Samiha El-Sebaey

All Stories

1. 
   Novel thioxoimidazolidinone derivatives as dual EGFR and CDK2 inhibitors: Design, synthesis, anticancer evaluation with in silico study

   Article • Journal of Molecular Structure, November 2023, Elsevier

   Samiha El-Sebaey

2. 
   Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling

   Article • Journal of Enzyme Inhibition and Medicinal Chemistry, July 2023, Taylor & Francis

   Samiha El-Sebaey

3. 
   Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors

   Article • Journal of Enzyme Inhibition and Medicinal Chemistry, April 2023, Taylor & Francis

   Samiha El-Sebaey

4. 
   Synthesis and Exploration of New Imidazo[4,5‐c]Pyrazoles as Potent α‐Amylase Inhibitors

   Article • ChemistrySelect, April 2023, Wiley

   Samiha El-Sebaey

5. 
   Synthesis of pyrido-annelated [1,2,4,5]tetrazines, [1,2,4]triazepine, and [1,2,4,5]tetrazepines for anticancer, DFT, and molecular docking studies

   Article • Scientific Reports, April 2023, Springer Science + Business Media

   Samiha El-Sebaey

6. 
   Design and synthesis of new series of chiral pyrimidine and purine analogs as COX-2 inhibitors: Anticancer screening, molecular modeling, and in silico studies

   Article • Journal of Molecular Structure, April 2023, Elsevier

   Samiha El-Sebaey

7. 
   Design, synthesis, docking, and anticancer evaluations of new thiazolo[3,2-a] pyrimidines as topoisomerase II inhibitors

   Article • Journal of Enzyme Inhibition and Medicinal Chemistry, February 2023, Taylor & Francis

   Samiha El-Sebaey

8. 
   Design, synthesis and Molecular modeling study of certain EGFR inhibitors with a quinazolinone scaffold as anti-hepatocellular carcinoma and Radio-sensitizers

   Article • Bioorganic Chemistry, February 2023, Elsevier

   Samiha El-Sebaey

9. 
   Design, synthesis and molecular modeling study of certain quinazolinone derivatives targeting poly (ADP-ribose) polymerase 1 (PARP-1) enzyme as anti-breast cancer and radio-sensitizers

   Article • Journal of Molecular Structure, February 2023, Elsevier

   Samiha El-Sebaey

10. 
    New [1,2,4]triazolo[4,3-c]quinazolines as intercalative Topo II inhibitors: Design, synthesis, biological evaluation, and in silico studies

    Article • PLoS ONE, January 2023, PLOS

    Samiha El-Sebaey, Wagdy Eldehna

11. 
    New Pyrimidine-5-Carbonitriles as COX-2 Inhibitors: Design, Synthesis, Anticancer Screening, Molecular Docking, and In Silico ADME Profile Studies

    Article • Molecules, November 2022, MDPI AG

    Samiha El-Sebaey

12. 
    Potential antiviral and anticancer effect of imidazoles and bridgehead imidazoles generated by HPV-Induced cervical carcinomas via reactivating the P53/ pRb pathway and inhibition of CA IX

    Article • Journal of Molecular Structure, April 2021, Elsevier

    Samiha El-Sebaey

13. 
    New benzothieno[2,3-c]pyridines as non-steroidal CYP17 inhibitors: design, synthesis, anticancer screening, apoptosis induction, and in silico ADME profile studies

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2021, Taylor & Francis

    Samiha El-Sebaey

14. 
    Recent Advances in 1,2,4‐Triazole Scaffolds as Antiviral Agents

    Article • ChemistrySelect, October 2020, Wiley

    Samiha El-Sebaey

15. 
    Derivatives and Fused Heterocyclic Compounds Derived from Thieno[2,3‐ b]pyridine: Recent Perspective

    Article • July 2020, Sciencedomain International

    Samiha El-Sebaey, Dr. Nadia Ali Ahmed Elkanzi

16. 
    Synthesis and antitumor evaluation of some new derivatives and fused heterocyclic compounds derived from thieno[2,3‐ b ]pyridine: Part 2

    Article • Journal of Heterocyclic Chemistry, November 2019, Wiley

    Samiha El-Sebaey

17. 
    Synthesis and antitumor evaluation of some new derivatives and fused heterocyclic compounds derived from thieno[2,3‐b]pyridine

    Article • Journal of Heterocyclic Chemistry, September 2019, Wiley

    Samiha El-Sebaey

18. 
    Utility of thieno[2,3-b] pyridine derivatives in the synthesis of some condensed heterocyclic compounds with expected biological activity

    Article • Universal Organic Chemistry, January 2013, Herbert Publications PVT LTD

    Samiha El-Sebaey