All Stories

  1. RETRACTED: Di Paola et al. Assessment of 2-Pentadecyl-2-oxazoline Role on Lipopolysaccharide-Induced Inflammation on Early Stage Development of Zebrafish (Danio rerio). Life 2022, 12, 128
  2. Correction: D’Amico et al. Toxic Exposure to Endocrine Disruptors Worsens Parkinson’s Disease Progression through NRF2/HO-1 Alteration. Biomedicines 2022, 10, 1073
  3. Sensory Properties, Redox Characteristics, and Impact on the Hemodynamics of the Flavanol-Rich Fraction Originated Grape and Blueberry
  4. Correction: Casili et al. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC). Cancers 2023, 15, 2796
  5. Correction: D’Amico et al. Consumption of Cashew (Anacardium occidentale L.) Nuts Counteracts Oxidative Stress and Tissue Inflammation in Mild Hyperhomocysteinemia in Rats. Nutrients 2022, 14, 1474
  6. To Go Where Nature Leads: Focus on Palmitoylethanolamide and Related ALIAmides as Innovative Approach to Neuroinflammatory and Pain-Related Disease States in Honor of Doctor Francesco Della Valle
  7. Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential
  8. What Is the Role of Palmitoylethanolamide Co-Ultramicronized with Luteolin on the Symptomatology Reported by Patients Suffering from Long COVID? A Retrospective Analysis Performed by a Group of General Practitioners in a Real-Life Setting
  9. Efficacy of Palmitoylethanolamide and Luteolin Association on Post-Covid Olfactory Dysfunction: A Systematic Review and Meta-Analysis of Clinical Studies
  10. Antioxidant Activity of a Sicilian Almond Skin Extract Using In Vitro and In Vivo Models
  11. Modulation of TLR4/NFκB Pathways in Autoimmune Myocarditis
  12. Modulation of the Proliferative Pathway, Neuroinflammation and Pain in Endometriosis
  13. Current Review of Increasing Animal Health Threat of Per- and Polyfluoroalkyl Substances (PFAS): Harms, Limitations, and Alternatives to Manage Their Toxicity
  14. Aggravation of TGFβ1-Smad Pathway and Autoimmune Myocarditis by Fungicide (Tebuconazole) Exposure
  15. Targeting Nrf2 and NF-κB Signaling Pathways in Inflammatory Pain: The Role of Polyphenols from Thinned Apples
  16. An RNAi-Mediated Reduction in Transcription Factor Nrf-2 Blocks the Positive Effects of Dimethyl Fumarate on Metabolic Stress in Alzheimer’s Disease
  17. Toxic Effects of Gemcitabine and Paclitaxel Combination: Chemotherapy Drugs Exposure in Zebrafish
  18. Inhibition of Fatty Acid Amide Hydrolase (FAAH) Regulates NF-kb Pathways Reducing Bleomycin-Induced Chronic Lung Inflammation and Pulmonary Fibrosis
  19. Baicalein Extract from Chinese Herbal Medicine to Use in Cardiovascular Diseases
  20. The Transcription Factor Nrf2 Mediates the Effects of Antrodia camphorata Extract on Neuropathological Changes in a Mouse Model of Parkinson’s Disease
  21. Effect of Pesticide Vinclozolin Toxicity Exposure on Cardiac Oxidative Stress and Myocardial Damage
  22. Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC)
  23. Redox Imbalance in Neurological Disorders in Adults and Children
  24. Bioactive Compounds of the Mediterranean Diet as Nutritional Support to Fight Neurodegenerative Disease
  25. MemophenolTM Prevents Amyloid-β Deposition and Attenuates Inflammation and Oxidative Stress in the Brain of an Alzheimer’s Disease Rat
  26. Correction: Antonuccio et al. The Nutraceutical N-Palmitoylethanolamide (PEA) Reveals Widespread Molecular Effects Unmasking New Therapeutic Targets in Murine Varicocele. Nutrients 2021, 13, 734
  27. Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury
  28. Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value
  29. The Role of miR-128 in Neurodegenerative Diseases
  30. Endocrine Disruptor Compounds in Environment: Focus on Women’s Reproductive Health and Endometriosis
  31. Recent Emerging Immunological Treatments for Primary Brain Tumors: Focus on Chemokine-Targeting Immunotherapies
