All Stories

  1. The Role of MicroRNA in Pathogenesis and as Markers of HCV Chronic Infection

    Article • Current Drug Targets, April 2017, Bentham Science Publishers

    Dr Seong-Wook Lee

  2. The Roles of Carcinoembryonic Antigen in Liver Metastasis and Therapeutic Approaches

    Article • Gastroenterology Research and Practice, January 2017, Hindawi Publishing Corporation

    Dr Seong-Wook Lee

  3. Recombinant adenovirus infection suppresses hTERT expression through virus-associated RNA-mediated induction of type 1 interferon

    Article • Biochemical and Biophysical Research Communications, March 2015, Elsevier

    Dr Seong-Wook Lee

  4. Selective expression of transgene using hypoxia-inducible trans-splicing group I intron ribozyme

    Article • Journal of Biotechnology, December 2014, Elsevier

    Dr Seong-Wook Lee

  5. Conditional and Target-Specific Transgene Induction through RNA Replacement Using an Allosteric Trans-Splicing Ribozyme

    Article • ACS Chemical Biology, September 2014, American Chemical Society (ACS)

    Dr Seong-Wook Lee

  6. In vitro selection of RNA aptamers that selectively bind danofloxacin

    Article • Biochemical and Biophysical Research Communications, June 2014, Elsevier

    Dr Seong-Wook Lee

  7. The role of microRNAs in Hepatitis C Virus replication and related liver diseases

    Article • The Journal of Microbiology, May 2014, Springer Science + Business Media

    Dr Seong-Wook Lee

  8. Use of Tumor-Targeting Trans-Splicing Ribozyme for Cancer Treatment

    Article • October 2013, Springer Science + Business Media

    Dr Seong-Wook Lee

  9. In vitro selection of RNA aptamer specific to Staphylococcus aureus

    Article • Annals of Microbiology, October 2013, Springer Science + Business Media

    Dr Seong-Wook Lee

  10. Induced Degradation of Tat by Nucleocapsid (NC) via the Proteasome Pathway and Its Effect on HIV Transcription

    Article • Viruses, April 2013, MDPI AG

    Dr Seong-Wook Lee, Professor Heejoon Myung

  11. Inhibition of Hepatitis C Virus (HCV) Replication by Specific RNA Aptamers against HCV NS5B RNA Replicase

    Article • Journal of Virology, April 2013, ASM Journals

    Dr Seong-Wook Lee

  12. Carbon Nanotube-Patterned Surface-Based Recognition of Carcinoembryonic Antigens in Tumor Cells for Cancer Diagnosis

    Article • The Journal of Physical Chemistry Letters, March 2013, American Chemical Society (ACS)

    Dr Seong-Wook Lee, Professor Kilho Eom

  13. An RNA Aptamer That Binds Carcinoembryonic Antigen Inhibits Hepatic Metastasis of Colon Cancer Cells in Mice

    Article • Gastroenterology, July 2012, Elsevier

    Dr Seong-Wook Lee

  14. Rapid Detection of Food Pathogens Using RNA Aptamers-Immobilized Slide

    Article • Journal of Nanoscience and Nanotechnology, July 2012, American Scientific Publishers

    Dr Seong-Wook Lee

  15. Cancer-Specific Induction of Adenoviral E1A Expression by Group I Intron-Based Trans-Splicing Ribozyme

    Article • Journal of Microbiology and Biotechnology, March 2012, Korean Society for Microbiology and Biotechnology

    Dr Seong-Wook Lee

  16. Selective regression of cancer cells expressing a splicing variant of AIMP2 through targeted RNA replacement by trans-splicing ribozyme

    Article • Journal of Biotechnology, March 2012, Elsevier

    Dr Seong-Wook Lee

  17. Hepatitis C Virus Replication-Specific Inhibition of MicroRNA Activity with Self-Cleavable Allosteric Ribozyme

    Article • Nucleic Acid Therapeutics, January 2012, Mary Ann Liebert Inc

    Dr Seong-Wook Lee, Professor Heejoon Myung

  18. Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein

    Article • Biochemical and Biophysical Research Communications, January 2012, Elsevier

    Dr Seong-Wook Lee

  19. Introducing the Korean Oligonucleotide Therapeutics Society

    Article • Nucleic Acid Therapeutics, June 2011, Mary Ann Liebert Inc

    Dr Seong-Wook Lee

  20. Intracellular efficacy of tumor‐targeting group I intron‐based trans‐splicing ribozyme

    Article • The Journal of Gene Medicine, February 2011, Wiley

    Dr Seong-Wook Lee

  21. Identification of RNA Aptamer Specific to Mutant KRAS Protein

    Article • Oligonucleotides, June 2010, Mary Ann Liebert Inc

    Dr Seong-Wook Lee

  22. Comparative analysis of intracellular inhibition of hepatitis C virus replication by small interfering RNAs

    Article • Biotechnology Letters, May 2010, Springer Science + Business Media

    Dr Seong-Wook Lee

  23. In Vivo Reprogramming of Human Telomerase Reverse Transcriptase (hTERT) by Trans-Splicing Ribozyme to Target Tumor Cells

    Article • January 2010, Springer Science + Business Media

    Dr Seong-Wook Lee

  24. Selection of RNA aptamers specific to active prostate-specific antigen

    Article • Biotechnology Letters, November 2009, Springer Science + Business Media

    Dr Seong-Wook Lee

  25. Sequence and Structural Features of RNA Aptamer Against Myasthenic Autoantibodies

    Article • Oligonucleotides, September 2009, Mary Ann Liebert Inc

    Dr Seong-Wook Lee

  26. RNA aptamer-based sensitive detection of SARS coronavirus nucleocapsid protein

    Article • The Analyst, January 2009, Royal Society of Chemistry

    Dr Seong-Wook Lee

  27. hnRNP L is required for the translation mediated by HCV IRES

    Article • Biochemical and Biophysical Research Communications, January 2009, Elsevier

    Dr Seong-Wook Lee

  28. In Vivo Reprogramming of hTERT by Trans-splicing Ribozyme to Target Tumor Cells

    Article • Molecular Therapy, January 2008, Elsevier

    Dr Seong-Wook Lee

  29. Gene expression responses in vivo by human telomerase reverse transcriptase (hTERT)-targeting trans-splicing ribozyme

    Article • Experimental & Molecular Medicine, December 2007, Springer Science + Business Media

    Dr Seong-Wook Lee

  30. Molecular imaging of endogenous mRNA expression in a mouse tumor model by adenovirus harboring trans‐splicing ribozyme

    Article • FEBS Letters, October 2007, Wiley

    Dr Seong-Wook Lee

  31. Targeted retardation of hepatocarcinoma cells by specific replacement of alpha-fetoprotein RNA

    Article • Journal of Biotechnology, May 2007, Elsevier

    Dr Seong-Wook Lee

  32. Selective Regression of Cells Expressing Mouse Cytoskeleton-Associated Protein 2 Transcript by Trans -Splicing Ribozyme

    Article • Oligonucleotides, March 2007, Mary Ann Liebert Inc

    Dr Seong-Wook Lee

  33. Ribozyme-mediated selective killing of cancer cells expressing carcinoembryonic antigen RNA by targeted trans-splicing

    Article • Biochemical and Biophysical Research Communications, October 2006, Elsevier

    Dr Seong-Wook Lee

  34. Cancer‐selective induction of cytotoxicity by tissue‐specific expression of targeted trans‐splicing ribozyme

    Article • FEBS Letters, August 2006, Wiley

    Dr Seong-Wook Lee

  35. Specific Regression of Human Cancer Cells by Ribozyme-Mediated Targeted Replacement of Tumor-Specific Transcript

    Article • Molecular Therapy, November 2005, Elsevier

    Dr Seong-Wook Lee

  36. Tumor-specific gene delivery using RNA-targeting Tetrahymena group I intron

    Article • Biotechnology Letters, April 2005, Springer Science + Business Media

    Dr Seong-Wook Lee

  37. Isolation of specific and high-affinity RNA aptamers against NS3 helicase domain of hepatitis C virus

    Article • RNA, July 2004, Cold Spring Harbor Laboratory Press

    Dr Seong-Wook Lee

  38. Computational analysis of hydrogen bonds in protein–RNA complexes for interaction patterns

    Article • FEBS Letters, August 2003, Wiley

    Dr Seong-Wook Lee

  39. Prevention of passively transferred experimental autoimmune myasthenia gravis by an in vitro selected RNA aptamer

    Article • FEBS Letters, July 2003, Wiley

    Dr Seong-Wook Lee

  40. Ribozyme-mediated selective induction of new gene activity in hepatitis C virus internal ribosome entry site-expressing cells by targeted trans-splicing

    Article • Molecular Therapy, March 2003, Elsevier

    Dr Seong-Wook Lee

  41. In vitro selection of specific RNA inhibitors of NFATc

    Article • Biochemical and Biophysical Research Communications, November 2002, Elsevier

    Dr Seong-Wook Lee

  42. Improvement of RNA Aptamer Activity against Myasthenic Autoantibodies by Extended Sequence Selection

    Article • Biochemical and Biophysical Research Communications, January 2002, Elsevier

    Dr Seong-Wook Lee

  43. Trans-Splicing Ribozymes as Potential HIV Gene Inhibitors

    Article • January 1998, Springer Science + Business Media

    Dr Seong-Wook Lee

  44. Isolation of a nuclease-resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies

    Article • Nature Biotechnology, January 1997, Springer Science + Business Media

    Dr Seong-Wook Lee

  45. Tagging ribozyme reaction sites to follow trans–splicing in mammalian cells

    Article • Nature Medicine, June 1996, Springer Science + Business Media

    Dr Seong-Wook Lee

  46. Inhibition of HIV-1 with intracellular immunization with RNA decoys

    Article • Advanced Drug Delivery Reviews, December 1995, Elsevier

    Dr Seong-Wook Lee

  47. Trans-Splicing Reactions by Ribozymes

    Article • Springer Science + Business Media

    Dr Seong-Wook Lee