All Stories

  1. Longitudinal model for a dose-finding study for a rare disease treatment

    Article • Statistical Papers, March 2023, Springer Science + Business Media

    Dr Sergei Leonov

  2. Statistical Approaches in the Development of Digital Therapeutics

    Article • September 2022, Taylor & Francis

    Dr Sergei Leonov

  3. Simulation Practices For Adaptive Trial Designs In Drug And Device Development

    Article • Statistics in Biopharmaceutical Research, January 2019, Taylor & Francis

    Inna Perevozskaya, Dr Sergei Leonov

  4. Correlated endpoints: simulation, modeling, and extreme correlations

    Article • Statistical Papers, October 2017, Springer Science + Business Media

    Dr Sergei Leonov

  5. Methods and software tools for design evaluation in population pharmacokinetics-pharmacodynamics studies

    Article • British Journal of Clinical Pharmacology, December 2014, Wiley

    Dr Sergei Leonov

  6. Optimal Design for Nonlinear Response Models

    Article • July 2013, Taylor & Francis

    Dr Sergei Leonov

  7. Approximation of the Fisher Information Matrix for Nonlinear Mixed Effects Models in Population PK/PD Studies

    Article • January 2013, Springer Science + Business Media

    Dr Sergei Leonov

  8. Optimal design for population pk/pd models

    Article • Tatra Mountains Mathematical Publications, November 2012, De Gruyter

    Dr Sergei Leonov

  9. PkStaMp Library for Constructing Optimal Population Designs for PK/PD Studies

    Article • Communications in Statistics - Simulation and Computation, January 2012, Taylor & Francis

    Dr Sergei Leonov

  10. Pharmacokinetic Studies Described by Stochastic Differential Equations: Optimal Design for Systems with Positive Trajectories

    Article • January 2010, Springer Science + Business Media

    Dr Sergei Leonov

  11. An Adaptive Optimal Design for the E max Model and Its Application in Clinical Trials

    Article • Journal of Biopharmaceutical Statistics, February 2009, Taylor & Francis

    Dr Sergei Leonov

  12. Discussion of the “White Paper of the PhRMA PISC Working Group on Adaptive Dose-Ranging Designs”

    Article • Journal of Biopharmaceutical Statistics, November 2007, Taylor & Francis

    Dr Sergei Leonov

  13. Population Pharmacokinetic Measures, Their Estimation and Selection of Sampling Times

    Article • Journal of Biopharmaceutical Statistics, August 2007, Taylor & Francis

    Dr Sergei Leonov

  14. Practical usage of O'Brien's OLS and GLS statistics in clinical trials

    Article • Pharmaceutical Statistics, March 2007, Wiley

    Dr Sergei Leonov

  15. Sample size calculation for the Power Model for dose proportionality studies

    Article • Pharmaceutical Statistics, January 2007, Wiley

    Dr Sergei Leonov

  16. Methods of Selecting Informative Variables

    Article • Biometrical Journal, February 2006, Wiley

    Dr Sergei Leonov, Mario Berberan-Santos

  17. Response-Driven Designs in Drug Development

    Article • October 2005, Wiley

    Dr Sergei Leonov

  18. OPTIMAL POPULATION DESIGNS FOR PK MODELS WITH SERIAL SAMPLING

    Article • Journal of Biopharmaceutical Statistics, December 2004, Taylor & Francis

    Dr Sergei Leonov

  19. Optimal Designs for Regression Models with Forced Measurements at Baseline

    Article • January 2004, Springer Science + Business Media

    Dr Sergei Leonov

  20. Parameter Estimation for Models with Unknown Parameters in Variance

    Article • Communication in Statistics- Theory and Methods, January 2004, Taylor & Francis

    Dr Sergei Leonov

  21. Component-wise dimension reduction

    Article • Journal of Statistical Planning and Inference, June 2003, Elsevier

    Dr Sergei Leonov

  22. Design of experiments with unknown parameters in variance

    Article • Applied Stochastic Models in Business and Industry, January 2002, Wiley

    Dr Sergei Leonov

  23. Nonparametric methods for clutter removal

    Article • IEEE Transactions on Aerospace and Electronic Systems, July 2001, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Sergei Leonov

  24. Extracting Information from the Variance Function: Optimal Design

    Article • January 2001, Springer Science + Business Media

    Dr Sergei Leonov

  25. Remarks on extremal problems in nonparametric curve estimation

    Article • Statistics & Probability Letters, June 1999, Elsevier

    Dr Sergei Leonov

  26. BAHADUR-TYPE RISKS AND OPTIMAL DESIGNS IN REGRESSION PROBLEMS

    Article • Statistics & Risk Modeling, January 1998, De Gruyter

    Dr Sergei Leonov

  27. Action functional for diffusions in discontinuous media

    Article • Probability Theory and Related Fields, September 1993, Springer Science + Business Media

    Dr Sergei Leonov

  28. Action Functional for a Diffusion Process with Discontinuous Drift

    Article • Theory of Probability and Its Applications, January 1993, Society for Industrial & Applied Mathematics (SIAM)

    Dr Sergei Leonov

  29. Optimal Design of Pharmacokinetic Studies Described by Stochastic Differential Equations

    Article • Springer Science + Business Media

    Prof Vladimir Anisimov, Dr Sergei Leonov