  32. Fisetin, a Natural Polyphenol, Ameliorates Endometriosis Modulating Mast Cells Derived NLRP-3 Inflammasome Pathway and Oxidative Stress
  33. Molecular Investigation of DKK3 in Cerebral Ischemic/Reperfusion Injury
  34. Analysis of the Influence of IL-6 and the Activation of the Jak/Stat3 Pathway in Fibromyalgia
  35. Mechanism of Action of Natural Compounds in Peripheral Multiorgan Dysfunction and Hippocampal Neuroinflammation Induced by Sepsis
  36. Cytoprotective and Antioxidant Effects of Hydrolysates from Black Soldier Fly (Hermetia illucens)
  37. Evaluation of the Efficacy of Xyloglucan, Pea Protein and Opuntia ficus-indica Extract in a Preclinical Model of Psoriasis
  38. Hydroxytyrosol and Its Potential Uses on Intestinal and Gastrointestinal Disease
  39. Therapeutic Potential of Dimethyl Fumarate in Counteract Oral Squamous Cell Carcinoma Progression by Modulating Apoptosis, Oxidative Stress and Epithelial–Mesenchymal Transition
  40. Açai Berry Administration Promotes Wound Healing through Wnt/β-Catenin Pathway
  41. Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation
  42. Actaea racemosa L. Rhizome Protect against MPTP-Induced Neurotoxicity in Mice by Modulating Oxidative Stress and Neuroinflammation
  43. Complex Interplay between Autophagy and Oxidative Stress in the Development of Endometriosis
  44. The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors
  45. Protein Kinase Inhibitors as a New Target for Immune System Modulation and Brain Cancer Management
  46. Early Exposure to Environmental Pollutants: Imidacloprid Potentiates Cadmium Toxicity on Zebrafish Retinal Cells Death
  47. Regulation of Apoptosis and Oxidative Stress by Oral Boswellia Serrata Gum Resin Extract in a Rat Model of Endometriosis
  48. A Combination of Xyloglucan, Pea Protein and Chia Seed Ameliorates Intestinal Barrier Integrity and Mucosa Functionality in a Rat Model of Constipation-Predominant Irritable Bowel Syndrome
  49. Açai Berry Attenuates Cyclophosphamide-Induced Damage in Genitourinary Axis-Modulating Nrf-2/HO-1 Pathways
  50. Intratesticular Versus Intrafunicular Lidocaine to Reduce Perioperative Nociception and Immunological Response in Ponies Undergoing Field Castration
  51. Overview on Common Genes Involved in the Onset of Glioma and on the Role of Migraine as Risk Factor: Predictive Biomarkers or Therapeutic Targets?
  52. Modulation of NRF-2 Pathway Contributes to the Therapeutic Effects of Boswellia serrata Gum Resin Extract in a Model of Experimental Autoimmune Myocarditis
  53. Natural Compounds such as Hericium erinaceus and Coriolus versicolor Modulate Neuroinflammation, Oxidative Stress and Lipoxin A4 Expression in Rotenone-Induced Parkinson’s Disease in Mice
  54. Chronic Exposure to Endocrine Disruptor Vinclozolin Leads to Lung Damage Via Nrf2–Nf-kb Pathway Alterations
  55. Chronic Exposure to Vinclozolin Induced Fibrosis, Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Mice Kidney
  56. Trehalose–Carnosine Prevents the Effects of Spinal Cord Injury Through Regulating Acute Inflammation and Zinc(II) Ion Homeostasis
  57. Aerosol-Administered Adelmidrol Attenuates Lung Inflammation in a Murine Model of Acute Lung Injury
  58. Dimethyl Fumarate (DMF) Alleviated Post-Operative (PO) Pain through the N-Methyl-d-Aspartate (NMDA) Receptors
  59. Açai Berry Mitigates Vascular Dementia-Induced Neuropathological Alterations Modulating Nrf-2/Beclin1 Pathways
  60. Adenosine Targeting as a New Strategy to Decrease Glioblastoma Aggressiveness
  61. Impact of Mycotoxin Contaminations on Aquatic Organisms: Toxic Effect of Aflatoxin B1 and Fumonisin B1 Mixture
  62. Snail Mucus Filtrate Reduces Inflammation in Canine Progenitor Epidermal Keratinocytes (CPEK)
  63. Environmental Impact of Pharmaceutical Pollutants: Synergistic Toxicity of Ivermectin and Cypermethrin
  64. Discovering the Effects of Fisetin on NF-κB/NLRP-3/NRF-2 Molecular Pathways in a Mouse Model of Vascular Dementia Induced by Repeated Bilateral Carotid Occlusion
