All Stories

  1. Multi-omic rejuvenation and life span extension on exposure to youthful circulation

    Article • Nature Aging, July 2023, Springer Science + Business Media

    Prof Sergey E Dmitriev

  2. Monitoring integrated stress response in liveDrosophila

    Article • July 2023, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  3. Human Tissues Exhibit Diverse Composition of Translation Machinery

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Prof Sergey E Dmitriev

  4. Human tissues exhibit diverse composition of translation machinery

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  5. Relocalization of Translation Termination and Ribosome Recycling Factors to Stress Granules Coincides with Elevated Stop-Codon Readthrough and Reinitiation Rates upon Oxidative Stress

    Article • Cells, January 2023, MDPI AG

    Prof Sergey E Dmitriev

  6. Longevity and rejuvenation effects of cell reprogramming are decoupled from loss of somatic identity

    Article • December 2022, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  7. Enteroviruses Manipulate the Unfolded Protein Response through Multifaceted Deregulation of the Ire1-Xbp1 Pathway

    Article • Viruses, November 2022, MDPI AG

    Prof Sergey E Dmitriev

  8. Robust expression of transgenes inDrosophila melanogaster

    Article • October 2022, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  9. In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan

    Article • Nature Aging, May 2022, Springer Science + Business Media

    Prof Sergey E Dmitriev

  10. Ribo-Seq and RNA-Seq of TMA46 (DFRP1) and GIR2 (DFRP2) knockout yeast strains

    Article • F1000Research, November 2021, Faculty of 1000, Ltd.

    Prof Sergey E Dmitriev

  11. Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation

    Article • November 2021, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  12. Systematic identification of yeast mutants with increased rates of cell death reveals rapid stochastic necrosis associated with cell division

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  13. A standard knockout procedure alters expression of adjacent loci at the translational level

    Article • Nucleic Acids Research, October 2021, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  14. A standard knockout procedure alters expression of adjacent loci at the translational level

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  15. Abstract P-22: Enhanced Crosslinking and Immunoprecipitation (Eclip) Data Reveal Interactions of RNA Binding Proteins with the Human Ribosome

    Article • International Journal of Biomedicine, June 2021, International Medical Research and Development Corporation

    Prof Sergey E Dmitriev

  16. Assessing Ribosome Distribution Along Transcripts with Polarity Scores and Regression Slope Estimates

    Article • January 2021, Springer Science + Business Media

    Prof Sergey E Dmitriev

  17. Patterns of aging biomarkers, mortality, and damaging mutations illuminate the beginning of aging and causes of early-life mortality

    Article • Yearbook of Paediatric Endocrinology, October 2020, Bioscientifica

    Prof Sergey E Dmitriev

  18. Multifaceted deregulation of gene expression and protein synthesis with age

    Article • Proceedings of the National Academy of Sciences, June 2020, Proceedings of the National Academy of Sciences

    Prof Sergey E Dmitriev

  19. CTELS: A Cell-Free System for the Analysis of Translation Termination Rate

    Article • Biomolecules, June 2020, MDPI AG

    Prof Sergey E Dmitriev

  20. Functional Cyclization of Eukaryotic mRNAs

    Article • International Journal of Molecular Sciences, February 2020, MDPI AG

    Prof Sergey E Dmitriev

  21. Multi-faceted deregulation of gene expression and protein synthesis with age

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  22. Patterns of Aging Biomarkers, Mortality, and Damaging Mutations Illuminate the Beginning of Aging and Causes of Early-Life Mortality

    Article • Cell Reports, December 2019, Elsevier

    Prof Sergey E Dmitriev

  23. Abstract P-17: Structural and Functional Insights into Eukaryotic Translation Reinitiation and Ribosome Recycling Orchestrated by eIF2D and MCT-1/DENR

    Article • International Journal of Biomedicine, June 2019, International Medical Research and Development Corporation

    Prof Sergey E Dmitriev

  24. A novel uORF-based regulatory mechanism controls translation of the human MDM2 and eIF2D mRNAs during stress

    Article • Biochimie, February 2019, Elsevier

    Prof Sergey E Dmitriev

  25. Protein synthesis and quality control in aging

    Article • Aging, December 2018, Impact Journals, LLC

    Prof Sergey E Dmitriev

  26. Reversibility of irreversible aging

    Article • Ageing Research Reviews, December 2018, Elsevier

    Prof Sergey E Dmitriev

  27. Crystal Structure of the Human Ribosome in Complex with DENR-MCT-1

    Article • Cell Reports, July 2017, Elsevier

    Prof Sergey E Dmitriev

  28. Crystal Structure of the C-terminal Domain of Human eIF2D and its Implications on Eukaryotic Translation Initiation

    Article • Journal of Molecular Biology, July 2017, Elsevier

    Prof Sergey E Dmitriev

  29. Synergistic suppression of t(8;21)-positive leukemia cell growth by combining oridonin and MAPK1/ERK2 inhibitors

    Article • Oncotarget, June 2017, Impact Journals, LLC

    Prof Sergey E Dmitriev

  30. Insights into the mechanisms of eukaryotic translation gained with ribosome profiling

    Article • Nucleic Acids Research, December 2016, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  31. Late Diagnosis of POMC Deficiency and in vitro evidence of residual translation from allele with c.-11C>A mutation

