All Stories

  1. Repurposing of FDA-approved Drugs Identifies Glipizide as a Potent HMG-CoA Reductase Inhibitor: a High-Throughput Virtual Screening and Molecular Dynamics Approach for Targeting Hypercholesterolemia

    Article • Journal of Pharmaceutical Innovation, January 2026, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  2. Ubiquitination of mut-p53 Inhibits Pancreatic Tumor Growth

    Article • Molecular Cancer Therapeutics, November 2025, American Association for Cancer Research (AACR)

    Dr. Sahir Sultan Alvi

  3. Anti-breast cancer potential of fluoro-containing triazole-synthesized hybrid molecules: In-vitro screening and Force Field-based molecular dynamics approach

    Article • Next Research, September 2025, Elsevier

    Dr. Sahir Sultan Alvi

  4. Mitochondrial ribosomal protein L3 (MRPL3): An early diagnostic biomarker and potential molecular target in pancreatic cancer

    Article • Translational Oncology, August 2025, Elsevier

    Dr. Sahir Sultan Alvi

  5. Honey Targets Ribosome Biogenesis Components to Suppress the Growth of Human Pancreatic Cancer Cells

    Article • Cancers, October 2024, MDPI AG

    Dr. Sahir Sultan Alvi

  6. Medicinal significance of sp2/sp3 hybridized at C-3-substituted indole-containing lead molecules and FDA-approved drugs

    Article • Medicinal Chemistry Research, September 2024, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  7. Organosulfur Compounds, S‐Allyl‐L‐Cysteine and S‐Ethyl‐L‐Cysteine, Target PCSK‐9/LDL‐R‐Axis to Ameliorate Cardiovascular, Hepatic, and Metabolic Changes in High Carbohydrate and High Fat Diet‐Induced Metabolic Syndro...

    Article • Phytotherapy Research, September 2024, Wiley

    Dr. Sahir Sultan Alvi

  8. Targeting SARS-CoV-2 main protease (Mpro) and human ACE-2: A virtual screening of carotenoids and polyphenols from tomato (Solanum lycopersicum L.) to combat Covid-19

    Article • Intelligent Pharmacy, February 2024, Elsevier

    Dr. Sahir Sultan Alvi

  9. Association of PCSK-9 with the Biomarkers of Type-2 Diabetes and its Complications in the Indian Population: a Pilot Study

    Article • Clinical Laboratory, January 2024, Clinical Laboratory Publications

    Dr. Sahir Sultan Alvi

  10. Assessment of the mechanical and durability characteristics of bio-mineralized Bacillus subtilis self-healing concrete blended with hydrated lime and brick powder

    Article • Case Studies in Construction Materials, December 2023, Elsevier

    Dr. Sahir Sultan Alvi

  11. Naturally occurring organosulfur compounds effectively inhibits PCSK-9 activity and restrict PCSK-9-LDL-receptor interaction via in-silico and in-vitro approach

    Article • Natural Product Research, October 2023, Taylor & Francis

    Dr. Sahir Sultan Alvi

  12. Novel Functionalized Spiro [Indoline-3,5′-pyrroline]-2,2′dione Derivatives: Synthesis, Characterization, Drug-Likeness, ADME, and Anticancer Potential

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Mohd Asif , Dr. Sahir Sultan Alvi

  13. Abstract 4427: Cucurbitacin B: A promising drug candidate for targeting tumor immunosuppressive cells

    Article • Cancer Research, April 2023, American Association for Cancer Research (AACR)

    Dr. Sahir Sultan Alvi

  14. Association of circulatory PCSK-9 with biomarkers of redox imbalance and inflammatory cascades in the prognosis of diabetes and associated complications: a pilot study in the Indian population

    Article • Free Radical Research, April 2023, Taylor & Francis

    Dr. Sahir Sultan Alvi

  15. Triphala extract for the treatment of gastric ulcers and oxidative stress in rats.

    Article • January 2023, Indian Pharmaceutical Association - IPA

    Dr. Sahir Sultan Alvi

  16. Berberis aristata and its secondary metabolites: Insights into nutraceutical and therapeutical applications

    Article • Pharmacological Research - Modern Chinese Medicine, December 2022, Elsevier

    Dr. Sahir Sultan Alvi

  17. Target-Based Virtual and Biochemical Screening Against HMG-CoA Reductase Reveals Allium sativum-Derived Organosulfur Compound N-Acetyl Cysteine as a Cardioprotective Agent

    Article • Revista Brasileira de Farmacognosia, October 2022, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  18. Carvacrol protects against carbonyl osmolyte-induced structural modifications and aggregation to serum albumin: Insights from physicochemical and molecular interaction studies