  65. Role of Etanercept and Infliximab on Nociceptive Changes Induced by the Experimental Model of Fibromyalgia
  66. Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion
  67. Environmental Risk Assessment of Dexamethasone Sodium Phosphate and Tocilizumab Mixture in Zebrafish Early Life Stage (Danio rerio)
  68. Environmental Toxicity Assessment of Sodium Fluoride and Platinum-Derived Drugs Co-Exposure on Aquatic Organisms
  69. Toxic Exposure to Endocrine Disruptors Worsens Parkinson’s Disease Progression through NRF2/HO-1 Alteration
  70. Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine
  71. Evaluation of a Gel Containing a Propionibacterium Extract in an In Vivo Model of Wound Healing
  72. Combined Effects of Potassium Perchlorate and a Neonicotinoid on Zebrafish Larvae (Danio rerio)
  73. Environmental Co-Exposure to Potassium Perchlorate and Cd Caused Toxicity and Thyroid Endocrine Disruption in Zebrafish Embryos and Larvae (Danio rerio)
  74. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation
  75. Toxic Effects of Endocrine Disruptor Exposure on Collagen-Induced Arthritis
  76. Role of Bevacizumab on Vascular Endothelial Growth Factor in Apolipoprotein E Deficient Mice after Traumatic Brain Injury
  77. Resveratrol Inhibition of the WNT/β-Catenin Pathway following Discogenic Low Back Pain
  78. Consumption of Cashew (Anacardium occidentale L.) Nuts Counteracts Oxidative Stress and Tissue Inflammation in Mild Hyperhomocysteinemia in Rats
  79. Sensitivity of Zebrafish Embryogenesis to Risk of Fotemustine Exposure
  80. Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury
  81. The Biological Function of MicroRNAs in Bone Tumors
  82. Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model
  83. Coriolus Versicolor Downregulates TLR4/NF-κB Signaling Cascade in Dinitrobenzenesulfonic Acid-Treated Mice: A Possible Mechanism for the Anti-Colitis Effect
  84. Environmental Risk Assessment of Oxaliplatin Exposure on Early Life Stages of Zebrafish (Danio rerio)
  85. Evaluation of Betacoronavirus OC43 and SARS-CoV-2 Elimination by Zefero Air Sanitizer Device in a Novel Laboratory Recirculation System
  86. Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance
  87. Assessment of 2-Pentadecyl-2-oxazoline Role on Lipopolysaccharide-Induced Inflammation on Early Stage Development of Zebrafish (Danio rerio)
  88. Intestinal Disorder in Zebrafish Larvae (Danio rerio): The Protective Action of N-Palmitoylethanolamide-oxazoline
  89. Mineral Composition in Delactosed Dairy Products: Quality and Safety Status
  90. Combined Toxicity of Xenobiotics Bisphenol A and Heavy Metals on Zebrafish Embryos (Danio rerio)
  91. Wnt/β-Catenin Pathway in Experimental Model of Fibromyalgia: Role of Hidrox®
  92. Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer’s Disease
  93. Ultramicronized Palmitoylethanolamide in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation
  94. Aflatoxin B1 Toxicity in Zebrafish Larva (Danio rerio): Protective Role of Hericium erinaceus
  95. Evaluating the Protective Properties of a Xyloglucan-Based Nasal Spray in a Mouse Model of Allergic Rhinitis
  96. Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO−1 and NF-kB Pathways
  97. Effect of Cannabidiol (CBD) on Canine Inflammatory Response: An Ex Vivo Study on LPS Stimulated Whole Blood
  98. The Protective Effect of Snail Secretion Filtrate in an Experimental Model of Excisional Wounds in Mice
  99. Co-Ultra PEALut Enhances Endogenous Repair Response Following Moderate Traumatic Brain Injury
  100. Atrazine Inhalation Causes Neuroinflammation, Apoptosis and Accelerating Brain Aging
  101. KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation
  102. Poly (ADP-Ribose) Polymerase Inhibitor, ABT888, Improved Cisplatin Effect in Human Oral Cell Carcinoma
  103. Hidrox ® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain
  104. Epigallocatechin-3-Gallate Modulates Postoperative Pain by Regulating Biochemical and Molecular Pathways
  105. Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia
  106. Inhibition of P2X7 Purinergic Receptor Ameliorates Fibromyalgia Syndrome by Suppressing NLRP3 Pathway
  107. Hericium erinaceus and Coriolus versicolor Modulate Molecular and Biochemical Changes after Traumatic Brain Injury
  108. Regulation of Inflammatory and Proliferative Pathways by Fotemustine and Dexamethasone in Endometriosis
  109. Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach
  110. Hidrox® Roles in Neuroprotection: Biochemical Links between Traumatic Brain Injury and Alzheimer’s Disease
  111. Hidrox® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model
  112. Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis
  113. Hidrox® and Endometriosis: Biochemical Evaluation of Oxidative Stress and Pain
  114. Role of miRNA-19a in Cancer Diagnosis and Poor Prognosis
  115. The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways
  116. PEA-OXA Mitigates Oxaliplatin-Induced Painful Neuropathy through NF-κB/Nrf-2 Axis
  117. Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update
  118. Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas
  119. PEA/Polydatin: Anti-Inflammatory and Antioxidant Approach to Counteract DNBS-Induced Colitis
  120. The Nutraceutical N-Palmitoylethanolamide (PEA) Reveals Widespread Molecular Effects Unmasking New Therapeutic Targets in Murine Varicocele
  121. Effect of Ultra-Micronized-Palmitoylethanolamide and Acetyl-l-Carnitine on Experimental Model of Inflammatory Pain
  122. Plumericin Protects against Experimental Inflammatory Bowel Disease by Restoring Intestinal Barrier Function and Reducing Apoptosis
  123. Involvements of Hyperhomocysteinemia in Neurological Disorders
  124. TAK1 Inhibitor Enhances the Therapeutic Treatment for Glioblastoma
  125. Role of Fibroblast Growth Factors Receptors (FGFRs) in Brain Tumors, Focus on Astrocytoma and Glioblastoma
  126. TLR7/8 in the Pathogenesis of Parkinson’s Disease
  127. Protective Effect of Silibinin on Lipopolysaccharide-Induced Inflammatory Responses in Equine Peripheral Blood Mononuclear Cells, an In Vitro Study
  128. Protective effects of Colomast®, A New Formulation of Adelmidrol and Sodium Hyaluronate, in A Mouse Model of Acute Restraint Stress
  129. Protective Effect of Hydroxytyrosol on LPS-Induced Inflammation and Oxidative Stress in Bovine Endometrial Epithelial Cell Line
  130. Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats
  131. Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor as a Novel Therapeutic Tool for Lung Injury
  132. The Protective Effects of Pre- and Post-Administration of Micronized Palmitoylethanolamide Formulation on Postoperative Pain in Rats
  133. Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein
  134. Synergic Therapeutic Potential of PEA-Um Treatment and NAAA Enzyme Silencing In the Management of Neuroinflammation
  135. Dietary Supplementation with Palmitoyl-Glucosamine Co-Micronized with Curcumin Relieves Osteoarthritis Pain and Benefits Joint Mobility
  136. Novel Combination of COX-2 Inhibitor and Antioxidant Therapy for Modulating Oxidative Stress Associated with Intestinal Ischemic Reperfusion Injury and Endotoxemia
  137. Anti-inflammatory and Anti-oxidant Activity of Hidrox® in Rotenone-Induced Parkinson’s Disease in Mice
  138. Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury
  139. Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report
  140. Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury
  141. ALIAmides Update: Palmitoylethanolamide and Its Formulations on Management of Peripheral Neuropathic Pain
  142. Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema
  143. Protective Effect of Epigallocatechin-3-Gallate (EGCG) in Diseases with Uncontrolled Immune Activation: Could Such a Scenario Be Helpful to Counteract COVID-19?
