All Stories

  1. Antimalarial drug discovery targeting apical membrane antigen 1

    Article • MedChemComm, January 2017, Royal Society of Chemistry

    Dr Shane M Devine

  2. VCP746, a novel A1adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model

    Article • Clinical and Experimental Pharmacology and Physiology, September 2016, Wiley

    Dr Shane M Devine

  3. Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials

    Article • Journal of Molecular Recognition, January 2016, Wiley

    Dr Shane M Devine, Professor Martin J Scanlon

  4. Promiscuous 2-Aminothiazoles (PrATs): A Frequent Hitting Scaffold

    Article • Journal of Medicinal Chemistry, February 2015, American Chemical Society (ACS)

    Dr Shane M Devine, Professor Martin J Scanlon

  5. Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK

    Article • ChemistryOpen, November 2014, Wiley

    Dr Shane M Devine

  6. Ligand-Induced Conformational Change of Plasmodium falciparum AMA1 Detected Using 19F NMR

    Article • Journal of Medicinal Chemistry, August 2014, American Chemical Society (ACS)

    Dr Shane M Devine, Professor Martin J Scanlon

  7. Molecular Mechanisms of Bitopic Ligand Engagement with the M1 Muscarinic Acetylcholine Receptor

    Article • Journal of Biological Chemistry, July 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Shane M Devine

  8. Design, synthesis and evaluation of N6-substituted 2-aminoadenosine-5′-N-methylcarboxamides as A3 adenosine receptor agonists

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Dr Shane M Devine

  9. A critical evaluation of pyrrolo[2,3-d]pyrimidine-4-amines as Plasmodium falciparum apical membrane antigen 1 (AMA1) inhibitors

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Dr Shane M Devine, Professor Martin J Scanlon

  10. Reverse Engineering of the Selective Agonist TBPB Unveils Both Orthosteric and Allosteric Modes of Action at the M1 Muscarinic Acetylcholine Receptor

    Article • Molecular Pharmacology, June 2013, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Dr Shane M Devine

  11. An Allosteric Modulator of the Adenosine A1 Receptor Improves Cardiac Function Following Ischaemia in Murine Isolated Hearts

    Article • Pharmaceuticals, April 2013, MDPI AG

    Dr Shane M Devine

  12. Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Dr Shane M Devine, Professor Martin J Scanlon

  13. Synthesis and Pharmacological Evaluation of Dual Acting Antioxidant A2A Adenosine Receptor Agonists

    Article • Journal of Medicinal Chemistry, March 2012, American Chemical Society (ACS)

    Dr Shane M Devine

  14. Synthesis and Characterization of Novel 2-Amino-3-benzoylthiophene Derivatives as Biased Allosteric Agonists and Modulators of the Adenosine A1 Receptor

    Article • Journal of Medicinal Chemistry, February 2012, American Chemical Society (ACS)

    Dr Shane M Devine, Professor Jonathan White

  15. Synthesis and Utility of 2‐Halo‐O6‐(benzotriazol‐1‐yl)‐Functionalized Purine Nucleosides

    Article • European Journal of Organic Chemistry, December 2010, Wiley

    Dr Shane M Devine

  16. Richter cyclization and co-cyclization reactions of triazene-masked diazonium ions

    Article • Tetrahedron Letters, December 2010, Elsevier

    Dr Shane M Devine

  17. A Novel Highly Selective Adenosine A1 Receptor Agonist VCP28 Reduces Ischemia Injury in a Cardiac Cell Line and Ischemia–Reperfusion Injury in Isolated Rat Hearts at Concentrations That Do Not Affect Heart Rate

    Article • Journal of Cardiovascular Pharmacology, September 2010, Wolters Kluwer Health

    Dr Shane M Devine

  18. Synthesis and evaluation of new N6-substituted adenosine-5′-N-methylcarboxamides as A3 adenosine receptor agonists

    Article • Bioorganic & Medicinal Chemistry, May 2010, Elsevier

    Dr Shane M Devine

  19. Linear and convergent approaches to 2-substituted adenosine-5′-N-alkylcarboxamides

    Article • Tetrahedron, October 2009, Elsevier

    Dr Shane M Devine

  20. An efficient convergent synthesis of adenosine-5′-N-alkyluronamides

    Article • Tetrahedron, February 2008, Elsevier

    Dr Shane M Devine

  21. Dual acting antioxidant A1 adenosine receptor agonists

    Article • Bioorganic & Medicinal Chemistry Letters, October 2007, Elsevier

    Dr Shane M Devine

  22. Novel annulated products from aminonaphthyridinones

    Article • Tetrahedron, March 2006, Elsevier

    Dr Shane M Devine

  23. Synthesis and Reactivity of Some Imidazo‐, Triazolo‐ and Tetrazolo‐Isoquinoline Derivatives.

    Article • ChemInform, November 2004, Wiley

    Dr Shane M Devine

  24. Synthesis and reactivity of some imidazo‐, triazolo‐ and tetrazolo‐isoquinoline derivatives

    Article • Journal of Heterocyclic Chemistry, July 2004, Wiley

    Dr Shane M Devine

  25. A Convenient Procedure for Indirect Oxidation of Aromatic Methyl Groups to Aldehydes and Carboxylic Acids.

    Article • ChemInform, March 2004, Wiley

    Dr Shane M Devine

  26. A CONVENIENT PROCEDURE FOR INDIRECT OXIDATION OF AROMATIC METHYL GROUPS TO ALDEHYDES AND CARBOXYLIC ACIDS

    Article • Organic Preparations and Procedures International, December 2003, Taylor & Francis

    Dr Shane M Devine