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2016, Endocrine Society

    Dr Anatoly Tiulpakov, Dr. Petr M Rubtsov, Prof Sergey E Dmitriev, Ms. Aleksandra S Anisimova

  32. Four translation initiation pathways employed by the leaderless mRNA in eukaryotes

    Article • Scientific Reports, November 2016, Nature

    Prof Sergey E Dmitriev

  33. A researcher’s guide to the galaxy of IRESs

    Article • Cellular and Molecular Life Sciences, November 2016, Springer Science + Business Media

    Prof Sergey E Dmitriev

  34. Early B-cell factor 1 (EBF1) is critical for transcriptional control of SLAMF1 gene in human B cells

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, October 2016, Elsevier

    Prof Sergey E Dmitriev

  35. Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome

    Article • Scientific Reports, June 2016, Nature

    Prof Sergey E Dmitriev

  36. Pros and cons of pDNA and mRNA transfection to study mRNA translation in mammalian cells

    Article • Gene, March 2016, Elsevier

    Prof Sergey E Dmitriev

  37. Does HIV-1 mRNA 5'-untranslated region bear an internal ribosome entry site?

    Article • Biochimie, February 2016, Elsevier

    Prof Sergey E Dmitriev

  38. Sliding of a 43S ribosomal complex from the recognized AUG codon triggered by a delay in eIF2-bound GTP hydrolysis

    Article • Nucleic Acids Research, December 2015, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  39. RNA-seq analysis of an apical meristem time series reveals a critical point in Arabidopsis thaliana flower initiation

    Article • BMC Genomics, June 2015, Springer Science + Business Media

    Prof Sergey E Dmitriev

  40. Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

    Article • eLife, January 2015, eLife

    Dr Dmitry Andreev, Prof Sergey E Dmitriev

  41. Upstream open reading frames regulate translation of the long isoform of SLAMF1 mRNA that encodes costimulatory receptor CD150

    Article • Biochemistry (Moscow), December 2014, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  42. Identification of a Mg2+-sensitive ORF in the 5'-leader of TRPM7 magnesium channel mRNA

    Article • Nucleic Acids Research, October 2014, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  43. Silencing AML1-ETO gene expression leads to simultaneous activation of both pro-apoptotic and proliferation signaling

    Article • Leukemia, April 2014, Nature

    Prof Sergey E Dmitriev, Dr. Petr M Rubtsov

  44. Transcriptome-wide studies uncover the diversity of modes of mRNA recruitment to eukaryotic ribosomes

    Article • Critical Reviews in Biochemistry and Molecular Biology, February 2014, Taylor & Francis

    Prof Sergey E Dmitriev

  45. Human-specific endogenous retroviral insert serves as an enhancer for the schizophrenia-linked gene PRODH

    Article • Proceedings of the National Academy of Sciences, November 2013, Proceedings of the National Academy of Sciences

    Prof Sergey E Dmitriev

  46. Cap-independent translation initiation of Apaf-1 mRNA based on a scanning mechanism is determined by some features of the secondary structure of its 5′ untranslated region

    Article • Biochemistry (Moscow), February 2013, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  47. A novel mechanism of eukaryotic translation initiation that is neither m7G-cap-, nor IRES-dependent

    Article • Nucleic Acids Research, December 2012, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  48. In vitro activity of human translation initiation factor eIF4B is not affected by phosphomimetic amino acid substitutions S422D and S422E

    Article • Biochimie, December 2012, Elsevier

    Prof Sergey E Dmitriev

  49. Sense transcripts originated from an internal part of the human retrotransposon LINE-1 5′ UTR

    Article • Gene, December 2012, Elsevier

    Prof Sergey E Dmitriev

  50. The 5′ untranslated region of Apaf-1 mRNA directs translation under apoptosis conditions via a 5′ end-dependent scanning mechanism

    Article • FEBS Letters, October 2012, Wiley

    Prof Sergey E Dmitriev

  51. Glycyl-tRNA synthetase specifically binds to the poliovirus IRES to activate translation initiation

    Article • Nucleic Acids Research, February 2012, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  52. Archaeal Translation Initiation Factor aIF2 Can Substitute for Eukaryotic eIF2 in Ribosomal Scanning during Mammalian 48S Complex Formation