  144. Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model
  145. Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis
  146. Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing
  147. Focus on the Role of NLRP3 Inflammasome in Diseases
  148. Effect of a Product Containing Xyloglucan and Pea Protein on a Murine Model of Atopic Dermatitis
  149. Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat
  150. The Role of Annexin A1 and Formyl Peptide Receptor 2/3 Signaling in Chronic Corticosterone-Induced Depression-Like behaviors and Impairment in Hippocampal-Dependent Memory
  151. The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate
  152. Management of Traumatic Brain Injury: From Present to Future
  153. Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome
  154. The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis
  155. An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events
  156. The Protective Effect of New Carnosine-Hyaluronic Acid Conjugate on the Inflammation and Cartilage Degradation in the Experimental Model of Osteoarthritis
  157. N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice
  158. Protective Effect of New Formulation of Carnosine+Hyaluronic Acid on the Inflammation and Cartilage Degradation in the Experimental Model of Osteoarthritis
  159. Co-ultraPEALut: Role in Preclinical and Clinical Delirium Manifestations
  160. Melatonin Plus Folic Acid Treatment Ameliorates Reserpine-Induced Fibromyalgia: An Evaluation of Pain, Oxidative Stress, and Inflammation
  161. The neuroprotective effects of micronized PEA (PEA-m) formulation on diabetic peripheral neuropathy in mice
  162. N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway
  163. Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets
  164. Interferon Alpha Has a Strong Anti-tumor Effect in Philadelphia-negative Myeloproliferative Neoplasms
  165. Susceptibility of erythrocytes from different sources to xenobiotics-induced lysis
  166. N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion
  167. A randomized, controlled, phase II clinical trial of β‐D‐mannuronic acid (M2000) in pre‐surgical breast cancer patients at early stage (T1‐T2)
  168. Neutrophil elastase plays a non‐redundant role in remodeling the venular basement membrane and neutrophil diapedesis post‐ischemia/reperfusion injury
  169. Correction to “Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect
  170. Role of Metabotropic Glutamate Receptors in Neurological Disorders
  171. Involvement of TLR4 and PPAR-α Receptors in Host Response and NLRP3 Inflammasome Activation, Against Pulmonary Infection With Pseudomonas Aeruginosa
  172. Multidisciplinary approach to prostatitis
  173. The association of adelmidrol with sodium hyaluronate displays beneficial properties against bladder changes following spinal cord injury in mice
  174. Treatment With a Flavonoid-Rich Fraction of Bergamot Juice Improved Lipopolysaccharide-Induced Periodontitis in Rats
  175. International multicenter randomized, placebo-controlled phase III clinical trial of β-d-mannuronic acid in rheumatoid arthritis patients
  176. Formyl peptide receptor 1 signalling promotes experimental colitis in mice
  177. Pharmacodynamical effects of orally administered exenatide nanoparticles embedded in gastro-resistant microparticles
  178. Selective CB2 inverse agonist JTE907 drives T cell differentiation towards a Treg cell phenotype and ameliorates inflammation in a mouse model of inflammatory bowel disease
  179. TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson’s diseases in vivo model
  180. Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis
  181. AST-120 Reduces Neuroinflammation Induced by Indoxyl Sulfate in Glial Cells
  182. Effect of pea protein plus grape seed dry extract on a murine model of Candida albicans induced vaginitis
  183. Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury
  184. Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush
  185. Effects of a new compound containing Palmitoylethanolamide and Baicalein in Myocardial Ischaemia/Reperfusion Injury in VIVO
  186. Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18
  187. Topical Application of Adelmidrol + Trans-Traumatic Acid Enhances Skin Wound Healing in a Streptozotocin-Induced Diabetic Mouse Model
  188. Micronized palmitoylethanolamide reduces joint pain and glial cell activation
  189. Laser-generated bismuth nanoparticles for applications in imaging and radiotherapy
  190. Adelmidrol + sodium hyaluronate in IC/BPS or conditions associated to chronic urothelial inflammation. A translational study
  191. Correction: Effect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome
  192. Lung resident mesenchymal cells isolated from patients with the Bronchiolitis Obliterans Syndrome display a deregulated epigenetic profile
  193. Absence of formyl peptide receptor 1 causes endometriotic lesion regression in a mouse model of surgically-induced endometriosis
  194. Dimethyl Fumarate Attenuates Neuroinflammation and Neurobehavioral Deficits Induced by Experimental Traumatic Brain Injury
  195. Sphingosine 1-Phosphate Receptor Subtype 1 as a Therapeutic Target for Brain Trauma
  196. Protective Effects of Xyloglucan in Association with the Polysaccharide Gelose in an Experimental Model of Gastroenteritis and Urinary Tract Infections
  197. Evaluation of the Effect of a-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property