    Article • International Journal of Biological Macromolecules, July 2022, Elsevier

    Dr. Sahir Sultan Alvi

  19. Correction to: Identification and evaluation of natural organosulfur compounds as potential dual inhibitors of α-amylase and α-glucosidase activity: an in-silico and in-vitro approach

    Article • Medicinal Chemistry Research, October 2021, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  20. Identification and evaluation of natural organosulfur compounds as potential dual inhibitors of α-amylase and α-glucosidase activity: an in-silico and in-vitro approach

    Article • Medicinal Chemistry Research, September 2021, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  21. Ezetimibe attenuates experimental diabetes and renal pathologies via targeting the advanced glycation, oxidative stress and AGE-RAGE signalling in rats

    Article • Archives of Physiology and Biochemistry, January 2021, Taylor & Francis

    Dr. Sahir Sultan Alvi

  22. Glycyrrhizic Acid Scavenges Reactive Carbonyl Species and Attenuates Glycation‐Induced Multiple Protein Modification: An In Vitro and In Silico Study

    Article • Oxidative Medicine and Cellular Longevity, January 2021, Wiley

    Dr. Sahir Sultan Alvi

  23. Amelioration of neuropilin-1 and RAGE/matrix metalloproteinase-2 pathway-induced renal injury in diabetic rats by rosuvastatin

    Article • Archives of Biological Sciences, January 2021, National Library of Serbia

    Dr. Sahir Sultan Alvi

  24. Insights into pharmacological mechanisms of polydatin in targeting risk factors-mediated atherosclerosis

    Article • Life Sciences, August 2020, Elsevier

    Dr. Sahir Sultan Alvi

  25. A biochemical & biophysical study on in-vitro anti-glycating potential of iridin against d-Ribose modified BSA

    Article • Archives of Biochemistry and Biophysics, June 2020, Elsevier

    Dr. Sahir Sultan Alvi

  26. Phyllanthus virgatus forst against oxidative stress and retino-nephropathy in diabetic rats

    Article • Pakistan Journal of Pharmaceutical Sciences, November 2019, Faculty of Pharmacy and Pharmaceutical Sciences, University of Karachi

    Dr. Sahir Sultan Alvi

  27. Modulatory role of HMG-CoA reductase inhibitors and ezetimibe on LDL-AGEs-induced ROS generation and RAGE-associated signalling in HEK-293 Cells

    Article • Life Sciences, October 2019, Elsevier

    Dr. Sahir Sultan Alvi

  28. Therapeutic efficacy of Boerhaavia diffusa (Linn.) root methanolic extract in attenuating streptozotocin-induced diabetes, diabetes-linked hyperlipidemia and oxidative-stress in rats

    Article • Biomedical Research and Therapy, July 2019, Biomedical Research and Therapy

    Dr. Sahir Sultan Alvi

  29. Ginkgolide B Mediated Alleviation of Inflammatory Cascades and Altered Lipid Metabolism in HUVECs via Targeting PCSK-9 Expression and Functionality

    Article • BioMed Research International, June 2019, Hindawi Publishing Corporation

    Dr. Sahir Sultan Alvi

  30. Glycation and HMG-CoA Reductase Inhibitors: Implication in Diabetes and Associated Complications

    Article • Current Diabetes Reviews, April 2019, Bentham Science Publishers

    Dr. Sahir Sultan Alvi, Saheem Ahmad

  31. Natural organosulfur compounds and cardiovascular diseases

    Article • January 2019, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  32. Rosemary and neurological disorders.

    Article • January 2019, Springer Science + Business Media

    Dr. Sahir Sultan Alvi

  33. Antiglycation study of HMG-R inhibitors and tocotrienol against glycated BSA and LDL: A comparative study

    Article • International Journal of Biological Macromolecules, September 2018, Elsevier

    Dr. Sahir Sultan Alvi, Professor Rizwan Hasan Khan

  34. Lycopene amends LPS induced oxidative stress and hypertriglyceridemia via modulating PCSK-9 expression and Apo-CIII mediated lipoprotein lipase activity

    Article • Biomedicine & Pharmacotherapy, December 2017, Elsevier

    Sahir Sultan Alvi, Dr. Sahir Sultan Alvi

  35. Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia

    Article • Free Radical Biology and Medicine, July 2017, Elsevier

    IRFAN ANSARI, Sahir Sultan Alvi, Dr. Sahir Sultan Alvi

  36. Molecular rationale delineating the role of lycopene as a potent HMG-CoA reductase inhibitor:in vitroandin silicostudy

    Article • Natural Product Research, November 2015, Taylor & Francis

    Sahir Sultan Alvi, Dr. Sahir Sultan Alvi