All Stories

  1. Design, Synthesis and In Vitro Anti-Cancer Evaluation of Novel Derivatives of 2-(2-Methyl-1,5-diaryl-1H-pyrrol-3-yl)-2-oxo-N-(pyridin-3- yl)acetamide
  2. Stepwise development of biomimetic chimeric peptides for gene delivery
  3. Cholesterol-rich lipid-mediated nanoparticles boost of transfection efficiency, utilized for gene editing by CRISPR-Cas9
  4. Effects of microbial volatile organic compounds on Ganoderma lucidum growth and ganoderic acids production in Co-v-cultures (volatile co-cultures)
  5. Bioluminescence-based detection of astrocytes apoptosis and ATP depletion induced by biologically relevant level aflatoxin B1
  6. Preparation of liposomal doxorubicin-graphene nanosheet and evaluation of its in vitro anti-cancer effects
  7. Reversible permeabilization of the mitochondrial membrane promotes human cardiomyocyte differentiation from embryonic stem cells
  8. In vivo tumor gene delivery using novel peptideticles: pH-responsive and ligand targeted core-shell nanoassembly
  9. Investigation of the effects of carbon-based nanomaterials on A53T alpha-synuclein aggregation using a whole-cell recombinant biosensor
  10. The effect of a β-Synuclein Derived Peptide on Aggregates of α -Synuclein Mutants
  11. Structural and functional study of a simple, rapid, and label-free DNAzyme-based DNA biosensor for optimization activity
  12. The Global Ethics Corner: foundations, beliefs, and the teaching of biomedical and scientific ethics around the world
  13. An alternative approach in regulation of expression of a transgene by endogenous miR-145 in carcinoma and normal breast cell lines
  14. Enhancement of cell internalization and photostability of red and green emitter quantum dots upon entrapment in novel cationic nanoliposomes
  15. Enhanced and selective permeability of gold nanoparticles functionalized with cell penetrating peptide derived from maurocalcine animal toxin
  16. Hydrophobin-1 promotes thermostability of firefly luciferase
  17. Label free colorimetric and fluorimetric direct detection of methylated DNA based on silver nanoclusters for cancer early diagnosis
  18. Oscillation of apoptosome formation through assembly of truncated Apaf-1
  19. The Effect of Surface Charge Saturation on Heat-induced Aggregation of Firefly Luciferase
  20. Ursolic acid ameliorates aging-metabolic phenotype through promoting of skeletal muscle rejuvenation
  21. Kit ligand decreases the incidence of apoptosis in cultured vitrified whole mouse ovaries
  22. Hyperactive Arg39Lys mutated mnemiopsin: implication of positively charged residue in chromophore binding cavity
  23. Luciferin-Regenerating Enzyme Mediates Firefly Luciferase Activation Through Direct Effects of D-Cysteine on Luciferase Structure and Activity
  24. Impact of trifluoroethanol-induced structural changes on luciferase cleavage sites
  25. Differentiation of human skin-derived precursor cells into functional islet-like insulin-producing cell clusters
  26. Hydrogen peroxide sensitive hemoglobin-capped gold nanoclusters as a fluorescence enhancing sensor for the label-free detection of glucose
  27. Investigation of oxidative phosphorylation in continuous cultures. A non-equilibrium thermodynamic approach to energy transduction for Escherichia coli in aerobic condition
  28. Implication of Disulfide Bridge Induced Thermal Reversibility, Structural and Functional Stability for Luciferase
  29. Directed Improvement of Luciferin Regenerating Enzyme Binding Properties: Implication of Some Conserved Residues in Luciferin-Binding Domain
  30. Split-luciferase complementary assay: applications, recent developments, and future perspectives
  31. Effects of 940 MHz EMF on bioluminescence and oxidative response of stable luciferase producing HEK cells
  32. Quenching effect of deferoxamine on free radical-mediated photon production in luminol and ortho-phenanthroline-dependent chemiluminescence
  33. Effect of GTP and GDP nucleotides on vinblastine binding affinity to tubulin: a DFT study
  34. Conjugated linoleic acid production from various substrates by probiotic Lactobacillus plantarum
  35. Magnetic Nanoparticles Supported Ionic Liquids Improve Firefly Luciferase Properties
  36. Evaluation of apoptosis in long-term culture of vitrified mouse whole ovaries
  37. Crystal structure of native and a mutant of Lampyris turkestanicus luciferase implicate in bioluminescence color shift
  38. Crystal structure of a green-emitter native of Lampyris turkestanicus luciferase
  39. Structural and functional effects of circular permutation on firefly luciferase: In vitro assay of caspase 3/7
  40. Nanofiber-based polyethersulfone scaffold and efficient differentiation of human induced pluripotent stem cells into osteoblastic lineage