  198. Anti-inflammatory effect of ATB-352, a H2S −releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats
  199. A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-d-mannuronic acid in rheumatoid arthritis patients
  200. Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH)
  201. 2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease
  202. Oral administration effects of β- d -mannuronic acid (M2000) on Th17 and regulatory T cells in patients with ankylosing spondylitis
  203. Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect
  204. N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice
  205. Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer’s disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms
  206. Neuronal-like differentiated SH-SY5Y cells adaptation to a mild and transient H2 O2 -induced oxidative stress
  207. The Antioxidant Activity of Pistachios Reduces Cardiac Tissue Injury of Acute Ischemia/Reperfusion (I/R) in Diabetic Streptozotocin (STZ)-Induced Hyperglycaemic Rats
  208. Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis
  209. Bendamustine plus Rituximab Versus R‐CHOP as First‐Line Treatment for Patients with Follicular Lymphoma Grade 3A: Evidence from a Multicenter, Retrospective Study
  210. Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: A 12-week randomized, placebo-controlled, phase I/II clinical trial
  211. A Controlled Cortical Impact Preclinical Model of Traumatic Brain Injury
  212. An In Vivo Compression Model of Spinal Cord Injury
  213. Middle Cerebral Artery Occlusion by an Intraluminal Suture Method
  214. Fumaric Acid Esters Attenuate Secondary Degeneration after Spinal Cord Injury
  215. Multiple mechanisms of dimethyl fumarate in amyloid β-induced neurotoxicity in human neuronal cells
  216. Introduction of β- d -mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression
  217. N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury
  218. The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2
  219. Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury
  220. The Anti-Inflammatory and Antioxidant Potential of Pistachios (Pistacia vera L.) In Vitro and In Vivo
  221. The effects of β-d-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line
  222. AQX‐1125, small molecule SHIP1 activator inhibits bleomycin‐induced pulmonary fibrosis
  223. The Potent Inhibitory Effect of β-D-Mannuronic Acid (M2000) as a Novel NSAID with Immunosuppressive Property on Anti-Cyclic Citrullinated Peptide Antibodies, Rheumatoid Factor and Anti-dsDNA Antibodies in Patients with Rheumatoid Arthritis
  224. A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models
  225. Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia
  226. Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia
  227. Effect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome
  228. Anti-Inflammatory and Neuroprotective Effects of Co-UltraPEALut in a Mouse Model of Vascular Dementia
  229. 2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation
  230. Inhibition of inflammasome activation improves lung acute injury induced by carrageenan in a mouse model of pleurisy
  231. Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect
  232. Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson’s disease
  233. Neuroprotective Effects of Temsirolimus in Animal Models of Parkinson’s Disease
  234. Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases
  235. A flavonoid-rich extract of orange juice reduced oxidative stress in an experimental model of inflammatory bowel disease
  236. Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity
  237. FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury
  238. Laser-produced Au nanoparticles as X-ray contrast agents for diagnostic imaging
  239. Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression
  240. Adelmidrol, in combination with hyaluronic acid, displays increased anti-inflammatory and analgesic effects against monosodium iodoacetate-induced osteoarthritis in rats
  241. Hormesis, cellular stress response and neuroinflammation in schizophrenia: Early onset versus late onset state
  242. Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease
  243. Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation
  244. Co-micronized Palmitoylethanolamide/Polydatin Treatment Causes Endometriotic Lesion Regression in a Rodent Model of Surgically Induced Endometriosis
  245. Traumatic Brain Injury Leads to Development of Parkinson's Disease Related Pathology in Mice
  246. Beneficial Effects of Co-Ultramicronized Palmitoylethanolamide/Luteolin in a Mouse Model of Autism and in a Case Report of Autism
  247. PPAR-α Modulates the Anti-Inflammatory Effect of Melatonin in the Secondary Events of Spinal Cord Injury
  248. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease
  249. PARP inhibition treatment in a nonconventional experimental mouse model of chronic asthma
  250. Ultramicronized palmitoylethanolamide (PEA-um ® ) in the treatment of idiopathic pulmonary fibrosis
  251. Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) in Myocardial Ischaemia and Reperfusion Injury in VIVO
  252. Anti-inflammatory and Antioxidant Effects of Flavonoid-Rich Fraction of Bergamot Juice (BJe) in a Mouse Model of Intestinal Ischemia/Reperfusion Injury
  253. Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer’s disease pathogenesis
  254. Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Is It a Valid Treatment Option?