    Article • Journal of Molecular Biology, October 2011, Elsevier

    Dr Dmitry Andreev, Prof Sergey E Dmitriev

  53. Design of Targeted B Cell Killing Agents

    Article • PLoS ONE, June 2011, PLOS

    Prof Sergey E Dmitriev

  54. Unidirectional constant rate motion of the ribosomal scanning particle during eukaryotic translation initiation

    Article • Nucleic Acids Research, March 2011, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  55. Cap- and IRES-independent scanning mechanism of translation initiation as an alternative to the concept of cellular IRESs

    Article • Molecules and Cells, October 2010, Springer Science + Business Media

    Prof Sergey E Dmitriev

  56. GTP-independent tRNA Delivery to the Ribosomal P-site by a Novel Eukaryotic Translation Factor

    Article • Journal of Biological Chemistry, June 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Sergey E Dmitriev

  57. Differential contribution of the m7G-cap to the 5′ end-dependent translation initiation of mammalian mRNAs

    Article • Nucleic Acids Research, August 2009, Oxford University Press (OUP)

    Prof Sergey E Dmitriev

  58. Efficient cap-dependent translation of mammalian mRNAs with long and highly structured 5′-untranslated regions in vitro and in vivo

    Article • Molecular Biology, February 2009, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  59. Eukaryotic translation initiation machinery can operate in a bacterial-like mode without eIF2

    Article • Nature Structural & Molecular Biology, July 2008, Springer Science + Business Media

    Dr Dmitry Andreev, Prof Sergey E Dmitriev

  60. The bacterial toxin RelE induces specific mRNA cleavage in the A site of the eukaryote ribosome

    Article • RNA, December 2007, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  61. Differential factor requirement to assemble translation initiation complexes at the alternative start codons of foot-and-mouth disease virus RNA

    Article • RNA, June 2007, Cold Spring Harbor Laboratory Press

    Prof Sergey E Dmitriev

  62. Key role of the internal 5′-UTR segment in the transcription activity of the human L1 retrotransposon

    Article • Molecular Biology, June 2007, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  63. Efficient Translation Initiation Directed by the 900-Nucleotide-Long and GC-Rich 5′ Untranslated Region of the Human Retrotransposon LINE-1 mRNA Is Strictly Cap Dependent Rather than Internal Ribosome Entry Site Mediated

    Article • Molecular and Cellular Biology, April 2007, ASM Journals

    Prof Sergey E Dmitriev

  64. Similar features in the mechanisms of mRNA translation initiation in eukaryotic and prokaryotic systems

    Article • Molecular Biology, July 2006, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  65. A Leaderless mRNA Can Bind to Mammalian 80S Ribosomes and Direct Polypeptide Synthesis in the Absence of Translation Initiation Factors

    Article • Molecular and Cellular Biology, April 2006, ASM Journals

    Prof Sergey E Dmitriev

  66. Adequate system for studying translation initiation on the human retrotransposon L1 mRNA in vitro

    Article • Molecular Biology, January 2006, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  67. Analysis of point mutations of the BRCA1 gene by hybridization with hydrogel microarrays

    Article • Molecular Biology, January 2006, Pleiades Publishing Ltd

    Prof Sergey E Dmitriev

  68. A Cross-Kingdom Internal Ribosome Entry Site Reveals a Simplified Mode of Internal Ribosome Entry

    Article • Molecular and Cellular Biology, September 2005, ASM Journals

    Professor Graham J. Belsham, Prof Sergey E Dmitriev

  69. Mutual Effects of Translation Initiation Factors in Binding to the IRES of the Encephalomyocarditis Virus RNA

    Article • Molecular Biology, March 2004, Springer Science + Business Media

    Prof Sergey E Dmitriev

  70. Assembly of 48S Translation Initiation Complexesfrom Purified Components with mRNAs That Have Some Base Pairingwithin Their 5′ UntranslatedRegions

    Article • Molecular and Cellular Biology, December 2003, ASM Journals

    Prof Sergey E Dmitriev

  71. Distinctive Properties of the 5′-Untranslated Region of Human Hsp70 mRNA

    Article • Journal of Biological Chemistry, April 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof Sergey E Dmitriev

  72. Article • Molecular Biology, January 2003, Springer Science + Business Media

    Prof Sergey E Dmitriev

  73. Conversion of 48S translation preinitiation complexes into 80S initiation complexes as revealed by toeprinting

    Article • FEBS Letters, December 2002, Wiley

    Prof Sergey E Dmitriev