Contact

All Stories

  1. Electrospun Fiber‐Based Tubular Structures as 3D Scaffolds to Generate In Vitro Models for Small Intestine

    Article • Macromolecular Materials and Engineering, August 2024, Wiley

    Prof Roberto Giovannoni

  2. Impact of thermal processing on polyphenols, carotenoids, glucosinolates, and ascorbic acid in fruit and vegetables and their cardiovascular benefits

    Article • Comprehensive Reviews in Food Science and Food Safety, August 2024, Wiley

    Prof Roberto Giovannoni

  3. De Novo Genome Assembly at Chromosome-Scale of Hermetia illucens (Diptera Stratiomyidae) via PacBio and Omni-C Proximity Ligation Technology

    Article • Insects, February 2024, MDPI AG

    Prof Roberto Giovannoni

  4. Strategies for single base gene editing in an immortalized human cell line by CRISPR/Cas9 technology

    Article • 3 Biotech, January 2024, Springer Science + Business Media

    Prof Roberto Giovannoni

  5. Endothelial Effects of Simultaneous Expression of Human HO-1, E5NT, and ENTPD1 in a Mouse

    Article • Pharmaceuticals, October 2023, MDPI AG

    Prof Roberto Giovannoni

  6. Current Therapeutical Approaches Targeting Lipid Metabolism in NAFLD

    Article • International Journal of Molecular Sciences, August 2023, MDPI AG

    Prof Roberto Giovannoni

  7. DNAM-1 chimeric receptor-engineered NK cells: a new frontier for CAR-NK cell-based immunotherapy

    Article • Frontiers in Immunology, June 2023, Frontiers

    Prof Roberto Giovannoni

  8. Radiation dose-escalation and dose-fractionation modulate the immune microenvironment, cancer stem cells and vasculature in experimental high-grade gliomas

    Article • Journal of Neurosurgical Sciences, February 2023, Edizioni Minerva Medica

    Prof Roberto Giovannoni, dr Willy Gsell

  9. Tumor Microenvironment and Immune Escape in the Time Course of Glioblastoma

    Article • Molecular Neurobiology, September 2022, Springer Science + Business Media

    Prof Roberto Giovannoni

  10. CoCl2-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors

    Article • Biomedicines, June 2022, MDPI AG

    Prof Roberto Giovannoni

  11. News on immune checkpoint inhibitors as immunotherapy strategies in adult and pediatric solid tumors

    Article • Seminars in Cancer Biology, February 2022, Elsevier

    Prof Roberto Giovannoni

  12. Inhibition of plasminogen/plasmin system retrieves endogenous nerve growth factor and adaptive spinal synaptic plasticity following peripheral nerve injury

    Article • Neurochemistry International, September 2021, Elsevier

    Prof Roberto Giovannoni

  13. Pro64His (rs4644) Polymorphism Within Galectin-3 Is a Risk Factor of Differentiated Thyroid Carcinoma and Affects the Transcriptome of Thyrocytes Engineered via CRISPR/Cas9 System

    Article • Thyroid, July 2021, Mary Ann Liebert Inc

    Prof Roberto Giovannoni

  14. The Glioblastoma Microenvironment: Morphology, Metabolism, and Molecular Signature of Glial Dynamics to Discover Metabolic Rewiring Sequence

    Article • International Journal of Molecular Sciences, March 2021, MDPI AG

    Prof Roberto Giovannoni

  15. Rhabdomyosarcoma Cells Produce Their Own Extracellular Matrix With Minimal Involvement of Cancer-Associated Fibroblasts: A Preliminary Study

    Article • Frontiers in Oncology, January 2021, Frontiers

    Prof Roberto Giovannoni

  16. Radiotherapy, Temozolomide, and Antiprogrammed Cell Death Protein 1 Treatments Modulate the Immune Microenvironment in Experimental High-Grade Glioma

    Article • Neurosurgery, December 2020, Wolters Kluwer Health

    Prof Roberto Giovannoni, dr Willy Gsell

  17. BTK inhibitors synergise with 5‐FU to treat drug‐resistant TP53 ‐null colon cancers

    Article • The Journal of Pathology, December 2019, Wiley

    Prof Roberto Giovannoni

  18. HDL therapy today: from atherosclerosis, to stent compatibility to heart failure

    Article • Annals of Medicine, November 2019, Taylor & Francis

    Dr Massimiliano Ruscica, Prof Roberto Giovannoni

  19. Sperm-Mediated Genetic Modifications

    Article • September 2019, Springer Science + Business Media

    Prof Roberto Giovannoni

  20. CT-2A neurospheres-derived high-grade glioma in mice: a new model to address tumor stem cells and immunosuppression

    Article • Biology Open, September 2019, The Company of Biologists

    Prof Roberto Giovannoni, dr Willy Gsell

  21. p65BTK is a novel potential actionable target in KRAS-mutated/EGFR-wild type lung adenocarcinoma

    Article • Journal of Experimental & Clinical Cancer Research, June 2019, Springer Science + Business Media

    Prof Roberto Giovannoni

  22. The 1ALCTL and 1BLCTL isoforms of Arg/Abl2 induce fibroblast activation and extra cellular matrix remodelling differently

    Article • Biology Open, March 2019, The Company of Biologists

    Prof Roberto Giovannoni

  23. CHRNA2 and Nocturnal Frontal Lobe Epilepsy: Identification and Characterization of a Novel Loss of Function Mutation

    Article • Frontiers in Molecular Neuroscience, February 2019, Frontiers

    Prof Roberto Giovannoni

  24. Specific Expression of a New Bruton Tyrosine Kinase Isoform (p65BTK) in the Glioblastoma Gemistocytic Histotype

    Article • Frontiers in Molecular Neuroscience, January 2019, Frontiers

    Prof Roberto Giovannoni

  25. APOA-1Milano muteins, orally delivered via genetically modified rice, show anti-atherogenic and anti-inflammatory properties in vitro and in Apoe atherosclerotic mice

    Article • International Journal of Cardiology, November 2018, Elsevier

    Prof Roberto Giovannoni

  26. The Role of Hydrogen Peroxide in Redox-Dependent Signaling: Homeostatic and Pathological Responses in Mammalian Cells

    Article • Cells, October 2018, MDPI AG

    Prof Roberto Giovannoni

  27. Innovative and Efficient Oral Delivery Method of APOA-1Milano Muteins Which Retain Anti-Atherosclerotic and Anti-Inflammatory Properties

    Article • Atherosclerosis Supplements, June 2018, Elsevier

    Prof Roberto Giovannoni

  28. Metronomic combination of Vinorelbine and 5Fluorouracil is able to inhibit triple-negative breast cancer cells. Results from the proof-of-concept VICTOR-0 study

    Article • Oncotarget, May 2018, Impact Journals, LLC

    Prof Roberto Giovannoni

  29. CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells

    Article • Stem Cell Reports, April 2018, Elsevier

    Prof Roberto Giovannoni

  30. A Novel KCNJ2 Mutation Identified in an Autistic Proband Affects the Single Channel Properties of Kir2.1

    Article • Frontiers in Cellular Neuroscience, March 2018, Frontiers

    Prof Roberto Giovannoni

  31. Simultaneous overexpression of human E5NT and ENTPD1 protects porcine endothelial cells against H 2 O 2 -induced oxidative stress and cytotoxicity in vitro

    Article • Free Radical Biology and Medicine, July 2017, Elsevier

    Prof Roberto Giovannoni

  32. Abstract LB-282: Two different strategies of delivery CRISPR/Cas9 system to gene edit rs4644 SNP inLGALS3gene

    Article • Cancer Research, July 2017, American Association for Cancer Research (AACR)

    Prof Roberto Giovannoni

  33. Is metronomic vinorelbine (mVRL) able to inhibit both HUVEC and triple-negative breast cancer (TNBC) cells? The proof-of-concept VICTOR-0 study.

    Article • Journal of Clinical Oncology, May 2017, American Society of Clinical Oncology (ASCO)

    Prof Roberto Giovannoni

  34. Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway

    Article • PLoS ONE, January 2017, PLOS

    Prof Roberto Giovannoni

  35. Thyrospheres from B-CPAP Cell Line with BRAF and TERT Promoter Mutations have Different Functional and Molecular Features than Parental Cells

    Article • Journal of Cancer, January 2017, Ivyspring International Publisher

    Prof Roberto Giovannoni

  36. Unexpected frequency of genomic alterations in histologically normal colonic tissue from colon cancer patients

    Article • Tumor Biology, August 2016, Springer Science + Business Media

    Prof Roberto Giovannoni

  37. Platinum-Based Drugs and DNA Interactions Studied by Single-Molecule and Bulk Measurements

    Article • Biophysical Journal, May 2016, Elsevier

    Prof Roberto Giovannoni

  38. A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation

    Article • Oncogene, January 2016, Nature

    Prof Roberto Giovannoni

  39. Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-α-Induced Injury In Vitro

    Article • PLoS ONE, October 2015, PLOS

    Prof Roberto Giovannoni

  40. Circulating tumor cells and cholangiocarcinoma

    Article • Hepatology, October 2015, Wiley

    Prof Roberto Giovannoni

  41. A functional biological network centered on XRCC3: a new possible marker of chemoradiotherapy resistance in rectal cancer patients

    Article • Cancer Biology & Therapy, May 2015, Taylor & Francis

    Prof Roberto Giovannoni

  42. Co-expression of functional human Heme Oxygenase 1, Ecto-5′-Nucleotidase and ecto-nucleoside triphosphate diphosphohydrolase-1 by “self-cleaving” 2A peptide system

    Article • Plasmid, May 2015, Elsevier

    Prof Roberto Giovannoni

  43. SCN4A mutation as modifying factor of Myotonic Dystrophy Type 2 phenotype

    Article • Neuromuscular Disorders, April 2015, Elsevier

    Prof Roberto Giovannoni

  44. The TGF-β pathway is activated by 5-fluorouracil treatment in drug resistant colorectal carcinoma cells

    Article • Oncotarget, November 2014, Impact Journals, LLC

    Prof Roberto Giovannoni

  45. GSK3A Is Redundant with GSK3B in Modulating Drug Resistance and Chemotherapy-Induced Necroptosis

    Article • PLoS ONE, July 2014, PLOS

    Prof Roberto Giovannoni

  46. Functional Analysis of Expression of Human Ecto-Nucleoside Triphosphate Diphosphohydrolase-1 and/or Ecto-5′-Nucleotidase in Pig Endothelial Cells

    Article • Nucleosides Nucleotides & Nucleic Acids, April 2014, Taylor & Francis

    Prof Roberto Giovannoni

  47. Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury – Rescue by High-Dose Statin Treatment

    Article • PLoS ONE, November 2013, PLOS

    Prof Roberto Giovannoni

  48. Biliverdin Protects against Liver Ischemia Reperfusion Injury in Swine

    Article • PLoS ONE, July 2013, PLOS

    Prof Roberto Giovannoni

  49. Inhibition of GSK3B Bypass Drug Resistance of p53-Null Colon Carcinomas by Enabling Necroptosis in Response to Chemotherapy

    Article • Clinical Cancer Research, May 2013, American Association for Cancer Research (AACR)

    Prof Roberto Giovannoni

  50. Magnetic tweezers measurements of the nanomechanical stability of DNA against denaturation at various conditions of pH and ionic strength

    Article • Nucleic Acids Research, December 2012, Oxford University Press (OUP)

    Prof Roberto Giovannoni

  51. Methods for Sperm-Mediated Gene Transfer

    Article • August 2012, Springer Science + Business Media

    Prof Roberto Giovannoni

  52. Prevalence of Plasmid-Mediated Quinolone Resistance Genes in UropathogenicEscherichia coliIsolated in a Teaching Hospital of Northern Italy

    Article • Microbial Drug Resistance, February 2012, Mary Ann Liebert Inc

    Prof Roberto Giovannoni

  53. Importance of nitric oxide synthase in the anchoring structures of Neobenedenia girellae – an important fish parasite

    Article • Biochemical Systematics and Ecology, August 2011, Elsevier

    Prof Roberto Giovannoni

  54. AAV-mediated photoreceptor transduction of the pig cone-enriched retina

    Article • Gene Therapy, March 2011, Nature

    Prof Roberto Giovannoni

  55. Heme Oxygenase-1 Inhibition Prevents Intimal Hyperplasia Enhancing Nitric Oxide-Dependent Apoptosis of Vascular Smooth Muscle Cells

    Article • Biological and Pharmaceutical Bulletin, January 2011, Pharmaceutical Society of Japan

    Prof Roberto Giovannoni

  56. In Vitro Production of Multigene Transgenic Blastocysts via Sperm-Mediated Gene Transfer Allows Rapid Screening of Constructs to Be Used in Xenotransplantation Experiments

    Article • Transplantation Proceedings, July 2010, Elsevier

    Prof Roberto Giovannoni

  57. Pathogenetic role of hypercholesterolemia in a novel preclinical model of vascular injury in pigs

    Article • Atherosclerosis, December 2009, Elsevier

    Prof Roberto Giovannoni

  58. Head Glands of Monogenoidea: Morphology, Functionality, and Potentialities in Industrial Production of Surgery Bioadhesives

    Article • Journal of Parasitology, December 2009, American Society of Parasitologists

    Prof Roberto Giovannoni

  59. Sperm-mediated gene transfer–treated spermatozoa maintain good quality parameters and in vitro fertilization ability in swine

    Article • Theriogenology, December 2009, Elsevier

    Prof Roberto Giovannoni

  60. Reactive astrocytosis and glial glutamate transporter clustering are early changes in a spinocerebellar ataxia type 1 transgenic mouse model

    Article • Neuron Glia Biology, November 2007, Cambridge University Press

    Prof Roberto Giovannoni

  61. Reduction of hyperacute rejection and protection of metabolism and function in hearts of human decay accelerating factor (hDAF)-expressing pigs☆

    Article • Cardiovascular Research, January 2007, European Society of Cardiology

    Prof Roberto Giovannoni

  62. Genetically modified pigs produced with a nonviral episomal vector

    Article • Proceedings of the National Academy of Sciences, November 2006, Proceedings of the National Academy of Sciences

    Prof Roberto Giovannoni

  63. Sperm-mediated gene transfer

    Article • Reproduction Fertility and Development, January 2006, CSIRO Publishing

    Prof Roberto Giovannoni

  64. Multi-transgenic pigs expressing three fluorescent proteins produced with high efficiency by sperm mediated gene transfer

    Article • Molecular Reproduction and Development, January 2005, Wiley

    Prof Roberto Giovannoni

  65. Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs

    Article • The FASEB Journal, May 2004, Federation of American Societies For Experimental Biology (FASEB)

    Prof Roberto Giovannoni

  66. Dual Control of Neurogenesis by PC3 through Cell Cycle Inhibition and Induction of Math1

    Article • Journal of Neuroscience, March 2004, Society for Neuroscience

    Dr Felice Tirone, Prof Roberto Giovannoni

  67. Efficient production by sperm-mediated gene transfer of human decay accelerating factor (hDAF) transgenic pigs for xenotransplantation

    Article • Proceedings of the National Academy of Sciences, October 2002, Proceedings of the National Academy of Sciences

    Prof Roberto Giovannoni