  255. A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation
  256. Everolimus improves memory and learning while worsening depressive- and anxiety-like behavior in an animal model of depression
  257. Thyroid hormone autoantibodies: are they a better marker to detect early thyroid damage in patients with hematologic cancers receiving tyrosine kinase inhibitor or immunoregulatory drug treatments?
  258. 2-pentadecyl-2-oxazoline: Identification in coffee, synthesis and activity in a rat model of carrageenan-induced hindpaw inflammation
  259. Erratum to: A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury
  260. Erratum to: Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain
  261. B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury
  262. The antioxidative property of melatonin against brain ischemia
  263. Erratum to: Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice
  264. Bendamustine plus rituximab versus R-CHOP as first-line treatment for patients with indolent non-Hodgkin’s lymphoma: evidence from a multicenter, retrospective study
  265. Neuroinflammation and Immunity: A New Pharmacological Target in Depression
  266. Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis
  267. KU0063794, a Dual mTORC1 and mTORC2 Inhibitor, Reduces Neural Tissue Damage and Locomotor Impairment After Spinal Cord Injury in Mice
  268. Co-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury
  269. Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer's disease pathogenesis
  270. 90Y-Ibritumomab-Tiuxetan Consolidation Therapy for Advanced-Stage Mantle Cell Lymphoma After First-Line Autologous Stem Cell Transplantation: Is It Time for a Step Forward?
  271. UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness
  272. A novel protective formulation of Palmitoylethanolamide in experimental model of contrast agent induced nephropathy
  273. Repetitive Transcranial Magnetic Stimulation as a Novel Therapy in Animal Models of Traumatic Brain Injury
  274. Neuroprotective Effects of Co-UltraPEALut on Secondary Inflammatory Process and Autophagy Involved in Traumatic Brain Injury
  275. Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to Man
  276. Dimethyl Fumarate Reduces Inflammatory Responses in Experimental Colitis
  277. 90 Y-ibritumomab tiuxetan: a nearly forgotten opportunity
  278. The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease
  279. Extranodal diffuse large B-cell lymphoma with monoclonal gammopathy: an aggressive and primary refractory disease responding to an immunomodulatory agent
  280. Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats
  281. Role of inflammation and apoptosis in multiple sclerosis: Comparative analysis between the periphery and the central nervous system
  282. Role of the Renin-Angiotensin-Aldosterone System and Its Pharmacological Inhibitors in Cardiovascular Diseases: Complex and Critical Issues
  283. Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury
  284. Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion
  285. Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice
  286. The anti-inflammatory effects of palmitoylethanolamide (PEA) on endotoxin-induced uveitis in rats
  287. The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury
  288. Effects of thymosin β4 and its N-terminal fragment Ac-SDKP on TGF-β-treated human lung fibroblasts and in the mouse model of bleomycin-induced lung fibrosis
  289. Emerging pharmacotherapy for treatment of traumatic brain injury: targeting hypopituitarism and inflammation
  290. N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution
  291. Antineuropathic Profile of N-Palmitoylethanolamine in a Rat Model of Oxaliplatin-Induced Neurotoxicity
  292. Inflammatory and Cell Death Pathways in Brain and Peripheral Blood in Parkinson’s Disease
  293. Is radiotherapy still necessary for diffuse large B-cell lymphoma therapy?
  294. Role of natural antioxidants and potential use of bergamot in treating rheumatoid arthritis
  295. Ultramicronized palmitoylethanolamide reduces inflammation an a Th1-mediated model of colitis
  296. Long-term betamethasone 21-phosphate disodium treatment has distinct effects in CD1 and DBA/2 mice on animal behavior accompanied by opposite effects on neurogenesis
  297. Emerging drugs for acute lung injury
  298. Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain
  299. Neuroprotection by Association of Palmitoylethanolamide with Luteolin in Experimental Alzheimer’s Disease Models: The Control of Neuroinflammation
