All Stories

  1. cis-cyclopropylamines as mechanism-based inhibitors of monoamine oxidases

    Article • FEBS Journal, March 2015, Wiley

    Dr Rona R. Ramsay

  2. Predicting targets of compounds against neurological diseases using cheminformatic methodology

    Article • Journal of Computer-Aided Molecular Design, November 2014, Springer Science + Business Media

    Dr John Mitchell, Dr Rona R. Ramsay

  3. Correction to Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

    Article • Journal of Chemical Information and Computer Sciences, July 2014, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  4. Interdisciplinary Chemical Approaches for Neuropathology

    Article • CNS Neuroscience & Therapeutics, June 2014, Wiley

    Dr Rona R. Ramsay

  5. Kinetic and structural analysis of the irreversible inhibition of human monoamine oxidases by ASS234, a multi-target compound designed for use in Alzheimer's disease

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, June 2014, Elsevier

    Dr Rona R. Ramsay

  6. Computational Comparison of Imidazoline Association with the I2 Binding Site in Human Monoamine Oxidases

    Article • Journal of Chemical Information and Computer Sciences, April 2014, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  7. Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique

    Article • Molecular BioSystems, January 2014, Royal Society of Chemistry

    Professor Angela Messina, Dr Rona R. Ramsay

  8. Inhibitor Design for Monoamine Oxidases

    Article • Current Pharmaceutical Design, March 2013, Bentham Science Publishers

    Dr Rona R. Ramsay

  9. Monoamine Oxidases: The Biochemistry of the Proteins As Targets in Medicinal Chemistry and Drug Discovery

    Article • Current Topics in Medicinal Chemistry, February 2013, Bentham Science Publishers

    Dr Rona R. Ramsay

  10. Monoamine Oxidases: The Biochemistry of the Proteins As Targets in Medicinal Chemistry and Drug Discovery

    Article • Current Topics in Medicinal Chemistry, October 2012, Bentham Science Publishers

    Dr Rona R. Ramsay

  11. An improved approach to steady-state analysis of monoamine oxidases

    Article • Journal of Neural Transmission, June 2011, Springer Science + Business Media

    Dr Rona R. Ramsay

  12. Dietary inhibitors of monoamine oxidase A

    Article • Journal of Neural Transmission, December 2010, Springer Science + Business Media

    Dr Rona R. Ramsay

  13. On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B

    Article • Pharmacological Research, December 2010, Elsevier

    Dr Rona R. Ramsay

  14. 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors

    Article • Bioorganic & Medicinal Chemistry, February 2010, Elsevier

    Dr Rona R. Ramsay

  15. TCP-FA4: A derivative of tranylcypromine showing improved blood–brain permeability

    Article • Biochemical Pharmacology, December 2009, Elsevier

    Dr Rona R. Ramsay

  16. Carnitine, mitochondrial function and therapy☆

    Article • Advanced Drug Delivery Reviews, November 2009, Elsevier

    Dr Rona R. Ramsay

  17. Characterization of the Covalently Bound Anionic Flavin Radical in Monoamine Oxidase A by Electron Paramagnetic Resonance

    Article • Journal of the American Chemical Society, December 2007, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  18. Interactions of imidazoline ligands with the active site of purified monoamine oxidase A

    Article • FEBS Journal, February 2007, Wiley

    Dr Rona R. Ramsay

  19. Orientation of oxazolidinones in the active site of monoamine oxidase

    Article • Biochemical Pharmacology, August 2005, Elsevier

    Dr Rona R. Ramsay

  20. The G553M Mutant of Peroxisomal Carnitine Octanoyltransferase Catalyses Acetyl Transfer and Acetyl-CoA Hydrolysis

    Article • Monatshefte für Chemie - Chemical Monthly, July 2005, Springer Science + Business Media

    Dr Rona R. Ramsay

  21. Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines

    Article • Bioorganic & Medicinal Chemistry, May 2005, Elsevier

    Dr Rona R. Ramsay

  22. Identification of 4-Substituted 1,2,3-Triazoles as Novel Oxazolidinone Antibacterial Agents with Reduced Activity against Monoamine Oxidase A

    Article • Journal of Medicinal Chemistry, January 2005, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  23. Conformational changes in monoamine oxidase A in response to ligand binding or reduction

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, April 2004, Elsevier

    Dr Rona R. Ramsay

  24. A snapshot of carnitine acetyltransferase

    Article • Trends in Biochemical Sciences, July 2003, Elsevier

    Professor James Henderson Naismith, Dr Rona R. Ramsay

  25. Interactions of D-amphetamine with the active site of monoamine oxidase-A

    Article • Inflammopharmacology, June 2003, Springer Science + Business Media

    Dr Rona R. Ramsay

  26. Monoamine oxidase A inhibitory potency and flavin perturbation are influenced by different aspects of pirlindole inhibitor structure

    Article • Biochemical Pharmacology, June 2003, Elsevier

    Dr Rona R. Ramsay

  27. Inhibitors alter the spectrum and redox properties of monoamine oxidase A

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, December 2002, Elsevier

    Dr Rona R. Ramsay

  28. Studies on the Characterization of the Inhibitory Mechanism of 4′-Alkylated 1-Methyl-4-Phenylpyridinium and Phenylpyridine Analogues in Mitochondria and Electron Transport Particles

    Article • Journal of Neurochemistry, November 2002, Wiley

    Dr Rona R. Ramsay

  29. Substrates but Not Inhibitors Alter the Redox Potentials of Monoamine Oxidases

    Article • Antioxidants & Redox Signaling, October 2001, Mary Ann Liebert Inc

    Dr Rona R. Ramsay

  30. The Role of the Carnitine System in Peroxisomal Fatty Acid Oxidation

    Article • The American Journal of the Medical Sciences, July 1999, Elsevier

    Dr Rona R. Ramsay

  31. A Brief History of Carnitine and its Presence in the CNS

    Article • January 1997, Springer Science + Business Media

    Dr Rona R. Ramsay

  32. Inhibition of Monoamine Oxidase A by β-Carboline Derivatives

    Article • Archives of Biochemistry and Biophysics, January 1997, Elsevier

    Dr Rona R. Ramsay

  33. Inhibition of NADH oxidation by 1-methyl-4-phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds

    Article • Journal of Biochemical Toxicology, January 1996, Wiley

    Dr Rona R. Ramsay, Sergey Bachurin

  34. Inhibition of NADH oxidation by 1‐methyl‐4‐phenylpyridinium analogs as the basis for the prediction of the inhibitory potency of novel compounds

    Article • Journal of Biochemical Toxicology, January 1996, Wiley

    Dr Rona R. Ramsay, Sergey Bachurin

  35. Syntheses, Structures, and Enzymic Evaluations of Conformationally Constrained, Analog Inhibitors of Carnitine Acetyltransferase: (2R,6R)-, (2S,6S)-, (2R,6S)-, and (2S,6R)-6-(Carboxylatomethyl)-2-(hydroxymethyl)-2,4,4-trimethylmorpholinium

    Article • The Journal of Organic Chemistry, October 1995, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  36. Deficiencies of NADH and succinate dehydrogenases in degenerative diseases and myopathies

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, May 1995, Elsevier

    Dr Rona R. Ramsay

  37. Chapter 3 Redox properties of the flavin cofactor of monoamine oxidases A and B and their relationship to the kinetic mechanism

    Article • January 1995, Elsevier

    Dr Rona R. Ramsay

  38. The reaction sites of rotenone and ubiquinone with mitochondrial NADH dehydrogenase

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, August 1994, Elsevier

    Dr Rona R. Ramsay

  39. Reactivation of NADH Dehydrogenase (Complex I) Inhibited by 1-Methyl-4-(4'-Alkylphenyl)pyridinium Analogues: A Clue to the Nature of the Inhibition Site

    Article • Journal of Neurochemistry, October 1993, Wiley

    Dr Rona R. Ramsay

  40. Oxidation of tetrahydrostilbazole by monoamine oxidase A demonstrates the effect of alternate pathways in the kinetic mechanism

    Article • Biochemistry, September 1993, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  41. Substrate-specific enhancement of the oxidative half-reaction of monoamine oxidase. [Erratum to document cited in CA118(13):119713e]

    Article • Biochemistry, May 1993, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  42. Substrate-specific enhancement of the oxidative half-reaction of monoamine oxidase

    Article • Biochemistry, March 1993, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  43. (+)-Hemipalmitoylcarnitinium strongly inhibits carnitine palmitoyltransferase-I in intact mitochondria

    Article • Journal of Medicinal Chemistry, January 1993, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  44. Relation of superoxide generation and lipid peroxidation to the inhibition of NADH-Q oxidoraductase by rotenone, piericidin A, and MPP+

    Article • Biochemical and Biophysical Research Communications, November 1992, Elsevier

    Dr Rona R. Ramsay

  45. Syntheses, structures, and enzymatic evaluations of hemiacylcarnitiniums, a new class of carnitine acyltransferase inhibitors

    Article • The Journal of Organic Chemistry, June 1992, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  46. Chapter 6 NADH-ubiquinone oxidoreductase

    Article • January 1992, Elsevier

    Dr Rona R. Ramsay

  47. Kinetic mechanism of monoamine oxidase A

    Article • Biochemistry, May 1991, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  48. Interaction of 1-Methyl-4-Phenylpyridinium Ion (MPP+) and Its Analogs with the Rotenone/Piericidin Binding Site of NADH Dehydrogenase

