All Stories

  1. Assessing the Interactions between Snake Venom Metalloproteinases and Hydroxamate Inhibitors Using Kinetic and ITC Assays, Molecular Dynamics Simulations and MM/PBSA-Based Scoring Functions

    Article • ACS Omega, December 2024, American Chemical Society (ACS)

    Dr Ronaldo Alves Pinto Nagem

  2. Tunable Surface Plasmon-Polaritons Interaction in All-Metal Pyramidal Metasurfaces: Unveiling Principles and Significance for Biosensing Applications

    Article • ACS Applied Optical Materials, July 2024, American Chemical Society (ACS)

    Dr Ronaldo Alves Pinto Nagem

  3. New Approaches to the Prevention of Visceral Leishmaniasis: A Review of Recent Patents of Potential Candidates for a Chimeric Protein Vaccine

    Article • Vaccines, March 2024, MDPI AG

    Dr Ronaldo Alves Pinto Nagem

  4. Proteus: An algorithm for proposing stabilizing mutation pairs based on interactions observed in known protein 3D structures

    Article • BMC Bioinformatics, July 2020, Springer Science + Business Media

    Dr Ronaldo Alves Pinto Nagem

  5. Structural and immunological characterization of a new nucleotidyltransferase-like antigen from Paracoccidioides brasiliensis

    Article • Molecular Immunology, August 2019, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  6. Benzimidazole inhibitors of the major cysteine protease of Trypanosoma brucei

    Article • Future Medicinal Chemistry, July 2019, Future Science

    Dr Ronaldo Alves Pinto Nagem

  7. Catalytic mechanism for the conversion of salicylate into catechol by the flavin-dependent monooxygenase salicylate hydroxylase

    Article • International Journal of Biological Macromolecules, January 2019, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  8. Evaluation of three recombinant proteins for the development of ELISA and immunochromatographic tests for visceral leishmaniasis serodiagnosis

    Article • Memórias do Instituto Oswaldo Cruz, January 2019, FapUNIFESP (SciELO)

    Dr Ronaldo Alves Pinto Nagem

  9. The in vivo and in vitro roles of Trypanosoma cruzi Rad51 in the repair of DNA double strand breaks and oxidative lesions

    Article • PLoS Neglected Tropical Diseases, November 2018, PLOS

    Dr Ronaldo Alves Pinto Nagem

  10. Biochemical analysis and identification of linear B-cell epitopes from recombinant Sm21.7 antigen from Schistosoma mansoni

    Article • Molecular Immunology, September 2018, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  11. A combined approach for enhancing the stability of recombinant cis -dihydrodiol naphthalene dehydrogenase from Pseudomonas putida G7 allowed for the structural and kinetic characterization of the enzyme

    Article • Protein Expression and Purification, April 2017, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  12. Effect of ionizing radiation exposure on Trypanosoma cruzi ubiquitin-proteasome system

    Article • Molecular and Biochemical Parasitology, March 2017, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  13. Characterization and biotechnological application of recombinant xylanases from Aspergillus nidulans

    Article • International Journal of Biological Macromolecules, October 2016, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  14. Structural and Kinetic Properties of the Aldehyde Dehydrogenase NahF, a Broad Substrate Specificity Enzyme for Aldehyde Oxidation

    Article • Biochemistry, September 2016, American Chemical Society (ACS)

    Dr Ronaldo Alves Pinto Nagem

  15. Protective antibodies against a sphingomyelinase D from Loxosceles intermedia spider venom elicited in mice with different genetic background

    Article • Vaccine, July 2016, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  16. Crystal Structures of Apo and Liganded 4-Oxalocrotonate Decarboxylase Uncover a Structural Basis for the Metal-Assisted Decarboxylation of a Vinylogous β-Keto Acid

    Article • Biochemistry, May 2016, American Chemical Society (ACS)

    Dr Ronaldo Alves Pinto Nagem

  17. Unraveling the distinctive features of hemorrhagic and non-hemorrhagic snake venom metalloproteinases using molecular simulations

    Article • Journal of Computer-Aided Molecular Design, December 2015, Springer Science + Business Media

    Dr Ronaldo Alves Pinto Nagem

  18. Structural and kinetic characterization of recombinant 2-hydroxymuconate semialdehyde dehydrogenase from Pseudomonas putida G7

    Article • Archives of Biochemistry and Biophysics, August 2015, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  19. Evaluation of three recombinant Leishmania infantum antigens in human and canine visceral leishmaniasis diagnosis

    Article • Acta Tropica, September 2014, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  20. Mapping B-Cell Epitopes for the Peroxidoxin of Leishmania (Viannia) braziliensis and Its Potential for the Clinical Diagnosis of Tegumentary and Visceral Leishmaniasis

    Article • PLoS ONE, June 2014, PLOS

    Dr Ricardo T Fujiwara, Dr Ronaldo Alves Pinto Nagem

  21. Preliminary crystallographic studies of aSchistosoma mansoniantigen (Sm21.7) dynein light-chain (DLC) domain

    Article • Acta Crystallographica Section F Structural Biology Communications, May 2014, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  22. Epitope Mapping of the HSP83.1 Protein of Leishmania braziliensis Discloses Novel Targets for Immunodiagnosis of Tegumentary and Visceral Clinical Forms of Leishmaniasis