  41. Characterization of Zwitterionic Phosphatidylcholine-Based Bilayer Vesicles as Efficient Self-Assembled Virus-Like Gene Carriers
  42. Biased Homozygous Haplotypes Across the Human Caveolin 1 Upstream Purine Complex in Parkinson’s Disease
  43. Effects of 940 MHz EMF on luciferase solution: Structure, function, and dielectric studies
  44. Lipid composition of cationic nanoliposomes implicate on transfection efficiency
  45. Stabilisation of Recombinant Aequorin by Polyols: Activity, Thermostability and Limited Proteolysis
  46. Site-directed mutagenesis of photoprotein mnemiopsin: implication of some conserved residues in bioluminescence properties
  47. A novel luminescent biosensor for rapid monitoring of IP3 by split-luciferase complementary assay
  48. Step-wise addition of disulfide bridge in firefly luciferase controls color shift through a flexible loop: a thermodynamic perspective
  49. Static magnetic field of 6 mT induces apoptosis and alters cell cycle in p53 mutant Jurkat cells
  50. Gamma radiation alters cell cycle and induces apoptosis in p53 mutant E6.1 Jurkat cells
  51. Implication of Arg213 and Arg337 on the kinetic and structural stability of firefly luciferase
  52. Aberrant expression of Activating Transcription Factor 6 (ATF6) in major psychiatric disorders
  53. Delicate balance of electrostatic interactions and disulfide bridges in thermostability of firefly luciferase
  54. Water-miscible ionic liquids as novel effectors for the firefly luciferase reaction
  55. How benzene and its metabolites affect human marrow derived mesenchymal stem cells
  56. Design and development of a whole-cell luminescent biosensor for detection of early-stage of apoptosis
  57. Implication of an unfavorable residue (Thr346) in intrinsic flexibility of firefly luciferase
  58. Improvement of Thermostability and Activity of Firefly Luciferase Through [TMG][Ac] Ionic Liquid Mediator
  59. Evaluation of Immunogenicity of Purified Cell Wall-Associated 34 kDa Antigen ofMycobacterium aviumsubsp.paratuberculosisInfection
  60. Controversial effect of two methylguanidine-based ionic liquids on firefly luciferase
  61. Design, engineering and preparation of a multi-domain fusion vector for gene delivery
  62. Stability studies of chitosan-DNA-FAP-B nanoparticles for gene delivery to lung epithelial cells
  63. Relationship between stability and flexibility in the most flexible region of Photinus pyralis luciferase
  64. Renilla luciferase-labeled Annexin V: a new probe for detection of apoptotic cells
  65. Red blood cell ATP/ADP & nitric oxide: The best vasodilators in diabetic patients
  66. Prevention of thermal aggregation of an allosteric protein by small molecules: Some mechanistic insights
  67. Cloning, Sequencing, Expression and Structural Investigation of Mnemiopsin from Mnemiopsis leidyi: An Attempt Toward Understanding Ca2+-Regulated Photoproteins
  68. Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes
  69. Deletion of extra C-terminal segment and its effect on the function and structure of artemin
  70. Design of disulfide bridge as an alternative mechanism for color shift in firefly luciferase
  71. Investigation of disulfide bridge and polar amino acid mutations effect on luciferase structure and function
  72. Site directed mutagenesis of SOD1 (Gly72Ser) and analysis of mutant proteins oligomerization
  73. Molecular cloning of amino-terminal region of human type 2 inositol 1,4,5-trisphosphate receptor
  74. Functional study of mnemiopsin photoprotein using site directed mutagenesis
  75. The effect of Zn2+ on exposure of hydrophobic patches of carbonic anhydrase
  76. Analysis of human SOD1 oligomerization in native and mutant forms (D102N and L127S)
  77. Influence of ionic liquids on the structure and function of alcohol dehydrogenase
  78. Evaluation of mutagenesis at position 346 on properties of firefly luciferase by site-directed mutagenesis
  79. The role of surface Arg saturation on thermostability of firefly luciferase from L. turkestanicus
  80. A unique EF-hand motif in mnemiopsin photoprotein from Mnemiopsis leidyi: Implication for its low calcium sensitivity
  81. Comparison of respiratory burst activity and ATP level of blood leukocyte in rain Persian sturgeon (Acipenser persicus) and common carp (Cyprinus carpio)
  82. Design of a Coupled Bioluminescent Assay for a Recombinant Pyruvate Kinase from a Thermophilic Geobacillus
  83. Design of disulfide bridge as an alternative mechanism for color shift in firefly luciferase and development of secreted luciferase
  84. Effects of Sucrose and Trehalose on Stability, Kinetic Properties, and Thermal Aggregation of Firefly Luciferase
  85. EXPRESSION ANALYSIS AND PURIFICATION OF HUMAN RECOMBINANT TISSUE TYPE PLASMINOGEN ACTIVATOR (rt-PA) FROM TRANSGENIC TOBACCO PLANTS
  86. L -carnitine improves oxidative stress and suppressed energy metabolism but not renal dysfunction following release of acute unilateral ureteral obstruction in rat
  87. Molecular enigma of multicolor bioluminescence of firefly luciferase
  88. Design and Characterization of an Aequorin-based Bacterial Biosensor for Detection of Toluene and Related Compounds
  89. RACE-based amplification of cDNA and expression of a luciferin-regenerating enzyme (LRE): An attempt towards persistent bioluminescent signal
  90. The effect of hot-tub therapy on serum Hsp70 level and its benefit on diabetic rats: A preliminary report
  91. Design and introduction of a disulfide bridge in firefly luciferase: increase of thermostability and decrease of pH sensitivity
  92. Relationship between stability and bioluminescence color of firefly luciferase
  93. Roles of trehalose and magnesium sulfate on structural and functional stability of firefly luciferase
  94. Purification and characterization of a thermostable phytate resistant α-amylase from Geobacillus sp. LH8
  95. Restoring 3′–5′ exonuclease activity of thermophilic Geobacillus DNA polymerase I using site-directed mutagenesis in active site
  96. Comparison of the effects of l-carnitine and α-tocopherol on acute ureteral obstruction-induced renal oxidative imbalance and altered energy metabolism in rats
  97. Luciferase protection against proteolytic degradation: A key for improving signal in nano-system biology
  98. Limited Proteolysis of Luciferase as a Reporter in Nanosystem Biology: A Comparative Study
  99. Extensive biodegradation of highly chlorinated biphenyl and Aroclor 1242 by Pseudomonas aeruginosa TMU56 isolated from contaminated soils
  100. The effective role of positive charge saturation in bioluminescence color and thermostability of firefly luciferase
  101. Comparative proteomics analysis of male and female Persian sturgeon (Acipenser persicus) gonads
  102. Effect of Charge Distribution in a Flexible Loop on the Bioluminescence Color of Firefly Luciferases†
  103. Complex I and ATP Content Deficiency in Friedreich's Ataxia
  104. SITE-DIRECTED MUTAGENESIS OF LAMPYRIS TURKESTANICUS LUCIFERASE: THE EFFECT OF CONSERVED RESIDUE(S) IN BIOLUMINESCENCE EMISSION SPECTRA AMONG FIREFLY LUCIFERASES
  105. trinucleotide CAG repeats of the DNA polymerase gene (POLG) in Friedreich’s ataxia patients
  106. Novel Heteroplasmic C13806A Mutation in Friedreich’s Ataxia
  107. Stabilization of firefly luciferase against thermal stress by osmolytes
  108. Delay expression of limonoid UDP-glucosyltransferase makes delayed bitterness in citrus
  109. Site-directed mutagenesis of firefly luciferase: implication of conserved residue(s) in bioluminescence emission spectra among firefly luciferases
  110. Spectroscopic and functional characterization of Lampyris turkestanicus luciferase: a comparative study
  111. Application of zero-length cross-linking to form lysozyme, horseradish peroxidase and lysozyme–peroxidase dimers: Activity and stability
  112. Expression, purification and immobilization of firefly luciferase on alkyl-substituted Sepharose 4B
  113. Digestive proteolytic and amylolytic activities in Trogoderma granarium Everts (Dermestidae: Coleoptera)
  114. Effects of water-miscible solvents and polyhydroxy compounds on the structure and enzymatic activity of thermolysin
  115. Stepwise modification of lysine residues of glucose oxidase with citraconic anhydride
  116. Comparative proteomic analysis of mouse embryonic stem cells and neonatal-derived cardiomyocytes
  117. Acidic and proteolytic digestion of α-amylases from Bacillus licheniformis and Bacillus amyloliquefaciens: Stability and flexibility analysis
  118. Biochemical characterization of alpha-amylase of the Sunn pest, Eurygaster integriceps
  119. Implication of a critical residue (Glu175) in structure and function of bacterial luciferase
  120. Random mutagenesis of bacterial luciferase: critical role of Glu175in the control of luminescence decay
  121. Molecular cloning, sequence analysis, and expression of a cDNA encoding the luciferase from the glow-worm, Lampyris turkestanicus
  122. Chemical modification of glucose oxidase: possible formation of molten globule-like intermediate structure
  123. The Structural and Functional Studies of His119 and His12 in RNase A via Chemical Modification
  124. Partial unfolding of carbonic anhydrase provides a method for its immobilization on hydrophobic adsorbents and protects it against irreversible thermoinactivation
  125. Interaction of Glucose Oxidase With Alkyl-Substituted Sepharose 4B
  126. Adsorptive immobilization of bacterial luciferases on alkyl-substituted Sepharose 4B
  127. Use of Reversible Denaturation for Adsorptive Immobilization of Urease