    Article • Journal of Neurochemistry, April 1991, Wiley

    Dr Rona R. Ramsay

  49. Mechanism of the neurotoxicity of MPTP

    Article • FEBS Letters, November 1990, Wiley

    Dr Rona R. Ramsay

  50. Palmitoyl-L-carnitine, a metabolic intermediate of the fatty acid incorporation pathway in erythrocyte membrane phospholipids

    Article • Biochemical and Biophysical Research Communications, November 1990, Elsevier

    Dr Rona R. Ramsay

  51. A new class of powerful inhibitors of monoamine oxidase A

    Article • Biochemical and Biophysical Research Communications, November 1990, Elsevier

    Dr Rona R. Ramsay

  52. Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone

    Article • Biochemical and Biophysical Research Communications, May 1990, Elsevier

    Dr Rona R. Ramsay

  53. Biochemical Reactions Leading to Parkinsonian Symptoms Elicited by MPTP

    Article • January 1990, Springer Science + Business Media

    Dr Rona R. Ramsay

  54. Oxidation of Analogs of l-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Monoamine Oxidases A and B and the Inhibition of Monoamine Oxidases by the Oxidation Products

    Article • Journal of Neurochemistry, December 1989, Wiley

    Dr Rona R. Ramsay

  55. In vitro effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria

    Article • Archives of Biochemistry and Biophysics, September 1989, Elsevier

    Dr Rona R. Ramsay

  56. Enhancement by tetraphenylboron of the interaction of the 1-methyl-4-phenylpyridinium ion (MPP+) with mitochondria

    Article • Biochemical and Biophysical Research Communications, March 1989, Elsevier

    Dr Rona R. Ramsay

  57. A case of carnitine palmitoyltransferase II deficiency in human skeletal muscle

    Article • FEBS Letters, December 1988, Wiley

    Dr Rona R. Ramsay

  58. Mechanism of the neurotoxicity of 1-methyl-4-phenylpyridinium (MPP)+, the toxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

    Article • Toxicology, April 1988, Elsevier

    Dr Rona R. Ramsay

  59. Biochemistry Of The Neurotoxic Action Of MPTP And What It May Teach Us About The Etiology Of Idiopathic Parkinsonism

    Article • January 1988, Springer Science + Business Media

    Dr Rona R. Ramsay

  60. The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

    Article • Archives of Biochemistry and Biophysics, December 1987, Elsevier

    Dr Rona R. Ramsay

  61. Inhibition of NADH oxidation by pyridine derivatives

    Article • Biochemical and Biophysical Research Communications, July 1987, Elsevier

    Dr Rona R. Ramsay

  62. Biochemical Events in the Development of Parkinsonism Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine

    Article • Journal of Neurochemistry, July 1987, Wiley

    Dr Rona R. Ramsay

  63. Stopped-flow studies on the mechanism of oxidation of N-methyl-4-phenyltetrahydropyridine by bovine liver monoamine oxidase B

    Article • Biochemistry, June 1987, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  64. Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP

    Article • Life Sciences, August 1986, Elsevier

    Dr Rona R. Ramsay

  65. Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

    Article • Biochemical and Biophysical Research Communications, February 1986, Elsevier

    Dr Rona R. Ramsay

  66. Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

    Article • Biochemical and Biophysical Research Communications, January 1986, Elsevier

    Dr Rona R. Ramsay

  67. Iron-Sulfur Clusters in Mitochondrial Enzymes

    Article • January 1985, Springer Science + Business Media

    Dr Rona R. Ramsay

  68. Two Small Peptides from Complex II and Their Role in the Reconstitution of Q Reductase Activity and in the Binding of TTF

    Article • January 1982, Elsevier

    Dr Rona R. Ramsay

  69. Relationship of the oxidation state of the iron sulfur cluster of aconitase to activity and substrate binding

    Article • Biochemistry, December 1981, American Chemical Society (ACS)

    Dr Rona R. Ramsay

  70. INHIBITORS OF CARNITINE TRANSPORT AND METABOLISM

    Article • January 1980, Elsevier

    Dr Rona R. Ramsay

  71. The Effects of Temperature and Some Inhibitors an the Carnitine Exchange System of Heart Mitochondria

    Article • European Journal of Biochemistry, October 1976, Wiley

    Dr Rona R. Ramsay

  72. The mechanism of fatty acid uptake by heart mitochondria: An acylcarnitine-carnitine exchange

    Article • FEBS Letters, June 1975, Wiley

    Dr Rona R. Ramsay

  73. Selective Modulation of Carnitine Long-chain Acyltransferase Activities

    Article • Springer Science + Business Media

    Dr Rona R. Ramsay