    Article • Clinical and Vaccine Immunology, May 2014, ASM Journals

    Dr Ronaldo Alves Pinto Nagem

  23. Identification of Differentially Expressed Proteins from Leishmania amazonensis Associated with the Loss of Virulence of the Parasites

    Article • PLoS Neglected Tropical Diseases, April 2014, PLOS

    Dr Miguel Angel Chávez Fumagalli, Dr Ronaldo Alves Pinto Nagem

  24. Antigenicity and Protective Efficacy of a Leishmania Amastigote-specific Protein, Member of the Super-oxygenase Family, against Visceral Leishmaniasis

    Article • PLoS Neglected Tropical Diseases, March 2013, PLOS

    Dr Miguel Angel Chávez Fumagalli, Dr Ronaldo Alves Pinto Nagem

  25. X-ray crystal structure of CMS1MS2: a high proteolytic activity cysteine proteinase from Carica candamarcensis

    Article • Amino Acids, May 2012, Springer Science + Business Media

    Dr Ronaldo Alves Pinto Nagem

  26. Expression, purification and preliminary crystallographic studies of NahF, a salicylaldehyde dehydrogenase fromPseudomonas putidaG7 involved in naphthalene degradation

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, December 2011, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  27. Structural binding evidence of the trypanocidal drugs Berenil® and Pentacarinate® active principles to a serine protease model

    Article • International Journal of Biological Macromolecules, June 2010, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  28. Spectroscopic and thermodynamic properties of Debaryomyces hansenii UFV-1 α-galactosidases

    Article • International Journal of Biological Macromolecules, April 2010, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  29. Complete amino-acid sequence, crystallization and preliminary X-ray diffraction studies of leucurolysin-a, a nonhaemorrhagic metalloproteinase fromBothrops leucurussnake venom

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2009, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  30. Purification, crystallization and preliminary X-ray analysis of CMS1MS2: a cysteine proteinase fromCarica candamarcensislatex

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2008, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  31. Structure of Xanthomonas axonopodis pv. citri YaeQ reveals a new compact protein fold built around a variation of the PD-(D/E)XK nuclease motif

    Article • Proteins Structure Function and Bioinformatics, July 2007, Wiley

    Dr Ronaldo Alves Pinto Nagem

  32. Interleukin‐22 and Its Crystal Structure

    Article • January 2006, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  33. Crystallization and preliminary X-ray analysis of a novel Kunitz-type kallikrein inhibitor fromBauhinia bauhinioides

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2005, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  34. Getting the most out of X-ray home sources

    Article • Acta Crystallographica Section D Biological Crystallography, July 2005, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  35. Expression, purification, crystallization and preliminary X-ray analysis of YaeQ (XAC2396) fromXanthomonas axonopodispv.citri

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, April 2005, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  36. Crystal Structure of Exo-inulinase from Aspergillus awamori: The Enzyme Fold and Structural Determinants of Substrate Recognition

    Article • Journal of Molecular Biology, November 2004, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  37. Crystal Structures of β-Galactosidase from Penicillium sp. and its Complex with Galactose

    Article • Journal of Molecular Biology, November 2004, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  38. Crystal Structure of α-Galactosidase from Trichoderma reesei and Its Complex with Galactose: Implications for Catalytic Mechanism

    Article • Journal of Molecular Biology, May 2004, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  39. Three-dimensional structure of an unusual Kunitz (STI) type trypsin inhibitor from Copaifera langsdorffii

    Article • Biochimie, March 2004, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  40. Phasing on Rapidly Soaked Ions

    Article • January 2003, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  41. Crystal Structure of Recombinant Human Interleukin-22

    Article • Structure, August 2002, Elsevier

    Dr Ronaldo Alves Pinto Nagem

  42. Comparison of different crystal forms of 3-dehydroquinase fromSalmonella typhiand its implication for the enzyme activity

    Article • Acta Crystallographica Section D Biological Crystallography, April 2002, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  43. Crystallization and synchrotron X-ray diffraction studies of human interleukin-22

    Article • Acta Crystallographica Section D Biological Crystallography, February 2002, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  44. Direct way to anomalous scatterers

    Article • Zeitschrift für Kristallographie - Crystalline Materials, January 2002, De Gruyter

    Dr Ronaldo Alves Pinto Nagem

  45. Crystallization and preliminary X-ray diffraction analysis of a novel trypsin inhibitor from seeds ofCopaifera langsdorffii

    Article • Acta Crystallographica Section D Biological Crystallography, August 2001, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  46. Protein crystal structure solution by fast incorporation of negatively and positively charged anomalous scatterers

    Article • Acta Crystallographica Section D Biological Crystallography, June 2001, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  47. Crystallization and preliminary X-ray study of haem-binding protein from the bloodsucking insectRhodnius prolixus

    Article • Acta Crystallographica Section D Biological Crystallography, May 2001, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem

  48. Crystallization and preliminary X-ray diffraction studies of human catalase

    Article • Acta Crystallographica Section D Biological Crystallography, September 1999, International Union of Crystallography

    Dr Ronaldo Alves Pinto Nagem, Dr. Viviane Maimoni Goncalves