  300. A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways
  301. Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice
  302. Pim kinases in hematological malignancies: where are we now and where are we going?
  303. Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain
  304. Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury
  305. Phosphodiesterase as a New Therapeutic Target for the Treatment of Spinal Cord Injury and Neurodegenerative Diseases
  306. Reply to Letter to Editor: “Kriek R., Marketing messages in pharmacological papers and scientific chapters: The case of palmitoylethanolamide and its formulations” [Pharmacol Res (2014) 10.1016/j.phrs.2014.04.007]
  307. Osteoporosis and alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling
  308. Abandon the Mouse Research Ship? Not Just Yet!
  309. Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice
  310. The Development and Maintenance of Paclitaxel-induced Neuropathic Pain Require Activation of the Sphingosine 1-Phosphate Receptor Subtype 1
  311. Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice
  312. N-Palmitoylethanolamine Administration Ameliorates the Clinical Manifestation and Progression of Experimental Autoimmune Encephalomyelitis in Rodents
  313. Pelagia noctiluca (Scyphozoa) Crude Venom Injection Elicits Oxidative Stress and Inflammatory Response in Rats
  314. Targeting inflammation: New therapeutic approaches in chronic kidney disease (CKD)
  315. Inflammation and Programmed Cell Death in Alzheimer’s Disease: Comparison of the Central Nervous System and Peripheral Blood
  316. Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies
  317. Role of melatonin supplementation in neurodegenerative disorders
  318. Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice
  319. Effects of Palmitoylethanolamide and Luteolin in an Animal Model of Anxiety/Depression
  320. Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase
  321. Fluridone as a new anti-inflammatory drug
  322. Targeting selectins for the treatment of inflammatory diseases
  323. Neuroimmune Pharmacology: An Emerging Discipline for the Italian Society of Pharmacology
  324. Traumatic Brain Injury: Oxidative Stress and Neuroprotection
  325. A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury
  326. A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury
  327. n-3 Fatty Acids: Role in Neurogenesis and Neuroplasticity
  328. Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance
  329. mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy
  330. NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice
  331. Post-ischaemic thyroid hormone treatment in a rat model of acute stroke
  332. Effect of Almond Skins on a Lung Injury Model Elicited by Multirug-Resistant Pseudomonas Aeruginosa
  333. Exogenous T3 administration provides neuroprotection in a murine model of traumatic brain injury
  334. Absence of TLR4 Reduces Neurovascular Unit and Secondary Inflammatory Process after Traumatic Brain Injury in Mice
  335. Combination therapy with melatonin and dexamethasone in a mouse model of traumatic brain injury
  336. Palmitoylethanolamide in Homeostatic and Traumatic Central Nervous System Injuries
  337. Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma
  338. Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism
  339. Thymosin β4 protects C57BL/6 mice from bleomycin-induced damage in the lung
  340. Green Tea
  341. Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes
  342. The renal injury and inflammation caused by ischemia–reperfusion are reduced by genetic inhibition of TNF-αR1: A comparison with infliximab treatment
  343. Effects of a polyphenol present in olive oil, oleuropein aglycone, in a murine model of intestinal ischemia/reperfusion injury
  344. Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice
  345. PALMITOYLETHANOLAMIDE REDUCES EARLY RENAL DYSFUNCTION AND INJURY CAUSED BY EXPERIMENTAL ISCHEMIA AND REPERFUSION IN MICE
  346. Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats
  347. Neuroprotective Activities of Palmitoylethanolamide in an Animal Model of Parkinson's Disease
  348. Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors
  349. Peroxisome proliferator-activated receptor β/δ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice
  350. Effect of Fasudil, a Selective Inhibitor of Rho Kinase Activity, in the Secondary Injury Associated with the Experimental Model of Spinal Cord Trauma
  351. In vitro and in vivo properties of a fully human IgG1 monoclonal antibody that combats multidrug resistant Pseudomonas aeruginosa
  352. Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice
  353. Targeting the Overproduction of Peroxynitrite for the Prevention and Reversal of Paclitaxel-Induced Neuropathic Pain
  354. The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice
  355. Pharmacological and clinical overview of cloperastine in treatment of cough
  356. Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury