species from Okinawa

    Article • International Journal of Pharmacology, March 2008, Science Alert

    PhD Shinkichi Tawata

  42. Total utilization of tropical plants Leucaena leucocephala and Alpinia zerumbet

    Article • Journal of Pesticide Science, January 2008, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  43. Toward deeper understanding of bioactive molecules for innovative crop protection

    Article • Journal of Pesticide Science, January 2008, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  44. Comparative efficaciesin vitroof antibacterial, fungicidal, antioxidant, and herbicidal activities of momilatones A and B

    Article • Journal of Plant Interactions, December 2007, Taylor & Francis

    PhD Shinkichi Tawata

  45. Efficacy of extracting solvents to chemical components of kava (Piper methysticum) roots

    Article • Journal of Natural Medicines, November 2007, Springer Science + Business Media

    PhD Shinkichi Tawata

  46. Allelopathy for weed management in sustainable agriculture.

    Article • CABI Reviews, September 2007, CABI Publishing

    PhD Shinkichi Tawata

  47. Herbicidal and fungicidal activities and identification of potential phytotoxins from Bidens pilosa L. var. radiata Scherff

    Article • Weed Biology and Management, June 2007, Wiley

    PhD Shinkichi Tawata

  48. Changes in essential oil, kava pyrones and total phenolics of Alpinia zerumbet (Pers.) B.L. Burtt. & R.M. Sm. leaves exposed to copper sulphate

    Article • Environmental and Experimental Botany, April 2007, Elsevier

    PhD Shinkichi Tawata

  49. Antioxidant activity and contents of essential oil and phenolic compounds in flowers and seeds of Alpinia zerumbet (Pers.) B.L. Burtt. & R.M. Sm

    Article • Food Chemistry, January 2007, Elsevier

    PhD Shinkichi Tawata

  50. Essential oils, kava pyrones and phenolic compounds from leaves and rhizomes of Alpinia zerumbet (Pers.) B.L. Burtt. & R.M. Sm. and their antioxidant activity

    Article • Food Chemistry, January 2007, Elsevier

    PhD Shinkichi Tawata

  51. Weed suppression by Passiflora edulis and its potential allelochemicals

    Article • Weed Research, August 2006, Wiley

    PhD Shinkichi Tawata

  52. Identification of Phytotoxic Substances from Early Growth of Barnyard Grass (Echinochloa crusgalli) Root Exudates

    Article • Journal of Chemical Ecology, April 2006, Springer Science + Business Media

    PhD Shinkichi Tawata

  53. Mimosine in Leucaena as a potent bio-herbicide

    Article • Agronomy for Sustainable Development, April 2006, Springer Science + Business Media

    PhD Shinkichi Tawata

  54. Current status of biological control of paddy weeds in Vietnam

    Article • Weed Biology and Management, March 2006, Wiley

    PhD Shinkichi Tawata

  55. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum)

    Article • Journal of Agricultural and Food Chemistry, February 2006, American Chemical Society (ACS)

    PhD Shinkichi Tawata

  56. Purification and characterization of extracellular cysteine protease inhibitor, ECPI-2, from Chlorella sp.

    Article • Journal of Bioscience and Bioengineering, February 2006, Elsevier

    PhD Shinkichi Tawata

  57. Production of angiotensin I-converting enzyme inhibitory peptides from soybean protein with Monascus purpureus acid proteinase

    Article • Process Biochemistry, May 2005, Elsevier

    PhD Shinkichi Tawata

  58. An alkaline protease inhibitor from Aspergillus oryzae W-1

    Article • Nippon Shokuhin Kagaku Kogaku Kaishi, January 2003, Japanese Society for Food Science and Technology

    PhD Shinkichi Tawata

  59. An Antihemolysin from Pineapple Stem.

    Article • Nippon Shokuhin Kagaku Kogaku Kaishi, January 2003, Japanese Society for Food Science and Technology

    PhD Shinkichi Tawata

  60. Angiotensin I-Converting Enzyme Inhibitory Peptides Isolated from Tofuyo Fermented Soybean Food

    Article • Bioscience Biotechnology and Biochemistry, January 2003, Taylor & Francis

    PhD Shinkichi Tawata

  61. Purification and Some Properties of an Alkaline Protease Inhibitor-Inactivating-Enzyme from Aspergillus oryzae W-1

    Article • Nippon Shokuhin Kagaku Kogaku Kaishi, January 2003, Japanese Society for Food Science and Technology

    PhD Shinkichi Tawata

  62. Syntheses and Biological Activities of Pyranyl-substituted Cinnamates

    Article • Bioscience Biotechnology and Biochemistry, January 2001, Taylor & Francis

    PhD Shinkichi Tawata

  63. Inhibitory Effects ofAlpinia speciosaK. SCHUM on the Porphyrin Photooxidative Reaction

    Article • The Journal of Dermatology, May 2000, Wiley

    PhD Shinkichi Tawata

  64. Synthesis and Fungitoxic Activity of N-Cinnamoyl-α-Amino Acid Esters

    Article • Journal of Pesticide Science, January 2000, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  65. Disintegration of uncooked rice by carboxymethyl cellulase from Sporotrichum sp. HG-I

    Article • Journal of Bioscience and Bioengineering, January 1999, Elsevier

    PhD Shinkichi Tawata

  66. Purification and Characterization of Feruloyl Esterase from Aspergillus awamori.

    Article • Food Science and Technology Research, January 1999, Japanese Society for Food Science and Technology

    PhD Shinkichi Tawata

  67. Purification and Characterization of Intracellular Cysteine Protease Inhibitor from Chlorella sp..

    Article • Food Science and Technology Research, January 1999, Japanese Society for Food Science and Technology

    PhD Shinkichi Tawata

  68. Synthesis and Fungicidal Activity of New 6-Alkyl-2-alkylamino-4H-1, 3, 2-benzodioxaphosphorin 2-Sulfides

    Article • Journal of Pesticide Science, January 1998, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  69. Purification and some properties of a thermostable xylanase from thermophilic fungus strain HG-1

    Article • Journal of Fermentation and Bioengineering, January 1997, Elsevier

    PhD Shinkichi Tawata

  70. Synthesis and Fungicidal Activity of 6-Alkyl Six-membered Cyclic Thiophosphates

    Article • Bioscience Biotechnology and Biochemistry, January 1997, Taylor & Francis

    PhD Shinkichi Tawata

  71. Syntheses and Biological Activities of Dihydro-5,6-dehydrokawain Derivatives

    Article • Bioscience Biotechnology and Biochemistry, January 1996, Taylor & Francis

    PhD Shinkichi Tawata

  72. Synthesis and Antifungal Activity of Cinnamic Acid Esters

    Article • Bioscience Biotechnology and Biochemistry, January 1996, Taylor & Francis

    PhD Shinkichi Tawata

  73. Purification and Properties of a Ribonuclease from a Species of the GenusMonascus

    Article • Bioscience Biotechnology and Biochemistry, January 1995, Taylor & Francis

    PhD Shinkichi Tawata

  74. Synthesis and Fungicidal Activity of New Six-membered Cyclic Phosphates

    Article • Journal of Pesticide Science, January 1995, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  75. Synthesis and Fungicidal Activity of New 1, 3, 2-Oxazaphospholidine 2-Sulfides

    Article • Journal of Pesticide Science, January 1994, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  76. Mimosine, a nonprotein amino acid, inhibits growth and enzyme systems in Tribolium castaneum

    Article • Pesticide Biochemistry and Physiology, January 1991, Elsevier

    PhD Shinkichi Tawata

  77. Inhibitory effect of flavonoids on DNA-dependent DNA and RNA polymerases

    Article • Cellular and Molecular Life Sciences, October 1988, Springer Science + Business Media

    PhD Shinkichi Tawata

  78. Cytotoxicity of plant flavonoids against HeLa cells

    Article • Phytochemistry, January 1988, Elsevier

    PhD Shinkichi Tawata

  79. Antibacterial activity of flavonoids against Staphylococcus epidermidis, a skin bacterium.

    Article • Agricultural and Biological Chemistry, January 1987, Taylor & Francis

    PhD Shinkichi Tawata

  80. Antibacterial activity and mode of action of plant flavonoids against Proteus vulgaris and Staphylococcus aureus

    Article • Phytochemistry, January 1987, Elsevier

    PhD Shinkichi Tawata

  81. Antibacterial Activity of Flavonoids againstStaphylococcus epidermidis, a Skin Bacterium

    Article • Agricultural and Biological Chemistry, January 1987, Taylor & Francis

    PhD Shinkichi Tawata

  82. [Z]-4-alkylidene-1,3,2-benzodioxaphosphorinane 2-oxides from stereospecific cyclization of 2-alkylketophenyl phosphonates and phosphates

    Article • Bioorganic Chemistry, December 1982, Elsevier

    PhD Shinkichi Tawata

  83. Insecticidal 4-alkylidene-1,3,2-benzodioxaphosphorinane derivatives

    Article • Journal of Agricultural and Food Chemistry, January 1982, American Chemical Society (ACS)

    PhD Shinkichi Tawata

  84. Article • NIPPON KAGAKU KAISHI, January 1981, The Chemical Society of Japan

    PhD Shinkichi Tawata

  85. Synthesis and Chemical Properties of Insecticidal 2-Alkoxy-4-alkyl-1,3,2-oxazaphospholidine 2-Sulfides Derived from Optically Active Amino Acids

    Article • Agricultural and Biological Chemistry, July 1980, Taylor & Francis

    PhD Shinkichi Tawata

  86. Studies on oxazaphospholidines with pesticidal activities. III. Synthesis and chemical properties of insecticidal 2-alkoxy-4-alkyl-1,3,2-oxazaphospholidine 2-sulfides derived from optically active amino acids.

    Article • Agricultural and Biological Chemistry, January 1980, Taylor & Francis

    PhD Shinkichi Tawata

  87. Novel Insecticidal Five-Membered Cyclic Phosphoramidothionates Derived from L-Amino Acids

    Article • Journal of Pesticide Science, January 1978, Pesticide Science Society of Japan

    PhD Shinkichi Tawata

  88. Synthesis and Insecticidal Activities of Five-membered Cyclic Phosphoramidates and Phosphoramidothiolates

    Article • Journal of Pesticide Science, January 1978, Pesticide Science Society of Japan

    PhD Shinkichi Tawata